Biochemistry at Tufts University

Leads a grant in this department

28 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Hu, Linden T

   Leads 1 award · $5,147,109

   • 1C06OD032006-01A1Department: NIH department code

     Laboratory for Combinatorial Drug Regimen Design for Resistant and Emerging Pathogens
     $5,147,109

     award amount

2. Aldridge, Bree Beardsley

   Leads 2 awards · $1,535,828

   • 5R01AI150684-03Department: NIH department code

     Lesion-centric optimization of multidrug therapies for tuberculosis
     $827,669

     award amount
   • 5R01AI143611-03Department: NIH department code

     Single-cell factors of tuberculosis drug tolerance during adaptation to environmental stressors
     $708,159

     award amount

3. Tan, Shumin

   Leads 3 awards · $1,059,182

   • 5R01AI143768-04Department: NIH department code

     Mycobacterium tuberculosis environmental signal integration: single cell in vivo understanding of its influence on infection heterogeneity and treatment efficacy
     $566,132

     award amount
   • 1R21AI171356-01Department: NIH department code

     Elucidating the link between Mycobacterium tuberculosis potassium homeostasis and its lipid metabolism and growth in vivo
     $247,500

     award amount
   • 1R21AI168597-01Department: NIH department code

     Unraveling the link between serine/threonine protein kinase and two-component system regulation of environment-mediated Mycobacterium tuberculosis growth arrest
     $245,550

     award amount

4. Shen, Aimee

   Leads 4 awards · $1,054,096

   • 5R01AI122232-08Department: NIH department code

     Spore Assembly in Clostridioides difficile
     $437,421

     award amount
   • 5R01GM140361-02Department: NIH department code

     Regulation of spore peptidoglycan modification
     $323,720

     award amount
   • 5R21AI153853-02Department: NIH department code

     Linking Gene Expression Profiles to Cell Fate in Clostridioides difficile Using Time-Lapse Microscopy
     $243,600

     award amount
   • 3R01GM140361-02S1Department: NIH department code

     Regulation of spore peptidoglycan modification
     $49,355

     award amount

5. Heldwein, Ekaterina

   Leads 2 awards · $958,548

   • 5R01AI164698-02Department: NIH department code

     Structure, antigenicity, and function of HCMV fusogen gB
     $758,575

     award amount
   • 5R21AI160821-02Department: NIH department code

     In-vitro analysis of HSV-1 membrane fusion mechanism
     $199,973

     award amount

6. Isberg, Ralph R.

   Leads 2 awards · $932,549

   • 5U01AI153415-03Department: NIH department code

     Molecular basis of metal acquisition by an intravacuolar pathogen
     $689,838

     award amount
   • 2T32AI007422-31Department: NIH department code

     Molecular Analysis of Microbial Pathogens
     $242,711

     award amount

7. Coffin, John M

   Leads 1 award · $922,751

   • 5R35CA200421-07Department: NIH department code

     Retrovirus Evolution and Cancer
     $922,751

     award amount

8. McVey, Mitch

   Leads 1 award · $914,409

   • 5K12GM133314-04Department: NIH department code

     Tufts IRACDA
     $914,409

     award amount

9. Schwob, James E.

   Leads 2 awards · $873,521

   • 5R01DC017869-03Department: NIH department code

     The Molecular Regulation of Horizontal Basal Cell Activation in the Olfactory Epithelium
     $626,021

     award amount
   • 1R21DC018681-01A1Department: NIH department code

     Driving the Progeny of Olfactory HBC Stem Cells toward Neuronal Differentiation
     $247,500

     award amount

10. Moore, Claire L

    Leads 2 awards · $790,791

    • 5R01AI152337-03Department: NIH department code

      Defining the Role of Alternative Polyadenylation in Macrophage Differentiation and Function
      $584,541

      award amount
    • 1R21AI164434-01A1Department: NIH department code

      The Role of alternative mRNA polyadenylation in SARS-CoV-2 replication & the host response
      $206,250

      award amount

11. Gaglia, Marta Maria

    Leads 2 awards · $771,846

    • 5R01AI137358-05Department: NIH department code

      Molecular Mechanism of Action of the Influenza PA-X Host Shutoff Protein
      $394,212

      award amount
    • 1R01CA268976-01Department: NIH department code

      Determining how Kaposi's sarcoma-associated herpesvirus hijacks caspase function to inhibit anti-viral responses
      $377,634

      award amount

12. Mecsas, Joan C

    Leads 1 award · $751,946

    • 1R01AI169786-01Department: NIH department code

      Dissecting Yersinia Yop Targets in Neutrophils
      $751,946

      award amount

13. Camilli, Andrew

    Leads 2 awards · $724,746

    • 5R37AI055058-18Department: NIH department code

      Impact of Bacteriophages on Virulence and Transmission of Vibrio cholerae
      $464,560

