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NIH funding notice RFA-HL-26-016

Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)

Open. Closes December 23, 2027.

Posted
November 22, 2024
Close date
December 23, 2027
Activity codes
R33
Institutes taking part
NHLBI

The notices it replaced

2 notices since 2019, oldest first, each with its awards since FY2014.

  1. Posted 2019RFA-HL-20-02211 awards
  2. Posted 2022RFA-HL-23-0109 awards
  3. Posted 2024RFA-HL-26-016This notice, open · 4 awards

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
24
24 new
Median first-year cost
$477,623
$11,312,723 in all
Institutions
22
23 contact PIs

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. BRIGHAM AND WOMEN'S HOSPITAL2
  2. STANFORD UNIVERSITY2
  3. 3D BIOANALYTIX, INC.1
  4. ALBERT EINSTEIN COLLEGE OF MEDICINE1
  5. HALCYON BIOMEDICAL, INC.1

and 17 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZHL1 CSR-O (O1))6
  2. Special Emphasis Panel (ZHL1 CSR-O (F1))3
  3. Special Emphasis Panel (ZHL1 CSR-O (M2))3
  4. Special Emphasis Panel (ZRG1 MCST-Y (56))3
  5. Special Emphasis Panel (ZHL1 CSR-O (F2))2

and 5 other study sections

24 awards under RFA-HL-26-016 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2026A streamlined base editor reengineering platform to enhance gene editing specificity and selectivity1R33HL185498-01Jiang, TingtingICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NYFirst-year cost $570,666Study section ZRG1
FY2026High-throughput, multi-parametric assessment of cardiomyocyte viscoelasticity and contractility to enable HFpEF drug discovery1R33HL187274-01Mercola, MarkSTANFORD UNIVERSITY, CAFirst-year cost $509,334Study section ZRG1
FY2026A Transformative Structural Proteomics Platform for Early Detection of Misfolding-Driven Cardiovascular Diseases1R33HL185603-01Pankow, SandraYates Iii, John R3D BIOANALYTIX, INC., CAFirst-year cost $421,400Study section ZRG1
FY2026Development and validation of a cell separation platform technology1R33HL183009-01Gifford, SeanHALCYON BIOMEDICAL, INC., TXFirst-year cost $351,949Study section ZRG1
FY2025Drug Coated Balloon Peptide Delivery to Block Post-angioplasty Restenosis in PAD1R33HL181752-01 · under RFA-HL-23-010Duvall, Craig LewisVANDERBILT UNIVERSITY, TNFirst-year cost $489,644Study section ZHL1
FY2025Development of platform technology to measure kinetics and equilibrium concentration of sickle hemoglobin polymerization in single RBCs for drug potency assessment and patient risk stratification1R33HL173898-01A1 · under RFA-HL-23-010Higgins, John MatthewMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $483,852Study section ZHL1
FY2024Flexible bioelectronics platform converging capillary-like delivery network and sensing feedback network for improving cardiac tissue engineering1R33HL175683-01 · under RFA-HL-23-010Yao, JunUNIVERSITY OF MASSACHUSETTS AMHERST, MAFirst-year cost $488,026Study section ZHL1
FY2024A Novel Ticagrelor Coated Stent to Eliminate the Need for Dual Anti Platelet Therapy Post PCI1R33HL171775-01 · under RFA-HL-23-010Pacella, John JUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $481,245Study section ZHL1
FY2024Advancement of an Impending Hospitalization Detection Platform1R33HL168785-01A1 · under RFA-HL-23-010King, Kevin RUNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $474,000Study section ZHL1
FY2024Towards systematic analysis of cardiac voltage-gated sodium channel beta subunit function1R33HL168768-01A1 · under RFA-HL-23-010Ahern, Christopher APiper, Robert CUNIVERSITY OF IOWA, IAFirst-year cost $466,355Study section ZHL1
