Genetics at Icahn School of Medicine at Mount Sinai

Leads a grant in this department

44 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Haroutunian, Vahram

   Leads 2 awards · $4,374,079

   • 1R01AG082185-01Department: NIH department code

     The adaptive-innate immune interactome across multiple tissues in Alzheimer's disease
     $2,438,178

     award amount
   • 5R01AG065582-04Department: NIH department code

     Understanding the protective and neuroinflammatory role of human brain immune cells in Alzheimer Disease
     $1,935,901

     award amount

2. Bunyavanich, Supinda

   Leads 1 award · $3,649,933

   • 1UM1AI173380-01Department: NIH department code

     Systems Biology of Early Atopy (SUNBEAM) Analysis and Bioinformatics Center
     $3,649,933

     award amount

3. Roussos, Panagiotis

   Leads 1 award · $2,576,654

   • 1RF1MH133703-01Department: NIH department code

     Towards an integrated analytics solution to creating a spatially-resolved single-cell multi-omics brain atlas
     $2,576,654

     award amount

4. Brennand, Kristen Jennifer

   Leads 3 awards · $2,344,916

   • 5R01AG068030-04Department: NIH department code

     Novel Network Biology Approaches to Reposition FDA-approved Drugs for Alzheimer's Disease
     $846,972

     award amount
   • 5R01MH125579-03Department: NIH department code

     Resolving complex alternative splicing of psychiatric disease genes using single-cell approaches
     $756,883

     award amount
   • 5R01MH121074-05Department: NIH department code

     Cell-type-specific NRXN1alpha alternative splicing changes in psychiatric disease
     $741,061

     award amount

5. Sharp, Andrew James

   Leads 1 award · $2,206,266

   • 1RF1AG075051-01A1Department: NIH department code

     A comprehensive study of tandem repeat variation as a cause of Alzheimer's disease
     $2,206,266

     award amount

6. Geschwind, Daniel H

   Leads 3 awards · $1,888,526

   • 5U54NS123746-03Department: NIH department code

     Uncovering the genetic mechanisms of the Chromosome 17q21.31 Tau haplotype on neurodegeneration risk in FTD and PSP
     $1,827,156

     award amount
   • 3U54NS123746-03S1Department: NIH department code

     Uncovering the genetic mechanisms of the Chromosome 17q21.31 Tau haplotype on neurodegeneration risk in FTD and PSP
     $37,683

     award amount
   • 3U54NS123746-02S1Department: NIH department code

     Uncovering the Genetic Mechanisms of the Chromosome 17q21.31 Tau Haplotype on Neurodegeneration Risk in FTD and PSP
     $23,687

     award amount

7. Faith, Jeremiah James

   Leads 3 awards · $1,535,845

   • 2R01DK112978-05Department: NIH department code

     The Influence Of Gut Microbiota Stability In Inflammatory Bowel Disease
     $604,914

     award amount
   • 5R01DK124133-04Department: NIH department code

     Uncovering the rules of gut microbiome strain transmission
     $592,931

     award amount
   • 5R01DK130337-02Department: NIH department code

     Comparison of defined live biotherapeutic product and fecal microbiota transplantation for treatment of recurrent Clostridioides difficile infection
     $338,000

     award amount

8. Jabs, Ethylin Wang

   Leads 2 awards · $1,525,122

   • 5R01DE029322-04Department: NIH department code

     Transcriptome and Network Analysis of Cleft Palate
     $793,404

     award amount
   • 5R01DE029832-03Department: NIH department code

     Genetic, Tissue, and Anatomical Interactions in Mandibulofacial Dysmorphogenesis
     $731,718

     award amount

9. Fang, Gang

   Leads 2 awards · $1,361,179

   • 5R35GM139655-03Department: NIH department code

     High Resolution Characterization of Bacterial Epigenomes and Microbiome
     $825,990

     award amount
   • 5R01HG011095-03Department: NIH department code

     Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome
     $535,189

     award amount

10. Balwani, Manisha

    Leads 1 award · $1,345,652

    • 5U54DK083909-15Department: NIH department code

      Porphyrias Consortium
      $1,345,652

      award amount

11. Do, Ron

    Leads 3 awards · $1,325,773

    • 5R01HL155915-03Department: NIH department code

      Elucidating hereditary transthyretin-mediated heart failure risk using machine learning, polygenic risk and recall by genotype approaches in African ancestry individuals
      $745,525

      award amount
    • 2R35GM124836-06Department: NIH department code

      Computational approaches to advance genomic, biological and clinical understandings of human disease
      $453,075

