Other Basic Sciences at Cleveland Clinic Lerner College of Medicine

Leads a grant in this department

111 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Jae U Jung

   Leads 6 awards · $3,721,115

   • 1U01CA294881-01Department: NIH department code

     Development of three KSHV vaccine platforms and chimeric MHV68-K-G for in vivo mouse infection study
     $989,903

     award amount
   • 1R01AI181758-01A1Department: NIH department code

     KSHV-mediated metabolic reprogramming for LANA expression and viral persistency
     $675,416

     award amount
   • 5R01AI171201-03Department: NIH department code

     Reassortment of Bunyavirus in ticks and animal models
     $577,846

     award amount
   • 5R01AI152190-05Department: NIH department code

     Tickborne SFTS Virus Vaccine Development
     $564,500

     award amount
   • 5R01CA251275-05Department: NIH department code

     Structural analysis and therapeutic nanobody development of KSHV G-protein coupled receptor
     $490,912

     award amount
   • 5R01DE023926-11Department: NIH department code

     KSHV Epigenetic Regulation
     $422,538

     award amount

2. Feixiong Cheng

   Leads 4 awards · $2,994,460

   • 5R01AG076448-03Department: NIH department code

     TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimer’s Disease

     Principal investigators: Feixiong Cheng (contact PI), Fei Wang, Li Gan

     $809,747

     award amount
   • 5U01AG073323-04Department: NIH department code

     Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics Discovery

     Principal investigators: Feixiong Cheng (contact PI), James Bruce Leverenz, Lynn Bekris

     $796,538

     award amount
   • 5R01AG082118-02Department: NIH department code

     Characterize neuronal and glial cell-specific vulnerability to proteinopathies in Alzheimer's disease using multimodal single-nuclei genomic and epigenomic approaches

     Principal investigators: Feixiong Cheng (contact PI), Andrew A Pieper, Borna Bonakdarpour, Margaret E Flanagan

     $796,355

     award amount
   • 5R01AG066707-05Department: NIH department code

     Endophenotype Network-based Approaches to Prediction and Population-based Validation of in Silico Drug Repurposing for Alzheimer’s Disease
     $591,820

     award amount

3. Michaela Ulrike Gack

   Leads 4 awards · $2,493,385

   • 5DP1AI169444-04Department: NIH department code

     Defining the viral PTMome: Towards the development of novel antiviral approaches
     $1,127,000

     award amount
   • 5R01AI165502-04Department: NIH department code

     Novel Role for Host Immunostimulatory RNA in Antiviral Immune Defense
     $459,982

     award amount
   • 5R01AI148534-05Department: NIH department code

     The Role of TRIM23 in Autophagy Mediated Antiviral Defenses
     $459,825

     award amount
   • 5R37AI087846-15Department: NIH department code

     Regulation of Host Innate Immunity Against Viral Infection
     $446,578

     award amount

4. Srinivasan Dasarathy

   Leads 6 awards · $2,421,931

   • 5U01DK130180-04Department: NIH department code

     Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapy
     $733,101

     award amount
   • 5R01AA028190-05Department: NIH department code

     Novel mechanism based treatment to improve tissue injury in alcoholic hepatitis

     Principal investigators: Srinivasan Dasarathy (contact PI), Laura E. Nagy

     $553,183

     award amount
   • 2U01AA026976-06Department: NIH department code

     Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD)- Cleveland Clinic Clinical Center

     Principal investigators: Srinivasan Dasarathy (contact PI), David Streem

     $354,195

     award amount
   • 5R01DK133905-02Department: NIH department code

     Mechanistic basis of exercise responses in liver disease
     $275,231

     award amount
   • 3U01DK130180-04S1Department: NIH department code

     Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapy
     $256,221

     award amount
   • 2U01DK061732-23Department: NIH department code

     Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland site
     $250,000

     award amount

5. Robert L Fairchild

   Leads 3 awards · $1,736,891

   • 5R01AI167939-03Department: NIH department code

     Chronic Antibody-Mediated Rejection of Kidney Allografts
     $646,362

     award amount
   • 5R01AI158421-04Department: NIH department code

     Acute Antibody Mediated Kidney Allograft Rejection
     $607,527

     award amount
   • 5R01AI040459-25Department: NIH department code

     Post-Transplant Inflammatory Response
     $483,002

     award amount

6. Stanley L Hazen

   Leads 2 awards · $1,574,396

   • 1R01HL167831-01A1Department: NIH department code

     Gut microbial dietary phenylalanine metabolism and heart failure
     $790,067

     award amount
   • 1R01HL169290-01A1Department: NIH department code

     Nutrition, terminal NAD metabolites and cardiovascular disease
     $784,329

     award amount

7. Paul L Fox

   Leads 3 awards · $1,549,755

   • 5R01NS124581-02Department: NIH department code

     Childhood-onset hypomyelinating leukodystrophy and the multi-tRNA synthetase complex

