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FY2025 NIH awards · Principal investigators

Pharmacology at University of California, San Diego

La Jolla, CA

Funding
$35.7M
$35,745,068
Awards
69
FY2025 NIH awards in Pharmacology
Principal investigators
50
34 lead a grant here, 16 co-investigators
Department rank
#2
of 127 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pharmacology row of the University of California, San Diego page.

Leads a grant in this department

34 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Joann Trejo

    Leads 8 awards · $3,611,291

    • 5K12GM068524-23Department: NIH department code
      San Diego IRACDA Scholars Program
      $1,511,033
      award amount
    • 5R01HL163931-03Department: NIH department code
      Endothelial Cytoprotective Signaling by Activated Protein C/Protease-activated Receptor-1
      $603,094
      award amount
    • 5R35GM127121-08Department: NIH department code
      Cell signaling by G protein-coupled receptors
      $530,880
      award amount
    • 2R25AI147376-06Department: NIH department code
      UC San Diego Raising Advancement and Parity for Infectious Disease Researchers (RAPID) Faculty Development Program

      Principal investigators: Joann Trejo (contact PI), Adriana H Tremoulet

      $379,080
      award amount
    • 5R25HL145817-07Department: NIH department code
      UCSD Future Faculty of Cardiovascular Sciences (FOCUS)

      Principal investigators: Joann Trejo (contact PI), Robert Scott Ross

      $342,360
      award amount
    • 3R01HL163931-03S1Department: NIH department code
      Endothelial Cytoprotective Signaling by Activated Protein C/Protease-activated Receptor-1
      $114,583
      award amount
    • 3R35GM127121-08S1Department: NIH department code
      Cell signaling by G protein-coupled receptors
      $97,696
      award amount
    • 3R35GM127121-07S1Department: NIH department code
      Cell signaling by G protein-coupled receptors
      $32,565
      award amount

  2. Vivian Y. H Hook

    Leads 1 award · $3,138,871

    • 1RF1AG095193-01Department: NIH department code
      Human neuropeptide transmitter systems are dysregulated in Alzheimer's disease pathogenesis
      $3,138,871
      award amount

  3. Jin Zhang

    Leads 4 awards · $2,486,130

    • 5R35CA197622-11Department: NIH department code
      Live-cell Activity Architecture in Cancer
      $948,000
      award amount
    • 5R01CA262815-04Department: NIH department code
      Ultrasensitive kinase biosensors for multiplex imaging of coordinated spatiotemporal signaling in cancer-immune interactions

      Principal investigators: Jin Zhang (contact PI), Yingxiao Wang

      $649,143
      award amount
    • 5R01DE030497-05Department: NIH department code
      Signal Transduction by PI3K/mTOR

      Principal investigators: Jin Zhang (contact PI), Jorge Silvio Gutkind

      $483,480
      award amount
    • 5R01DK073368-20Department: NIH department code
      Mechanisms of Compartmentalized cAMP Signaling
      $405,507
      award amount

  4. Conor Caffrey

    Leads 1 award · $2,250,355

    • 5U01AG088051-02Department: NIH department code
      Development of a MT-stabilizing agent for the treatment of tauopathies

      Principal investigators: Conor Caffrey (contact PI), Kurt R. Brunden

      $2,250,355
      award amount

    Also a principal investigator on 1R21AI188258-01A1, led by Anthony John O'Donoghue.

  5. Jorge Silvio Gutkind

    Leads 4 awards · $2,066,187

    • 5R01DE033909-02Department: NIH department code
      Reprogramming the Tumor Immune Microenvironment with Chemokines to Potentiate Immune Oncology Treatments in Oral Cancer

      Principal investigators: Jorge Silvio Gutkind (contact PI), Tracy M Handel

      $585,606
      award amount
    • 5R01CA257505-05Department: NIH department code
      Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma

      Principal investigators: Jorge Silvio Gutkind (contact PI), Andrew Eric Aplin

      $522,110
      award amount
    • 1R01DE035393-01Department: NIH department code
      Targeting Systems Vulnerabilities in the EGFR/HER3/HER2 Oncogenic Signaling Circuitry: New Precision Therapies for Oral Cancer

      Principal investigators: Jorge Silvio Gutkind (contact PI), Assuntina Gesualda Sacco

      $483,360
      award amount
    • 5R01DE026644-09Department: NIH department code
      Targeting Signaling Vulnerabilities for Oral Cancer Prevention

      Principal investigators: Jorge Silvio Gutkind (contact PI), Scott M Lippman

      $475,111
      award amount

    Also a principal investigator on 5R01DE030497-05, led by Jin Zhang.