      award amount
    • 3R01HL155915-03S1Department: NIH department code

      Assessing effects of adverse Social Determinants of Health (SDOH) in TTR V122l carriers via Structured data and Natural Language Processing (NLP) extraction, a comparison
      $127,173

      award amount

12. O'Reilly, Paul Francis

    Leads 2 awards · $1,279,212

    • 1R01HG012773-01A1Department: NIH department code

      BridgePRS: bridging the gap in polygenic risk scores between ancestries.
      $642,872

      award amount
    • 5R01MH122866-04Department: NIH department code

      Next-generation, pathway-specific, polygenic risk scores
      $636,340

      award amount

13. Dong, Yizhou

    Leads 2 awards · $1,242,814

    • 1R01AI174902-01Department: NIH department code

      Integration of adjuvant derived nanoparticles and engineered mRNA for HIV vaccine discovery
      $778,064

      award amount
    • 5R35GM144117-03Department: NIH department code

      Construction of in vivo mRNA delivery systems
      $464,750

      award amount

14. Crane, Heidi M.

    Leads 2 awards · $1,224,263

    • 5R01HG010649-05Department: NIH department code

      Pharmacogenomics and Systems Pharmacology Approaches to Toxicity, Tolerability, and Comorbidities Associated with Modern Antiretroviral Therapies
      $823,490

      award amount
    • 3R01HG010649-05S1Department: NIH department code

      Genetic Predisposition and Pharmacogenomics of HIV-Associated Cognitive Impairment
      $400,773

      award amount

15. Goate, Alison M

    Leads 1 award · $1,199,181

    • 5R01AG072489-02Department: NIH department code

      Neuroprotective signaling and transcriptional pathways in microglia associated with Alzheimer's disease
      $1,199,181

      award amount

16. Devita, Robert J

    Leads 2 awards · $1,125,573

    • 1R01HD112518-01Department: NIH department code

      Allosteric regulation of lysine degradation as a novel pathophysiological mechanism in glutaric aciduria type 1
      $725,595

      award amount
    • 5R01DK130094-02Department: NIH department code

      Preclinical Validation of Novel Gut-Restricted LRRK2 Inhibitors as Therapeutic Leads for IBD
      $399,978

      award amount

17. Pandey, Gaurav

    Leads 2 awards · $1,112,218

    • 5R01HG011407-03Department: NIH department code

      Integrating genomic and clinical data to predict disease phenotypes using heterogeneous ensembles
      $605,218

      award amount
    • 5U01CA271318-02Department: NIH department code

      Multi-modal data integration to identify kinase substrates
      $507,000

      award amount

18. Klein, Robert J.

    Leads 2 awards · $911,365

    • 5R01CA244948-03Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $688,765

      award amount
    • 3R01CA244948-03S1Department: NIH department code

      Genetic Predictors of Prostate Cancer Survival
      $222,600

      award amount

19. Turro, Ernest

    Leads 2 awards · $837,905

    • 1R01HL161365-01A1Department: NIH department code

      Integrative analysis of whole genomes and transcriptomes from multiple cell types in rare disease patients
      $668,905

      award amount
    • 1R03HD111492-01Department: NIH department code

      Bayesian genetic association analysis of all rare diseases in the Kids First cohort
      $169,000

      award amount

20. Ma'ayan, Avi

    Leads 1 award · $824,077

    • 5U24CA271114-02Department: NIH department code

      Proteogenomic translator for cancer biomarker discovery towards precision medicine
      $824,077

      award amount

21. Holmes, Greg Peter

    Leads 1 award · $794,170

    • 5R01DE030596-03Department: NIH department code

      Coronal Suture Development in Health and Disease
      $794,170

      award amount

22. Morava-Kozicz, Eva

    Leads 1 award · $785,788

    • 7U54NS115198-06Department: NIH department code

      Frontiers in Congenital Disorders of Glycosylation
      $785,788

      award amount

23. Marcora, Edoardo

    Leads 1 award · $745,765

    • 1R56AG081417-01Department: NIH department code

      Investigating the effects of APOE and APOE-related AD risk genes on human microglia activity and lipid metabolism in aging and disease
      $745,765

      award amount

24. Brown, Brian D

    Leads 1 award · $704,657

    • 5R01AT011326-04Department: NIH department code

      Development of a platform for spatial functional genomics
      $704,657

      award amount

25. Yasuda, Makiko

    Leads 1 award · $655,405

    • 1R01DK134783-01Department: NIH department code

      Mechanisms of Intercellular Heme Homeostasis in Liver
      $655,405

      award amount

26. Forst, Christian

    Leads 1 award · $589,351

    • 5R01AI170112-02Department: NIH department code

      Deciphering the Heterogeneous Response to Influenza by a Multi-Scale Systems Approach
      $589,351

