Pathology at Columbia University

Leads a grant in this department

63 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Myeku, Natura

   Leads 3 awards · $3,000,354

   • 1RF1AG070075-01A1Department: NIH department code

     The Role of Immunoproteasome Function in Alzheimer's Disease and Aging
     $2,318,528

     award amount
   • 5R01AG064244-03Department: NIH department code

     The Role of Synaptic Proteolysis in Alzheimer's Disease and Therapeutic Implications
     $557,275

     award amount
   • 5K01AG055694-05Department: NIH department code

     Receptor-mediated clearance of synaptic tau as a novel therapy for Alzheimer's disease.
     $124,551

     award amount

2. D'alessandro, Angelo

   Leads 1 award · $2,218,091

   • 5R01HL148151-03Department: NIH department code

     The Impact of Oxidative Stress on Erythocyte Biology
     $2,218,091

     award amount

3. Gu, Wei

   Leads 5 awards · $2,058,137

   • 1R35CA253059-01A1Department: NIH department code

     p53-mediated metabolic regulation in tumor suppression
     $570,812

     award amount
   • 5R01CA085533-17Department: NIH department code

     Regulation of p53 acetylation and deacetylation in tumorigenesis.
     $384,750

     award amount
   • 1R01CA254970-01Department: NIH department code

     Novel small molecule USP7 Inhibitors for p53 activation and cancer therapy
     $370,575

     award amount
   • 5R01CA216884-05Department: NIH department code

     Mechanisms of targeting oncoprotein SET in tumor suppression
     $366,000

     award amount
   • 5R01CA224272-04Department: NIH department code

     p53 acetylation in ferroptosis and tumor suppression
     $366,000

     award amount

4. Clelland, Catherine L

   Leads 1 award · $1,725,811

   • 1RF1AG069449-01A1Department: NIH department code

     Tetrahydrobiopterin Effects on Cognitive Function in Alzheimer's Disease: Biochemical, Molecular and Cognitive Analysis
     $1,725,811

     award amount

5. Pellizzoni, Livio

   Leads 3 awards · $1,463,029

   • 5R01NS114218-02Department: NIH department code

     Essential role of Stasimon in motor circuit development and disease
     $581,844

     award amount
   • 5R01NS116400-02Department: NIH department code

     Mechanisms and therapeutic targeting of motor neuron death in SMA
     $472,299

     award amount
   • 5R01NS102451-05Department: NIH department code

     RNA-Mediated Mechanisms of Motor System Dysfunction in Spinal Muscular Atrophy
     $408,886

     award amount

6. Gundersen, Gregg G

   Leads 3 awards · $1,426,251

   • 5R35GM136403-02Department: NIH department code

     Cytoskeleton, Nucleus and Integrin Recycling in Cell Migration
     $604,757

     award amount
   • 5R01AG064944-03Department: NIH department code

     Nucleoskeleton-Cytoskeleton Connections and Cell Polarity in Aging
     $416,494

     award amount
   • 3R01AG064944-03S1Department: NIH department code

     Nucleoskeleton-Cytoskeleton Connections and Cell Polarity in Aging
     $405,000

     award amount

7. Haeusler, Rebecca Anne

   Leads 2 awards · $1,189,580

   • 5R01DK115825-04Department: NIH department code

     Bile acids and insulin sensitivity
     $650,344

     award amount
   • 5R01HL125649-07Department: NIH department code

     Mechanisms linking insulin action with lipoprotein metabolism
     $539,236

     award amount

8. Mason, Carol A.

   Leads 3 awards · $1,073,953

   • 5R01EY015290-16Department: NIH department code

     Early retinal development in pigmented and albino mice: Factors in the CMZ and RPE controlling RGC specification
     $529,955

     award amount
   • 1R21NS122366-01Department: NIH department code

     Molecular mechanisms of glial-mediated synapse alterations in Fragile X syndrome
     $445,500

     award amount
   • 2T32EY013933-21Department: NIH department code

     Vision Sciences Training Grant
     $98,498

     award amount

9. Mentis, George Z

   Leads 2 awards · $1,066,152

   • 5R01AA027079-04Department: NIH department code

     Mechanisms of synaptic loss by the classical complement pathway in motor circuit development and disease
     $622,397

     award amount
   • 5R01NS078375-10Department: NIH department code

     Mechanisms of Central Synaptic Dysfunction in SMA
     $443,755

     award amount

10. Faust, Phyllis L

    Leads 1 award · $1,028,252

    • 1R01NS117745-01A1Department: NIH department code

      Deep Dive: Mapping the Neuropathology of Essential Tremor and Exploring the Molecular Underpinnings of Neurodegeneration
      $1,028,252

