Genetics at Massachusetts General Hospital

Leads a grant in this department

57 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Hyon K Choi

   Leads 1 award · $1,937,050

   • 5U01AR080985-02Department: topic-inferred

     Treat-to-Target Serum Urate versus Treat-to-Avoid Symptoms in Gout: A Randomized Controlled Trial (TRUST)

     Principal investigators: Hyon K Choi (contact PI), Daniel Hal Solomon, Michael J Barry

     $1,937,050

     award amount

2. Emi Takahashi (oki)

   Leads 1 award · $1,896,457

   • 1R01HD111454-01A1Department: topic-inferred

     Brain Development in Down Syndrome during Fetal and Early Postnatal Ages
     $1,896,457

     award amount

3. Patrick Thomas Ellinor

   Leads 2 awards · $1,411,904

   • 5R01HL092577-16Department: topic-inferred

     IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL

     Principal investigators: Patrick Thomas Ellinor (contact PI), Emelia J. Benjamin, Kathryn L Lunetta

     $706,324

     award amount
   • 5R01HL157635-03Department: topic-inferred

     Using Electrocardiogram Genetics to Inform Arrhythmia Risk

     Principal investigators: Patrick Thomas Ellinor (contact PI), Tooraj Mirshahi

     $705,580

     award amount

4. Michael E Talkowski

   Leads 2 awards · $1,369,229

   • 5R01HD081256-09Department: topic-inferred

     Clinical Diagnostic Sequencing of Structural Variation
     $705,513

     award amount
   • 2R01NS102423-06Department: topic-inferred

     Assembling the Genetic Architecture of X-linked Dystonia Parkinsonism

     Principal investigators: Michael E Talkowski (contact PI), Clotilde Lagier-Tourenne, David Cristopher Bragg

     $663,716

     award amount

5. Vanessa C Wheeler

   Leads 2 awards · $1,308,913

   • 5R01NS049206-18Department: topic-inferred

     Huntington's Disease Repeat Instability and Pathogenesis
     $668,849

     award amount
   • 5R01NS127866-02Department: topic-inferred

     Dissecting the role of DNA Ligase 1 in Huntington's disease

     Principal investigators: Vanessa C Wheeler (contact PI), Ihn Sik Seong

     $640,064

     award amount

6. Tatsuo Kawai

   Leads 1 award · $1,074,783

   • 5U01AI174968-02Department: topic-inferred

     Targeting innate immunity for induction of robust renal allograft tolerance

     Principal investigators: Tatsuo Kawai (contact PI), M. Amin Arnaout

     $1,074,783

     award amount

7. Gary B Ruvkun

   Leads 2 awards · $1,068,678

   • 5R01GM044619-32Department: topic-inferred

     Control of C. elegans Lineage by Heterochronic Genes
     $636,718

     award amount
   • 5R01AG016636-25Department: topic-inferred

     Genetic and Molecular Basis of Longevity
     $431,960

     award amount

8. Carlos Arturo Camargo

   Leads 1 award · $832,707

   • 5UG3OD023253-09Department: topic-inferred

     Host genetics, early-life microbiome, and childhood asthma: MARC-43 Boston
     $832,707

     award amount

9. Miriam Sargon Udler

   Leads 1 award · $784,636

   • 1U01DK140757-01Department: topic-inferred

     GEneration and assessment of Multi-omic informed Subtypes of Type 2 Diabetes in Diverse Populations (GEMS-T2D)

     Principal investigators: Miriam Sargon Udler (contact PI), Josep Maria Mercader, Kristina Marie Utzschneider

     $784,636

     award amount

10. Albert S. Yeung

    Leads 1 award · $750,079

    • 1R34AT012922-01Department: topic-inferred

      Development and Pilot Testing of a Combined SMART and Tai Chi Intervention for Asian Americans with Depression and Somatic Symptoms
      $750,079

      award amount

11. Harrison Brand

    Leads 1 award · $739,644

    • 5R01DE031261-03Department: topic-inferred

      Integration of polygenic risk and facial morphometrics to decipher the genetic susceptibility of orofacial clefting
      $739,644

      award amount

12. Tian Ge

    Leads 1 award · $732,244

    • 5R01MH130899-02Department: topic-inferred

      Leveraging computational strategies to disentangle the genetic and neural underpinnings of ADHD and its associated cognitive systems
      $732,244

      award amount

13. Alisa Knodle Manning

    Leads 1 award · $709,961

    • 5UM1DK078616-16Department: topic-inferred

      TOPMed Omics of Type 2 Diabetes and Quantitative Traits
      $709,961

      award amount

14. Pradeep Natarajan

    Leads 1 award · $697,700

    • 2R01HL142711-06Department: topic-inferred

      Whole genome sequences in ethnically diverse individuals to comprehensively characterize the genetic mechanisms of dyslipidemias

