Pharmacology at University of California, San Diego

Leads a grant in this department

46 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Karin, Michael

   Leads 5 awards · $3,227,303

   • 1U01CA274295-01Department: NIH department code

     Regulation of PDAC metabolism and immunity by collagen and its cleavage products
     $971,140

     award amount
   • 1R01DK133448-01Department: NIH department code

     The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism
     $705,251

     award amount
   • 5R37AI043477-25Department: NIH department code

     NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of Inflammation
     $590,745

     award amount
   • 5R01CA234128-04Department: NIH department code

     Highly penetrant and immunogenic mouse models of non-viral HCC that are suitable for evaluation of immune checkpoint inhibitors
     $542,443

     award amount
   • 5R01DK120714-04Department: NIH department code

     Control of Lipogenesis and Hepatic Steatosis by Caspase-2
     $417,724

     award amount

2. Trejo, Joann

   Leads 2 awards · $1,954,034

   • 5K12GM068524-20Department: NIH department code

     San Diego IRACDA Scholars Program
     $1,489,032

     award amount
   • 5R35GM127121-05Department: NIH department code

     Cell Signaling by Protease-activated G Protein-coupled Receptors
     $465,002

     award amount

3. Tukey, Robert H

   Leads 2 awards · $1,628,408

   • 3P42ES010337-20S1Department: NIH department code

     Harnessing Technological Innovation and Community-Engaged Implementation Science to Optimize COVID-19 Testing for Women and Children in Underserved Communities
     $1,193,908

     award amount
   • 1R21ES034630-01Department: NIH department code

     APOB48 downregulation is the causing factor in mediating iAs-induced lipid accumulation in enterocytes
     $434,500

     award amount

4. Chi, Neil C

   Leads 2 awards · $1,482,940

   • 5T32GM007198-48Department: NIH department code

     Medical Scientist Training Program
     $1,368,868

     award amount
   • 3T32GM007198-48S1Department: NIH department code

     Medical Scientist Training Program
     $114,072

     award amount

5. Brown, Joan Heller

   Leads 3 awards · $1,475,541

   • 5T32GM007752-44Department: NIH department code

     Graduate Training in Cellular and Molecular Pharmacology
     $703,712

     award amount
   • 5R01HL145459-04Department: NIH department code

     Cardiomyocyte CaM kinase II as a driver of cardiac inflammation and remodeling
     $395,000

     award amount
   • 5R01CA218859-05Department: NIH department code

     RhoA and GPCR mediated transcriptional activation regulates glioblastoma
     $376,829

     award amount

6. Schoeneberg, Johannes

   Leads 1 award · $1,422,000

   • 1DP2GM150022-01Department: NIH department code

     Decode Mitochondrial Morphology Dynamics to Predict Cell Fate Decisions
     $1,422,000

     award amount

7. Gutkind, Jorge Silvio

   Leads 3 awards · $1,396,983

   • 2R01DE026644-06Department: NIH department code

     Targeting Signaling Vulnerabilities for Oral Cancer Prevention
     $475,111

     award amount
   • 5R01DE026870-05Department: NIH department code

     Targeting the EGFR-PI3K/mTOR Signaling Circuitry: A Network-Based Approach for Oral Cancer Precision Therapy
     $462,426

     award amount
   • 5R25CA221779-04Department: NIH department code

     Multidisciplinary Educational Approach to Reducing Cancer Disparities
     $459,446

     award amount

8. Zhang, Jin

   Leads 2 awards · $1,353,507

   • 2R35CA197622-08A1Department: NIH department code

     Live-cell Activity Architecture in Cancer
     $948,000

     award amount
   • 5R01DK073368-17Department: NIH department code

     Mechanisms of Compartmentalized cAMP Signaling
     $405,507

     award amount

9. Newton, Alexandra C.

   Leads 2 awards · $1,312,873

   • 2R35GM122523-06Department: NIH department code

     Molecular Mechanisms of Cell Signaling
     $659,856

     award amount
   • 5R01NS120725-02Department: NIH department code

     Structural and Molecular Mechanisms for Dysregulation of Protein Kinase C Gamma in Cerebellar Ataxia
     $653,017

     award amount

10. Handel, Tracy M

    Leads 3 awards · $1,175,264

    • 5R01AI161880-02Department: NIH department code

      It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12
      $682,876

      award amount
    • 5R01GM136202-03Department: NIH department code

      Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2
      $465,027

      award amount
    • 3R01GM136202-03S1Department: NIH department code

      Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2
      $27,361

      award amount

11. Reznik, Vivian

    Leads 4 awards · $1,174,280

    • 5R25HL145817-04Department: NIH department code

      UCSD PRIDE Faculty Development Program in Cardiovascular Sciences
      $469,800

      award amount
    • 5R25AI147376-03Department: NIH department code

      UC San Diego RAPID Faculty Development Program in Infectious Diseases
      $350,412

