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NIH funding notice RFA-HL-19-018

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

Closed on July 9, 2020.

Posted
May 16, 2018
Close date
July 9, 2020
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
4
4 renewals
Median first-year cost
$999,517
$3,997,694 in all
Institutions
4
4 contact PIs
Patents
2
from 2 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. ARONORA, INC.1
  2. ELEX BIOTECH, LLC1
  3. FOX CHASE CHEMICAL DIVERSITY CENTER, INC1
  4. TRANSMURAL SYSTEMS, LLC1

Most frequent study sections

  1. Special Emphasis Panel (ZHL1 CSR-S (F1))2
  2. Special Emphasis Panel (ZHL1 CSR-A (F1))1
  3. Special Emphasis Panel (ZHL1 CSR-Q (F2))1
4 awards under RFA-HL-19-018 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2021Phase IIB Transmural Systems Transcatheter Cavopulmonary Bypass Endograft2R44HL147361-02A1Rafiee, NasserTRANSMURAL SYSTEMS, LLC, MAFirst-year cost $998,716Study section ZHL1
FY2020Factor XII Inhibitor for Surface Initiated Thrombosis2R44HL126235-04A1Lorentz, Christina UTucker, Erik IanARONORA, INC., ORFirst-year cost $999,930Study section ZHL1
FY2019Small Molecule Antagonists of PF4 for the Treatment and Prevention of HIT2R44HL123126-04Wrobel, Jay EdwardFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PAFirst-year cost $999,945Study section ZHL1
FY2019Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT2R44HL114206-04Kawahara, Douglas JELEX BIOTECH, LLC, ORFirst-year cost $999,103Study section ZHL1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

2 patents name 2 of the 4 funded projects.

  1. US 12,134,657 (opens the patent at USPTO, a PDF, in a new tab)THERAPEUTIC FACTOR XII ANTIBODYGranted November 5, 2024 to Oregon Health & Science University and Aronora, Inc.R44HL126235 · ARONORA, INC., OR
  2. US 11,427,542 (opens the patent at USPTO, a PDF, in a new tab)Compounds for treatment of cardiac arrhythmias and heart failureGranted August 30, 2022 to Elex Biotech, Inc.R44HL114206 · ELEX BIOTECH, LLC, OR

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-14-0.3.3. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-HL-19-018: NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) | ScienceDex | ConductScience