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NIH funding notice RFA-HL-17-015

Bold New Bioengineering Methods and Approaches for Heart, Lung, Blood and Sleep Disorders and Diseases (R21)

Closed on September 7, 2018.

Posted
June 13, 2016
Close date
September 7, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
21
21 new
Median first-year cost
$229,800
$4,735,855 in all
Institutions
16
21 contact PIs
Patents
4
from 4 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. UNIVERSITY OF MICHIGAN AT ANN ARBOR3
  2. EMORY UNIVERSITY2
  3. MASSACHUSETTS GENERAL HOSPITAL2
  4. STANFORD UNIVERSITY2
  5. BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)1

and 11 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZHL1 CSR-O (M1))7
  2. Special Emphasis Panel (ZHL1 CSR-Q (O2))6
  3. Special Emphasis Panel (ZHL1 CSR-P (F1))4
  4. Special Emphasis Panel (ZHL1 CSR-O (O1))2
  5. Special Emphasis Panel (ZHL1 CSR-Q (F1))2
21 awards under RFA-HL-17-015 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2019Using a Cardiac Microtissue System to Evaluate and Replicate Clinical Therapy Responses using Patient Cell-Derived Exosomes1R21HL144244-01Taylor, Doris ATEXAS HEART INSTITUTE, TXFirst-year cost $244,500Study section ZHL1
FY2019Engineered Protein Oxygen Carriers: a novel blood substitute for trauma care1R21HL144224-01Moser, Christopher LSims, Carrie AdeliaUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $242,625Study section ZHL1
FY2019A New Pacing Approach for Cardioprotection and Repair in Heart Failure1R21HL144199-01Hodgson-Zingman, DeniceUNIVERSITY OF IOWA, IAFirst-year cost $241,160Study section ZHL1
FY2019Cryo-ET structural studies of platelets1R21HL146299-01Li, RenhaoWright, Elizabeth REMORY UNIVERSITY, GAFirst-year cost $234,000Study section ZHL1
FY2019ECM Shrink Wrapped Human Cardiomyocytes and Endothelial Cells to Accelerate Myocardial Regeneration1R21HL144235-01Feinberg, Adam WalterCARNEGIE-MELLON UNIVERSITY, PAFirst-year cost $214,518Study section ZHL1
FY2019Multi-functional targeted bio-conjugate platform to dismantle neutrophil extracellular traps (NETs)1R21HL144253-01Grinstaff, Mark W.Herrera, Victoria LRuiz-Opazo, NelsonBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MAFirst-year cost $206,250Study section ZHL1
FY2019Extracellular Matrix-Derived Nanoparticles for Repairing Lung Injury1R21HL146250-01Heise, Rebecca LongVIRGINIA COMMONWEALTH UNIVERSITY, VAFirst-year cost $181,005Study section ZHL1
FY2019Optical Mapping of Cardiac Electromechanics in the In Vivo Setting1R21HL140998-01A1Rogers, Jack MUNIVERSITY OF ALABAMA AT BIRMINGHAM, ALFirst-year cost $178,738Study section ZHL1
FY2018Portable CO2 servoregulation system for membrane lungs1R21HL140995-01Potkay, Joseph AllenUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $233,500Study section ZHL1
FY2018Point of Care Testing to Improve Monitoring of LVAD Patients1R21HL141028-01Chilkoti, AshutoshFranklin, AaronRogers, Joseph G.DUKE UNIVERSITY, NCFirst-year cost $229,922Study section ZHL1
FY2018Optical Pacing Using Graphene-Cardiomyocyte Interfaces for Precision Medicine and Drug Discovery1R21HL141019-01Mercola, MarkSTANFORD UNIVERSITY, CAFirst-year cost $229,800Study section ZHL1
FY2018Superomniphobic flow controlled prosthetic heart valve1R21HL139208-01Dasi, Lakshmi PrasadKota, Arun KumarPopat, Ketul ChandrakantOHIO STATE UNIVERSITY, OHFirst-year cost $228,830Study section ZHL1
FY2018Rapid breath analysis for acute respiratory distress syndrome diagnostics1R21HL139156-01Fan, XudongUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $225,166Study section ZHL1
FY2018Potentials of a Newly Engineered Device for Treatment of Neonatal Thrombocytopenia1R21HL141016-01Wu, Mei XMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $211,574Study section ZHL1
FY2017Utility of Vagal Stimulation to Prevent the Onset of Ventricular Arrhythmias1R21HL137870-01Armoundas, Antonis AMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $254,921Study section ZHL1
FY2017Engineered Protein Hydrogels to Modulate Adipose-derived Stromal Cell Secretome and Exosomes for Injectable Myocardial Infarction Therapy1R21HL138042-01Heilshorn, Sarah CSTANFORD UNIVERSITY, CAFirst-year cost $235,890Study section ZHL1
FY2017PET Imaging Probes Targeting Cardiac Parasympathetic Innervation1R21HL138054-01Raffel, David MUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $232,625Study section ZHL1
FY2017Cerebral Diffusion: A new approach to sleep disorders1R21HL138075-01Dubowitz, DavidUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $232,500Study section ZHL1
FY2017Use of a Variable Dead Space Rebreathe Device (Smart CO2) to Treat Obstructive and Central Sleep Apnea1R21HL137874-01Dempsey, Jerome AUNIVERSITY OF WISCONSIN-MADISON, WIFirst-year cost $229,500Study section ZHL1
FY2017Microvascular Cerebral Blood Flow Measured with Diffuse Correlation Spectroscopy in Children with Sickle Cell Disease1R21HL138062-01Buckley, Erin McGuireEMORY UNIVERSITY, GAFirst-year cost $224,581Study section ZHL1
FY2017Bioengineered peptibodies as antiarrhythmic therapy in atrial fibrillation1R21HL138064-01Noujaim, Sami FouadUNIVERSITY OF SOUTH FLORIDA, FLFirst-year cost $224,250Study section ZHL1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

4 patents name 4 of the 21 funded projects.

  1. US 12,281,161 (opens the patent at USPTO, a PDF, in a new tab)NOVEL POLYPEPTIDES AND USES THEREOFGranted April 22, 2025 to Trustees of Boston UniversityR21HL144253 · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA
  2. US 12,233,189 (opens the patent at USPTO, a PDF, in a new tab)Smart Artificial Lung And Perfusion SystemsGranted February 25, 2025 to THE REGENTS OF THE UNIVERSITY OF MICHIGAN and The United States Government as Represented by the Department of Veterans AffairsR21HL140995 · UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI
  3. US 11,014,971 (opens the patent at USPTO, a PDF, in a new tab)Peptibodies for the treatment of atrial fibrillationGranted May 25, 2021 to University of South FloridaR21HL138064 · UNIVERSITY OF SOUTH FLORIDA, FL
  4. US 10,442,166 (opens the patent at USPTO, a PDF, in a new tab)Hydrophilic, Yet Slippery SurfacesGranted October 15, 2019 to Colorado State University Research FoundationR21HL139208 · OHIO STATE UNIVERSITY, OH

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-13-0.3.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-HL-17-015: Bold New Bioengineering Methods and Approaches for Heart, Lung, Blood and Sleep Disorders and Diseases (R21) | ScienceDex | ConductScience