      award amount
    • 5R25NS117367-03Department: NIH department code

      San Diego Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Program
      $264,068

      award amount
    • 1R25GM146014-01Department: NIH department code

      Building a Respectful, Inclusive Culture
      $90,000

      award amount

12. Gustafsson, Asa B.

    Leads 2 awards · $1,047,826

    • 5R01HL155281-02Department: NIH department code

      Secretion of mitochondria as a cellular quality control mechanism
      $565,706

      award amount
    • 5R01HL157265-02Department: NIH department code

      Autophagy and Megamitochondria in Cardiac Aging and Heart Failure
      $482,120

      award amount

13. Taylor, Susan S.

    Leads 4 awards · $1,044,970

    • 5R35GM130389-04Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $584,349

      award amount
    • 3R35GM130389-04S2Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $329,168

      award amount
    • 3R35GM130389-04S1Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $80,377

      award amount
    • 3R35GM130389-04S3Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $51,076

      award amount

14. Gonzalez, David J

    Leads 2 awards · $934,999

    • 1R01DK131005-01A1Department: NIH department code

      Microbiome Driven Proteolysis as a Contributing Factor to Severity of Ulcerative Colitis Disease Activity
      $539,999

      award amount
    • 5R01AI148417-03Department: NIH department code

      Contribution of the peptidome to CA-MRSA virulence
      $395,000

      award amount

15. Evans, Sylvia M

    Leads 1 award · $869,000

    • 5R35HL144984-04Department: NIH department code

      Renewing the heart: cardiomyocyte cell cycle regulation
      $869,000

      award amount

16. Guan, Kun-Liang

    Leads 2 awards · $785,917

    • 1R01CA268179-01Department: NIH department code

      Functional interplay between Hippo and estrogen receptor ESR1
      $434,399

      award amount
    • 5R01GM051586-27Department: NIH department code

      Protein phosphorylation and growth factor function
      $351,518

      award amount

17. Yang, Jing

    Leads 3 awards · $771,185

    • 5R01CA236386-04Department: NIH department code

      Apical-basal polarity in tumor progression and metastasis
      $369,990

      award amount
    • 2R01CA174869-06A1Department: NIH department code

      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $363,773

      award amount
    • 3R01CA174869-06A1S1Department: NIH department code

      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $37,422

      award amount

18. Hook, Vivian Y. H

    Leads 1 award · $731,835

    • 5R01NS109075-04Department: NIH department code

      Development of Molecular Probe Inhibitors of Pathogenic, Cytosolic Cathespin B in Traumatic Brain Injury and Alzheimers Disease Neurodegeneration
      $731,835

      award amount

19. El-Khoueiry, Anthony Boutros

    Leads 1 award · $725,319

    • 5U01AA027681-05Department: NIH department code

      Immunosuppressive mechanisms responsible for development of non-viral liver cancer and control of its response to immune checkpoint inhibitors
      $725,319

      award amount

20. Hernandez, Inmaculada

    Leads 2 awards · $668,041

    • 5R01HL157051-02Department: NIH department code

      Pandemic Disruptions of Atrial Fibrillation Care
      $508,338

      award amount
    • 5K01HL142847-05Department: NIH department code

      Patient and System-Level Determinants of Oral Anticoagulation Use in Atrial Fibrillation
      $159,703

      award amount

21. Wang, Yingxiao

    Leads 1 award · $649,143

    • 1R01CA262815-01A1Department: NIH department code

      Ultrasensitive kinase biosensors for multiplex imaging of coordinated spatiotemporal signaling in cancer-immune interactions
      $649,143

      award amount

22. Donoghue, Daniel J

    Leads 1 award · $643,653

    • 5T32CA009523-35Department: NIH department code

      Contemporary Approaches to Cancer Cell Signaling and Communication
      $643,653

      award amount

23. Aplin, Andrew Eric

    Leads 1 award · $535,362

    • 5R01CA257505-02Department: NIH department code

      Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma
      $535,362

      award amount

24. Dennis, Edward A

    Leads 2 awards · $533,295

    • 5R35GM139641-02Department: NIH department code

      Action of Lipolytic Enzymes
      $402,900

      award amount
    • 3R35GM139641-02S1Department: NIH department code

      Action of Lipolytic Enzymes
      $130,395

      award amount

25. Dorrestein, Pieter C

    Leads 2 awards · $514,571

    • 1R03OD034493-01Department: NIH department code

      Cross Repository Metabolomics Data and Workflow Integration
      $302,764

      award amount
    • 1U24DK133658-01Department: NIH department code

      Collaborative Microbial Metabolite Center
      $211,807

      award amount

26. Cohen, Ezra

    Leads 1 award · $489,974

    • 5R01CA247551-03Department: NIH department code

      Co-targeting the HER3 oncogenic signaling circuitry and PD-1 as a novel multimodal precision immunotherapy for HNSCC
      $489,974

