Genetics at Icahn School of Medicine at Mount Sinai

Leads a grant in this department

48 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Brennand, Kristen Jennifer

   Leads 3 awards · $2,440,147

   • 5R01AG068030-03Department: NIH department code

     Novel Network Biology Approaches to Reposition FDA-approved Drugs for Alzheimer's Disease
     $847,014

     award amount
   • 5R01MH125579-02Department: NIH department code

     Resolving complex alternative splicing of psychiatric disease genes using single-cell approaches
     $809,669

     award amount
   • 5R01MH121074-04Department: NIH department code

     Cell-type-specific NRXN1alpha alternative splicing changes in psychiatric disease
     $783,464

     award amount

2. Finkbeiner, Steven M

   Leads 2 awards · $2,274,572

   • 5R01AG067025-04Department: NIH department code

     Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer Disease
     $1,833,217

     award amount
   • 3R01AG067025-04S1Department: NIH department code

     Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer Disease
     $441,355

     award amount

3. Ehrlich, Michelle E

   Leads 1 award · $2,272,422

   • 5U01AG046170-10Department: NIH department code

     Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's Disease
     $2,272,422

     award amount

4. Haroutunian, Vahram

   Leads 3 awards · $2,185,901

   • 5R01AG065582-03Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $1,513,570

     award amount
   • 3R01AG065582-03S1Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $422,331

     award amount
   • 3R01AG065582-03S2Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $250,000

     award amount

5. Goate, Alison M

   Leads 2 awards · $2,059,658

   • 1R01AG072489-01A1Department: NIH department code

     Neuroprotective signaling and transcriptional pathways in microglia associated with Alzheimer's disease
     $1,224,125

     award amount
   • 5U01AG058635-05Department: NIH department code

     Genomic approach to identification of microglial networks involved in Alzheimer disease risk
     $835,533

     award amount

6. Cho, Judy H.

   Leads 3 awards · $2,042,358

   • 2U24DK062429-23Department: NIH department code

     Precision IBD via genetics and genomics: integrating International and multi-omic datasets, expanding studies in diverse populations, and defining mechanisms of unmet clinical needs in IBD
     $1,210,619

     award amount
   • 5R01DK123758-03Department: NIH department code

     Intestinal single cell analyses and population differences in innate immunity in Crohn's disease drive treatment response and clinical heterogeneity: towards Precision IBD
     $736,014

     award amount
   • 2U01DK062422-23Department: NIH department code

     Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations
     $95,725

     award amount

7. Geschwind, Daniel H

   Leads 1 award · $1,834,889

   • 5U54NS123746-02Department: NIH department code

     Uncovering the genetic mechanisms of the Chromosome 17q21.31 Tau haplotype on neurodegeneration risk in FTD and PSP
     $1,834,889

     award amount

8. Fang, Gang

   Leads 3 awards · $1,802,257

   • 5R01HG011095-02Department: NIH department code

     Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome
     $876,312

     award amount
   • 5R35GM139655-02Department: NIH department code

     High Resolution Characterization of Bacterial Epigenomes and Microbiome
     $825,990

     award amount
   • 3R35GM139655-02S1Department: NIH department code

     High Resolution Characterization of Bacterial Epigenomes and Microbiome
     $99,955

     award amount

9. Jabs, Ethylin Wang

   Leads 3 awards · $1,698,789

   • 5R01DE029322-03Department: NIH department code

     Transcriptome and Network Analysis of Cleft Palate
     $760,374

     award amount
   • 5R01DE029832-02Department: NIH department code

     Genetic, Tissue, and Anatomical Interactions in Mandibulofacial Dysmorphogenesis
     $724,402

     award amount
   • 5T32HD075735-10Department: NIH department code

     Interdisciplinary Training in Systems and Developmental Biology and Birth Defects
     $214,013

     award amount

10. Faith, Jeremiah James

    Leads 3 awards · $1,619,150

    • 5R01DK112978-04Department: NIH department code

      The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
      $688,219

      award amount
    • 5R01DK124133-03Department: NIH department code

      Uncovering the rules of gut microbiome strain transmission
      $592,931

      award amount
    • 1R01DK130337-01A1Department: NIH department code

      Comparison of defined live biotherapeutic product and fecal microbiota transplantation for treatment of recurrent Clostridioides difficile infection
      $338,000

      award amount

11. Balwani, Manisha

    Leads 2 awards · $1,581,180

    • 5U54DK083909-14Department: NIH department code

      Porphyrias Consortium
      $1,349,667

      award amount
    • 3U54DK083909-14S1Department: NIH department code

      Administrative Supplemental for Porphyria Rare Disease Clinical Research Consortium (RDCRC)
      $231,513

      award amount

12. Akbarian, Schahram

    Leads 1 award · $1,172,284

    • 5U01MH116442-05Department: NIH department code

      The 3D genome in transcriptional regulation across the postnatal life span, with implications for schizophrenia and bipolar disorder
      $1,172,284

