Genetics at Icahn School of Medicine at Mount Sinai

Leads a grant in this department

45 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Cai, Dongming

   Leads 1 award · $3,641,905

   • 1RF1AG074010-01Department: NIH department code

     Dissect the interplay between sex and APOE at the single cell level to uncover novel pathways, targets and therapeutics for Alzheimer's disease
     $3,641,905

     award amount

2. Brennand, Kristen Jennifer

   Leads 4 awards · $3,255,997

   • 1R01MH125579-01A1Department: NIH department code

     Resolving complex alternative splicing of psychiatric disease genes using single-cell approaches
     $872,931

     award amount
   • 5R01AG068030-02Department: NIH department code

     Novel Network Biology Approaches to Reposition FDA-approved Drugs for Alzheimer's Disease
     $847,487

     award amount
   • 5R01MH121074-03Department: NIH department code

     Cell-type-specific NRXN1alpha alternative splicing changes in psychiatric disease
     $789,905

     award amount
   • 1R56AG071291-01A1Department: NIH department code

     Critical assessment of DNA adenine methylation in brain cells from healthy aging and Alzheimer's disease
     $745,674

     award amount

3. Ehrlich, Michelle E

   Leads 3 awards · $3,229,503

   • 5U01AG046170-09Department: NIH department code

     Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's Disease
     $1,848,040

     award amount
   • 5R01AG057907-05Department: NIH department code

     Integrative Network Modeling of Cognitive Resilience to Alzheimer's Disease
     $1,211,963

     award amount
   • 3U01AG046170-08S1Department: NIH department code

     Identification and characterization of receptors targeting VGF-derived peptides.
     $169,500

     award amount

4. Cho, Judy H.

   Leads 3 awards · $2,684,819

   • 5U24DK062429-22Department: NIH department code

     Inflammatory Bowel Disease Genetics Consortium Data Coordinating Center
     $1,452,414

     award amount
   • 5R01DK123758-02Department: NIH department code

     Intestinal single cell analyses and population differences in innate immunity in Crohn's disease drive treatment response and clinical heterogeneity: towards Precision IBD
     $736,014

     award amount
   • 5U01DK062422-22Department: NIH department code

     Mount Sinai School of Medicine Inflammatory Bowel Disease Genetics Research Cente
     $496,391

     award amount

5. Gelb, Bruce D

   Leads 1 award · $2,016,562

   • 3U01HG009610-04S1Department: NIH department code

     Incorporating genomics into the clinical care of diverse NYC children
     $2,016,562

     award amount

6. Kovatch, Patricia

   Leads 1 award · $2,000,000

   • 1S10OD030463-01Department: NIH department code

     COVID and Translational Science supercomputer (CATS)
     $2,000,000

     award amount

7. Geschwind, Daniel H

   Leads 1 award · $1,892,819

   • 1U54NS123746-01Department: NIH department code

     Uncovering the genetic mechanisms of the Chromosome 17q21.31 Tau haplotype on neurodegeneration risk in FTD and PSP
     $1,892,819

     award amount

8. Haroutunian, Vahram

   Leads 2 awards · $1,851,592

   • 5R01AG065582-02Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $1,513,570

     award amount
   • 3R01AG065582-02S1Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $338,022

     award amount

9. Jabs, Ethylin Wang

   Leads 3 awards · $1,716,935

   • 5R01DE029322-02Department: NIH department code

     Transcriptome and Network Analysis of Cleft Palate
     $770,984

     award amount
   • 1R01DE029832-01A1Department: NIH department code

     Genetic, Tissue, and Anatomical Interactions in Mandibulofacial Dysmorphogenesis
     $755,836

     award amount
   • 5T32HD075735-09Department: NIH department code

     Interdisciplinary Training in Systems and Developmental Biology and Birth Defects
     $190,115

     award amount

10. Do, Ron

    Leads 3 awards · $1,607,085

    • 1R01HL155915-01Department: NIH department code

      Elucidating hereditary transthyretin-mediated heart failure risk using machine learning, polygenic risk and recall by genotype approaches in African ancestry individuals
      $770,230

      award amount
    • 5R01HL139865-04Department: NIH department code

      Resolving Causal Influences Among Correlated Risk Biomarkers for Coronary Artery Disease
      $423,750

      award amount
    • 5R35GM124836-05Department: NIH department code

      Towards an integrated map of causal connections for common, complex diseases
      $413,105

      award amount

11. Fang, Gang

    Leads 3 awards · $1,548,368

    • 1R01HG011095-01A1Department: NIH department code

      Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome
      $833,051

      award amount
    • 1R35GM139655-01Department: NIH department code

      High Resolution Characterization of Bacterial Epigenomes and Microbiome
      $662,721