      award amount
    • 1T32GM139772-01A1Department: NIH department code

      Molecular Genetics of Basic Cell Function
      $260,186

      award amount

14. Raman, Malavika

    Leads 3 awards · $612,554

    • 5R01GM127557-05Department: NIH department code

      “Regulation of Protein Quality Control by the VCP AAA-ATPase”
      $346,500

      award amount
    • 1R21NS123631-01A1Department: NIH department code

      Investigating the impact of p97 mutation in Amyotrophic Lateral Sclerosis
      $247,500

      award amount
    • 3R01GM127557-05S1Department: NIH department code

      “Regulation of Protein Quality Control by the VCP AAA-ATPase”
      $18,554

      award amount

15. Feig, Larry

    Leads 2 awards · $524,306

    • 5R01HD100523-03Department: NIH department code

      Potential Role for Sperm miRNAs 34c and 449a in the Transgenerational Effects of Trauma in Men
      $276,806

      award amount
    • 1R21HD109721-01Department: NIH department code

      A novel system used by pre-implantation mammalian embryos to amplify environmentally-induced changes in sperm miRNA content after fertilization.
      $247,500

      award amount

16. Ng, Wai-Leung

    Leads 1 award · $479,710

    • 5R01AI121337-07Department: NIH department code

      Signaling Mechanisms in Vibrio Cholerae Parallel Quorum Sensing Pathways
      $479,710

      award amount

17. Lambert, Paul F.

    Leads 1 award · $459,214

    • 5R01CA228543-04Department: NIH department code

      Mouse Model of Human Papillomavirus Pathogenesis
      $459,214

      award amount

18. Gupta, Piyush

    Leads 1 award · $412,500

    • 5R01GM124491-05Department: NIH department code

      Defining the signaling pathways that direct adult tissue stem cells to exit multipotency
      $412,500

      award amount

19. Belitsky, Boris R

    Leads 3 awards · $371,250

    • 1R21AI166785-01A1Department: NIH department code

      The roles of glutathione metabolism in growth and virulence of Listeria monocytogenes
      $206,250

      award amount
    • 1R03AI171448-01Department: NIH department code

      Identification of a novel two-component system involved in peptidoglycan synthesis in Clostridioides difficile
      $82,500

      award amount
    • 5R03AI151205-02Department: NIH department code

      Identification of the full scope of the CodY regulon in Clostridioides difficile
      $82,500

      award amount

20. Kumamoto, Carol A.

    Leads 1 award · $243,600

    • 1R21AI168849-01Department: NIH department code

      Analyzing the Biogeography of Virulence and Transmission Gene Expression during Clostridioides difficile infection
      $243,600

      award amount

21. Leong, John M

    Leads 1 award · $213,824

    • 5R21AG071268-02Department: NIH department code

      Features of PMN Senescence that Lead to Susceptibility to Pneumococcal Infection
      $213,824

      award amount

22. Bullock, Peter Augustus

    Leads 1 award · $206,250

    • 1R21AI171309-01Department: NIH department code

      Testing the Polyomavirus-based Replication Dependent Enhancer Duplication Model
      $206,250

      award amount

23. Degterev, Alexei

    Leads 1 award · $206,250

    • 1R21NS124930-01A1Department: NIH department code

      Analyzing Oligodendrocytes-Derived Exosomes in Mouse Models of Multiple Sclerosis
      $206,250

      award amount

24. Munger, Karl

    Leads 1 award · $202,350

    • 5R21AI166786-02Department: NIH department code

      Mechanistic studies on the unique set of accessory proteins encoded by the gamma 6 human papillomaviruses
      $202,350

      award amount

25. Forgac, Michael D

    Leads 1 award · $185,414

    • 5R21CA245172-02Department: NIH department code

      Function of V-ATPases in Breast Cancer Metastasis
      $185,414

      award amount

26. Draganova, Elizabeth Bennett

    Leads 1 award · $44,132

    • 5K99AI151891-02Department: NIH department code

      Mechanisms of Conformational Dynamics and Inhibition of the HSV-1 Nuclear Egress Complex
      $44,132

      award amount

27. Chalom, Mayer Marc

    Leads 1 award · $42,348

    • 5F30DK128884-02Department: NIH department code

      Interleukin-13 in Central Regulation of Metabolism
      $42,348

      award amount

28. Forster, Emily Rachel

    Leads 1 award · $21,541

    • 5F31AI154814-03Department: NIH department code

      Mechanisms of Clostridioides difficile germinant and co-germinant sensing
      $21,541

      award amount