      award amount

13. Sharp, Andrew James

    Leads 4 awards · $1,044,806

    • 5R01NS105781-05Department: NIH department code

      Identification of novel pathogenic tandem repeat expansions using long read sequencing
      $622,306

      award amount
    • 5R03AG069975-02Department: NIH department code

      Investigating tandem repeat variation as a cause of Alzheimer's disease from exome sequencing data
      $169,000

      award amount
    • 5R03HD103782-02Department: NIH department code

      Analysis of pathogenic tandem repeat variation in Gabriella Miller Kids First pediatric cohorts
      $169,000

      award amount
    • 5R03MH126147-02Department: NIH department code

      Investigating tandem repeat expansions as a cause of schizophrenia
      $84,500

      award amount

14. Pandey, Gaurav

    Leads 2 awards · $1,033,964

    • 5R01HG011407-02Department: NIH department code

      Integrating genomic and clinical data to predict disease phenotypes using heterogeneous ensembles
      $535,451

      award amount
    • 1U01CA271318-01Department: NIH department code

      Multi-modal data integration to identify kinase substrates
      $498,513

      award amount

15. Holmes, Greg Peter

    Leads 2 awards · $882,943

    • 5R01DE030596-02Department: NIH department code

      Coronal Suture Development in Health and Disease
      $785,193

      award amount
    • 3R01DE030596-02S1Department: NIH department code

      Coronal Suture Development in Health and Disease
      $97,750

      award amount

16. Klein, Robert J.

    Leads 3 awards · $871,962

    • 5R01CA244948-02Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $694,737

      award amount
    • 3R01CA244948-02S2Department: NIH department code

      Genetic predictors of prostate cancer survival
      $109,052

      award amount
    • 3R01CA244948-02S1Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $68,173

      award amount

17. Ma'ayan, Avi

    Leads 1 award · $850,957

    • 1U24CA271114-01Department: NIH department code

      Proteogenomic translator for cancer biomarker discovery towards precision medicine
      $850,957

      award amount

18. Crane, Heidi M.

    Leads 1 award · $823,609

    • 5R01HG010649-04Department: NIH department code

      Pharmacogenomics and Systems Pharmacology Approaches to Toxicity, Tolerability, and Comorbidities Associated with Modern Antiretroviral Therapies
      $823,609

      award amount

19. Do, Ron

    Leads 1 award · $743,821

    • 5R01HL155915-02Department: NIH department code

      Elucidating hereditary transthyretin-mediated heart failure risk using machine learning, polygenic risk and recall by genotype approaches in African ancestry individuals
      $743,821

      award amount

20. Brown, Brian D

    Leads 1 award · $707,878

    • 5R01AT011326-03Department: NIH department code

      Development of a platform for spatial functional genomics
      $707,878

      award amount

21. Devita, Robert J

    Leads 3 awards · $653,478

    • 1R01DK130094-01A1Department: NIH department code

      Preclinical Validation of Novel Gut-Restricted LRRK2 Inhibitors as Therapeutic Leads for IBD
      $399,978

      award amount
    • 5R21HD102745-02Department: NIH department code

      Substrate reduction as a novel therapeutic strategy for Glutaric Aciduria Type 1
      $169,000

      award amount
    • 5R03HD105916-02Department: NIH department code

      A novel treatment option for disorders of propionate metabolism
      $84,500

      award amount

22. O'Reilly, Paul Francis

    Leads 1 award · $636,340

    • 5R01MH122866-03Department: NIH department code

      Next-generation, pathway-specific, polygenic risk scores
      $636,340

      award amount

23. Forst, Christian

    Leads 1 award · $619,606

    • 1R01AI170112-01Department: NIH department code

      Deciphering the Heterogeneous Response to Influenza by a Multi-Scale Systems Approach
      $619,606

      award amount

24. Xu, Pin-Xian

    Leads 1 award · $580,953

    • 5R01DC014718-07Department: NIH department code

      Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner ear
      $580,953

      award amount

25. Schuchman, Edward H.

    Leads 1 award · $540,046

    • 1R01HD109312-01Department: NIH department code

      Endocannabinoid-Based Treatment for the Neurologic Niemann-Pick Diseases
      $540,046

      award amount

26. Li, Aiqun

    Leads 1 award · $464,750

    • 1R21AG077168-01Department: NIH department code

      Systematic identification of genetic modifiers of dysfunctional neuronal networks in Alzheimer's disease
      $464,750

      award amount

27. Dogra, Navneet

    Leads 1 award · $463,991

    • 1R21AG078848-01Department: NIH department code

      Delineating the RNA cargo of exosomes from brain microenvironment
      $463,991

      award amount

28. Desnick, Robert J

    Leads 1 award · $439,209

    • 5T32GM082773-15Department: NIH department code

      Research Training for Medical Geneticists at Mount Sinai School of Medicine
      $439,209