     Principal investigators: Paul L Fox (contact PI), Ranjan Dutta

     $607,836

     award amount
   • 5R01AG067146-05Department: NIH department code

     Adipokines, Aging, and Alzheimers Disease
     $474,473

     award amount
   • 5R01NS124547-03Department: NIH department code

     The mammalian multi-tRNA synthetase complex

     Principal investigators: Paul L Fox (contact PI), Valentin Gogonea

     $467,446

     award amount

8. Feng C Lin

   Leads 3 awards · $1,470,011

   • 1R61HL171747-01A1Department: NIH department code

     Development of a first-in-class complement inhibitor for treating complement-mediated hematologic diseases
     $563,500

     award amount
   • 5R01EY034077-02Department: NIH department code

     Role of CDCP1 in the pathogenesis of autoimmune uveitis
     $504,011

     award amount
   • 5R01EY032458-04Department: NIH department code

     New mechanisms by which complementýregulates the pathogenesis of experimental autoimmune uveitis
     $402,500

     award amount

9. Jacob Gardinier Scott

   Leads 6 awards · $1,387,564

   • 5U01CA280829-02Department: NIH department code

     Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modeling

     Principal investigators: Jacob Gardinier Scott (contact PI), Andriy Marusyk

     $507,671

     award amount
   • 5R37CA244613-05Department: NIH department code

     Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung Cancer
     $425,251

     award amount
   • 3U01CA280829-02S2Department: NIH department code

     Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modeling

     Principal investigators: Jacob Gardinier Scott (contact PI), Andriy Marusyk

     $203,444

     award amount
   • 3U01CA280829-02S1Department: NIH department code

     Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modeling

     Principal investigators: Jacob Gardinier Scott (contact PI), Andriy Marusyk

     $192,327

     award amount
   • 3U01CA280829-01S1Department: NIH department code

     Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modeling

     Principal investigators: Jacob Gardinier Scott (contact PI), Andriy Marusyk

     $33,742

     award amount
   • 3U01CA280829-01S2Department: NIH department code

     Extending experimental evolutionary game theory in cancer in vivo to enable clinical translation: integrating spatio-temporal dynamics using mathematical modeling

     Principal investigators: Jacob Gardinier Scott (contact PI), Andriy Marusyk

     $25,129

     award amount

10. Hod Michael Dana

    Leads 2 awards · $1,333,613

    • 5U01NS123658-03Department: NIH department code

      Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice

      Principal investigators: Hod Michael Dana (contact PI), Marie-Eve Paquet, Robert E. Campbell

      $699,930

      award amount
    • 1R01NS134577-01A1Department: NIH department code

      Calcium imaging-based insights and guidance of deep brain stimulation to enhance chronic, post-stroke rehabilitation in a rodent model of ischemia

      Principal investigators: Hod Michael Dana (contact PI), Kenneth B Baker

      $633,683

      award amount

11. Sathyamangla V Prasad

    Leads 2 awards · $1,188,475

    • 5R01HL162772-02Department: NIH department code

      Novel regulation of beta-adrenergic receptor function by phosphoinositide 3-kinase
      $624,975

      award amount
    • 1R61HL171717-01Department: NIH department code

      Small Molecule Therapeutic for Heart Failure

      Principal investigators: Sathyamangla V Prasad (contact PI), Vara Prasad Vn Josyula

      $563,500

      award amount

12. Laura E. Nagy

    Leads 2 awards · $1,169,811

    • 5R01AA030699-02Department: NIH department code

      IRAKM and MINCLE in ALD
      $602,163

      award amount
    • 2R01AA027456-04A1Department: NIH department code

      Transcriptional and non-transcriptional function of IRF3 in ALD
      $567,648

      award amount

    Also a principal investigator on 5R01AA028190-05, led by Srinivasan Dasarathy.

13. Hoonkyo Suh

    Leads 2 awards · $1,126,777

    • 5R01AA031028-02Department: NIH department code

      Activity and connectivity of hippocampal newborn neurons underlie alcohol withdrawal-associated syndromes
      $632,575

      award amount
    • 5R01AA027766-05Department: NIH department code

      The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognition
      $494,202

      award amount

14. Anna Valujskikh

    Leads 2 awards · $1,076,075

    • 5R01AI160740-04Department: NIH department code

      Mechanisms of alloantibody production following renal transplantation
      $596,809

      award amount
    • 5R01AI113142-09Department: NIH department code

      Designing induction therapies to target memory T cells in high risk recipients
      $479,266

      award amount

15. Ruth A. Keri

    Leads 4 awards · $1,064,056

    • 5R01CA257502-04Department: NIH department code

      Discovering the role of YES1 in triple negative breast cancer
      $438,269

      award amount
    • 3R01CA257502-04S2Department: NIH department code

      Supplement - Discovering the role of YES1 in triple negative breast cancer
      $365,768

      award amount
    • 1R21CA288795-01Department: NIH department code

      Targeting NEK2 to potentiate standard of care therapies for breast cancer
      $188,169

      award amount
    • 3R01CA257502-04S1Department: NIH department code

      Discovering the role of YES1 in triple negative breast cancer
      $71,850

      award amount

16. Kathleen Lucile Berkner

    Leads 2 awards · $1,054,476

    • 5R01HL158007-04Department: NIH department code

      Mechanisms controlling the efficiency of hemostatic vitamin K-dependent protein activation

      Principal investigators: Kathleen Lucile Berkner (contact PI), Kurt W Runge

      $538,321

      award amount
    • 5R01HL152678-04Department: NIH department code

      Impact of gamma-glutamyl carboxylase processivity on vitamin K-dependent protein modification and function in human health and disease

      Principal investigators: Kathleen Lucile Berkner (contact PI), Kurt W Runge

      $516,155

      award amount

17. Andrei Ivanovich Ivanov

    Leads 2 awards · $1,018,887

    • 1R01DK137822-01Department: NIH department code

      Actin methylation as a novel mechanism that regulates gut barrier integrity and repair
      $532,335

      award amount
    • 5R01DK131550-03Department: NIH department code

      Novel cytoskeletal mechanisms of pathogenic bacteria interactions with intestinal epithelium
      $486,552

      award amount

    Also a principal investigator on 5R01DK132038-02, led by Florian Rieder.