      Principal investigators: Pradeep Natarajan (contact PI), Gina Marie Peloso

      $697,700

      award amount

15. Patricia L Musolino

    Leads 1 award · $696,219

    • 5R01NS125353-03Department: topic-inferred

      Modeling and Therapeutic Approaches for Genetic Vasculopathies

      Principal investigators: Patricia L Musolino (contact PI), Mark E Lindsay

      $696,219

      award amount

16. Heidi Irma Jacobs

    Leads 1 award · $684,216

    • 5R01AG082006-02Department: topic-inferred

      Locus coeruleus network architecture of Alzheimer's disease vulnerability

      Principal investigators: Heidi Irma Jacobs (contact PI), Jorge Sepulcre

      $684,216

      award amount

17. James F Gusella

    Leads 1 award · $669,847

    • 5R01NS091161-10Department: topic-inferred

      Disease-Modifying Genes in Huntington's Disease
      $669,847

      award amount

18. Jeannie T Lee

    Leads 2 awards · $667,783

    • 5R01GM058839-26Department: topic-inferred

      Regulation of X-chromosome inactivation and imprinting by non-coding elements
      $475,535

      award amount
    • 3R01GM058839-26S1Department: topic-inferred

      Regulation of X-chromosome inactivation and imprinting by non-coding elements
      $192,248

      award amount

19. Hailiang Huang

    Leads 1 award · $654,644

    • 5R01DK129364-03Department: topic-inferred

      Identification and characterization of inflammatory bowel disease causal variants
      $654,644

      award amount

20. Anastasia Yendiki

    Leads 1 award · $632,897

    • 9R01NS127353-05A1Department: topic-inferred

      Mapping human neurocircuitry across scales with diffusion MRI and optical imaging
      $632,897

      award amount

21. Cenk Ayata

    Leads 1 award · $622,548

    • 5U01NS130588-02Department: topic-inferred

      Stroke Preclicinal Assessment Network
      $622,548

      award amount

22. Toshihiro Shioda

    Leads 1 award · $620,940

    • 1R01ES035401-01A1Department: topic-inferred

      Environmental chemicals impair epigenetic suppression of the endogenous retrovirus HML-2 in human primordial germ cells, predisposing the next generation to malignancies through HML-2 reactivation
      $620,940

      award amount

23. Evan Andrew Bordt

    Leads 1 award · $584,610

    • 5R01HD110467-02Department: topic-inferred

      Perinatal Gonadal Hormones Impart Male-Biased Neuroimmune, Mitochondrial, and Behavioral Vulnerabilities.
      $584,610

      award amount

24. Kristopher T. Kahle

    Leads 1 award · $532,195

    • 5R01NS117609-05Department: topic-inferred

      Human Genetics and Molecular Mechanisms of Vein of Galen Aneurysmal Malformation

      Principal investigators: Kristopher T. Kahle (contact PI), Titus Jonathon Boggon

      $532,195

      award amount

25. Mario Luca Suva

    Leads 1 award · $530,162

    • 5R01CA258763-04Department: topic-inferred

      Deciphering heritability, plasticity and differentiation trajectories in gliomas via single-cell multi-omics
      $530,162

      award amount

26. Daniel C Chung

    Leads 1 award · $493,563

    • 5U01CA243695-05Department: topic-inferred

      Development and Implementation of ElectronicDecision Aids for Genetic Testing in Inherited Cancer Syndromes
      $493,563

      award amount

27. Ricardo Mouro Pinto

    Leads 1 award · $400,178

    • 5R01NS126420-03Department: topic-inferred

      Somatic Repeat Expansions as a Therapeutic Target for Trinucleotide Repeat Disorders
      $400,178

      award amount

28. Jordan W Smoller

    Leads 1 award · $388,448

    • 2T32HG010464-06Department: topic-inferred

      Mass General Brigham Training Program in Precision and Genomic Medicine

      Principal investigators: Jordan W Smoller (contact PI), Heidi L Rehm

      $388,448

      award amount

29. Ihn Sik Seong

    Leads 1 award · $382,956

    • 5R01NS114065-05Department: topic-inferred

      An Alternative Isoform of RRM2B as a Genetic Modifier in Huntington's Disease
      $382,956

      award amount

    Also a principal investigator on 5R01NS127866-02, led by Vanessa C Wheeler.

