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NIH funding notice RFA-NS-22-034

HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)

Closed on December 6, 2024.

Posted
January 7, 2022
Close date
December 6, 2024
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

17 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $39,079,438 in first-year total cost, median $2,249,392.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ICN-Z (55)]8
  2. Special Emphasis Panel[ZRG1 IFCN-J (55)]5
  3. Special Emphasis Panel[ZRG1 ICN-J (55)]4

Most frequent institutions

  1. NEW YORK UNIVERSITY3
  2. DUKE UNIVERSITY2
  3. JOHNS HOPKINS UNIVERSITY2
  4. STANFORD UNIVERSITY2
  5. BOSTON CHILDREN'S HOSPITAL1
Competing awards under RFA-NS-22-034 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025A fully humanized functional genomic screen to identify and validate pain therapeutic targets1RF1NS142703-01PRICE, THEODORE J.UNIVERSITY OF TEXAS DALLAS, TX$4,039,366ZRG1
2025Targeting Succinate Signaling for Innovative Pain Relief in Oral Cancer.1R01DE035179-01LI, XINUNIVERSITY OF VIRGINIA, VA$3,892,146ZRG1
2025Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging1R01CA291906-01A1ZHENG, QINJOHNS HOPKINS UNIVERSITY, MD$2,714,830ZRG1
2025MicroRNA as a Novel Therapeutic Target for Pain in Sickle Cell Disease1RF1NS143697-01HE, YINGMIDWESTERN UNIVERSITY, IL$1,764,145ZRG1
2024Targeting Schwann cell dysfunction and repair signaling in chemotherapy induced painful peripheral neuropathy1R01DE033674-01CAMPANA, WENDY M.YE, YINEW YORK UNIVERSITY, NY$2,833,086ZRG1
2024Identification and validation of LPA/LPAR signaling as a target for the treatment of temporomandibular disorder pain1R01DE032676-01A1CHEN, YONGNACKLEY, ANDREA GDUKE UNIVERSITY, NC$2,372,116ZRG1
2024Validation of neuronal senescence as a target for chronic pain in aging1RF1AG088052-01TAWFIK, VIVIANNE LSTANFORD UNIVERSITY, CA$2,249,392ZRG1
2024Cellular Mechanisms and Therapeutic Potential of NR4A1 in Pain Resolution1RF1NS136108-01BERTA, TEMUGINUNIVERSITY OF CINCINNATI, OH$2,103,564ZRG1
2024Dissecting the role of mPFC dynorphin circuits in the modulation of different pain states1RF1NS132920-01A1SHEETS, PATRICK LINDIANA UNIVERSITY INDIANAPOLIS, IN$2,068,842ZRG1
2023Targeting checkpoint inhibitors for pain control1RF1NS131812-01A1JI, RU-RONGDUKE UNIVERSITY, NC$2,569,851ZRG1
2023Validation of a new large-pore channel as a novel target for neuropathic pain1RF1NS134549-01GUAN, YUNQIU, ZHAOZHUJOHNS HOPKINS UNIVERSITY, MD$2,039,202ZRG1
2023Validation of Neuropilin-1 Receptor Signaling in Nociceptive Processing1RF1NS131165-01A1KHANNA, RAJESHNEW YORK UNIVERSITY, NY$95,887ZRG1
2022Targeting HB-EGF and trigeminal EGFR for oral cancer pain and opioid tolerance1R01DE032501-01YE, YINEW YORK UNIVERSITY, NY$2,389,676ZRG1
2022PNPase inhibition as an effective treatment for chronic bladder pain1R01DK135076-01BIRDER, LORI AJACKSON, EDWIN KERRYUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$2,371,301ZRG1
2022Immune modulating therapies to treat complex regional pain syndrome1RF1NS130481-01AJIT, SEENADREXEL UNIVERSITY, PA$2,018,200ZRG1
2022Signal integration by specialized mesenchyme in urothelial homeostasis and Interstitial Cystitis / Bladder Pain Syndrome1R01DK134989-01BEACHY, PHILIP ASTANFORD UNIVERSITY, CA$1,799,384ZRG1
2022CMG2 as a target for safe and effective treatment of endometriosis-associate pain1R01HD110922-01ROGERS, MICHAEL SEANBOSTON CHILDREN'S HOSPITAL, MA$1,758,450ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-NS-22-034: HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed) | ScienceDex | ConductScience