18. Xianfang Wu

    Leads 2 awards · $1,006,477

    • 1R01AA031226-01A1Department: NIH department code

      Studying alcohol-associated liver disease and its interaction with rs738409 variant in PNPLA3 in a liver culture model
      $523,477

      award amount
    • 5DP2AI170515-03Department: NIH department code

      Developing a renewable and dissectible human liver for the study of HBV/HCV infection
      $483,000

      award amount

19. Florian Rieder

    Leads 2 awards · $982,168

    • 5R01DK132038-02Department: NIH department code

      Septins in intestinal fibrosis

      Principal investigators: Florian Rieder (contact PI), Andrei Ivanovich Ivanov

      $604,875

      award amount
    • 5R01DK123233-05Department: NIH department code

      Creeping fat and Crohn's disease associated strictures
      $377,293

      award amount

20. Timothy An-Thy Chan

    Leads 1 award · $961,680

    • 5R35CA232097-08Department: NIH department code

      Towards Precision Immuno-Oncology: Unraveling the Genomic Determinants and Mechanisms Underlying Immunotherapy Efficacy and Resistance
      $961,680

      award amount

21. Jennifer S Yu

    Leads 2 awards · $921,230

    • 5R01NS124081-03Department: NIH department code

      lncRNA regulation of glioblastoma progression and therapeutic resistance

      Principal investigators: Jennifer S Yu (contact PI), Jianjun Zhao

      $530,805

      award amount
    • 5R01NS130798-02Department: NIH department code

      Sema3C Signaling as an Alternative Activator of Canonical Wnt Signaling in Glioblastoma
      $390,425

      award amount

22. Christine M O'Connor

    Leads 2 awards · $909,411

    • 5R01AI150931-04Department: NIH department code

      Manipulation of host factors that promote HCMV latency
      $473,567

      award amount
    • 5R01AI153348-04Department: NIH department code

      HCMV GPCR functions during latency and reactivation
      $435,844

      award amount

23. Jonathan D Smith

    Leads 2 awards · $902,915

    • 5R01HL156499-04Department: NIH department code

      Genetic modifiers of atherosclerosis and macrophage phenotypes
      $573,299

      award amount
    • 5T32GM137868-04Department: NIH department code

      Molecular Medicine Training Program at Cleveland Clinic/Case Western Reserve University
      $329,616

      award amount

24. Emilio Daniel Poggio

    Leads 2 awards · $901,823

    • 5U01DK129980-04Department: NIH department code

      Cleveland COPE-AKI Clinical Center

      Principal investigators: Emilio Daniel Poggio (contact PI), Anne Marie Huml, Sevag Demirjian

      $630,256

      award amount
    • 5U01DK116097-07Department: NIH department code

      7/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center

      Principal investigators: Emilio Daniel Poggio (contact PI), Mona Devang Doshi

      $271,567

      award amount

    Also a principal investigator on 5U01DK114908-08, led by John F. O'Toole.

25. Stephanie L. Schmit

    Leads 3 awards · $866,264

    • 5R01CA248931-04Department: NIH department code

      Variation in tumor-associated immune profiles and colorectal cancer outcomes
      $645,534

      award amount
    • 5R01CA238087-06Department: NIH department code

      Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral origins

      Principal investigators: Stephanie L. Schmit (contact PI), Jane C. Figueiredo

      $120,730

      award amount
    • 3R01CA248931-04S1Department: NIH department code

      Investigation of within-Latino heterogeneity in colorectal cancer mutational and T cell profiles
      $100,000

      award amount

26. Bruce D Trapp

    Leads 1 award · $845,598

    • 5R35NS097303-08Department: NIH department code

      Pathogenesis of Neurological Disability in Primary Diseases of Myelin
      $845,598

      award amount

27. Thaddeus S Stappenbeck

    Leads 1 award · $808,926

    • 1R01AI168411-01A1Department: NIH department code

      Innate immune responses to tissue infection by intestinal fungi inhibit wound repair

      Principal investigators: Thaddeus S Stappenbeck (contact PI), Deborah A Hogan

      $808,926

      award amount

28. Vidula Vachharajani

    Leads 2 awards · $794,801

    • 5R35GM149240-02Department: NIH department code

      Immune Function in Sepsis: Role of Sirtuin
      $402,500

      award amount
    • 5R01AA028763-04Department: NIH department code

      Immuno-metabolic dysfunction in alcohol with sepsis
      $392,301

      award amount

29. Tatiana V Byzova

    Leads 1 award · $783,003

    • 1R01AG082382-01A1Department: NIH department code

      Novel oxidative pathway targets microglia in Alzheimer's disease

      Principal investigators: Tatiana V Byzova (contact PI), Eugene A Podrez

      $783,003

      award amount

30. Peiwen Chen

    Leads 2 awards · $781,362

    • 7R01NS127824-02Department: NIH department code

      Targeting macrophage reprogramming in glioblastoma
      $390,937

      award amount
    • 7R01NS124594-03Department: NIH department code

      Mechanism and therapeutic potential of microglia regulation in glioblastoma
      $390,425