      award amount

11. Farber, Donna L.

    Leads 1 award · $999,932

    • 5U01AI150680-02Department: NIH department code

      Modeling the ecology of tissue-resident T cells
      $999,932

      award amount

12. Zeltser, Lori M

    Leads 2 awards · $988,104

    • 5R01DK125094-02Department: NIH department code

      Developmental programming of brown adipose tissue sympathetic tone
      $525,995

      award amount
    • 5R01MH113353-04Department: NIH department code

      Functional mapping of arginine vasopressin receptor 1A circuits that promote anorexic behavior
      $462,109

      award amount

13. Dalla-Favera, Riccardo

    Leads 1 award · $960,000

    • 5R35CA210105-06Department: NIH department code

      From pathogenesis to new therapeutic targets in Diffuse Large B cell Lymphoma
      $960,000

      award amount

14. Teich, Andrew Franklin

    Leads 2 awards · $910,912

    • 5R01AG059854-04Department: NIH department code

      A Translational Bioinformatics Approach to Rescuing Synaptic and Neurophysiologic Dysfunction in Alzheimer's Disease
      $506,404

      award amount
    • 3R01AG059854-04S1Department: NIH department code

      A Translational Bioinformatics Approach to Rescuing Synaptic and Neurophysiologic Dysfunction in Alzheimer's Disease
      $404,508

      award amount

15. Wichterle, Hynek

    Leads 2 awards · $901,124

    • 5R01NS109217-03Department: NIH department code

      Distal enhancers controlling motor neuron gene expression program
      $524,346

      award amount
    • 5R01NS116141-02Department: NIH department code

      Transcriptional Control of Motor Neuron Maturation
      $376,778

      award amount

16. McKhann, Guy M

    Leads 1 award · $809,998

    • 1R01AG073360-01Department: NIH department code

      An investigation of Alzheimer's Disease pathology, microglial immune response, and CSF proteomics in normal pressure hydrocephalus patients
      $809,998

      award amount

17. Siegelin, Markus D

    Leads 2 awards · $759,375

    • 1R01NS113793-01A1Department: NIH department code

      HDAC inhibitors reverse the Warburg Effect and Elicit Metabolic Vulnerabilities in Model Systems of Glioblastoma
      $405,000

      award amount
    • 5R01NS102366-04Department: NIH department code

      Targeting Mutant IDH1 for a Novel Synthetic Lethal Interaction in Malignant Gliomas
      $354,375

      award amount

18. Bartolini, Francesca

    Leads 1 award · $754,997

    • 2R56AG050658-06Department: NIH department code

      Pathogenic Roles for Microtubule Stabilization Pathways in Alzheimer's Disease
      $754,997

      award amount

19. Nuriel, Tal

    Leads 2 awards · $722,132

    • 1R01AG070202-01Department: NIH department code

      Elucidating the Temporal, Spatial and Cellular Effects of Differential APOE Isoform Expression
      $596,730

      award amount
    • 5K01AG061264-03Department: NIH department code

      Investigating the cause of APOE4-associated microglial activation and its resulting neurotoxicity of tauopathy-afflicted neurons
      $125,402

      award amount

20. Canman, Julie C

    Leads 2 awards · $683,934

    • 5R01GM117407-06Department: NIH department code

      Cell type-variation of cytokinesis
      $367,229

      award amount
    • 5R01GM130764-03Department: NIH department code

      Probing the spatiotemporal regulation of cell division
      $316,705

      award amount

21. Chung, Wendy K

    Leads 1 award · $654,299

    • 5R01NS114636-02Department: NIH department code

      Role of the Kinesin KIF1A in Neurological Disease
      $654,299

      award amount

22. Hussaini, S. Abid

    Leads 1 award · $622,966

    • 5R01AG064066-02Department: NIH department code

      Electrophysiological Evaluation of Brain Regions Vulnerable to Alzheimers Disease
      $622,966

      award amount

23. Gardner, Kevin L.

    Leads 1 award · $617,044

    • 5R01CA253368-02Department: NIH department code

      The linkage between Race, Kaiso and the tumor microenvironment in breast cancer health disparities
      $617,044

