Genetics at Icahn School of Medicine at Mount Sinai

Leads a grant in this department

36 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Supinda Bunyavanich

   Leads 1 award · $3,399,999

   • 5UM1AI173380-02Department: NIH department code

     Systems Biology of Early Atopy (SUNBEAM) Analysis and Bioinformatics Center
     $3,399,999

     award amount

2. Bin Zhang

   Leads 3 awards · $2,903,939

   • 4R01AG074010-02Department: NIH department code

     Dissect the interplay between sex and APOE at the single cell level to uncover novel pathways, targets and therapeutics for Alzheimer's disease

     Principal investigators: Bin Zhang (contact PI), Dongming Cai

     $1,217,104

     award amount
   • 5R01AG068030-05Department: NIH department code

     Novel Network Biology Approaches to Reposition FDA-approved Drugs for Alzheimer's Disease

     Principal investigators: Bin Zhang (contact PI), Dongming Cai, Kristen Jennifer Brennand

     $844,721

     award amount
   • 1R01AG085182-01A1Department: NIH department code

     Identification and Characterization of Senescent Cells in Molecular Subtypes of Alzheimer's Disease

     Principal investigators: Bin Zhang (contact PI), Miranda Ethel Orr

     $842,114

     award amount

3. Panagiotis Roussos

   Leads 1 award · $2,188,178

   • 5R01AG082185-02Department: NIH department code

     The adaptive-innate immune interactome across multiple tissues in Alzheimer's disease

     Principal investigators: Panagiotis Roussos (contact PI), Cameron Stuart McAlpine, Donghoon Lee, Vahram Haroutunian

     $2,188,178

     award amount

4. Gang Fang

   Leads 2 awards · $1,667,681

   • 5R01MH125579-04Department: NIH department code

     Resolving complex alternative splicing of psychiatric disease genes using single-cell approaches

     Principal investigators: Gang Fang (contact PI), Kristen Jennifer Brennand

     $841,691

     award amount
   • 5R35GM139655-04Department: NIH department code

     High Resolution Characterization of Bacterial Epigenomes and Microbiome
     $825,990

     award amount

5. Jeremiah James Faith

   Leads 4 awards · $1,618,251

   • 5R01DK112978-06Department: NIH department code

     The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
     $626,381

     award amount
   • 2R01DK124133-05Department: NIH department code

     Uncovering the rules of gut microbiome strain transmission
     $617,193

     award amount
   • 5R01DK130337-03Department: NIH department code

     Comparison of defined live biotherapeutic product and fecal microbiota transplantation for treatment of recurrent Clostridioides difficile infection

     Principal investigators: Jeremiah James Faith (contact PI), Ari Grinspan

     $324,480

     award amount
   • 3R01DK112978-06S1Department: NIH department code

     The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
     $50,197

     award amount

6. Ron Do

   Leads 3 awards · $1,429,077

   • 5R01HL155915-04Department: NIH department code

     Elucidating hereditary transthyretin-mediated heart failure risk using machine learning, polygenic risk and recall by genotype approaches in African ancestry individuals

     Principal investigators: Ron Do (contact PI), Girish Nitin Nadkarni

     $738,557

     award amount
   • 5R35GM124836-07Department: NIH department code

     Computational approaches to advance genomic, biological and clinical understandings of human disease
     $453,075

     award amount
   • 3R01HL155915-04S1Department: NIH department code

     Elucidating hereditary transthyretin-mediated heart failure risk using machine learning, polygenic risk and recall by genotype approaches in African ancestry individuals

     Principal investigators: Ron Do (contact PI), Girish Nitin Nadkarni

     $237,445

     award amount

7. Yizhou Dong

   Leads 4 awards · $1,375,424

   • 5R01AI174902-02Department: NIH department code

     Integration of adjuvant derived nanoparticles and engineered mRNA for HIV vaccine discovery

     Principal investigators: Yizhou Dong (contact PI), Darrell J Irvine

     $751,497

     award amount
   • 5R35GM144117-04Department: NIH department code

     Construction of in vivo mRNA delivery systems
     $464,750

     award amount
   • 3R35GM144117-04S1Department: NIH department code

     Construction of in vivo mRNA delivery systems
     $96,459

     award amount
   • 3R01AI174902-02S1Department: NIH department code

     Integration of adjuvant derived nanoparticles and engineered mRNA for HIV vaccine discovery

     Principal investigators: Yizhou Dong (contact PI), Darrell J Irvine

     $62,718

     award amount

8. Paul Francis O'Reilly

   Leads 2 awards · $1,277,970

   • 5R01HG012773-02Department: NIH department code

     BridgePRS: bridging the gap in polygenic risk scores between ancestries.
     $641,630

     award amount
   • 5R01MH122866-05Department: NIH department code

     Next-generation, pathway-specific, polygenic risk scores
     $636,340

     award amount

9. Brian D Brown

   Leads 2 awards · $1,270,303

   • 5R01AT011326-05Department: NIH department code

     Development of a platform for spatial functional genomics
     $711,098

     award amount
   • 1R01DK138025-01Department: NIH department code

     microRNA-controlled mRNA therapeutics
     $559,205

     award amount

10. Pin-Xian Xu

    Leads 2 awards · $1,244,596

    • 2R01DK064640-19A1Department: NIH department code

      Transcription factors in kidney development
      $663,643

      award amount
    • 5R01DC014718-09Department: NIH department code

      Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner ear
      $580,953

      award amount

11. Alison M Goate

    Leads 1 award · $1,191,261

    • 5R01AG072489-03Department: NIH department code

      Neuroprotective signaling and transcriptional pathways in microglia associated with Alzheimer's disease