      award amount

31. Dawn Marie Taylor

    Leads 2 awards · $756,231

    • 5R01NS119160-05Department: NIH department code

      Improving intracortical control of reaching after paralysis

      Principal investigators: Dawn Marie Taylor (contact PI), Abidemi Bolu Ajiboye

      $554,981

      award amount
    • 5R21NS128685-02Department: NIH department code

      Targeting and Stimulating Cortical Area 3a to Restore Proprioception
      $201,250

      award amount

32. Shideng Bao

    Leads 2 awards · $740,299

    • 5R01NS128938-03Department: NIH department code

      Reprograming Macrophages and Targeting Glioma Stem Cells in Glioblastoma
      $390,425

      award amount
    • 5R01CA277966-02Department: NIH department code

      Macrophage-based Therapy and Immune Checkpoint Blockade for Glioblastoma
      $349,874

      award amount

33. John R. Sedor

    Leads 2 awards · $721,293

    • 5R01DK135265-02Department: NIH department code

      Mechanisms of Kidney Diseases Associated With APOL1 Variation

      Principal investigators: John R. Sedor (contact PI), John F. O'Toole, Leslie A Bruggeman, Oliver Wessely

      $656,893

      award amount
    • 3U2CDK129440-04S1Department: NIH department code

      Cleveland Kidney, Urology and Hematology Training Network

      Principal investigators: John R. Sedor (contact PI), Walter F Boron

      $64,400

      award amount

    Also a principal investigator on 5R01DK127638-04, led by Leslie A Bruggeman; 5U01DK114908-08, led by John F. O'Toole.

34. Mina Kay Chung

    Leads 1 award · $716,119

    • 5R01HL158071-04Department: NIH department code

      RADIOMIC APPROACHES TO IMPROVE TARGETING FOR ATRIAL FIBRILLATION CATHETER ABLATION

      Principal investigators: Mina Kay Chung (contact PI), Anant Madabhushi, John Barnard

      $716,119

      award amount

35. Keith R. McCrae

    Leads 1 award · $704,368

    • 5R01HL164516-02Department: NIH department code

      Mechanisms of cancer immunotherapy-associated thrombosis

      Principal investigators: Keith R. McCrae (contact PI), Alok A Khorana, Claudia Marcela Diaz-Montero

      $704,368

      award amount

36. Hannelore Heemers

    Leads 2 awards · $642,696

    • 5R01CA166440-11Department: NIH department code

      Toward Selective Androgen Deprivation by Targeting Androgen Activation of SRF
      $336,071

      award amount
    • 5R01CA248048-04Department: NIH department code

      A novel determinant of prostate cancer growth
      $306,625

      award amount

37. Justin D. Lathia

    Leads 1 award · $635,095

    • 5R35NS127083-03Department: NIH department code

      Contribution of Myeloid-Derived Suppressor Cells to Neuro-Inflammatory Alterations and Disease Progression in Glioblastoma
      $635,095

      award amount

38. Jaroslaw P. MacIejewski

    Leads 1 award · $632,461

    • 5R01DK131923-03Department: NIH department code

      Eltombopag: Novel Mode of Action on Normal and Aplastic Anemia Hematopoietic Stem Cells

      Principal investigators: Jaroslaw P. MacIejewski (contact PI), Babal K Jha

      $632,461

      award amount

39. William M Baldwin

    Leads 1 award · $625,596

    • 5R01AI165513-04Department: NIH department code

      Complement regulates macrophage and platelet function in kidney transplants
      $625,596

      award amount

40. Asha R Kallianpur

    Leads 2 awards · $620,098

    • 5R01MH124530-04Department: NIH department code

      Iron Dysregulation and Neuropsychiatric Complications of HIV Across the Lifespan: Impact of Biologic Factors, Antiretroviral Therapy and Genetics
      $411,519

      award amount
    • 5R21MH132532-02Department: NIH department code

      Quantitative Susceptibility Mapping of Brain Iron in People with HIV: Mechanistic Links to Neuropsychiatric Disorders

      Principal investigators: Asha R Kallianpur (contact PI), Xu Li

      $208,579

      award amount

41. Ignacio Fernandez Mata

    Leads 1 award · $589,629

    • 5R01NS112499-05Department: NIH department code

      Identifying novel Parkinson'’s disease genes exploring understudied Latino populations
      $589,629

      award amount

42. Ahmet Erdemir

    Leads 1 award · $578,104

    • 5R01EB024573-06Department: NIH department code

      Reproducibility in simulation-based prediction of natural knee mechanics

      Principal investigators: Ahmet Erdemir (contact PI), Jason Halloran

      $578,104

      award amount

43. Yuxin Wang

    Leads 1 award · $563,500

    • 1R01HL166544-01A1Department: NIH department code

      The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumonia
      $563,500

      award amount

44. Thomas M McIntyre

    Leads 1 award · $560,893

    • 5R01HL158669-04Department: NIH department code

      Hypertension augmented COVID-19 through renin-induced internalization of platelet-ACE2 / SARS-Cov-2 complexes
      $560,893

      award amount

45. Sarah Marie Schumacher

    Leads 1 award · $551,905

    • 5R01HL160755-03Department: NIH department code

      AS160 as a nodal regulator of the cardiac response to metabolic stress
      $551,905

      award amount

46. Jun Qin

    Leads 1 award · $550,409

    • 2R01HL058758-23A1Department: NIH department code

      Molecular basis of ILK-mediated cell adhesion
      $550,409

      award amount

47. Ina Nemet

    Leads 1 award · $546,944

    • 5R01HL160747-03Department: NIH department code

      Gut-microbial metabolism of aromatic amino acids and cardiovascular disease
      $546,944

      award amount

48. Leslie A Bruggeman

    Leads 1 award · $542,335

    • 5R01DK127638-04Department: NIH department code

      Intracellular functions of APOL1 in the kidney

      Principal investigators: Leslie A Bruggeman (contact PI), John F. O'Toole, John R. Sedor

      $542,335

      award amount

    Also a principal investigator on 5R01DK135265-02, led by John R. Sedor.

