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NIH funding notice RFA-RM-22-011

Somatic Mosaicism across Human Tissues (SMaHT) Program: Tool Development Projects (UG3/UH3 Clinical Trial Not Allowed)

Closed on July 8, 2022.

Posted
February 23, 2022
Close date
July 8, 2022
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

14 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $5,635,495 in first-year total cost, median $401,924.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 CDB-K (70)]14

Most frequent institutions

  1. BAYLOR COLLEGE OF MEDICINE2
  2. BOSTON CHILDREN'S HOSPITAL2
  3. BROAD INSTITUTE, INC.1
  4. CASE WESTERN RESERVE UNIVERSITY1
  5. DANA-FARBER CANCER INST1
Competing awards under RFA-RM-22-011 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Single molecule detection of L1 insertions and intermediates1UG3NS132127-01BERNSTEIN, BRADLEY EVANBURNS, KATHLEEN HLEE, EUNJUNG ALICEDANA-FARBER CANCER INST, MA$450,465ZRG1
2023Development of an Efficient High Throughput Technique for the Identification of High-Impact Non-Coding Somatic Variants Across Multiple Tissue Types1UG3NS132138-01PARK, PETER JWALSH, CHRISTOPHER A.BOSTON CHILDREN'S HOSPITAL, MA$448,340ZRG1
2023Detection and Characterization of Somatic Mutations in Human Tissue Utilizing Duplex-Consensus Sequencing1UG3NS132144-01CHOUDHURY, SANGITALEE, EUNJUNG ALICEWALSH, CHRISTOPHER A.BOSTON CHILDREN'S HOSPITAL, MA$442,498ZRG1
2023Ultra-High Fidelity Single-Molecule Profiling of Mosaic Double- and Single-Strand DNA Mutations and Damage1UG3NS132024-01EVRONY, GILAD DAVIDNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$438,048ZRG1
2023Single-Cell Multi-omics to Link Clonal Mosaicism (CM) Genotypes with Chromatin, Epigenomic, Transcriptomic and Protein Phenotypes1UG3NS132139-01LANDAU, DANSATIJA, RAHULWEILL MEDICAL COLL OF CORNELL UNIV, NY$428,151ZRG1
2023varCUT&Tag: A Method for Simultaneous Identification and Characterization of Sequence Variants in Regulatory Elements and Genes1UG3NS132136-01FAZZIO, THOMAS GGARBER, MANUELUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$418,750ZRG1
2023Simultaneous mapping of somatic mosaicism and kb-resolution 3D genome in single cells.1UG3NS132061-01JIN, FULAILI, YANCASE WESTERN RESERVE UNIVERSITY, OH$402,500ZRG1
2023Molecular and Computational Tools for Identifying Somatic Mosaicism in Human Tissues1UG3NS132084-01BOYLE, ALAN PMCCONNELL, MICHAEL J.MILLS, RYAN EUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$401,347ZRG1
2023Develop accurate high-coverage and high-throughput single-cell Duplex-seq chemistry and multi-omics platforms for simultaneous profiling of somatic mutation and the transcriptome in single human cells1UG3NS132132-01ZONG, CHENGHANGBAYLOR COLLEGE OF MEDICINE, TX$397,794ZRG1
2023Establishing and benchmarking advanced methods to comprehensively characterize somatic genome variation in single human cells1UG3NS132146-01URBAN, ALEXANDER ECKEHARTSTANFORD UNIVERSITY, CA$394,342ZRG1
2023A reference-free computational algorithm for comprehensive somatic mosaic mutation detection1UG3NS132134-01MARTH, GABOR TUNDERHILL, HUNTER REEVEUNIVERSITY OF UTAH, UT$384,588ZRG1
2023A Platform for Scalable Spatial Somatic Variant Profiling1UG3NS132135-01BUENROSTRO, JASON DANIELCHEN, FEIGETZ, GAD ABROAD INSTITUTE, INC., MA$368,192ZRG1
2023Hybrid approach for comprehensive mutation detection in a cell1UG3NS132128-01ABYZOV, ALEXEJMAYO CLINIC ROCHESTER, MN$365,664ZRG1
2023Identification of somatic/ mosaic SV and transposon activity and their crosstalk to DNA epigenetic Modifications1UG3NS132105-01SEDLAZECK, FRITZ JWU, TAOBAYLOR COLLEGE OF MEDICINE, TX$294,816ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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