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NIH funding notice RFA-RM-18-008

NIH Directors New Innovator Award Program (DP2 - Clinical Trial Optional)

Closed on September 10, 2018.

Posted
May 23, 2018
Close date
September 10, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

59 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $142,387,106 in first-year total cost, median $2,410,000.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 MOSS-R (70)]59

Most frequent institutions

  1. YALE UNIVERSITY4
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO3
  3. UNIVERSITY OF CALIFORNIA-IRVINE3
  4. BRIGHAM AND WOMEN'S HOSPITAL2
  5. CHILDREN'S HOSP OF PHILADELPHIA2
Competing awards under RFA-RM-18-008 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Intersectional Strategies to Understand the Function of Diverse Neural Circuits1DP2NS115764-01SCHWARZ, LINDSAY AST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$2,692,500ZRG1
2019A genetic approach to identify the common mechanisms of vascular disease1DP2HL152423-01GUPTA, RAJAT MBRIGHAM AND WOMEN'S HOSPITAL, MA$2,685,000ZRG1
2019The multifaceted role of acetate in cancer1DP2CA249950-01SCHUG, ZACHARY TWISTAR INSTITUTE, PA$2,679,000ZRG1
2019Positive Selection as a Host Mechanism to Control the Microbiome1DP2GM136652-01RAKOFF-NAHOUM, SETHBOSTON CHILDREN'S HOSPITAL, MA$2,655,000ZRG1
2019In utero CRISPR-mediated gene editing to cure congenital monogenic disorders1DP2HL152427-01PERANTEAU, WILLIAM H.CHILDREN'S HOSP OF PHILADELPHIA, PA$2,640,000ZRG1
2019Direct and rapid control of proteins at scale1DP2GM137416-01SHALEM, OPHIRCHILDREN'S HOSP OF PHILADELPHIA, PA$2,640,000ZRG1
2019Extracellular RNA Communication in Lung Inflammation1DP2HL152426-01PUA, HEATHER HVANDERBILT UNIVERSITY MEDICAL CENTER, TN$2,550,000ZRG1
2019Decoding ribosome-triggered quality control mechanisms1DP2GM137415-01SHAO, SICHENHARVARD MEDICAL SCHOOL, MA$2,542,500ZRG1
2019An integrative and generalizable approach to modulate microbiota small molecules in the host1DP2HD101401-01GUO, CHUN-JUNWEILL MEDICAL COLL OF CORNELL UNIV, NY$2,542,500ZRG1
2019How does the brain maximize storage capacity?1DP2MH122399-01CAI, DENISE JADEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$2,542,497ZRG1
2019Mapping Structure-Activity Relationships of Chemical Inhibitors via Genome-Editing1DP2GM137494-01LIAU, BRIANHARVARD UNIVERSITY, MA$2,535,000ZRG1
2019Single-cell epigenomic and cellular plasticity1DP2HL151353-01BUENROSTRO, JASON DANIELHARVARD UNIVERSITY, MA$2,535,000ZRG1
2019A Connectome-Based Clinical Trial Platform to Promote Early Recovery of Consciousness after Traumatic Coma1DP2HD101400-01EDLOW, BRIAN L.MASSACHUSETTS GENERAL HOSPITAL, MA$2,520,000ZRG1
2019Deciphering the Achilles Heel of Cancer Immunotherapy1DP2CA247831-01VILLANI, ALEXANDRA-CHLOEMASSACHUSETTS GENERAL HOSPITAL, MA$2,520,000ZRG1
2019Defining tumor cell and host adaptations in cancer progression1DP2CA248136-01MUZUMDAR, MANDAR DEEPAKYALE UNIVERSITY, CT$2,512,500ZRG1
2019Building the 3D genomic regulatome1DP2GM137414-01WANG, SIYUANYALE UNIVERSITY, CT$2,512,500ZRG1
2019Understand the little brain on the heart: a molecular and functional dissection of the intrinsic cardiac nervous system1DP2HL151354-01CHANG, RUIYALE UNIVERSITY, CT$2,512,500ZRG1
2019Elucidating the Role of a Novel Family of Chemoreceptor in Alzheimer's Disease1DP2AG067490-01GREER, PAUL LIEBERMANUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$2,512,500ZRG1