49. Dennis J Stuehr

    Leads 1 award · $536,531

    • 5R01GM148664-02Department: NIH department code

      Defining a pathway for mitochondrial heme trafficking
      $536,531

      award amount

50. Neetu Gupta

    Leads 1 award · $529,302

    • 5R01AI172916-02Department: NIH department code

      Novel unconventional myosins in B cell homeostasis
      $529,302

      award amount

51. Bin Zhang

    Leads 1 award · $518,074

    • 1R01HL169427-01A1Department: NIH department code

      Developing hemophilia A therapeutics by targeting translational and posttranslational regulation of FVIII
      $518,074

      award amount

52. Jonathan Mark Brown

    Leads 1 award · $510,429

    • 5R01DK130227-04Department: NIH department code

      Metaorganismal Endocrinology in Cardiometabolic Disease
      $510,429

      award amount

53. Gail Ann Cresci

    Leads 1 award · $509,758

    • 5R01AA028043-05Department: NIH department code

      Alcohol and intestinal microvascular endothelium-immune axis and the role of gut derived immune nutrients
      $509,758

      award amount

54. Christopher Michael Hine

    Leads 1 award · $499,693

    • 5R01NS127374-02Department: NIH department code

      Hydrogen sulfide functions as a tumor suppressor in glioblastoma
      $499,693

      award amount

55. Kenneth B Baker

    Leads 1 award · $487,636

    • 5R01NS116384-05Department: NIH department code

      Deep Brain Stimulation of the Cerebellar Dentate Nucleus to Enhance Chronic, Post-Traumatic Brain Injury Rehabilitation

      Principal investigators: Kenneth B Baker (contact PI), Andre Guelman MacHado

      $487,636

      award amount

    Also a principal investigator on 1R01NS134577-01A1, led by Hod Michael Dana.

56. Oliver Wessely

    Leads 1 award · $483,000

    • 5U01DK131383-04Department: NIH department code

      High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespan

      Principal investigators: Oliver Wessely (contact PI), Angela H Ting, Byron H Lee

      $483,000

      award amount

    Also a principal investigator on 5R01DK135265-02, led by John R. Sedor.

57. Jianjun Wu

    Leads 1 award · $467,502

    • 1R37CA288747-01Department: NIH department code

      Deciphering the Roles of STING-Mediated T cell Pyroptosis in Antitumor Immunity
      $467,502

      award amount

58. Jun Zhao

    Leads 1 award · $466,273

    • 1R01DE033632-01A1Department: NIH department code

      CDK6-dependent metabolic reprogramming in KSHV pathogenesis
      $466,273

      award amount

59. Ranjan Dutta

    Leads 1 award · $456,659

    • 5R01NS123532-03Department: NIH department code

      Understanding role of circadian disruption in pathogenesis of MS

      Principal investigators: Ranjan Dutta (contact PI), Sujata Rao

      $456,659

      award amount

    Also a principal investigator on 5R01NS124581-02, led by Paul L Fox.

60. Jianjun Zhao

    Leads 1 award · $449,002

    • 5R01CA251141-04Department: NIH department code

      New mouse model of cisplatin-induced AKI and development of prevention therapy
      $449,002

      award amount

    Also a principal investigator on 5R01NS124081-03, led by Jennifer S Yu.

61. Aaron W Miller

    Leads 1 award · $433,725

    • 5R01DK121689-05Department: NIH department code

      The role of acetogenic, methanogenic, and sulfate-reducing bacteria in oxalate metabolism and hyperoxaluria
      $433,725

      award amount

62. Jayati Basu

    Leads 1 award · $421,799

    • 1R01HL174794-01Department: NIH department code

      Transcriptional regulation of Myelopoiesis
      $421,799

      award amount

63. Rachel Greenberg Scheraga

    Leads 1 award · $416,964

    • 5R01HL155064-04Department: NIH department code

      TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury
      $416,964

      award amount

64. Li Lily Wang

    Leads 1 award · $413,971

    • 1R21CA286304-01A1Department: NIH department code

      Investigating a Novel Inhibitory Receptor in Regulating CAR-T Cell Persistence and Function
      $413,971

      award amount

65. Michelle S Longworth

    Leads 1 award · $406,794

    • 5R01GM147138-02Department: NIH department code

      Interplay between LINE-1 retrotransposons, condensins, and IFN
      $406,794

      award amount

66. Zihua Gong

    Leads 1 award · $405,116

    • 2R01CA222195-06A1Department: NIH department code

      The role of NUDT16 in DNA damage response and tumorigenesis
      $405,116

      award amount

67. Antoine Louveau

    Leads 1 award · $402,500

    • 5R56MH133584-02Department: NIH department code

      Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors
      $402,500

      award amount

68. Dianne M Perez

    Leads 1 award · $402,500

    • 5R01AG066627-05Department: NIH department code

      Early Stage Studies of a Novel Positive Allosteric Modulator of the Alpha1-Adrenergic Receptor to Treat Alzheimer's Disease
      $402,500