      Principal investigators: Alison M Goate (contact PI), Alexander Tarakhovsky, Anne Schaefer

      $1,191,261

      award amount

12. Ernest Turro

    Leads 2 awards · $791,388

    • 5R01HL161365-02Department: NIH department code

      Integrative analysis of whole genomes and transcriptomes from multiple cell types in rare disease patients
      $622,388

      award amount
    • 5R03HD111492-02Department: NIH department code

      Bayesian genetic association analysis of all rare diseases in the Kids First cohort
      $169,000

      award amount

13. Pei Wang

    Leads 1 award · $787,902

    • 5U24CA271114-03Department: NIH department code

      Proteogenomic translator for cancer biomarker discovery towards precision medicine

      Principal investigators: Pei Wang (contact PI), Avi Ma'ayan

      $787,902

      award amount

14. Greg Peter Holmes

    Leads 1 award · $776,680

    • 5R01DE030596-04Department: NIH department code

      Coronal Suture Development in Health and Disease

      Principal investigators: Greg Peter Holmes (contact PI), Ethylin Wang Jabs, Harm Van Bakel

      $776,680

      award amount

15. Sander Michel Houten

    Leads 1 award · $718,385

    • 5R01HD112518-02Department: NIH department code

      Allosteric regulation of lysine degradation as a novel pathophysiological mechanism in glutaric aciduria type 1

      Principal investigators: Sander Michel Houten (contact PI), Michael Block Lazarus, Robert J Devita

      $718,385

      award amount

16. Christian Forst

    Leads 1 award · $637,256

    • 5R01AI170112-03Department: NIH department code

      Deciphering the Heterogeneous Response to Influenza by a Multi-Scale Systems Approach
      $637,256

      award amount

17. Mayte Suarez-Farinas

    Leads 1 award · $593,113

    • 5R01HG011407-04Department: NIH department code

      Integrating genomic and clinical data to predict disease phenotypes using heterogeneous ensembles
      $593,113

      award amount

18. Makiko Yasuda

    Leads 1 award · $579,510

    • 5R01DK134783-02Department: NIH department code

      Mechanisms of Intercellular Heme Homeostasis in Liver
      $579,510

      award amount

19. Vikas Rao Pejaver

    Leads 2 awards · $574,394

    • 1R03OD038386-01Department: NIH department code

      Variant impact prediction on Common Fund data sets towards drug repurposing for rare genetic diseases
      $338,000

      award amount
    • 5R00LM012992-05Department: NIH department code

      Integrative data science approaches for rare disease discovery in health records
      $236,394

      award amount

20. David Sachs

    Leads 1 award · $557,067

    • 1R01HL173456-01Department: NIH department code

      Microfluidic organoid model of cardio-hepatic physiology and disease
      $557,067

      award amount

21. Edward H. Schuchman

    Leads 1 award · $517,568

    • 5R01HD109312-03Department: NIH department code

      Endocannabinoid-Based Treatment for the Neurologic Niemann-Pick Diseases
      $517,568

      award amount

22. Jun Wang

    Leads 1 award · $464,750

    • 1R21AG085140-01Department: NIH department code

      Molecular mechanisms of pathological aging of human brain and adipose and their inter-organ communication
      $464,750

      award amount

23. Kuan-Lin Huang

    Leads 1 award · $423,069

    • 5R35GM138113-05Department: NIH department code

      Integrative Approaches for Identifying Causal Gene-Cell Type Pairs of Complex Disease
      $423,069

      award amount

24. Anna S Tocheva

    Leads 1 award · $422,500

    • 5R35GM150989-02Department: NIH department code

      Molecular mechanisms underlying T cell resistance to PD-1 signaling
      $422,500

      award amount

25. Won-Min Song

    Leads 1 award · $422,500

    • 5R35GM142918-04Department: NIH department code

      Integrative network modeling of bulk and single-cell sequencing data to characterize multi-scale cell architecture
      $422,500

      award amount

26. Inga Peter

    Leads 1 award · $383,980

    • 5R01DK130094-03Department: NIH department code

      Preclinical Validation of Novel Gut-Restricted LRRK2 Inhibitors as Therapeutic Leads for IBD

