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NIH funding notice RFA-NS-28-010

BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)

Open. Closes February 8, 2029.

Posted
September 30, 2026
Close date
February 8, 2029
Activity codes
R01
Institutes taking part
NINDS, NEI, NIA, NIAAA, NIBIB, NICHD, NIDCD, NIDA, NIMH, NCCIH

The notices it replaced

5 notices since 2015, oldest first, each with its awards since FY2014.

  1. Posted 2015RFA-NS-16-0087 awards
  2. Posted 2016RFA-NS-17-0194 awards
  3. Posted 2017RFA-NS-18-0104 awards
  4. Posted 2018RFA-NS-19-00114 awards
  5. Posted 2022RFA-NS-22-0412 awards
  6. Posted 2026RFA-NS-28-010This notice, open

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
31
31 new
Median first-year cost
$1,089,050
$34,247,814 in all
Institutions
15
21 contact PIs
Patents
7
from 5 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA LOS ANGELES5
  2. BAYLOR COLLEGE OF MEDICINE3
  3. CALIFORNIA INSTITUTE OF TECHNOLOGY3
  4. MASSACHUSETTS GENERAL HOSPITAL3
  5. UNIVERSITY OF PITTSBURGH AT PITTSBURGH3

and 10 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZNS1 SRB-T (11))7
  2. Special Emphasis Panel (ZNS1 SRB-E (15))4
  3. Special Emphasis Panel (ZNS1 SRB-K (20))4
  4. Special Emphasis Panel (ZNS1 SRB-P (02))4
  5. Special Emphasis Panel (ZNS1 SRB-T (24))4

and 5 other study sections

31 awards under RFA-NS-28-010 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2024Laminar Circuit Motifs for Working Memory and Language Combinatorics: From Cells to Systems1U01NS137991-01 · under RFA-NS-22-041Petkov, Christopher IValiante, Taufik AYacoub, EssaUNIVERSITY OF IOWA, IAFirst-year cost $1,217,318Study section ZNS1
FY2023Modeling and Mapping Human Action Regulation Networks1U01NS132788-01 · under RFA-NS-22-041Christopoulos, Vasileios NPouratian, NaderUT SOUTHWESTERN MEDICAL CENTER, TXFirst-year cost $1,038,574Study section ZNS1
FY2022The Neural Code and Dynamics of the Reading Network1U01NS128921-01 · under RFA-NS-19-001Tandon, NitinUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TXFirst-year cost $1,254,299Study section ZNS1
FY2021Mapping Algorithmic State Space in the Human Brain1U01NS121472-01 · under RFA-NS-19-001Sheth, Sameer AnilBAYLOR COLLEGE OF MEDICINE, TXFirst-year cost $1,509,141Study section ZNS1
FY2021Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles1U01NS123128-01 · under RFA-NS-19-001Fried, ItzhakUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,478,534Study section ZNS1
FY2021Cortical basis of complex motor sequences in humans for neural interfaces1U01NS123101-01 · under RFA-NS-19-001Henderson, Jaimie MShenoy, Krishna VSTANFORD UNIVERSITY, CAFirst-year cost $1,273,915Study section ZNS1
FY2021Sensory motor transformations in human cortex1U01NS123127-01 · under RFA-NS-19-001Andersen, Richard ACALIFORNIA INSTITUTE OF TECHNOLOGY, CAFirst-year cost $1,082,090Study section ZNS1
FY2021Influence of task complexity and sensory feedback on cortical control of grasp force1U01NS123125-01 · under RFA-NS-19-001Collinger, Jennifer L.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $1,080,640Study section ZNS1
FY2021An integrated single-neuronal, population-, local network- and stimulation-based prefrontal investigation of human social cognition1U01NS121616-01 · under RFA-NS-19-001Williams, ZivMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $886,347Study section ZNS1
FY2021Computational neuroscience of language processing in the human brain1U01NS121471-01 · under RFA-NS-19-001Fedorenko, EvelinaRichardson, Robert MarkMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MAFirst-year cost $662,552Study section ZNS1
FY2020Neuronal mechanisms of human episodic memory1U01NS117839-01 · under RFA-NS-19-001Mamelak, Adam NathanielRutishauser, UeliCEDARS-SINAI MEDICAL CENTER, CAFirst-year cost $1,636,500Study section ZNS1
FY2020The neural coding of speech across human languages1U01NS117765-01 · under RFA-NS-19-001Chang, EdwardUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $1,271,864Study section ZNS1
FY2020Cortical-Basal Ganglia Speech Networks1U01NS117836-01 · under RFA-NS-19-001Richardson, Robert MarkMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $1,195,991Study section ZNS1
FY2020Neurostimulation and Recording of Real World Spatial Navigation in Humans1U01NS117838-01 · under RFA-NS-19-001Suthana, Nanthia AUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,089,050Study section ZNS1
FY2019Using Direct Brain Stimulation to Study Cognitive Electrophysiology1U01NS113198-01 · under RFA-NS-19-001Kahana, Michael JacobUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,467,616Study section ZNS1
FY2019Dynamic Neural Mechanisms of Audiovisual Speech Perception1U01NS113339-01 · under RFA-NS-19-001Beauchamp, Michael SSchroeder, Charles EBAYLOR COLLEGE OF MEDICINE, TXFirst-year cost $1,165,198Study section ZNS1
FY2018Causal mapping of emotion networks with concurrent electrical stimulation and fMRI1U01NS103780-01 · under RFA-NS-17-019Adolphs, RalphHoward, Matthew A.Poldrack, Russell ACALIFORNIA INSTITUTE OF TECHNOLOGY, CAFirst-year cost $1,002,070Study section ZNS1
FY2018Memory consolidation during sleep studied by direct neuronal recording and stimulation inside human brain1U01NS108930-01 · under RFA-NS-18-010Fried, ItzhakUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $970,511Study section ZNS1
FY2018Dynamics and Causal Functions of Large-Scale Cortical and Subcortical Networks1U01NS108916-01 · under RFA-NS-18-010Schalk, GerwinWADSWORTH CENTER, NYFirst-year cost $723,535Study section ZNS1
FY2018Mechanisms of Rapid, Flexible Cognitive Control in Human Prefrontal Cortex1U01NS108923-01 · under RFA-NS-18-010Sheth, Sameer AnilBAYLOR COLLEGE OF MEDICINE, TXFirst-year cost $704,586Study section ZNS1
FY2018Context-dependent processing in sensorimotor cortex1U01NS108922-01 · under RFA-NS-18-010Collinger, Jennifer L.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $611,562Study section ZNS1
FY2017Neuronal mechanisms of human episodic memory1U01NS103792-01 · under RFA-NS-17-019Mamelak, Adam NathanielRutishauser, UeliCEDARS-SINAI MEDICAL CENTER, CAFirst-year cost $1,223,572Study section ZNS1
FY2017Neurostimulation and Recording of Real World Spatial Navigation in Humans1U01NS103802-01 · under RFA-NS-17-019Suthana, Nanthia AUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,121,743Study section ZNS1
FY2017Intraoperative studies of flexible decision-making1U01NS103799-01 · under RFA-NS-17-019Baltuch, Gordon HGold, Joshua IUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $415,300Study section ZNS1
FY2016Understanding the Neural Basis of Volitional State through Continuous Recordings in Humans1U01NS098968-01 · under RFA-NS-16-008Cash, Sydney SMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $1,687,381Study section ZNS1
FY2016Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks1U01NS098961-01 · under RFA-NS-16-008Pouratian, NaderUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $1,339,820Study section ZNS1
FY2016Functional Architecture of Speech Motor Cortex1U01NS098971-01 · under RFA-NS-16-008Chang, EdwardUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $1,099,295Study section ZNS1
FY2016A unified cognitive network model of language1U01NS098981-01 · under RFA-NS-16-008Crone, Nathan ETandon, NitinUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TXFirst-year cost $1,063,151Study section ZNS1
FY2016Subthalamic and corticosubthalamic coding of speech production1U01NS098969-01 · under RFA-NS-16-008Richardson, Robert MarkUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $1,028,607Study section ZNS1
FY2016Dexterous BMIs for tetraplegic humans utilizing somatosensory cortex stimulation1U01NS098975-01 · under RFA-NS-16-008Andersen, Richard ACALIFORNIA INSTITUTE OF TECHNOLOGY, CAFirst-year cost $977,812Study section ZNS1
FY2016Dynamic Neural Mechanisms of Audiovisual Speech Perception1U01NS098976-01 · under RFA-NS-16-008Schroeder, Charles ECOLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $969,240Study section ZNS1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