      award amount

69. Jan Claesen

    Leads 1 award · $402,500

    • 5R01AI153173-04Department: NIH department code

      Uncovering aryl polyene biology to identify new drug targets in Gram-negative bacterial pathogens
      $402,500

      award amount

70. Mitchell Alan Olman

    Leads 1 award · $402,500

    • 5R01HL158746-04Department: NIH department code

      Profibrotic Mechanisms of the TRPV4-PI3K-gamma Protein Complex
      $402,500

      award amount

71. Olga Cherepanova

    Leads 1 award · $402,500

    • 5R01HL150193-04Department: NIH department code

      Role of the TLR4 signaling in smooth muscle cell phenotypic transition
      $402,500

      award amount

72. Tara Maria Desilva

    Leads 1 award · $402,500

    • 5R01EY032342-04Department: NIH department code

      Mechanisms of retinal degeneration in neuroinflammatory demyelinating diseases
      $402,500

      award amount

73. Weiqiang Chen

    Leads 1 award · $402,500

    • 1R01DE033391-01Department: NIH department code

      Molecular mechanism of Zika virus-induced premature craniofacial suture closure
      $402,500

      award amount

74. Vinod D Labhasetwar

    Leads 1 award · $401,062

    • 5R01NS113680-05Department: NIH department code

      tPA nanoconjugate for stroke therapy
      $401,062

      award amount

75. Claudio Fiocchi

    Leads 1 award · $391,515

    • 5T32DK083251-14Department: NIH department code

      Combined Training Program in Digestive Disease Sciences

      Principal investigators: Claudio Fiocchi (contact PI), Fabio Cominelli

      $391,515

      award amount

76. Jessica L Williams

    Leads 1 award · $390,425

    • 5R01NS119178-04Department: NIH department code

      The role of the astrocyte immunoproteasome during chronic CNS autoimmunity
      $390,425

      award amount

77. Donal Luse

    Leads 1 award · $373,119

    • 2R01GM121428-05Department: NIH department code

      The effect of nucleosomes on the earliest stages of RNA polymerase II transcription
      $373,119

      award amount

78. Jennifer J Gassman

    Leads 1 award · $371,492

    • 1U24HL175028-01Department: NIH department code

      Master - 2/2 Empaglifozin To Improve Right Ventricular Function in Pulmonary Arterial Hypertension
      $371,492

      award amount

79. Cornelia Bergmann

    Leads 1 award · $367,000

    • 5R01NS086299-10Department: NIH department code

      Regulation of B cells in the CNS
      $367,000

      award amount

80. Ryota Matsuoka

    Leads 1 award · $367,000

    • 5R01NS117510-05Department: NIH department code

      Molecular Genetic Dissection of Fenestrated Vascular Development in the Choroid Plexus
      $367,000

      award amount

81. Raed A. Dweik

    Leads 1 award · $361,755

    • 5T32HL155005-04Department: NIH department code

      Supporting Multidisciplinary Achievement in Respiratory Research Training (SMARRT)
      $361,755

      award amount

82. Jan J Melenhorst

    Leads 1 award · $349,874

    • 5R01CA244958-04Department: NIH department code

      Mechanisms of nuclear Mcl-1 mediated chemoresistance
      $349,874

      award amount

83. Ying Ni

    Leads 1 award · $347,740

    • 5R01HD105049-03Department: NIH department code

      Modeling Autism and Comorbid Cancer Risk in Individuals with Germline PTEN Mutations

      Principal investigators: Ying Ni (contact PI), Thomas William Frazier

      $347,740

      award amount

84. Kenneth M. Merz

    Leads 1 award · $344,898

    • 2R01GM130641-05A1Department: NIH department code

      Modeling Transition Metal Ion Binding to Proteins
      $344,898

      award amount

85. Takuya Sakaguchi

    Leads 1 award · $340,032

    • 5R01DK103637-08Department: NIH department code

      Forward genetic analysis of biliary system formation
      $340,032

      award amount

86. Jeffrey L. Garvin

    Leads 1 award · $338,855

    • 5TL1DK132770-04Department: NIH department code

      KUH-TN Training Core
      $338,855

      award amount

87. John F. O'Toole

    Leads 1 award · $299,999

    • 5U01DK114908-08Department: NIH department code

      Cleveland Precision Medicine Chronic Kidney Disease Cohort

      Principal investigators: John F. O'Toole (contact PI), Emilio Daniel Poggio, John R. Sedor

      $299,999

      award amount

    Also a principal investigator on 5R01DK135265-02, led by John R. Sedor; 5R01DK127638-04, led by Leslie A Bruggeman.

88. Apollo Stacy

    Leads 1 award · $249,000

    • 5R00DE031372-03Department: NIH department code

      Role of sulfide in oral microbiota-host interactions that promote periodontitis
      $249,000

      award amount

89. James Michael Stolley

    Leads 1 award · $249,000

    • 5R00DE031014-04Department: NIH department code

      Regulation and Function of Oral Resident Memory T Cells
      $249,000

      award amount

90. Daniel James McGrail

    Leads 1 award · $248,999

    • 5R00CA240689-05Department: NIH department code

      Determining the Immunological Consequences of DNA Replication Stress Response Defects in Renal Cells Carcinoma to Improve Immunotherapy Outcomes
      $248,999

      award amount

91. Murat Yildirim

    Leads 1 award · $248,999

    • 5R00EB027706-05Department: NIH department code

      Developing next generation multiphoton systems to reveal cortico-thalamic interactions underlying short-term memory in behaving mice
      $248,999

