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NIH funding notice RFA-NS-17-004

BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01)

Closed on October 18, 2017.

Posted
September 29, 2016
Close date
October 18, 2017
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
15
15 new
Median first-year cost
$1,129,163
$33,605,459 in all
Institutions
13
15 contact PIs
Patents
5
from 4 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. STANFORD UNIVERSITY2
  2. UNIVERSITY OF CALIFORNIA BERKELEY2
  3. COLUMBIA UNIVERSITY HEALTH SCIENCES1
  4. CORNELL UNIVERSITY1
  5. JOHN B. PIERCE LABORATORY, INC.1

and 8 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZNS1 SRB-G (13))8
  2. Special Emphasis Panel (ZNS1 SRB-E (20))7
15 awards under RFA-NS-17-004 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2018Modular Systems for Large Scale, Long Lasting Measurements of Brain Activity1UF1NS107667-01Adesnik, HillelBrainard, Michael SBuffalo, Elizabeth ADenes, PeterFrank, Loren MHaque, Razi-UlKarlsson, Mattias PeterYorita, Allison MikaUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $6,069,247Study section ZNS1
FY2018High speed, high precision volumetric multiphoton neural control1UF1NS107574-01Adesnik, HillelUNIVERSITY OF CALIFORNIA BERKELEY, CAFirst-year cost $5,098,104Study section ZNS1
FY2018SCAPE microscopy for high-speed 3D imaging of cellular function in behaving animals: Continued innovation, optimization, and dissemination1UF1NS108213-01Hillman, Elizabeth M. C.COLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $3,529,762Study section ZNS1
FY2018Optimization and distribution of high density cellular scale carbon and silicon arrays1UF1NS107659-01Chestek, Cynthia AnneUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $3,433,739Study section ZNS1
FY2018An open source, wireless, miniature microscope for monitoring neuronal activity1UF1NS107668-01Basso, Michele AGolshani, PeymanUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $3,216,872Study section ZNS1
FY2018Transgenic mice and multiplexed, multi-beam instrumentation for large-scale optical experiments on brain states and ensemble cellular dynamics in behaving animals1UF1NS107610-01Schnitzer, Mark JZeng, HongkuiSTANFORD UNIVERSITY, CAFirst-year cost $2,867,445Study section ZNS1
FY2018Prototyping an ultrasound system for spatiotemporally precise noninvasive neuromodulatory drug uncaging and functional imaging in awake primates1UF1NS107666-01Caskey, Charles FVANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $1,989,689Study section ZNS1
FY2017Cortex-wide volumetric imaging of neuronal activity.1U01NS103488-01Vaziri, AlipashaROCKEFELLER UNIVERSITY, NYFirst-year cost $1,129,163Study section ZNS1
FY2017A microscope optimized for brain-scale 2-photon imaging1U01NS103518-01Pesaran, BijanNEW YORK UNIVERSITY, NYFirst-year cost $1,061,334Study section ZNS1
FY2017Bringing laser focus to voltage imaging: Enhanced indicators and advanced scanning methods for two-photon recording of dense networks in vivo1U01NS103464-01Dieudonne, StephaneLin, Michael Z.STANFORD UNIVERSITY, CAFirst-year cost $1,052,107Study section ZNS1
FY2017Genetically encoded indicators for large-scale sensing of neuromodulatory signaling in behaving animals1U01NS103522-01Nimmerjahn, AxelTian, LinVonzastrow, Mark EWilliams, John TUNIVERSITY OF CALIFORNIA AT DAVIS, CAFirst-year cost $978,456Study section ZNS1
FY2017High-speed volumetric imaging of neural activity throughout the living brain1U01NS103489-01Ji, NaUNIVERSITY OF CALIFORNIA BERKELEY, CAFirst-year cost $893,215Study section ZNS1
FY2017High Throughput of Protein-based Voltage Probes1U01NS103517-01Pieribone, Vincent AJOHN B. PIERCE LABORATORY, INC., CTFirst-year cost $823,310Study section ZNS1
FY2017Optimization of multiphoton microscopy for large scale activity mapping in adult zebrafish1U01NS103516-01Fetcho, Joseph R.Xu, ChrisCORNELL UNIVERSITY, NYFirst-year cost $754,207Study section ZNS1
FY2017Controlled neuronal firing in vivo using two photon spatially shaped optogenetics1U01NS099577-01A1Gibson, EmilyRestrepo, DiegoUNIVERSITY OF COLORADO DENVER, COFirst-year cost $708,809Study section ZNS1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

5 patents name 4 of the 15 funded projects.

  1. US 12,761,456 (opens the patent at USPTO, a PDF, in a new tab)Swept, Confocally-Aligned, Planar Excitation (SCAPE) Microscopy Using a Graded-Index (GRIN) LensGranted October 13, 2026 to The Trustees of Columbia University in the City of New YorkUF1NS108213 · COLUMBIA UNIVERSITY HEALTH SCIENCES, NY
  2. US 12,546,979 (opens the patent at USPTO, a PDF, in a new tab)Techniques for High-Speed Volumetric SamplingGranted February 10, 2026 to The Rockefeller UniversityU01NS103488 · ROCKEFELLER UNIVERSITY, NY
  3. US 12,459,985 (opens the patent at USPTO, a PDF, in a new tab)G-PROTEIN-COUPLED RECEPTOR INTERNAL SENSORSGranted November 4, 2025 to THE REGENTS OF THE UNIVERSITY OF CALIFORNIAU01NS103522 · UNIVERSITY OF CALIFORNIA AT DAVIS, CA
  4. US 12,367,557 (opens the patent at USPTO, a PDF, in a new tab)REMOVING INDEPENDENT NOISE USING DEEPINTERPOLATIONGranted July 22, 2025 to ALLEN INSTITUTEUF1NS107610 · STANFORD UNIVERSITY, CA
  5. US 11,988,603 (opens the patent at USPTO, a PDF, in a new tab)HIGH SPEED DEEP TISSUE IMAGING SYSTEM USING MULTIPLEXED SCANNED TEMPORAL FOCUSINGGranted May 21, 2024 to University of ViennaU01NS103488 · ROCKEFELLER UNIVERSITY, NY

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-12-0.3.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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