FY2023A New Lipid Nanoparticle Technology Enabling Long-acting mRNA Therapy1R33HL168751-01 · under RFA-HL-23-010Shi, JinjunBRIGHAM AND WOMEN'S HOSPITAL, MAFirst-year cost $542,677Study section ZHL1
FY2023Optimization of electromechanical monitoring of engineered heart tissues1R33HL168758-01 · under RFA-HL-23-010Efimov, Igor RMcNally, Elizabeth MRogers, JohnNORTHWESTERN UNIVERSITY AT CHICAGO, ILFirst-year cost $466,698Study section ZHL1
FY2023High throughput platform for simultaneous multiparametric assessment of cardiac physiology for heart failure drug development1R33HL167258-01A1 · under RFA-HL-23-010Mercola, MarkSTANFORD UNIVERSITY, CAFirst-year cost $463,200Study section ZHL1
FY2022The genetically engineered pig heart as a bridge to allotransplantation in infants1R33HL163718-01 · under RFA-HL-20-022Cleveland, David CUNIVERSITY OF ALABAMA AT BIRMINGHAM, ALFirst-year cost $488,333Study section ZHL1
FY2022MPI/MRI bimodal imaging for non-invasive tracking of extracellular vesicles targeted to infarcted myocardium1R33HL161756-01 · under RFA-HL-20-022Liu, GuanshuHUGO W. MOSER RES INST KENNEDY KRIEGER, MDFirst-year cost $487,071Study section ZHL1
FY2022Hyperpolarized Carbon-13 Metabolic MRI of the Human Heart1R33HL161816-01 · under RFA-HL-20-022Abraham, Maria RoselleLarson, Peder Eric ZufallUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $482,538Study section ZHL1
FY2022Beat-to-Beat Blood Pressure Monitoring During Sleep1R33HL163749-01 · under RFA-HL-20-022Kim, JoshuaVENA VITALS, INC., CAFirst-year cost $415,577Study section ZHL1
FY2022An Enabling Technology for Human Cardiomyocyte Manufacturing1R33HL163711-01 · under RFA-HL-20-022Lei, YuguoPENNSYLVANIA STATE UNIVERSITY, THE, PAFirst-year cost $413,610Study section ZHL1
FY2021Exhaled small RNA biomarkers to detect and monitor airway disease1R33HL156279-01 · under RFA-HL-20-022Loudig, OlivierSpivack, Simon DALBERT EINSTEIN COLLEGE OF MEDICINE, NYFirst-year cost $532,716Study section ZHL1
FY2021Dynamic tissue-specific modulation of redox stress using chemogenetics1R33HL157918-01 · under RFA-HL-20-022Michel, ThomasBRIGHAM AND WOMEN'S HOSPITAL, MAFirst-year cost $513,644Study section ZHL1
FY2021Developing EPR tools for preclinical interrogation of redox regulation mechanisms contributing to acute lung injury1R33HL157907-01 · under RFA-HL-20-022Eaton, Sandra S.Nozik, Eva S.UNIVERSITY OF COLORADO DENVER, COFirst-year cost $409,657Study section ZHL1
FY2020An inflammation-induced fibrosis-on-chip system for the testing of anti-fibrosis drugs1R33HL154117-01 · under RFA-HL-20-022Zhao, RuogangSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NYFirst-year cost $460,967Study section ZHL1
FY2020Development of a next-generation glycomics platform to enable glycan structure analyses for precision medicine1R33HL154123-01 · under RFA-HL-20-022Gundry, Rebekah L.UNIVERSITY OF NEBRASKA MEDICAL CENTER, NEFirst-year cost $458,564Study section ZHL1
FY2020Optimization of a Rabbit Retained Hemothorax Model for Evidence-Based Pharmacologic Interventions1R33HL154103-01 · under RFA-HL-20-022Florova, GalinaIdell, StevenKomissarov, AndreyUNIVERSITY OF TEXAS HLTH CTR AT TYLER, TXFirst-year cost $441,000Study section ZHL1
Newest fiscal year first, then first-year cost.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-14-0.3.3. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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