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NIH funding notice RFA-NS-23-012

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Closed on May 1, 2023.

Posted
January 9, 2023
Close date
May 1, 2023
Activity codes
U01
Institutes taking part
NINDS, OD

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: RFA-NS-22-071 Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Replaced by RFA-NS-24-029.

Who won it before

4 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $50,667,952 in first-year total cost, median $11,197,636.

Most frequent study sections

  1. Special Emphasis Panel[ZNS1 SRB-E (05)]4

Most frequent institutions

  1. MASSACHUSETTS GENERAL HOSPITAL3
  2. COLUMBIA UNIVERSITY HEALTH SCIENCES1
Competing awards under RFA-NS-23-012 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Intermediate-Size Expanded Access Trial of Autologous Hybrid TREG/Th2 Cell Therapy (RAPA-501) of Amyotrophic Lateral Sclerosis1U01NS136020-01BABU, SUMABERRY, JAMES DALEPAGANONI, SABRINAMASSACHUSETTS GENERAL HOSPITAL, MA$11,203,040ZNS1
2023Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS).1U01NS136023-01ANDERSON, ERICANDREWS, JINSYGREENBERG, BENJAMIN MCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$11,192,232ZNS1
2023An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with Pridopidine1U01NS136021-01BABU, SUMABERRY, JAMES DALEPAGANONI, SABRINAMASSACHUSETTS GENERAL HOSPITAL, MA$10,136,176ZNS1
2022An Expanded Access Protocol of Intravenous Trehalose Injection 90 mg/mL Treatment of Patients with Amyotrophic Lateral Sclerosis1UF1NS131791-01 · under RFA-NS-22-071BABU, SUMABERRY, JAMES DALEPAGANONI, SABRINAMASSACHUSETTS GENERAL HOSPITAL, MA$18,136,504ZNS1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-12-0.1.3. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-NS-23-012: Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required) | ScienceDex | ConductScience