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FY2025 NIH awards · Principal investigators

Engineering at Massachusetts Institute of Technology

Cambridge, MA

Funding
$32.2M
$32,191,290
Awards
53
FY2025 NIH awards in Engineering
Principal investigators
59
36 lead a grant here, 23 co-investigators
Department rank
Not ranked
Outside the 27 ranked departments
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Engineering row of the Massachusetts Institute of Technology page.

Leads a grant in this department

36 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Manolis Kellis

    Leads 5 awards · $4,089,484

    • 5R01AG074003-05Department: NIH department code
      Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimer’s Disease

      Principal investigators: Manolis Kellis (contact PI), Li-Huei Tsai

      $1,068,252
      award amount
    • 4R01NS129032-02Department: NIH department code
      Single-cell multi-region transcriptional and epigenomic dissection of VCID.

      Principal investigators: Manolis Kellis (contact PI), Myriam Heiman

      $1,034,087
      award amount
    • 5R01AG081017-03Department: NIH department code
      Single-cell multi-region dissection of AD-pathogen interactions for HSV-1 and CMV

      Principal investigators: Manolis Kellis (contact PI), Rudolph Emile Tanzi

      $727,847
      award amount
    • 5R01AG067151-05Department: NIH department code
      Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD

      Principal investigators: Manolis Kellis (contact PI), Veronique Belzil

      $700,630
      award amount
    • 1R01DA063327-01Department: NIH department code
      Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV

      Principal investigators: Manolis Kellis (contact PI), Myriam Heiman

      $558,668
      award amount

  2. Ernest Fraenkel

    Leads 2 awards · $2,953,444

    • 4RF1AG075901-02Department: NIH department code
      The effects of Alzheimer's disease risk genes on metabolism and signaling across cell types

      Principal investigators: Ernest Fraenkel (contact PI), Li-Huei Tsai

      $2,533,330
      award amount
    • 5U01CA253547-05Department: NIH department code
      Identifying therapeutic pathways targeting medulloblastoma-immune cell interactions

      Principal investigators: Ernest Fraenkel (contact PI), Jill P. Mesirov

      $420,114
      award amount

  3. Peter T. So

    Leads 2 awards · $2,845,087

    • 1R01GM160726-01Department: NIH department code
      High Throughput End-to-End Design of Quantitative Phase Microscopy based on Customizable Nano-Optics
      $1,963,850
      award amount
    • 5UH3CA275687-04Department: NIH department code
      Single-cell label-free identification of senescence by Raman microscopy and spatial genomics

      Principal investigators: Peter T. So (contact PI), Jeon Woong Kang, Jian Shu

      $881,237
      award amount

  4. Alan Jasanoff

    Leads 5 awards · $2,343,502

    • 4UH3MH126868-04Department: NIH department code
      Hemogenetic imaging technology for circuit-specific analysis of primate brain function
      $626,140
      award amount
    • 1R01DA062195-01Department: NIH department code
      Analyzing brain-wide bases of neuroplastic change using new imaging tools
      $613,107
      award amount
    • 5U01EB031641-05Department: NIH department code
      Toward functional molecular neuroimaging using vasoactive probes in human subjects
      $527,497
      award amount
    • 5R01NS121073-04Department: NIH department code
      Analysis of Integrated Brain Functions Using Hemogenetic Imaging
      $489,403
      award amount
    • 5T32EB019940-10Department: NIH department code
      Neurobiological Engineering Training Program
      $87,355
      award amount

  5. Kwanghun Chung

    Leads 1 award · $1,861,894

    • 5U01AG077227-04Department: NIH department code
      Mapping the vulnerable locus coeruleus pathways in aging and AD

      Principal investigators: Kwanghun Chung (contact PI), Li-Huei Tsai

      $1,861,894
      award amount

  6. Daniel G Anderson

    Leads 3 awards · $1,763,590

    • 5R33AI161805-05Department: NIH department code
      Combinatorial and computational design of bnAb mRNA vaccines for HIV
      $771,167
      award amount
    • 5R01EB031992-04Department: NIH department code
      SMART BIOELECTRONIC IMPLANTS FOR CONTROLLED DELIVERY OF THERAPEUTIC PROTEINS IN VIVO AND ITS APPLICATION IN LONG-TERM TREATMENT OF HEMOPHILIA A
      $604,673
      award amount
    • 5R01HL162564-04Department: NIH department code
      Nonviral delivery techniques for in vivo prime editing
      $387,750
      award amount