30. Lauren Lynn Orefice

    Leads 1 award · $378,239

    • 5R01NS126691-02Department: topic-inferred

      Development, Function, and Dysfunction of Gastrointestinal Tract-Innervating Dorsal Root Ganglia Neurons in Autism Spectrum Disorder
      $378,239

      award amount

31. Merit E Cudkowicz

    Leads 1 award · $296,964

    • 1OT2NS138339-01Department: topic-inferred

      Gene Therapy Consortium (GTC) for Gene-Based Clinical Trials Conducted within NeuroNEXT
      $296,964

      award amount

32. Scott R Plotkin

    Leads 1 award · $290,694

    • 1U24NS131158-01A1Department: topic-inferred

      Neurofibromatosis and Schwannomatosis Genes Variant Curation Expert Panel (VCEP)

      Principal investigators: Scott R Plotkin (contact PI), Elisabeth Castellanos

      $290,694

      award amount

33. Wei Zhou

    Leads 1 award · $249,000

    • 4R00HG012222-03Department: topic-inferred

      An integrative approach to disease gene discovery combining genetic variation, gene expression, and epigenetics.
      $249,000

      award amount

34. Zhi Yu

    Leads 1 award · $249,000

    • 4R00HG012956-02Department: topic-inferred

      Multi-omic dissection of clonal hematopoiesis-associated diseases
      $249,000

      award amount

35. Christiano Alves

    Leads 1 award · $244,458

    • 1K01NS134784-01Department: topic-inferred

      Development of in Vivo Base Editing as a Genetic Treatment for Spinal Muscular Atrophy
      $244,458

      award amount

36. Nina Beth Gold

    Leads 1 award · $227,362

    • 5K08HG012811-02Department: topic-inferred

      Genome-first approach to treatable genetic conditions in adults
      $227,362

      award amount

37. Leland Hull

    Leads 1 award · $219,734

    • 5K08HG012221-03Department: topic-inferred

      Elucidating the barriers and facilitators to widespread implementation of preconception genetic carrier screening
      $219,734

      award amount

38. Mark Christian Eldaief

    Leads 1 award · $208,750

    • 1R21AG088872-01Department: topic-inferred

      Characterizing autonomic impairments in Frontotemporal Dementia
      $208,750

      award amount

39. Xingbin Ai

    Leads 1 award · $208,750

    • 5R21AI173494-02Department: topic-inferred

      COVID-19 imprints airway basal cells to impair epithelium regeneration
      $208,750

      award amount

40. Mei X Wu

    Leads 1 award · $208,410

    • 1R21AI183486-01Department: topic-inferred

      A novel bacteria-specific pro-photosensitizer
      $208,410

      award amount

41. Melissa Anne Walker

    Leads 1 award · $200,880

    • 5K08NS117889-04Department: topic-inferred

      Dual Genome Omics: Adapting Genomics Techniques to Reveal Molecular Pathology in Mitochondrial Disease
      $200,880

      award amount

42. Jacob Eric Lazarus

    Leads 1 award · $199,702

    • 5K08AI155830-04Department: topic-inferred

      Intrinsic modifiers of beta-lactam resistance in nosocomial Enterobacterales
      $199,702

      award amount

43. Philip Michael Boone

    Leads 1 award · $197,638

    • 5K08NS117891-05Department: topic-inferred

      Defining the Disorders of Genome Organization
      $197,638

      award amount

44. Aaron Jonathan Deutsch

    Leads 1 award · $191,750

    • 1K23DK140643-01Department: topic-inferred

      Multi-Ancestry Genetic Analysis of Type 1 Diabetes and Related Conditions
      $191,750

      award amount

45. Jack Minyang Fu

    Leads 1 award · $183,663

    • 1K01MH137407-01Department: topic-inferred

      Integration of common, rare, and structural variation to define the genetic architecture of neuropsychiatric disorders
      $183,663

      award amount

46. Cory Perugino

    Leads 1 award · $174,960

    • 5K08AR079615-04Department: topic-inferred

      Defining the antigenic determinants of the adaptive immune response in IgG4-related disease
      $174,960

      award amount

47. Aniruddh Patel

    Leads 1 award · $170,323

    • 1K08HL168238-01A1Department: topic-inferred

      Advancing the clinical actionability of polygenic scores for coronary artery disease
      $170,323

      award amount

48. Donghai Wen

    Leads 1 award · $169,560

    • 5K08DK132411-03Department: topic-inferred

      Biological function of testican-2 in podocyte health
      $169,560

      award amount

49. Tony V Pham

    Leads 1 award · $169,556

    • 5K23AT012363-02Department: topic-inferred

      Mindfulness-Based Cognitive Therapy for the chronic pain-depression co-morbidity among older Blacks in the community; The Quiet Focus study
      $169,556

      award amount

50. Akl C Fahed

    Leads 1 award · $169,264

    • 5K08HL161448-03Department: topic-inferred

      Integrating genomic and nongenomic risk for coronary artery disease
      $169,264

      award amount

51. Sara Elizabeth Dolan Looby

    Leads 1 award · $163,971

    • 1R25LM014348-01A1Department: topic-inferred

      EMPOWHer: Embracing Midlife & Menopause Positively-Offerings by Women with HIV

      Principal investigators: Sara Elizabeth Dolan Looby (contact PI), Sara Hurtado Bares