  6. Jing Yang

    Leads 5 awards · $1,960,803

    • 5T32CA009523-38Department: NIH department code
      Contemporary Approaches to Cancer Cell Signaling and Communication

      Principal investigators: Jing Yang (contact PI), Daniel J Donoghue

      $674,370
      award amount
    • 3R01CA174869-09S2Department: NIH department code
      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $437,250
      award amount
    • 5R01CA268179-04Department: NIH department code
      Functional interplay between Hippo and estrogen receptor ESR1
      $434,399
      award amount
    • 5R01CA174869-09Department: NIH department code
      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $363,773
      award amount
    • 3R01CA174869-09S1Department: NIH department code
      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $51,011
      award amount

  7. Richard Daneman

    Leads 4 awards · $1,805,194

    • 1R01AG090641-01Department: NIH department code
      Role of Sox18 in neurovascular dysfunction in Alzheimer's disease
      $772,581
      award amount
    • 1R21AG090974-01Department: NIH department code
      Neurovascular protein lifetime in health, aging and Alzheimer's disease
      $437,875
      award amount
    • 5R01NS119615-05Department: NIH department code
      How do CNS fibroblasts regulate the response to neuroinflammation?
      $397,238
      award amount
    • 5R21NS137131-02Department: NIH department code
      Cross species molecular analysis of glial and endothelial blood-brain barriers
      $197,500
      award amount

  8. Robert H Tukey

    Leads 2 awards · $1,434,842

    • 1R01ES036571-01A1Department: NIH department code
      Effects of early life Triclosan exposure through lactation on the gut-liver axis and its implications in the development of steatotic liver disease in adults

      Principal investigators: Robert H Tukey (contact PI), Michael Karin

      $794,841
      award amount
    • 5R01DK136599-03Department: NIH department code
      Severe neonatal hyperbilirubinemia (SNH) and the expression of UDP-glucuronosyltransferase 1A1 (UGT1A1) play key roles in the development of necrotizing enterocolitis (NEC)
      $640,001
      award amount

  9. Pieter C Dorrestein

    Leads 2 awards · $1,396,423

    • 5R01DK136117-03Department: NIH department code
      Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules
      $729,823
      award amount
    • 5U24DK133658-04Department: NIH department code
      Collaborative Microbial Metabolite Center
      $666,600
      award amount

  10. Alexandra C. Newton

    Leads 2 awards · $1,312,873

    • 5R35GM122523-09Department: NIH department code
      Molecular Mechanisms of Cell Signaling
      $659,856
      award amount
    • 5R01NS120725-05Department: NIH department code
      Structural and Molecular Mechanisms for Dysregulation of Protein Kinase C Gamma in Cerebellar Ataxia

      Principal investigators: Alexandra C. Newton (contact PI), Susan S. Taylor

      $653,017
      award amount

  11. Michael Karin

    Leads 5 awards · $1,294,658

    • 5R37AI043477-28Department: NIH department code
      NF-kappaB and Mitochondrial Signals as Positive and Negative Regulators of Inflammation
      $360,524
      award amount
    • 5R01DK120714-07Department: NIH department code
      Control of Lipogenesis and Hepatic Steatosis by Caspase-2
      $340,748
      award amount
    • 5R01DK133448-04Department: NIH department code
      The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism

      Principal investigators: Michael Karin (contact PI), Jun Hee Lee

      $305,121
      award amount
    • 5R01CA285997-02Department: NIH department code
      Collagen fibers and fragments regulate pancreatic cancer metabolism and growth.

      Principal investigators: Michael Karin (contact PI), David A. Brenner

      $178,265
      award amount
    • 3U01CA274295-03S1Department: NIH department code
      Regulation of PDAC metabolism and immunity by collagen and its cleavage products

      Principal investigators: Michael Karin (contact PI), Andrew M Lowy, Robert F. Schwabe

      $110,000
      award amount

    Also a principal investigator on 1R01ES036571-01A1, led by Robert H Tukey.

  12. Johannes Schoeneberg

    Leads 2 awards · $1,253,499

    • 4DP2GM150022-02Department: NIH department code
      Decode Mitochondrial Morphology Dynamics to Predict Cell Fate Decisions
      $957,500
      award amount
    • 5R01GM148765-03Department: NIH department code
      Modeling and Analysis of the Spatio-Temporal Dynamics of the Mitochondrial Network
      $295,999
      award amount

  13. Michael K. Gilson

    Leads 3 awards · $1,251,163

    • 1R01GM158907-01Department: NIH department code
      Innovative drug design technologies from computational mapping of energy, entropy, and free energy in proteins and protein-ligand systems
      $638,334
      award amount
    • 5R24GM144232-04Department: NIH department code
      BindingDB: An Open Knowledgebase of Protein-Small Molecule Interactions
      $571,960
      award amount
    • 3R24GM144232-03S1Department: NIH department code
      BindingDB: An Open Knowledgebase of Protein-Small Molecule Interactions
      $40,869
      award amount

  14. Juliana Idoyaga

    Leads 2 awards · $929,869

    • 5R01AI158808-06Department: NIH department code
      Transitional dendritic cells: identifying the origin and role of a novel innate immune population during viral infection
      $534,869
      award amount
    • 5R01DK131500-06Department: NIH department code
      From stomach tissue to cellular mechanisms: unraveling the role of mononuclear phagocytes in the pathophysiology of gastroparesis
      $395,000
      award amount