  7. Li-Wei H Lehman

    Leads 2 awards · $1,632,434

    • 1R01HL181348-01Department: NIH department code
      Emulated Target Trials and Phenotyping in Patients with Acute Respiratory Distress Syndrome

      Principal investigators: Li-Wei H Lehman (contact PI), Elias Baedorf Kassis, Zachary Shahn

      $1,479,335
      award amount
    • 1R21HL177773-01Department: NIH department code
      Emulated Target Trials of Steroids in Patients with Acute Respiratory Distress Syndrome

      Principal investigators: Li-Wei H Lehman (contact PI), Elias Baedorf Kassis, Zachary Shahn

      $153,099
      award amount

  8. Ron Weiss

    Leads 2 awards · $1,278,818

    • 5U01CA265706-05Department: NIH department code
      Immunotherapy via engineered therapeutic programs in tumors using RNA

      Principal investigators: Ron Weiss (contact PI), Darrell J Irvine, Yizhou Dong

      $639,680
      award amount
    • 5R01HD105947-05Department: NIH department code
      Genetically Programmed Pancreatic Organoids with Self-Adaptive Multi-Lineage Population Control
      $639,138
      award amount

  9. Anders Sejr Hansen

    Leads 2 awards · $1,011,852

    • 5R01CA300848-02Department: NIH department code
      Resolving transcription factor target search mechanisms
      $588,426
      award amount
    • 5R01EB035127-02Department: NIH department code
      An integrated toolkit for real-time analysis of coupled nascent transcription
      $423,426
      award amount

  10. Polina O Anikeeva

    Leads 1 award · $977,130

    • 5DP1AT011991-05Department: NIH department code
      Fusion of nanomagnetic and viral tools to interrogate brain-body circuits
      $977,130
      award amount

  11. Linda G Griffith

    Leads 2 awards · $879,026

    • 5R01HD114214-03Department: NIH department code
      Integrating tissue engineering and microfluidics to model the spatial niches of the human endometrium in vitro with guidance from in vivo multiomics data

      Principal investigators: Linda G Griffith (contact PI), Douglas A Lauffenburger, Roser Vento-Tormo

      $555,359
      award amount
    • 5R01HD110335-04Department: NIH department code
      Parsing the Interplay Between Biophysical and Biochemical Microenvironment Cues On Endometriosis Lesion Phenotypes Using Microphysiological Systems
      $323,667
      award amount

  12. James G Fujimoto

    Leads 2 awards · $843,291

    • 5R01CA249151-05Department: NIH department code
      Increasing nerve-sparing radical prostatectomy rates using intraoperative nonlinear microscopy
      $437,140
      award amount
    • 5R01EY034080-03Department: NIH department code
      Novel ultrahigh speed swept source OCT angiography methods in diabetic retinopathy

      Principal investigators: James G Fujimoto (contact PI), Nadia Waheed

      $406,151
      award amount

  13. Thomas Heldt

    Leads 1 award · $783,198

    • 1U24EB037545-01Department: NIH department code
      PhysioNet: A FAIR and sustainable data repository

      Principal investigators: Thomas Heldt (contact PI), Tom Pollard

      $783,198
      award amount

  14. Elazer R Edelman

    Leads 1 award · $684,671

    • 5R01HL161069-04Department: NIH department code
      Personalized lesion modification optimizes atherosclerosis intervention
      $684,671
      award amount

  15. Xuanhe Zhao

    Leads 1 award · $635,663

  16. Michal Caspi Tal

    Leads 1 award · $606,738

    • 5R01AI178713-03Department: NIH department code
      Unlocking serology’s secrets: harnessing novel immune biomarkers to predict Lyme disease progression and recovery
      $606,738
      award amount

  17. Roozbeh Jafari

    Leads 1 award · $568,240

    • 5R01EB034821-03Department: NIH department code
      A Smart Ring for Cuffless Blood Pressure to Reduce Health Disparities in People of Color

      Principal investigators: Roozbeh Jafari (contact PI), Roderic I. Pettigrew

      $568,240
      award amount

  18. Michael J Cima

    Leads 1 award · $540,178

    • 5R01EB031813-04Department: NIH department code
      NMR-Based Rapid Fluid Assessment: Device Design and Signal Processing

      Principal investigators: Michael J Cima (contact PI), Sagar Nigwekar

      $540,178
      award amount

  19. Roger D Kamm

    Leads 1 award · $516,335

    • 5R01NS121078-05Department: NIH department code
      Human 3D Neuro-Vascular Interaction and Meningeal Lymphatic Models with Application to Alzheimer’s Disease