      award amount
    • 3R35GM139655-01S1Department: NIH department code

      High Resolution Characterization of Bacterial Epigenomes and Microbiome
      $52,596

      award amount

12. Gumus, Zeynep Hulya

    Leads 1 award · $1,542,450

    • 1R33CA263705-01Department: NIH department code

      PRIMAVO: Interactive exploration of cancer patient precision immune monitoring data in clinical trials
      $1,542,450

      award amount

13. Balwani, Manisha

    Leads 1 award · $1,353,572

    • 5U54DK083909-13Department: NIH department code

      Porphyrias Consortium
      $1,353,572

      award amount

14. Faith, Jeremiah James

    Leads 2 awards · $1,281,150

    • 5R01DK112978-03Department: NIH department code

      The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
      $688,219

      award amount
    • 5R01DK124133-02Department: NIH department code

      Uncovering the rules of gut microbiome strain transmission
      $592,931

      award amount

15. Xu, Pin-Xian

    Leads 2 awards · $1,142,858

    • 2R01DC014718-06A1Department: NIH department code

      Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner ear
      $581,813

      award amount
    • 5R01DK064640-18Department: NIH department code

      Transcription factors in early kidney development
      $561,045

      award amount

16. Sharp, Andrew James

    Leads 4 awards · $1,043,910

    • 5R01NS105781-04Department: NIH department code

      Identification of novel pathogenic tandem repeat expansions using long read sequencing
      $624,063

      award amount
    • 1R03AG069975-01Department: NIH department code

      Investigating tandem repeat variation as a cause of Alzheimer's disease from exome sequencing data
      $167,763

      award amount
    • 1R03HD103782-01Department: NIH department code

      Analysis of pathogenic tandem repeat variation in Gabriella Miller Kids First pediatric cohorts
      $167,438

      award amount
    • 1R03MH126147-01A1Department: NIH department code

      Investigating tandem repeat expansions as a cause of schizophrenia
      $84,646

      award amount

17. Tsankov, Alexander Minchev

    Leads 2 awards · $966,398

    • 1R56HL157632-01Department: NIH department code

      Decoding the cellular mechanisms of COVID-19 severe disease susceptibility in patients with chronic respiratory disease
      $839,491

      award amount
    • 1R21HL156124-01A1Department: NIH department code

      Single-cell analysis of the lung immune microenvironment and cell-cell interactions across healthy and diseased patients
      $126,907

      award amount

18. Klein, Robert J.

    Leads 2 awards · $886,991

    • 1R01CA244948-01A1Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $736,992

      award amount
    • 3R01CA244948-01A1S1Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $149,999

      award amount

19. Goate, Alison M

    Leads 1 award · $852,908

    • 5U01AG058635-04Department: NIH department code

      Genomic approach to identification of microglial networks involved in Alzheimer disease risk
      $852,908

      award amount

20. Roussos, Panagiotis

    Leads 1 award · $851,306

    • 1R01MH125246-01Department: NIH department code

      Multiethnic genomic epigenomic and transcriptomic fine-mapping and functional validation analysis of schizophrenia and bipolar disorder risk loci
      $851,306

      award amount

21. Crane, Heidi M.

    Leads 1 award · $827,529

    • 5R01HG010649-03Department: NIH department code

      Pharmacogenomics and Systems Pharmacology Approaches to Toxicity, Tolerability, and Comorbidities Associated with Modern Antiretroviral Therapies
      $827,529

      award amount

22. Holmes, Greg Peter

    Leads 1 award · $774,000

    • 1R01DE030596-01A1Department: NIH department code

      Coronal Suture Development in Health and Disease
      $774,000

      award amount

23. Huckins, Laura Marianne

    Leads 1 award · $738,209

    • 5R01MH118278-03Department: NIH department code

      Predicting the multi-omic impact of psychiatric GWAS associations
      $738,209

      award amount

24. Brown, Brian D

    Leads 1 award · $723,980

    • 5R01AT011326-02Department: NIH department code

      Development of a platform for spatial functional genomics
      $723,980

      award amount

25. O'Reilly, Paul Francis

    Leads 1 award · $635,256

    • 5R01MH122866-02Department: NIH department code

      Next-generation, pathway-specific, polygenic risk scores
      $635,256

      award amount

26. Pandey, Gaurav

    Leads 1 award · $539,951

    • 1R01HG011407-01A1Department: NIH department code

      Integrating genomic and clinical data to predict disease phenotypes using heterogeneous ensembles
      $539,951