      award amount

92. Nikhil Panicker

    Leads 1 award · $248,999

    • 5R00AG066862-05Department: NIH department code

      ASC oligomerization and transmission as an initiating event for protein aggregation in Synucleinopathy Dementias
      $248,999

      award amount

93. Jijun Xu

    Leads 1 award · $233,863

    • 5K08CA228039-05Department: NIH department code

      Complement in Paclitaxel-induced peripheral neuropathy
      $233,863

      award amount

94. Seth Joel Corey

    Leads 1 award · $227,857

    • 5R01DK132812-02Department: NIH department code

      Genetic Dissection of Stress Responses in Shwachman-Diamond Syndrome
      $227,857

      award amount

95. Brian P Rubin

    Leads 1 award · $225,803

    • 1R21CA288673-01Department: NIH department code

      Forging a new path with cyclin-dependent kinase inhibitors to treat epithelioid hemangioendothelioma

      Principal investigators: Brian P Rubin (contact PI), Ajaybabu Pobbati

      $225,803

      award amount

96. Vladimir Makarov

    Leads 1 award · $212,567

    • 1R50CA293821-01Department: NIH department code

      Immunogenomics platform for the analysis of cancer
      $212,567

      award amount

97. Jianguo Wu

    Leads 1 award · $187,444

    • 5K01AA029474-04Department: NIH department code

      The role of PDK4 in alcohol-associated liver disease
      $187,444

      award amount

98. Nicole Welch

    Leads 1 award · $179,129

    • 5K08AA028794-04Department: NIH department code

      Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver disease
      $179,129

      award amount

99. Michael P. Berk

    Leads 1 award · $165,535

    • 5R50CA251961-05Department: NIH department code

      Translational science specialist in genitourinary cancers
      $165,535

      award amount

100. Richa Sharma

     Leads 1 award · $162,204

     • 7K08DK134873-04Department: NIH department code

       Consequences of gain-of-function RPA1 mutations on telomere function and hematopoiesis
       $162,204

       award amount

101. Erin E. Mulkearns-Hubert

     Leads 1 award · $161,000

     • 1R03NS135197-01A1Department: NIH department code

       Connexin 43 drives glioblastoma cancer stem cells through a WNK1 signaling axis
       $161,000

       award amount

102. John J Elias

     Leads 1 award · $161,000

     • 1R01AR084758-01Department: NIH department code

       Evaluating Over Constraint of the Patella following MPFL Reconstruction as a Contributing Factor to Progressive Cartilage Degradation

       Principal investigators: John J Elias (contact PI), Xiaojuan Li

       $161,000

       award amount

103. Logan Harper

     Leads 1 award · $159,904

     • 5K23MD017284-03Department: NIH department code

       Improving Black sarcoidosis patients’ care with a collaboratively developed, patient centered program
       $159,904

       award amount

104. Natalie Lea Silver

     Leads 1 award · $155,304

     • 5K08DE029503-06Department: NIH department code

       Remodeling host immunity in oral cancer with personalized RNA nanoparticle vaccines
       $155,304

       award amount

105. Benjamin C. Shaw

     Leads 1 award · $84,499

     • 5K00NS120365-04Department: NIH department code

       Translating Genetic Risk Factors to Therapies: From Big Data to Druggable Targets
       $84,499

       award amount

106. Julie Y. Zhou

     Leads 1 award · $76,828

     • 1F32DK136180-01A1Department: NIH department code

       Internalization of dead cells governs intestinal stem cell activity
       $76,828

       award amount

107. Anthony Robert Sloan

     Leads 1 award · $75,928

     • 1F32CA287655-01A1Department: NIH department code

       A Hyper-Thrombotic State and Immunosuppression in GBM
       $75,928

       award amount

108. Mary Talley

     Leads 1 award · $74,284

     • 1F32HD114499-01Department: NIH department code

       The role of retrotransposonable elements in neurodevelopment and disease
       $74,284

       award amount

109. Erik Harrison Koritzinsky

     Leads 1 award · $53,974

     • 5F30AI174667-02Department: NIH department code

       Endogenous memory T cell mediated rejection of high-risk cardiac allografts
       $53,974

       award amount

110. Taylor Lynn Brzozowski

     Leads 1 award · $48,684

     • 1F31CA284668-01A1Department: NIH department code

       Ribonucleotide Reductase as a Driver of Breast Cancer Aggressiveness
       $48,684

       award amount

111. Lauren Elizabeth Haines

     Leads 1 award · $38,108

     • 5F31DK135368-02Department: NIH department code

       Human iPSC-derived Podocytes to Study APOL1 High-Risk Variants
       $38,108

       award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Kurt W Runge

  Co-investigator on 5R01HL158007-04, led by Kathleen Lucile Berkner; 5R01HL152678-04, led by Kathleen Lucile Berkner

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Andriy Marusyk

  Co-investigator on 5U01CA280829-02, led by Jacob Gardinier Scott; 3U01CA280829-02S2, led by Jacob Gardinier Scott; 3U01CA280829-02S1, led by Jacob Gardinier Scott; 3U01CA280829-01S1, led by Jacob Gardinier Scott; 3U01CA280829-01S2, led by Jacob Gardinier Scott

  From the FY2024 awards this person leads

  • Moffitt Cancer Center (no department on record, 1 award)

• Fei Wang

  Co-investigator on 5R01AG076448-03, led by Feixiong Cheng

  From the FY2024 awards this person leads

  • Weill Cornell Medicine · Public Health (NIH department code, 3 awards)