      award amount

27. Kobilka, Brian K

    Leads 1 award · $476,217

    • 5R01GM083118-15Department: NIH department code

      Structure and dynamics of G protein coupled receptor-G protein complexes
      $476,217

      award amount

28. Wang, Dong

    Leads 1 award · $474,423

    • 2R01GM102362-10Department: NIH department code

      Molecular Mechanisms for DNA Damage Processing by Transcription Machinery
      $474,423

      award amount

29. Martinez, Maria Elena

    Leads 1 award · $474,000

    • 1U54CA272220-01Department: NIH department code

      UC San Diego FIRST Program
      $474,000

      award amount

30. Radic, Zoran

    Leads 2 awards · $456,687

    • 1R21NS120839-01A1Department: NIH department code

      Refined uncharged Bis-Oximes for Rapid CNS Reactivation of OP-Inhibited hAChE.
      $246,853

      award amount
    • 1R21NS120884-01A1Department: NIH department code

      In Vivo Efficacy of Novel Uncharged Bis-Oximes in OP Poisoning Treatment
      $209,834

      award amount

31. Chang, Geoffrey A

    Leads 1 award · $434,500

    • 1R21AG079330-01Department: NIH department code

      Synthetically-evolved and engineered Nanobodies selective for Cb isoforms of PKA
      $434,500

      award amount

32. Daneman, Richard

    Leads 1 award · $434,500

    • 1R21AG077148-01Department: NIH department code

      Neural activity dependent regulation of vascular: implications for Alzheimers disease
      $434,500

      award amount

33. Joiner, William J

    Leads 1 award · $434,500

    • 1R21NS123690-01A1Department: NIH department code

      Multiplexed RNAscope imaging of gene expression in targeted cells across the fly brain
      $434,500

      award amount

34. Debnath, Anjan

    Leads 2 awards · $428,575

    • 1R21EY034294-01Department: NIH department code

      A machine learning-based screen of marine natural products to identify new leads for the treatment of Acanthamoeba eye infection
      $237,000

      award amount
    • 5R21EY032601-02Department: NIH department code

      Latrunculin B as a new drug lead for the treatment of Acanthamoeba keratitis
      $191,575

      award amount

35. Munji, Roeben

    Leads 1 award · $395,000

    • 1R01MH129979-01A1Department: NIH department code

      Endothelial monoamine neurotransmitter metabolism at the blood-brain barrier
      $395,000

      award amount

36. Huber, Gary Alexander

    Leads 1 award · $385,760

    • 5R01GM031749-41Department: NIH department code

      Theory of Biomolecular Diffusion
      $385,760

      award amount

37. Abagyan, Ruben

    Leads 1 award · $384,321

    • 5R35GM131881-04Department: NIH department code

      Addressing biomedical challenges with computational mechanics and big data
      $384,321

      award amount

38. Bandeira, Nuno

    Leads 1 award · $323,945

    • 5R01LM013115-04Department: NIH department code

      MassIVE.quant: a curated and scalable community resource for quantitative proteomics
      $323,945

      award amount

39. Adams, Joseph

    Leads 1 award · $323,225

    • 5R01GM067969-18Department: NIH department code

      Regulatory Pathways of SR Protein Kinases
      $323,225

      award amount

40. Reya, Tannishtha

    Leads 2 awards · $296,248

    • 5R35CA197699-08Department: NIH department code

      Molecular strategies for early detection and targeting of cancer
      $296,247

      award amount
    • 3R35CA197699-08S1Department: NIH department code

      Molecular strategies for early detection and targeting of cancer
      $1

      award amount

41. Caffrey, Conor

    Leads 1 award · $237,000

    • 1R21AI171824-01Department: NIH department code

      The catalytic core of the proteasome as a drug target to treat Human African Trypanosomiasis
      $237,000

      award amount

42. O'Donoghue, Anthony John

    Leads 1 award · $231,823

    • 1R21CA256460-01A1Department: NIH department code

      Tumor-specific drug activation by pericellular proteases
      $231,823

      award amount

43. Ballatore, Carlo

    Leads 1 award · $197,500

    • 5R21AI156554-02Department: NIH department code

      Development of thiophen-2-yl-phenylpyrimidines for treatment of schistosomiasis
      $197,500

      award amount

44. Kufareva, Irina

    Leads 1 award · $197,500

    • 5R21AI156662-02Department: NIH department code

      Spatiotemporally resolved architecture of G protein signaling downstream of CXCR4, the driver of lymphocyte migration
      $197,500

      award amount

45. Garcia-Pak, Iris Haleakala

    Leads 1 award · $39,660

    • 5F30DA054776-02Department: NIH department code

      What is the role of blood-brain-barrier regional specificity in the nucleus accumbens?
      $39,660

      award amount

46. Schafer, Christopher T

    Leads 1 award · $25,075

    • 5F32GM137505-03Department: NIH department code

      Biased agonsim of CXCL12 stimulation of the atypical and classical receptors, ACKR3 and CXCR4
      $25,075

      award amount