      award amount

24. Hod, Eldad Arie

    Leads 1 award · $590,148

    • 5R01HL139489-04Department: NIH department code

      Neurocognitive effects of iron deficiency in blood donors.
      $590,148

      award amount

25. Liem, Ronald K

    Leads 1 award · $546,154

    • 5T32GM008224-35Department: NIH department code

      Training in Cellular, Molecular and Biomedical Studies
      $546,154

      award amount

26. Baer, Richard J

    Leads 1 award · $523,500

    • 5R01CA227450-03Department: NIH department code

      Restoring genome stability and tumor suppression in BRCA1 deficient cells
      $523,500

      award amount

27. Przedborski, Serge E

    Leads 1 award · $522,649

    • 5R01NS107442-04Department: NIH department code

      Mechanisms of Axon Pathology in ALS
      $522,649

      award amount

28. Hengst, Ulrich

    Leads 1 award · $520,140

    • 5R01NS109607-04Department: NIH department code

      A transcription factor complex specifically induced in neurodegeneration
      $520,140

      award amount

29. Kim, Tae-Wan

    Leads 1 award · $509,123

    • 5R01AG067606-02Department: NIH department code

      Microglial TREM2 Interactome in Alzheimers Disease
      $509,123

      award amount

30. Yates, Andrew

    Leads 1 award · $504,481

    • 2R01AI093870-13A1Department: NIH department code

      Modeling the development, structure and regulation of T cell memory
      $504,481

      award amount

31. Pon, Liza A

    Leads 1 award · $489,973

    • 5R35GM122589-05Department: NIH department code

      Mitochondrial inheritance and quality control
      $489,973

      award amount

32. Su, Gloria Huei-Ting

    Leads 1 award · $480,016

    • 5R01CA217207-05Department: NIH department code

      The Development And Progression Of IPMN To PDA In The Context Of Inactivated Activin Signaling
      $480,016

      award amount

33. Waites, Clarissa Leigh

    Leads 1 award · $478,327

    • 5R01NS080967-08Department: NIH department code

      Uncovering the roles of ubiquitination and the ESCRT pathway in degradative sorting of SV proteins.
      $478,327

      award amount

34. Gershon, Michael D

    Leads 1 award · $438,743

    • 5R01NS015547-38Department: NIH department code

      MICROENVIRONMENT IN ENTERIC NEURON DEVELOPMENT
      $438,743

      award amount

35. McIntire, Laura Beth Johnson

    Leads 2 awards · $414,581

    • 1R56AG072794-01Department: NIH department code

      Acyl chain remodeling and regional lipid dysregulation in Alzheimer's disease
      $405,000

      award amount
    • 1R01AG072794-01A1Department: NIH department code

      Acyl chain remodeling and regional lipid dysregulation in Alzheimer's disease
      $9,581

      award amount

36. Choi, Eunhee

    Leads 1 award · $405,000

    • 1R35GM142937-01Department: NIH department code

      Investigation of the role of insulin receptor in chromosome stability.
      $405,000

      award amount

37. Au, Edmund

    Leads 1 award · $400,441

    • 1R01NS117695-01A1Department: NIH department code

      Studying the Molecular Regulation of MGE Projection Neuron Identity by St18
      $400,441

      award amount

38. Qiang, Li

    Leads 1 award · $400,000

    • 5R01DK112943-04Department: NIH department code

      PPARgamma Deacetylation in the Restoration of Metabolic Homeostasis
      $400,000

      award amount

39. Monani, Umrao

    Leads 1 award · $396,648

    • 5R01NS104218-03Department: NIH department code

      Spinal muscular atrophy: Mechanisms & treatment strategies.
      $396,648

      award amount

40. Greene, Lloyd A

    Leads 1 award · $391,387

    • 5R01NS072050-09Department: NIH department code

      Neuron death in Parkinson's disease: The role of Trib3
      $391,387

      award amount

41. Arancio, Ottavio

    Leads 1 award · $386,009

    • 5R01NS110024-03Department: NIH department code

      The role of SUMOylation in Tau-mediated pathology
      $386,009

      award amount

42. Pasqualucci, Laura

    Leads 1 award · $384,750

    • 5R01CA172492-09Department: NIH department code

      Role of KMT2D Gene Inactivation in B cell Non Hodgkin Lymphoma
      $384,750

      award amount

43. Dalerba, Piero D

    Leads 1 award · $380,419

    • 5R01DE028961-03Department: NIH department code

      Dissecting cell composition and drug sensitivity in human adenoid cystic carcinomas (ACCs).
      $380,419

      award amount

44. Israely, Inbal

    Leads 1 award · $376,532

    • 5R01NS112485-02Department: NIH department code

      Understanding how activity drives diverse spine structural interactions
      $376,532