• Li Gan

  Co-investigator on 5R01AG076448-03, led by Feixiong Cheng

  From the FY2024 awards this person leads

  • Weill Cornell Medicine · Neurosciences (NIH department code, 1 award)

• Deborah A Hogan

  Co-investigator on 1R01AI168411-01A1, led by Thaddeus S Stappenbeck

  From the FY2024 awards this person leads

  • Dartmouth College · Microbiology & Immunology (NIH department code, 3 awards)
  • Dartmouth College (no department on record, 1 award)

• James Bruce Leverenz

  Co-investigator on 5U01AG073323-04, led by Feixiong Cheng

  From the FY2024 awards this person leads

  • Cleveland Clinic Lerner College of Medicine · Internal Medicine (NIH department code, 1 award)

• Lynn Bekris

  Co-investigator on 5U01AG073323-04, led by Feixiong Cheng

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Andrew A Pieper

  Co-investigator on 5R01AG082118-02, led by Feixiong Cheng

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Borna Bonakdarpour

  Co-investigator on 5R01AG082118-02, led by Feixiong Cheng

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Margaret E Flanagan

  Co-investigator on 5R01AG082118-02, led by Feixiong Cheng

  From the FY2024 awards this person leads

  • UT Health Science Center Houston · Pathology (NIH department code, 1 award)
  • Northwestern University (no department on record, 1 award)

• Eugene A Podrez

  Co-investigator on 1R01AG082382-01A1, led by Tatiana V Byzova

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Anant Madabhushi

  Co-investigator on 5R01HL158071-04, led by Mina Kay Chung

  From the FY2024 awards this person leads

  • Emory University · Biomedical Engineering (NIH department code, 4 awards)
  • Case Western Reserve University (no department on record, 1 award)

• John Barnard

  Co-investigator on 5R01HL158071-04, led by Mina Kay Chung

  From the FY2024 awards this person leads

  • Cleveland Clinic Lerner College of Medicine (no department on record, 1 award)

• Alok A Khorana

  Co-investigator on 5R01HL164516-02, led by Keith R. McCrae

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Claudia Marcela Diaz-Montero

  Co-investigator on 5R01HL164516-02, led by Keith R. McCrae

  From the FY2024 awards this person leads

  • Cleveland Clinic Lerner College of Medicine (no department on record, 1 award)

• Marie-Eve Paquet

  Co-investigator on 5U01NS123658-03, led by Hod Michael Dana

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Robert E. Campbell

  Co-investigator on 5U01NS123658-03, led by Hod Michael Dana

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Babal K Jha

  Co-investigator on 5R01DK131923-03, led by Jaroslaw P. MacIejewski

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Anne Marie Huml

  Co-investigator on 5U01DK129980-04, led by Emilio Daniel Poggio

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sevag Demirjian

  Co-investigator on 5U01DK129980-04, led by Emilio Daniel Poggio

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Jason Halloran

  Co-investigator on 5R01EB024573-06, led by Ahmet Erdemir

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Vara Prasad Vn Josyula

  Co-investigator on 1R61HL171717-01, led by Sathyamangla V Prasad

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Abidemi Bolu Ajiboye

  Co-investigator on 5R01NS119160-05, led by Dawn Marie Taylor

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Andre Guelman MacHado

  Co-investigator on 5R01NS116384-05, led by Kenneth B Baker

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Angela H Ting

  Co-investigator on 5U01DK131383-04, led by Oliver Wessely

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Byron H Lee

  Co-investigator on 5U01DK131383-04, led by Oliver Wessely

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Valentin Gogonea

  Co-investigator on 5R01NS124547-03, led by Paul L Fox

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sujata Rao

  Co-investigator on 5R01NS123532-03, led by Ranjan Dutta

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Fabio Cominelli

  Co-investigator on 5T32DK083251-14, led by Claudio Fiocchi

  From the FY2024 awards this person leads

  • Case Western Reserve University · Internal Medicine (NIH department code, 2 awards)
  • Case Western Reserve University (no department on record, 1 award)

• David Streem

  Co-investigator on 2U01AA026976-06, led by Srinivasan Dasarathy

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Thomas William Frazier

  Co-investigator on 5R01HD105049-03, led by Ying Ni

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Mona Devang Doshi

  Co-investigator on 5U01DK116097-07, led by Emilio Daniel Poggio

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Ajaybabu Pobbati

  Co-investigator on 1R21CA288673-01, led by Brian P Rubin

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Xu Li

  Co-investigator on 5R21MH132532-02, led by Asha R Kallianpur

  From the FY2005 awards this person leads

  • Ohio University Athens (no department on record, 1 award)

• Xiaojuan Li

  Co-investigator on 1R01AR084758-01, led by John J Elias

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Jane C. Figueiredo

  Co-investigator on 5R01CA238087-06, led by Stephanie L. Schmit

  From the FY2024 awards this person leads

  • Cedars-Sinai Medical Center · Internal Medicine (topic-inferred, 2 awards)
  • Cedars-Sinai Medical Center · Psychiatry (topic-inferred, 1 award)
  • Cedars-Sinai Medical Center · Genetics (topic-inferred, 1 award)

• Walter F Boron

  Co-investigator on 3U2CDK129440-04S1, led by John R. Sedor

  From the FY2024 awards this person leads

  • Case Western Reserve University · Physiology (NIH department code, 2 awards)