2019A forward chemical genetic screen to illuminate the dark matter of the bioactive microbiota metabolome1DP2DK125119-01PALM, NOAH WOLCOTTYALE UNIVERSITY, CT$2,512,500ZRG1
2019Protein complex assembly in the ER membrane1DP2GM137412-01VOORHEES, REBECCACALIFORNIA INSTITUTE OF TECHNOLOGY, CA$2,467,500ZRG1
2019A conserved function of amyloid proteins in host-microbiome interactions1DP2AG067492-01THAISS, CHRISTOPH ALEXANDERUNIVERSITY OF PENNSYLVANIA, PA$2,434,500ZRG1
2019Post-biotic interventions to ameliorate age-related inflammation1DP2AG067511-01LEVY, MAAYANUNIVERSITY OF PENNSYLVANIA, PA$2,434,500ZRG1
2019Probing Brain-wide Functional Connectivity During Behavior1DP2NS116768-01LEIFER, ANDREW MICHAELPRINCETON UNIVERSITY, NJ$2,430,000ZRG1
2019What makes - and breaks - a social brain?1DP2GM137424-01KOCHER, SARAH DPRINCETON UNIVERSITY, NJ$2,430,000ZRG1
2019Single cell detection of dynamic protein-RNA interaction1DP2GM137423-01ZHANG, XIAOCHANGUNIVERSITY OF CHICAGO, IL$2,430,000ZRG1
2019Modeling Neurodegenerative Disease Manifestations in Human Enteric Neurons1DP2NS116769-01FATTAHI, FARANAKUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$2,420,000ZRG1
2019Establishing A Stem Cell Biology Platform for Decoding the Genetic Basis of Human Brain Specializations1DP2MH122400-01POLLEN, ALEXANDER AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$2,418,334ZRG1
2019Reversing Autism linked behaviors from the Gut1DP2MH122402-01BOHORQUEZ, DIEGO VDUKE UNIVERSITY, NC$2,415,000ZRG1
2019A Human Stem Cell-Derived Podocyte Model for APOL1 Nephropathy1DP2DK124891-01OLABISI, OPEYEMI AYODEJIDUKE UNIVERSITY, NC$2,415,000ZRG1
2019A Regenerative Approach to Cardiac Pacing1DP2HL152425-01VEDANTHAM, VASANTHUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$2,410,000ZRG1
2019Unraveling fibrosis with dynamic microenvironments and molecular tools1DP2HL152424-01KLOXIN, APRIL MUNIVERSITY OF DELAWARE, DE$2,398,500ZRG1
2019Breathing life into dead enzymes1DP2GM137419-01TAGLIABRACCI, VINCENT SCOTTUT SOUTHWESTERN MEDICAL CENTER, TX$2,387,867ZRG1
2019Does the gut have a sense of touch?1DP2AT010875-01BEYDER, ARTHURMAYO CLINIC ROCHESTER, MN$2,385,000ZRG1
2019Decoding the fundamental mechanisms of tumor emergence and evolution1DP2CA250005-01CARMONA-FONTAINE, CARLOSNEW YORK UNIVERSITY, NY$2,377,500ZRG1
2019How Early-Life Experiences Create Individual Variation in Dopamine Circuit Architecture: Understanding Risk for Psychiatric Disease1DP2MH122401-01LERNER, TALIA NEWCOMBENORTHWESTERN UNIVERSITY AT CHICAGO, IL$2,370,000ZRG1
2019Bringing Light to Functional Mapping in Resective Neurosurgery1DP2EB029757-01DAYEH, SHADIUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$2,367,300ZRG1
2019Development of synthetic viral circuitry to regulate viruses in mosquito disease vectors1DP2AI152071-01AKBARI, OMAR SULTANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$2,367,250ZRG1
2019Dietary tuning of infant social communication1DP2HD102042-01O'CONNELL, LAUREN ASTANFORD UNIVERSITY, CA$2,365,500ZRG1
2019Resolving epigenetic instability during pluripotent state transitions: a roadmap for exploiting the biomedical potential of dynamic human stem cell states1DP2GM137418-01THEUNISSEN, THOROLDWASHINGTON UNIVERSITY, MO$2,361,375ZRG1
2019Engineering precision cancer immunotherapy1DP2CA247830-01DUPAGE, MICHELUNIVERSITY OF CALIFORNIA BERKELEY, CA$2,355,000ZRG1