      award amount

27. Andreassen, Ole A

    Leads 1 award · $464,729

    • 1R01MH124839-01Department: NIH department code

      3/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact
      $464,729

      award amount

28. Charney, Alexander W

    Leads 1 award · $429,337

    • 5R01MH121923-03Department: NIH department code

      3/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders
      $429,337

      award amount

29. Desnick, Robert J

    Leads 1 award · $424,030

    • 5T32GM082773-14Department: NIH department code

      Research Training for Medical Geneticists at Mount Sinai School of Medicine
      $424,030

      award amount

30. Huang, Kuan-Lin

    Leads 1 award · $423,069

    • 5R35GM138113-02Department: NIH department code

      Integrative Approaches for Identifying Causal Gene-Cell Type Pairs of Complex Disease
      $423,069

      award amount

31. Schuchman, Edward H.

    Leads 1 award · $415,275

    • 5R37HD028607-30Department: NIH department code

      Acid Sphingomyelinase and Niemann-Pick Disease
      $415,275

      award amount

32. Song, Won-Min

    Leads 1 award · $414,863

    • 1R35GM142918-01Department: NIH department code

      Integrative network modeling of bulk and single-cell sequencing data to characterize multi-scale cell architecture
      $414,863

      award amount

33. Devita, Robert J

    Leads 2 awards · $380,991

    • 1R21HD102745-01A1Department: NIH department code

      Substrate reduction as a novel therapeutic strategy for Glutaric Aciduria Type 1
      $296,407

      award amount
    • 1R03HD105916-01Department: NIH department code

      A novel treatment option for disorders of propionate metabolism
      $84,584

      award amount

34. Tu, Zhidong

    Leads 1 award · $370,700

    • 5R01AG055501-04Department: NIH department code

      Human tissue specific age-related gene expression changes, their genetic regulations and the link to human diseases
      $370,700

      award amount

35. Itan, Yuval

    Leads 1 award · $339,000

    • 5R01DK123530-03Department: NIH department code

      Identifying population-specific IBD-associated mutations, genes and pathways
      $339,000

      award amount

36. Clemente, Jose C

    Leads 1 award · $253,875

    • 1R21DK125906-01A1Department: NIH department code

      Effect of Maternal IBD, Microbiome and Early Life Events on the Bacterial Colonization and Mucosal Immunity in the Offspring
      $253,875

      award amount

37. Hopkins, Benjamin D.

    Leads 1 award · $220,218

    • 5R00CA230384-04Department: NIH department code

      Utilizing Precision Medicine to elucidate the mechanisms underpinning treatment efficacy
      $220,218

      award amount

38. Forst, Christian

    Leads 1 award · $211,875

    • 5R21AI149013-02Department: NIH department code

      Multi-scale analysis of single cell sequencing data to dissect the complexity of influenza infections
      $211,875

      award amount

39. Tyler, Scott R

    Leads 1 award · $143,146

    • 5K99HG011270-02Department: NIH department code

      Cross-Feature Correlations Define Cell Types, Asymmetric Cell Division, and Variant Networks
      $143,146

      award amount

40. Mollaoglu, Gurkan

    Leads 1 award · $95,308

    • 5K00CA223015-05Department: NIH department code

      Identifying Genetic Drivers of the Immunosuppressive Tumor Microenvironment in Lung Cancer
      $95,308

      award amount

41. Horgusluoglu-Moloch, Emrin

    Leads 1 award · $70,617

    • 5F32AG064904-02Department: NIH department code

      Systems Modeling of White Matter Microstructural Abnormalities in Alzheimer's Disease
      $70,617

      award amount

42. Neuner, Sarah M

    Leads 1 award · $65,994

    • 5F32AG069503-02Department: NIH department code

      Using human iPSC-derived microglia to understand the biological function of Alzheimer's risk variants
      $65,994

      award amount

43. Spindler, Matthew Paul

    Leads 1 award · $48,895

    • 1F30DK124978-01A1Department: NIH department code

      Influence of gut microbiota strain variation on mucosal T-cell phenotype
      $48,895

      award amount

44. Levantovsky, Rachel

    Leads 1 award · $45,876

    • 1F30DK127736-01A1Department: NIH department code

      Defining mechanisms of perianal fistula inception in African and European ancestry Crohn's disease patients
      $45,876

      award amount

45. Charytonowicz, Daniel

    Leads 1 award · $45,636

    • 1F30CA265288-01Department: NIH department code

      Defining and targeting the lung cancer progenitor cell niche using a high-resolution, multi-omics approach
      $45,636

      award amount