  15. Dong Wang

    Leads 2 awards · $878,228

    • 5R01GM102362-13Department: NIH department code
      Molecular Mechanisms for DNA Damage Processing by Transcription Machinery
      $474,422
      award amount
    • 5R01GM148476-03Department: NIH department code
      Recognition of Synthetic Unnatural Base Pairs by RNA Polymerase
      $403,806
      award amount

  16. Sylvia M Evans

    Leads 1 award · $869,000

    • 5R35HL144984-07Department: NIH department code
      Renewing the heart: cardiomyocyte cell cycle regulation
      $869,000
      award amount

  17. David J Gonzalez

    Leads 1 award · $791,820

    • 1U24CA299590-01Department: NIH department code
      Advancing METASPACE and Spatial Metabolomics for Cancer Research
      $791,820
      award amount

  18. Roeben Munji

    Leads 1 award · $790,000

    • 4RF1MH129979-04Department: NIH department code
      Endothelial monoamine neurotransmitter metabolism at the blood-brain barrier
      $790,000
      award amount

  19. Andrew S Mendiola

    Leads 2 awards · $743,145

    • 1R01NS144158-01Department: NIH department code
      Mechanisms of pathogenic microglial populations in CNS inflammation
      $521,839
      award amount
    • 5R00NS126707-04Department: NIH department code
      Epigenomic regulation of oxidative stress-producing innate immunity in neuroinflammation
      $221,306
      award amount

  20. Geoffrey A Chang

    Leads 2 awards · $718,498

  21. Nuno Bandeira

    Leads 1 award · $704,894

    • 5R24GM148372-03Department: NIH department code
      Global proteomics mass spectrometry data sharing infrastructure
      $704,894
      award amount

  22. Tracy M Handel

    Leads 1 award · $649,061

    • 5R01AI161880-05Department: NIH department code
      It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12

      Principal investigators: Tracy M Handel (contact PI), Irina Kufareva

      $649,061
      award amount

    Also a principal investigator on 5R01DE033909-02, led by Jorge Silvio Gutkind; 5T32GM153123-02, led by Joan Heller Brown.

  23. Susan S. Taylor

    Leads 1 award · $632,000

    • 5R35GM130389-08Department: NIH department code
      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $632,000
      award amount

    Also a principal investigator on 5R01NS120725-05, led by Alexandra C. Newton.

  24. Anthony John O'Donoghue

    Leads 1 award · $438,500

    • 1R21AI188258-01A1Department: NIH department code
      New tools to facilitate drug discovery for pathogen proteasomes

      Principal investigators: Anthony John O'Donoghue (contact PI), Conor Caffrey

      $438,500
      award amount

  25. Padmini Rangamani

    Leads 1 award · $437,709

    • 1R35GM158446-01Department: NIH department code
      Biophysical modeling of inward and outward membrane curvature generation
      $437,709
      award amount

  26. Shigeki Miyamoto

    Leads 1 award · $437,375

    • 1R21AG095645-01Department: NIH department code
      NEK7 suppresses inflammation in the aging heart through regulation of RNA binding proteins
      $437,375
      award amount

  27. Edward A Dennis

    Leads 1 award · $402,900

    • 5R35GM139641-05Department: NIH department code
      Action of Lipolytic Enzymes
      $402,900
      award amount

  28. Anjan Debnath

    Leads 2 awards · $391,997

    • 5R21EY036216-02Department: NIH department code
      Sterol Biosynthesis Inhibitors as Drug Leads for the Treatment of Acanthamoeba Eye Infection
      $197,500
      award amount
    • 5R21AI171538-02Department: NIH department code
      Development of brain-penetrant drugs targeting N. fowleri primary amoebic meningoencephalitis (PAM)
      $194,497
      award amount

  29. Joan Heller Brown

    Leads 1 award · $370,408

    • 5T32GM153123-02Department: NIH department code
      Cellular and Molecular Pharmacology Training Program

      Principal investigators: Joan Heller Brown (contact PI), Tracy M Handel

      $370,408
      award amount

  30. Haoqi Nina Zhao

    Leads 1 award · $95,000

    • 1K99ES037746-01Department: NIH department code
      Mapping Xenobiotic Metabolism by the Human Gut Microbiome
      $95,000
      award amount

  31. Benjamin Domenic Gastfriend

    Leads 1 award · $75,520

    • 5F32NS134680-02Department: NIH department code
      Development of Tissue-Specific Properties in Central Nervous System Mural Cells
      $75,520
      award amount

  32. Evan Yu-An Wen

    Leads 1 award · $42,596

    • 1F31HL182106-01Department: NIH department code
      Spatial diversity of GPCR-mediated ERK signaling and its role in cardiovascular disease
      $42,596
      award amount

  33. Anne Lyons

    Leads 1 award · $42,319

    • 5F31HL176051-02Department: NIH department code
      Illuminating ER Lumen AMPK Dynamics for Maintaining Vascular Homeostasis via ACE2
      $42,319
      award amount

  34. Stefanie Jill Hodapp

    Leads 1 award · $41,940

    • 5F31HL168916-03Department: NIH department code
      Regulation of Protein Kinase C Theta by Phosphorylation
      $41,940
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.