      Principal investigators: Roger D Kamm (contact PI), Mehdi Jorfi, Se Hoon Choi

      $516,335
      award amount

  20. Tami D Lieberman

    Leads 1 award · $465,291

    • 1R01AR084097-01A1Department: NIH department code
      Determinants of colonization for commensal skin bacteria
      $465,291
      award amount

  21. Rohit N Karnik

    Leads 1 award · $424,265

    • 1R21AI187800-01A1Department: NIH department code
      Rapid culture-free analysis of bloodstream pathogens for transforming sepsis care

      Principal investigators: Rohit N Karnik (contact PI), Loza Tadesse

      $424,265
      award amount

  22. Mark Bathe

    Leads 1 award · $416,750

    • 2R01MH112694-06Department: NIH department code
      Simultaneous profiling of neuronal synapse activities, proteins, and messenger RNAs at the single-cell level
      $416,750
      award amount

  23. Ming Guo

    Leads 1 award · $415,791

    • 5R01GM140108-05Department: NIH department code
      Mechanobiology of Vimentin Intermediate Filaments in 3D Collective Cell Migration

      Principal investigators: Ming Guo (contact PI), Ian Y Wong

      $415,791
      award amount

  24. Heather J. Kulik

    Leads 1 award · $397,500

    • 5R35GM152027-02Department: NIH department code
      Revealing Nature's Blueprints for Single-Site Catalysis of C-H Activation with First-principles Modeling and Machine Learning
      $397,500
      award amount

  25. Ellen T. Roche

    Leads 1 award · $397,034

    • 1R61HL177503-01A1Department: NIH department code
      A transcatheter manufacturing toolkit for minimally-invasive and patient-specific device-based stroke prevention
      $397,034
      award amount

  26. Darcy McRose

    Leads 1 award · $393,718

    • 1R35GM157324-01Department: NIH department code
      Biogeography of Microbial and Plant-Derived Redox-Active Small Molecules and Combinatorial Effects on Microbial Growth
      $393,718
      award amount

  27. John M Essigmann

    Leads 1 award · $387,750

    • 5R01CA080024-28Department: NIH department code
      Intra and Extra-Chromosomal Probes for Mutagenesis by Carcinogens
      $387,750
      award amount

  28. Kate Elizabeth Galloway

    Leads 1 award · $387,750

    • 5R35GM143033-05Department: NIH department code
      Multiscale tools and approaches for understanding and engineering cell-fate transitions
      $387,750
      award amount

  29. Bevin P. Engelward

    Leads 1 award · $374,106

    • 5R01CA290188-02Department: NIH department code
      Impact of DNA Repair Pathway Interactions on the Molecular and Physiological Consequences of Methylation Damage
      $374,106
      award amount

  30. Bonnie Berger

    Leads 1 award · $359,830

    • 5R35GM141861-05Department: NIH department code
      Manifold representations and active learning for 21 st century biology
      $359,830
      award amount

  31. Paula T Hammond

    Leads 1 award · $353,924

    • 2R01CA235375-06Department: NIH department code
      Delivery of cytokines for cancer immunotherapy using nanolayer-controlled trafficking of liposomal nanoparticles

      Principal investigators: Paula T Hammond (contact PI), Darrell J Irvine

      $353,924
      award amount

  32. Bruce R Rosen

    Leads 1 award · $305,732

    • 2T32EB001680-21Department: NIH department code
      Neuroimaging Training Program
      $305,732
      award amount

  33. Yonatan Chemla

    Leads 1 award · $133,332

    • 1K99HG014240-01Department: NIH department code
      Functional Mapping of Translation Initiation Kinetics to Quantify the Protein-Coding Capacity of the Human Genome
      $133,332
      award amount

  34. Sumin Kim

    Leads 1 award · $75,520

    • 1F32GM156065-01A1Department: NIH department code
      Elucidating the Dynamics and Function of Long-Range Polycomb Interactions
      $75,520
      award amount

  35. Clarice Kit Yee Hong

    Leads 1 award · $75,052

    • 1F32GM154393-01A1Department: NIH department code
      Dynamics and mechanisms of long-range enhancer activity
      $75,052
      award amount

  36. Kimberly K Lamberti

    Leads 1 award · $13,370

    • 5F31HL170537-02Department: NIH department code
      Optimization of Right and Left Ventricular Coupling During Mechanical Circulatory Support
      $13,370
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.