      award amount

27. Xu, Pin-Xian

    Leads 1 award · $580,953

    • 5R01DC014718-08Department: NIH department code

      Transcriptional networks establishing the precise gene expression states that define neurosensory cell identity in the inner ear
      $580,953

      award amount

28. Schuchman, Edward H.

    Leads 1 award · $522,796

    • 5R01HD109312-02Department: NIH department code

      Endocannabinoid-Based Treatment for the Neurologic Niemann-Pick Diseases
      $522,796

      award amount

29. Charney, Alexander W

    Leads 1 award · $429,337

    • 5R01MH121923-05Department: NIH department code

      3/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders
      $429,337

      award amount

30. Huang, Kuan-Lin

    Leads 1 award · $423,069

    • 5R35GM138113-04Department: NIH department code

      Integrative Approaches for Identifying Causal Gene-Cell Type Pairs of Complex Disease
      $423,069

      award amount

31. Song, Won-Min

    Leads 1 award · $422,500

    • 5R35GM142918-03Department: NIH department code

      Integrative network modeling of bulk and single-cell sequencing data to characterize multi-scale cell architecture
      $422,500

      award amount

32. Tocheva, Anna S

    Leads 1 award · $422,500

    • 1R35GM150989-01Department: NIH department code

      Molecular mechanisms underlying T cell resistance to PD-1 signaling
      $422,500

      award amount

33. Lozano, Reymundo

    Leads 1 award · $271,455

    • 5K01NS126736-02Department: NIH department code

      FXTAS Key Molecular Pathways Converge with Other Neurodegenerative Disorders
      $271,455

      award amount

34. Jiang, Wenyan

    Leads 1 award · $249,000

    • 4R00AI153530-03Department: NIH department code

      New CRISPR tools for systematic interrogation of genetic and transcriptional determinants of antibiotic sensitivity in bacteria
      $249,000

      award amount

35. Pejaver, Vikas Rao

    Leads 1 award · $236,548

    • 5R00LM012992-04Department: NIH department code

      Integrative data science approaches for rare disease discovery in health records
      $236,548

      award amount

36. Liu, Bian

    Leads 1 award · $211,250

    • 5R21DK131555-02Department: NIH department code

      Development of a Simple Youth Diabetes Screening Tool Using Machine Learning
      $211,250

      award amount

37. Ioannou, Yiannis A

    Leads 1 award · $169,219

    • 5R21HD108675-02Department: NIH department code

      Targeting the lysosome-mitochondria axis in neurodegenerative lysosomal storage diseases - Lessons from telomerase immortalization
      $169,219

      award amount

38. Tsankov, Alexander Minchev

    Leads 1 award · $126,750

    • 5R21HL161760-02Department: NIH department code

      Comparative, single-cell analysis of COVID-19 and other respiratory diseases
      $126,750

      award amount

39. Garretti, Francesca

    Leads 1 award · $69,080

    • 1F32AG082483-01Department: NIH department code

      Investigating the role of an EIF2B3 variant as an Alzheimer's disease risk modifier
      $69,080

      award amount

40. Charytonowicz, Daniel

    Leads 1 award · $52,694

    • 5F30CA265288-03Department: NIH department code

      Defining and targeting the lung cancer progenitor cell niche using a high-resolution, multi-omics approach
      $52,694

      award amount

41. Levantovsky, Rachel

    Leads 1 award · $52,694

    • 5F30DK127736-03Department: NIH department code

      Defining mechanisms of perianal fistula inception in African and European ancestry Crohn's disease patients
      $52,694

      award amount

42. Seah, Carina

    Leads 1 award · $51,854

    • 1F30MH132324-01A1Department: NIH department code

      Modeling gene x environment interactions in post-traumatic stress disorder.
      $51,854

      award amount

43. Munch, Alexandra

    Leads 1 award · $46,094

    • 1F31AG084337-01Department: NIH department code

      Uncovering the Role of the MS4A Gene Family in Alzheimer's Disease
      $46,094

      award amount

44. Retallick-Townsley, Kayla

    Leads 1 award · $46,094

    • 5F31MH130122-02Department: NIH department code

      Massively Parallel Characterization of Cell-type and Context Specific Regulatory Risk Elements Across Psychiatric Disorders in a Stem Cell Model of Neurodevelopment
      $46,094

      award amount