      $163,971

      award amount

52. Kenneth E Westerman

    Leads 1 award · $146,880

    • 5K01DK133637-03Department: topic-inferred

      Improved detection of gene-diet interactions via longitudinal data, metabolomic proxies, and polygenic scores
      $146,880

      award amount

53. Jonathan R Polimeni

    Leads 1 award · $136,356

    • 3R01EB019437-08S1Department: topic-inferred

      fMRI Technologies for Imaging at the Limit of Biological Spatiotemporal Resolution

      Principal investigators: Jonathan R Polimeni (contact PI), Kawin Setsompop

      $136,356

      award amount

54. Xuefang Zhao

    Leads 1 award · $135,886

    • 5K99HD107222-02Department: topic-inferred

      Characterizing the genetic etiology of delayed puberty with integrative genomic techniques
      $135,886

      award amount

55. Kai Yuan

    Leads 1 award · $129,288

    • 1K99MH135172-01A1Department: topic-inferred

      Whole chromosome fine-mapping integrating diverse ancestries for psychiatric disorders
      $129,288

      award amount

56. Tiffany Bellomo

    Leads 1 award · $92,756

    • 1F32HL174327-01Department: topic-inferred

      Genetics of carotid artery disease progression among patients who have failed non-operative management
      $92,756

      award amount

57. Michael H Duyzend

    Leads 1 award · $87,892

    • 5F32HD112084-02Department: topic-inferred

      Comprehensive and non-invasive prenatal screening of coding variation
      $87,892

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Daniel Hal Solomon

  Co-investigator on 5U01AR080985-02, led by Hyon K Choi

  From the FY2024 awards this person leads

  • Brigham and Women's Hospital · Internal Medicine (topic-inferred, 2 awards)

• Michael J Barry

  Co-investigator on 5U01AR080985-02, led by Hyon K Choi

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• M. Amin Arnaout

  Co-investigator on 5U01AI174968-02, led by Tatsuo Kawai

  From the FY2024 awards this person leads

  • Massachusetts General Hospital · Urology (topic-inferred, 1 award)

• Josep Maria Mercader

  Co-investigator on 1U01DK140757-01, led by Miriam Sargon Udler

  From the FY2024 awards this person leads

  • Broad Institute, Inc. (no department on record, 1 award)

• Kristina Marie Utzschneider

  Co-investigator on 1U01DK140757-01, led by Miriam Sargon Udler

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Emelia J. Benjamin

  Co-investigator on 5R01HL092577-16, led by Patrick Thomas Ellinor

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Kathryn L Lunetta

  Co-investigator on 5R01HL092577-16, led by Patrick Thomas Ellinor

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Tooraj Mirshahi

  Co-investigator on 5R01HL157635-03, led by Patrick Thomas Ellinor

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Gina Marie Peloso

  Co-investigator on 2R01HL142711-06, led by Pradeep Natarajan

  From the FY2024 awards this person leads

  • Boston University · Biostatistics & Math Sciences (NIH department code, 1 award)

• Mark E Lindsay

  Co-investigator on 5R01NS125353-03, led by Patricia L Musolino

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Jorge Sepulcre

  Co-investigator on 5R01AG082006-02, led by Heidi Irma Jacobs

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Clotilde Lagier-Tourenne

  Co-investigator on 2R01NS102423-06, led by Michael E Talkowski

  From the FY2024 awards this person leads

  • Massachusetts General Hospital · Neurosciences (topic-inferred, 2 awards)

• David Cristopher Bragg

  Co-investigator on 2R01NS102423-06, led by Michael E Talkowski

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Titus Jonathon Boggon

  Co-investigator on 5R01NS117609-05, led by Kristopher T. Kahle

  From the FY2024 awards this person leads

  • Yale University · Pharmacology (NIH department code, 3 awards)

• Heidi L Rehm

  Co-investigator on 2T32HG010464-06, led by Jordan W Smoller

  From the FY2024 awards this person leads

  • Broad Institute, Inc. (no department on record, 3 awards)

• Elisabeth Castellanos

  Co-investigator on 1U24NS131158-01A1, led by Scott R Plotkin

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Sara Hurtado Bares

  Co-investigator on 1R25LM014348-01A1, led by Sara Elizabeth Dolan Looby

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Kawin Setsompop

  Co-investigator on 3R01EB019437-08S1, led by Jonathan R Polimeni

  From the FY2024 awards this person leads

  • Stanford University · Radiology (NIH department code, 1 award)