      award amount

29. Charney, Alexander W

    Leads 1 award · $429,337

    • 5R01MH121923-04Department: NIH department code

      3/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders
      $429,337

      award amount

30. Huang, Kuan-Lin

    Leads 1 award · $423,069

    • 5R35GM138113-03Department: NIH department code

      Integrative Approaches for Identifying Causal Gene-Cell Type Pairs of Complex Disease
      $423,069

      award amount

31. Song, Won-Min

    Leads 1 award · $422,500

    • 5R35GM142918-02Department: NIH department code

      Integrative network modeling of bulk and single-cell sequencing data to characterize multi-scale cell architecture
      $422,500

      award amount

32. Wang, Minghui

    Leads 1 award · $419,201

    • 3U01AG046170-09S1Department: NIH department code

      Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's Disease
      $419,201

      award amount

33. Tu, Zhidong

    Leads 1 award · $370,700

    • 5R01AG055501-05Department: NIH department code

      Human tissue specific age-related gene expression changes, their genetic regulations and the link to human diseases
      $370,700

      award amount

34. Ioannou, Yiannis A

    Leads 1 award · $295,531

    • 1R21HD108675-01A1Department: NIH department code

      Targeting the lysosome-mitochondria axis in neurodegenerative lysosomal storage diseases - Lessons from telomerase immortalization
      $295,531

      award amount

35. Lozano, Reymundo

    Leads 1 award · $270,915

    • 1K01NS126736-01Department: NIH department code

      FXTAS Key Molecular Pathways Converge with Other Neurodegenerative Disorders
      $270,915

      award amount

36. Liu, Bian

    Leads 1 award · $253,500

    • 1R21DK131555-01Department: NIH department code

      Development of a Simple Youth Diabetes Screening Tool Using Machine Learning
      $253,500

      award amount

37. Tsankov, Alexander Minchev

    Leads 2 awards · $253,500

    • 1R21HL161760-01Department: NIH department code

      Comparative, single-cell analysis of COVID-19 and other respiratory diseases
      $126,750

      award amount
    • 5R21HL156124-02Department: NIH department code

      Single-cell analysis of the lung immune microenvironment and cell-cell interactions across healthy and diseased patients
      $126,750

      award amount

38. Pejaver, Vikas Rao

    Leads 1 award · $235,929

    • 4R00LM012992-03Department: NIH department code

      Integrative data science approaches for rare disease discovery in health records
      $235,929

      award amount

39. Dong, Yizhou

    Leads 1 award · $223,497

    • 7R35GM144117-02Department: NIH department code

      Construction of in vivo mRNA delivery systems
      $223,497

      award amount

40. Clemente, Jose C

    Leads 1 award · $211,250

    • 5R21DK125906-02Department: NIH department code

      Effect of Maternal IBD, Microbiome and Early Life Events on the Bacterial Colonization and Mucosal Immunity in the Offspring
      $211,250

      award amount

41. Tyler, Scott R

    Leads 1 award · $108,669

    • 3K99HG011270-02S1Department: NIH department code

      Cross-Feature Correlations Define Cell Types, Asymmetric Cell Division, and Variant Networks
      $108,669

      award amount

42. Mollaoglu, Gurkan

    Leads 1 award · $99,870

    • 5K00CA223015-06Department: NIH department code

      Identifying Genetic Drivers of the Immunosuppressive Tumor Microenvironment in Lung Cancer
      $99,870

      award amount

43. Whitney, Kristen

    Leads 1 award · $72,082

    • 1F32AG072837-01A1Department: NIH department code

      The role of astrocytes in the pathogenesis of sporadic tauopathy
      $72,082

      award amount

44. Neuner, Sarah M

    Leads 1 award · $67,582

    • 5F32AG069503-03Department: NIH department code

      Using human iPSC-derived microglia to understand the biological function of Alzheimer's risk variants
      $67,582

      award amount

45. Retallick-Townsley, Kayla

    Leads 1 award · $46,592

    • 1F31MH130122-01Department: NIH department code

      Massively Parallel Characterization of Cell-type and Context Specific Regulatory Risk Elements Across Psychiatric Disorders in a Stem Cell Model of Neurodevelopment
      $46,592

      award amount

46. Charytonowicz, Daniel

    Leads 1 award · $45,152

    • 5F30CA265288-02Department: NIH department code

      Defining and targeting the lung cancer progenitor cell niche using a high-resolution, multi-omics approach
      $45,152

      award amount

47. Levantovsky, Rachel

    Leads 1 award · $45,152

    • 5F30DK127736-02Department: NIH department code

      Defining mechanisms of perianal fistula inception in African and European ancestry Crohn's disease patients
      $45,152

      award amount

48. Spindler, Matthew Paul

    Leads 1 award · $36,376

    • 5F30DK124978-02Department: NIH department code

      Influence of gut microbiota strain variation on mucosal T-cell phenotype
      $36,376

      award amount