      award amount

45. Acharyya, Swarnali

    Leads 1 award · $370,575

    • 5R01CA231239-03Department: NIH department code

      Modulating dietary zinc to prevent cachexia and improve survival in cancer
      $370,575

      award amount

46. Palomero, Teresa

    Leads 1 award · $370,575

    • 1R01CA256341-01A1Department: NIH department code

      Role and Mechanisms of VAV1 alterations in Peripheral T-cell Lymphomas
      $370,575

      award amount

47. Hudson, Krystalyn E

    Leads 1 award · $364,500

    • 5R01HL135248-05Department: NIH department code

      Regulation of RBC Alloimmunization by Naturally Occurring and Adaptive Antibodies
      $364,500

      award amount

48. Vallee, Richard Bert

    Leads 1 award · $357,343

    • 5R01GM132478-02Department: NIH department code

      Role of RILP in Autophagy
      $357,343

      award amount

49. Bruce, Jeffrey N

    Leads 1 award · $348,948

    • 5R01NS103473-05Department: NIH department code

      Single cell analysis of the infiltrative margins of glioblastoma and post-treatment recurrence
      $348,948

      award amount

50. Ghabrial, Amin S

    Leads 1 award · $335,807

    • 5R01GM089782-12Department: NIH department code

      Competition and morphogenesis in tip cell-mediated branching of tubular networks
      $335,807

      award amount

51. Coley, Shana M.

    Leads 1 award · $266,691

    • 1R21AI151491-01A1Department: NIH department code

      Predictive biomarkers of treatment response in kidney transplant rejection
      $266,691

      award amount

52. Shelanski, Michael L

    Leads 1 award · $243,000

    • 5R21AG063012-02Department: NIH department code

      Targeting Caspase-2 in Alzheimer's Disease
      $243,000

      award amount

53. Guo, Jia

    Leads 1 award · $202,500

    • 1R21AG074308-01Department: NIH department code

      Investigating the Effects of APOE Genotype on AD Pathology in a Novel AD Mouse Model
      $202,500

      award amount

54. Hargus, Gunnar

    Leads 1 award · $193,536

    • 1K08NS116166-01A1Department: NIH department code

      Elucidating the role of microglia and neurotrophin receptor p75 on neuronal degeneration in frontotemporal dementia
      $193,536

      award amount

55. Wontakal, Sandeep Nagaraj

    Leads 1 award · $193,536

    • 1K08NS119567-01Department: NIH department code

      Elucidating the Spatiotemporal Regulation of a Long Non-Coding RNA Required for Neurodevelopment
      $193,536

      award amount

56. Min, Jaewon

    Leads 1 award · $192,456

    • 1K22CA245259-01A1Department: NIH department code

      Anti-cancer therapeutic approaches for targeting the ALT telomere maintenance mechanism
      $192,456

      award amount

57. Weisberg, Stuart P

    Leads 1 award · $165,456

    • 5K08DK122130-03Department: NIH department code

      Tissue Resident Immune Cells in Human Pancreas.
      $165,456

      award amount

58. Patel, Tulsi

    Leads 1 award · $136,242

    • 1K99NS121136-01A1Department: NIH department code

      Defining motor neuron diversity from embryo to adulthood and generating tools for in vivo and in vitro access
      $136,242

      award amount

59. Rodriguez, Gustavo A

    Leads 1 award · $106,388

    • 5K01AG068598-02Department: NIH department code

      Impaired spatial decoding and neural population code rescaling in AD mice
      $106,388

      award amount

60. Chavez, Alejandro

    Leads 1 award · $69,571

    • 1R21HG011855-01Department: NIH department code

      Protein tagging at scale to enable functional genomic studies
      $69,571

      award amount

61. Colón Ortiz, Crystal K

    Leads 1 award · $47,036

    • 1F99NS124180-01A1Department: NIH department code

      Vascular-Glial Signaling in Neurovascular Injury
      $47,036

      award amount

62. Goldberg, Alexander

    Leads 1 award · $46,060

    • 1F30CA257768-01Department: NIH department code

      Targeting Neuron-Microglia Interactions at the Margin of Glioma
      $46,060

      award amount

63. Shih, Bobby Ben

    Leads 1 award · $46,036

    • 1F31CA261153-01Department: NIH department code

      Mechanism of Transformation in T-Cell Lymphomas: Identification of Therapeutic Targets
      $46,036

      award amount