2019New approaches to optimizing the application and measuring the impact of community-based tuberculosis interventions1DP2MD015102-01YUEN, COURTNEY M.BRIGHAM AND WOMEN'S HOSPITAL, MA$2,353,629ZRG1
2019Sculpting the brain: High-resolution spatiotemporally-controlled modulation of memories1DP2AG067666-01BEIER, KEVIN TUNIVERSITY OF CALIFORNIA-IRVINE, CA$2,352,500ZRG1
2019Spatial epigenomics: A new framework for overcoming mechanical heterogeneity in solid tumors1DP2CA250382-01DOWNING, TIMOTHY LAMONTUNIVERSITY OF CALIFORNIA-IRVINE, CA$2,352,500ZRG1
2019From non-coding to coding: uncovering the hidden coding potential of non-coding sequences and its role in de novo gene evolution1DP2GM137422-01CARVUNIS, ANNE-RUXANDRAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$2,347,500ZRG1
2019Nano-optical reporters of dynamic mechanotransduction in the immune system1DP2AI152072-01DIONNE, JENNIFER A.STANFORD UNIVERSITY, CA$2,347,500ZRG1
2019Communication between Networks: Context, Inhibition, and Neuromodulation1DP2MH122404-01RUNYAN, CAROLINE ANNEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$2,347,500ZRG1
2019Development of Compact CRISPR Editors for Multiplexed Editing of Complex Gene Networks1DP2HG011027-01NIU, JIABOSTON COLLEGE, MA$2,347,500ZRG1
2019High-Resolution Inference for Correlates of Vaccine Protection1DP2LM013340-01LUEDTKE, ALEXUNIVERSITY OF WASHINGTON, WA$2,332,500ZRG1
2019Big Data, Big Models, and Big Bias?: A decision making framework for vital rate estimates based on extrapolation1DP2MH122405-01MCCORMICK, TYLERUNIVERSITY OF WASHINGTON, WA$2,332,500ZRG1
2019Deciphering Cell-type Specific Regulatory Landscape in Human Brain1DP2MH122403-01WON, HYEJUNGUNIV OF NORTH CAROLINA CHAPEL HILL, NC$2,332,500ZRG1
2019Untangling the biology of brain wiring: high-throughput innovations for molecular screening and functional targeting of circuit development in vivo1DP2MH122398-01POULOPOULOS, ALEXANDROSUNIVERSITY OF MARYLAND BALTIMORE, MD$2,317,500ZRG1
2019An Integrative approach to elucidate glial diversity and its role in brain functionality1DP2NS117177-01SMITH, CODY J.UNIVERSITY OF NOTRE DAME, IN$2,317,500ZRG1
2019Paternal contributions to offspring health: Intergenerational epigenetic inheritance via sperm small RNAs1DP2AG066622-01SHARMA, UPASNAUNIVERSITY OF CALIFORNIA SANTA CRUZ, CA$2,310,000ZRG1
2019Connecting the dots between single molecule dynamics and cell differentiation1DP2GM136653-01LEGANT, WESLEY R.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$2,289,510ZRG1
2019Engineered platelets for the targeted destruction of circulating tumor cells1DP2CA250006-01DEANS, TARA LYNNUNIVERSITY OF UTAH, UT$2,287,500ZRG1
2019Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicines1DP2GM137427-01LI, HANUNIVERSITY OF CALIFORNIA-IRVINE, CA$2,240,841ZRG1
2019Engineering in vivo biomolecular synthesis with non-standard building blocks1DP2GM137417-01BULLER, ANDREWUNIVERSITY OF WISCONSIN-MADISON, WI$2,219,923ZRG1
2019Discovering novel small molecule antibiotics from complex microbial communities by integrating computational mass spectrometry and metagenome mining1DP2GM137413-01MOHIMANI, HOSEINCARNEGIE-MELLON UNIVERSITY, PA$2,191,726ZRG1
2019Spatial Control of Pattern Formation in Early Vertebrate Development1DP2HD102043-01SIMOES-COSTA, MARCOSCORNELL UNIVERSITY, NY$1,484,854ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-RM-18-008: NIH Directors New Innovator Award Program (DP2 - Clinical Trial Optional) | ScienceDex | ConductScience