Physiology at Columbia University

Leads a grant in this department

19 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Andrew Robert Marks

   Leads 4 awards · $5,828,511

   • 1RF1AG090466-01A1Department: NIH department code

     Neuronal Ryanodine Receptor Type 2: A Pivotal Player in Unraveling the Pathophysiology of Cardiogenic Cognitive Impairment
     $2,409,629

     award amount
   • 5P01HL164319-04Department: NIH department code

     Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

     Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

     $2,348,967

     award amount
   • 5R01HL178501-02Department: NIH department code

     Deciphering Statin-Induced Muscle Symptoms: Mechanisms and Therapeutic Insights
     $641,300

     award amount
   • 5R01GM147902-04Department: NIH department code

     Regulation of OXPHOS Assembly in Skeletal Muscles
     $428,615

     award amount

2. Stavroula Kousteni

   Leads 3 awards · $3,910,118

   • 5P01CA285250-03Department: NIH department code

     Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation

     Principal investigators: Emmanuelle Passegue (contact PI), Raul Rabadan (contact PI), Stavroula Kousteni (contact PI), Ulrich Steidl (contact PI)

     $2,743,615

     award amount
   • 5R01AG083081-03Department: NIH department code

     Epigenetic deregulation of osteoblasts promotes age related clonality in hematopoietic cells 
     $666,503

     award amount
   • 5R01AG080142-04Department: NIH department code

     Molecular Mechanisms of MDS pathogenesis with aging
     $500,000

     award amount

3. Henry M. Colecraft

   Leads 3 awards · $3,778,846

   • 5P01HL164319-04Department: NIH department code

     Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

     Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

     $2,348,967

     award amount
   • 5R01HL121253-12Department: NIH department code

     L-type channel trafficking and modulation in heart

     Principal investigators: Henry M. Colecraft (contact PI), Steven O Marx

     $798,406

     award amount
   • 5R01NS126850-05Department: NIH department code

     Towards Novel Therapies for CACNA1A Neurological Disorders
     $631,473

     award amount

4. Manu Ben Johny

   Leads 3 awards · $3,479,858

   • 5P01HL164319-04Department: NIH department code

     Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

     Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

     $2,348,967

     award amount
   • 1R01NS140214-01A1Department: NIH department code

     Targeted Depalmitoylation of Presynaptic CaV channels in Health and Disease
     $589,156

     award amount
   • 5R01HL163576-04Department: NIH department code

     Mechanism-inspired Strategies to Prevent Pathogenic Late Na Current in Cardiac Arrhythmias
     $541,735

     award amount

5. Emmanuelle Passegue

   Leads 1 award · $2,743,615

   • 5P01CA285250-03Department: NIH department code

     Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation

     Principal investigators: Emmanuelle Passegue (contact PI), Raul Rabadan (contact PI), Stavroula Kousteni (contact PI), Ulrich Steidl (contact PI)

     $2,743,615

     award amount

6. Raul Rabadan

   Leads 1 award · $2,743,615

   • 5P01CA285250-03Department: NIH department code

     Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation

     Principal investigators: Emmanuelle Passegue (contact PI), Raul Rabadan (contact PI), Stavroula Kousteni (contact PI), Ulrich Steidl (contact PI)

     $2,743,615

     award amount

7. Ulrich Steidl

   Leads 1 award · $2,743,615

   • 5P01CA285250-03Department: NIH department code

     Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation

     Principal investigators: Emmanuelle Passegue (contact PI), Raul Rabadan (contact PI), Stavroula Kousteni (contact PI), Ulrich Steidl (contact PI)

     $2,743,615

     award amount

8. Filippo Mancia

   Leads 4 awards · $2,401,810

   • 5R01AI147628-07Department: NIH department code

     Leveraging PfCRT Structure to Discern Function and Predict Emergence of Drug-Resistant Malaria

     Principal investigators: Filippo Mancia (contact PI), David A Fidock, Matthias Quick

     $817,959

     award amount
   • 5R01EY027405-08Department: NIH department code

     Structural basis of receptor-mediated cellular vitamin A uptake

     Principal investigators: Filippo Mancia (contact PI), George Khelashvili

     $606,079

     award amount
   • 5R01CA275005-04Department: NIH department code

     Molecular Mechanisms of Wnt Transport

     Principal investigators: Filippo Mancia (contact PI), David M Virshup

     $508,715

     award amount
   • 5R35GM132120-08Department: NIH department code

     Structural basis of integral membrane enzyme function
     $469,057

     award amount

9. Danish Saleheen

   Leads 1 award · $2,348,967

   • 5P01HL164319-04Department: NIH department code

     Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

     Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

     $2,348,967

     award amount

10. Emily J Tsai

    Leads 1 award · $2,348,967

    • 5P01HL164319-04Department: NIH department code

      Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

      Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

      $2,348,967

      award amount

11. Steven O Marx

    Leads 1 award · $2,348,967

    • 5P01HL164319-04Department: NIH department code

      Structure-Function of Calcium Channel Complexes in Cardiac Physiology and Disease

      Principal investigators: Andrew Robert Marks (contact PI), Danish Saleheen (contact PI), Emily J Tsai (contact PI), Henry M. Colecraft (contact PI), Manu Ben Johny (contact PI), Steven O Marx (contact PI)

      $2,348,967

      award amount

    Also a principal investigator on 5R01HL121253-12, led by Henry M. Colecraft.