7 patents name 5 of the 31 funded projects. The newest 5, by patent number.

  1. US 12,755,738 (opens the patent at USPTO, a PDF, in a new tab)Method of Contextual Speech Decoding From the BrainGranted October 6, 2026 to The Regents of the University of CaliforniaU01NS098971 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA
  2. US 12,678,081 (opens the patent at USPTO, a PDF, in a new tab)SYSTEMS AND METHODS FOR DETECTION OF NEUROPHYSIOLOGICAL SIGNAL OSCILLATIONSGranted July 14, 2026 to Washington UniversityU01NS108916 · WADSWORTH CENTER, NY
  3. US 12,654,013 (opens the patent at USPTO, a PDF, in a new tab)MEMORY ENHANCEMENT BY PREFRONTAL DEEP BRAIN STIMULATION SYNCHRONIZED TO MEDIAL TEMPORAL LOBE DURING SLEEPGranted June 16, 2026 to The Regents of the University of California and Ramot at Tel Aviv University Ltd.U01NS108930 · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA
  4. US 12,611,146 (opens the patent at USPTO, a PDF, in a new tab)SYSTEMS AND METHODS TO REMOVE BRAIN STIMULATION ARTIFACTS IN NEURAL SIGNALSGranted April 28, 2026 to WASHINGTON UNIVERSITYU01NS108916 · WADSWORTH CENTER, NY
  5. US 12,223,666 (opens the patent at USPTO, a PDF, in a new tab)METHODS FOR OPTIMIZING THE PLANNING AND PLACEMENT OF PROBES IN THE BRAIN VIA MULTIMODAL 3D ANALYSES OF CEREBRAL ANATOMYGranted February 11, 2025 to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMU01NS098981 · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-13-0.3.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-NS-28-010: BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed) | ScienceDex | ConductScience