      Principal investigators: Inga Peter (contact PI), Robert J Devita

      $383,980

      award amount

27. Reymundo Lozano

    Leads 1 award · $281,242

    • 5K01NS126736-03Department: NIH department code

      FXTAS Key Molecular Pathways Converge with Other Neurodegenerative Disorders
      $281,242

      award amount

28. Robert J. Klein

    Leads 2 awards · $262,824

    • 5R01CA244948-04Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $158,706

      award amount
    • 3R01CA244948-04S1Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $104,118

      award amount

29. Chelsea Lowther

    Leads 1 award · $249,000

    • 4R00HD108392-03Department: NIH department code

      Disruption of three-dimensional genome organization as a noncoding mechanism of disease in human developmental disorders
      $249,000

      award amount

30. Wenyan Jiang

    Leads 1 award · $249,000

    • 5R00AI153530-04Department: NIH department code

      New CRISPR tools for systematic interrogation of genetic and transcriptional determinants of antibiotic sensitivity in bacteria
      $249,000

      award amount

31. Gita A Pathak

    Leads 1 award · $248,977

    • 4R00AG078503-03Department: NIH department code

      Multi-modal intersection of depression and genetic liability to Alzheimers disease
      $248,977

      award amount

32. Judit Garcia Gonzalez

    Leads 1 award · $151,956

    • 1K99HG013547-01Department: NIH department code

      PATHFINDER: Finding the genomic and clinical pathways underlying heterogeneity in complex disease
      $151,956

      award amount

33. Francesca Garretti

    Leads 1 award · $74,284

    • 5F32AG082483-02Department: NIH department code

      Investigating the role of an EIF2B3 variant as an Alzheimer's disease risk modifier
      $74,284

      award amount

34. Carina Seah

    Leads 1 award · $51,694

    • 5F30MH132324-02Department: NIH department code

      Modeling gene x environment interactions in post-traumatic stress disorder.
      $51,694

      award amount

35. Alexandra Munch

    Leads 1 award · $47,374

    • 5F31AG084337-02Department: NIH department code

      Uncovering the Role of the MS4A Gene Family in Alzheimer's Disease
      $47,374

      award amount

36. Kayla Retallick-Townsley

    Leads 1 award · $30,103

    • 5F31MH130122-03Department: NIH department code

      Massively Parallel Characterization of Cell-type and Context Specific Regulatory Risk Elements Across Psychiatric Disorders in a Stem Cell Model of Neurodevelopment
      $30,103

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Cameron Stuart McAlpine

  Co-investigator on 5R01AG082185-02, led by Panagiotis Roussos

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Internal Medicine (NIH department code, 1 award)

• Donghoon Lee

  Co-investigator on 5R01AG082185-02, led by Panagiotis Roussos

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Vahram Haroutunian

  Co-investigator on 5R01AG082185-02, led by Panagiotis Roussos

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Dongming Cai

  Co-investigator on 4R01AG074010-02, led by Bin Zhang; 5R01AG068030-05, led by Bin Zhang

  From the FY2024 awards this person leads

  • University of Minnesota · Neurology (NIH department code, 1 award)

• Kristen Jennifer Brennand

  Co-investigator on 5R01AG068030-05, led by Bin Zhang; 5R01MH125579-04, led by Gang Fang

  From the FY2024 awards this person leads

  • Yale University · Psychiatry (NIH department code, 2 awards)

• Alexander Tarakhovsky

  Co-investigator on 5R01AG072489-03, led by Alison M Goate

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Anne Schaefer

  Co-investigator on 5R01AG072489-03, led by Alison M Goate

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Neurosciences (NIH department code, 2 awards)
  • Icahn School of Medicine at Mount Sinai (no department on record, 2 awards)

• Robert J Devita

  Co-investigator on 5R01HD112518-02, led by Sander Michel Houten; 5R01DK130094-03, led by Inga Peter

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Girish Nitin Nadkarni

  Co-investigator on 5R01HL155915-04, led by Ron Do; 3R01HL155915-04S1, led by Ron Do

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Internal Medicine (NIH department code, 2 awards)

• Miranda Ethel Orr

  Co-investigator on 1R01AG085182-01A1, led by Bin Zhang

  From the FY2024 awards this person leads

  • Wake Forest University Health Sciences · Internal Medicine (NIH department code, 1 award)

• Darrell J Irvine

  Co-investigator on 5R01AI174902-02, led by Yizhou Dong; 3R01AI174902-02S1, led by Yizhou Dong

  From the FY2024 awards this person leads

  • Massachusetts Institute of Technology · Engineering (NIH department code, 4 awards)
  • Massachusetts Institute of Technology (no department on record, 1 award)

• Avi Ma'ayan

  Co-investigator on 5U24CA271114-03, led by Pei Wang

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Pharmacology (NIH department code, 3 awards)

• Ethylin Wang Jabs

  Co-investigator on 5R01DE030596-04, led by Greg Peter Holmes

  From the FY2024 awards this person leads

  • Mayo Clinic (no department on record, 2 awards)

• Harm Van Bakel

  Co-investigator on 5R01DE030596-04, led by Greg Peter Holmes

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai (no department on record, 1 award)

• Michael Block Lazarus

  Co-investigator on 5R01HD112518-02, led by Sander Michel Houten

  From the FY2024 awards this person leads

  • Icahn School of Medicine at Mount Sinai · Pharmacology (NIH department code, 1 award)

• Ari Grinspan

  Co-investigator on 5R01DK130337-03, led by Jeremiah James Faith

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.