12. Sabrina Diano

    Leads 2 awards · $1,533,612

    • 1R01DK144741-01A1Department: NIH department code

      Nutrient sensing in POMC neurons
      $838,425

      award amount
    • 5R01DK136079-04Department: NIH department code

      Hypothalamic lipid signaling in metabolism regulation
      $695,187

      award amount

13. X. Shawn Liu

    Leads 2 awards · $1,178,239

    • 5R01MH134519-04Department: NIH department code

      MeCP2 reactivation from the inactive X chromosome as treatment for Rett syndrome

      Principal investigators: X. Shawn Liu (contact PI), Antonio Bedalov

      $772,652

      award amount
    • 5R01NS126185-05Department: NIH department code

      Epigenetic Mechanisms Contributing to the Pathogenesis of ALS/FTD with GGGGCC Repeat Expansion Mutation at the C9orf72 Locus
      $405,587

      award amount

14. Sergei Doulatov

    Leads 2 awards · $1,163,245

    • 5R01HL151651-07Department: NIH department code

      Functional and molecular consequences of SF3B1 mutations in human hematopoietic stem cells

      Principal investigators: Sergei Doulatov (contact PI), Robert K Bradley

      $680,407

      award amount
    • 5R01HL169156-04Department: NIH department code

      The role of lamin B1 in normal and myelodysplastic hematopoiesis
      $482,838

      award amount

15. Wesley B Grueber

    Leads 2 awards · $358,884

    • 5R25NS130961-04Department: NIH department code

      CADRE Program for Postbaccalaureate Training in the Neurosciences

      Principal investigators: Wesley B Grueber (contact PI), Ulrich Hengst

      $223,884

      award amount
    • 5R25NS076445-14Department: NIH department code

      Summer Program for Undergraduate Rising Stars (SPURS), a Columbia University biomedical sciences pipeline program

      Principal investigators: Wesley B Grueber (contact PI), Steven A Siegelbaum

      $135,000

      award amount

16. Sri Karthika Shanmugam

    Leads 1 award · $133,436

    • 5K99HL177343-02Department: NIH department code

      Discerning L-type trafficking modulation by targeted excision of ubiquitin and SUMO
      $133,436

      award amount

17. Richard Li Cheng Pan

    Leads 1 award · $55,114

    • 5F30HD115371-03Department: NIH department code

      Epigenetic and Neuronal Mechanisms of MECP2 Reactivation to rescue Rett Syndrome
      $55,114

      award amount

18. Ryan Timothy Morgan

    Leads 1 award · $50,114

    • 5F31HD118755-02Department: NIH department code

      Molecular Basis of Lipid-linked Sugar Transfer
      $50,114

      award amount

19. Abby Wood

    Leads 1 award · $25,716

    • 5F31NS137735-03Department: NIH department code

      The Cellular and Neural Circuit Basis of Flexible Escape Behavior
      $25,716

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• David A Fidock

  Co-investigator on 5R01AI147628-07, led by Filippo Mancia

  From the FY2026 awards this person leads

  • Columbia University · Internal Medicine (NIH department code, 3 awards)

• Matthias Quick

  Co-investigator on 5R01AI147628-07, led by Filippo Mancia

  From the FY2026 awards this person leads

  • Columbia University · Psychiatry (NIH department code, 2 awards)

• Antonio Bedalov

  Co-investigator on 5R01MH134519-04, led by X. Shawn Liu

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Robert K Bradley

  Co-investigator on 5R01HL151651-07, led by Sergei Doulatov

  From the FY2026 awards this person leads

  • Fred Hutchinson Cancer Center (no department on record, 2 awards)

• George Khelashvili

  Co-investigator on 5R01EY027405-08, led by Filippo Mancia

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• David M Virshup

  Co-investigator on 5R01CA275005-04, led by Filippo Mancia

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Ulrich Hengst

  Co-investigator on 5R25NS130961-04, led by Wesley B Grueber

  From the FY2026 awards this person leads

  • Columbia University · Neurology (NIH department code, 1 award)
  • Columbia University · Pathology (NIH department code, 2 awards)

• Steven A Siegelbaum

  Co-investigator on 5R25NS076445-14, led by Wesley B Grueber

  From the FY2026 awards this person leads

  • Columbia University · Neurosciences (NIH department code, 3 awards)