Pharmacology at University of California, San Diego

Leads a grant in this department

47 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Martinez, Maria Elena

   Leads 1 award · $5,174,500

   • 5U54CA272220-02Department: NIH department code

     UC San Diego FIRST Program
     $5,174,500

     award amount

2. Karin, Michael

   Leads 6 awards · $3,466,605

   • 5U01CA274295-02Department: NIH department code

     Regulation of PDAC metabolism and immunity by collagen and its cleavage products
     $955,015

     award amount
   • 5R01DK133448-02Department: NIH department code

     The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism
     $684,436

     award amount
   • 1R01CA281784-01Department: NIH department code

     A new mouse model for studying the pathogenesis and immunobiology of intrahepatic cholangiocarcinoma and improving its immunotherapy
     $563,902

     award amount
   • 2R01DK120714-05A1Department: NIH department code

     Control of Lipogenesis and Hepatic Steatosis by Caspase-2
     $546,309

     award amount
   • 5R01CA234128-05Department: NIH department code

     Highly penetrant and immunogenic mouse models of non-viral HCC that are suitable for evaluation of immune checkpoint inhibitors
     $542,443

     award amount
   • 3U01CA274295-02S1Department: NIH department code

     The effect of cancer cell produced collagen 1 homotrimers on DDR1 signaling activation by microenvironmental collagen 1 fragments.
     $174,500

     award amount

3. Trejo, Joann

   Leads 5 awards · $2,685,423

   • 5K12GM068524-21Department: NIH department code

     San Diego IRACDA Scholars Program
     $1,407,153

     award amount
   • 1R01HL163931-01A1Department: NIH department code

     Endothelial Cytoprotective Signaling by Activated Protein C/Protease-activated Receptor-1
     $604,713

     award amount
   • 2R35GM127121-06Department: NIH department code

     Cell signaling by G protein-coupled receptors
     $530,880

     award amount
   • 3K12GM068524-21S1Department: NIH department code

     San Diego IRACDA Scholars Program
     $92,880

     award amount
   • 3R01HL163931-01A1S1Department: NIH department code

     Endothelial Cytoprotective Signaling by Activated Protein C/Protease-activated Receptor-1
     $49,797

     award amount

4. Daneman, Richard

   Leads 2 awards · $2,086,029

   • 1RF1AG078241-01A1Department: NIH department code

     Neurovascular circadian oscillation in health and Alzheimer's disease
     $1,966,145

     award amount
   • 3R21AG077148-01S1Department: NIH department code

     Neural activity dependent regulation of vascular: implications for Alzheimers disease
     $119,884

     award amount

5. Duggan, Brendan Michael

   Leads 1 award · $1,802,603

   • 1S10OD032266-01A1Department: NIH department code

     600 MHz NMR spectrometer with 1.7mm micro-cryoprobe
     $1,802,603

     award amount

6. Chi, Neil C

   Leads 2 awards · $1,567,445

   • 5T32GM007198-49Department: NIH department code

     Medical Scientist Training Program
     $1,393,284

     award amount
   • 3T32GM007198-49S1Department: NIH department code

     Medical Scientist Training Program
     $174,161

     award amount

7. Dorrestein, Pieter C

   Leads 2 awards · $1,404,544

   • 5U24DK133658-02Department: NIH department code

     Collaborative Microbial Metabolite Center
     $709,891

     award amount
   • 1R01DK136117-01Department: NIH department code

     Reverse Metabolomics for the Discovery of Disease Associated Microbial Molecules
     $694,653

     award amount

8. Zhang, Jin

   Leads 2 awards · $1,334,547

   • 5R35CA197622-09Department: NIH department code

     Live-cell Activity Architecture in Cancer
     $929,040

     award amount
   • 5R01DK073368-18Department: NIH department code

     Mechanisms of Compartmentalized cAMP Signaling
     $405,507

     award amount

9. Newton, Alexandra C.

   Leads 3 awards · $1,326,344

   • 5R35GM122523-07Department: NIH department code

     Molecular Mechanisms of Cell Signaling
     $659,856

     award amount
   • 5R01NS120725-03Department: NIH department code

     Structural and Molecular Mechanisms for Dysregulation of Protein Kinase C Gamma in Cerebellar Ataxia
     $653,017

     award amount
   • 3R35GM122523-06S1Department: NIH department code

     Molecular Mechanisms of Cell Signaling
     $13,471

     award amount

10. Gutkind, Jorge Silvio

    Leads 3 awards · $1,317,092

    • 5R01CA247551-04Department: NIH department code

      Co-targeting the HER3 oncogenic signaling circuitry and PD-1 as a novel multimodal precision immunotherapy for HNSCC
      $489,974

      award amount
    • 5R01DE026644-07Department: NIH department code

      Targeting Signaling Vulnerabilities for Oral Cancer Prevention
      $475,111

      award amount
    • 5R25CA221779-05Department: NIH department code

      Multidisciplinary Educational Approach to Reducing Cancer Disparities
      $352,007

      award amount

11. Yang, Jing

    Leads 4 awards · $1,237,992

    • 5R01CA268179-02Department: NIH department code

      Functional interplay between Hippo and estrogen receptor ESR1
      $425,711

      award amount
    • 5R01CA236386-05Department: NIH department code

      Apical-basal polarity in tumor progression and metastasis
      $369,990

      award amount
    • 5R01CA174869-07Department: NIH department code

      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $356,497

      award amount
    • 3R01CA174869-07S1Department: NIH department code

      Regulation of Tumor Invasion and Metastasis by Matrix Stiffness
      $85,794

      award amount

12. Handel, Tracy M

    Leads 3 awards · $1,159,294

    • 5R01AI161880-03Department: NIH department code

      It's a tug of war: structure, consequences, and inhibition of CXCR4 and ACKR3 responses to lymphocyte chemoattractant CXCL12
      $671,571

      award amount
    • 5R01GM136202-04Department: NIH department code

      Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2
      $460,395

      award amount
    • 3R01GM136202-04S1Department: NIH department code

      Signaling circuits that drive cell movement and ligand scavenging by chemokine receptor CCR2
      $27,328

      award amount

13. Brown, Joan Heller

    Leads 2 awards · $1,070,491

    • 5T32GM007752-45Department: NIH department code

      Graduate Training in Cellular and Molecular Pharmacology
      $718,973

      award amount
    • 5R01GM051586-28Department: NIH department code

      Protein phosphorylation and growth factor function
      $351,518

      award amount

14. Reznik, Vivian

    Leads 4 awards · $1,048,196

    • 5R25AI147376-04Department: NIH department code

      UC San Diego RAPID Faculty Development Program in Infectious Diseases
      $350,154

      award amount
    • 5R25HL145817-05Department: NIH department code

      UCSD PRIDE Faculty Development Program in Cardiovascular Sciences
      $347,287

      award amount
    • 5R25NS117367-04Department: NIH department code

      San Diego Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Program
      $261,330

      award amount
    • 5R25GM146014-02Department: NIH department code

      Building a Respectful, Inclusive Culture
      $89,425

      award amount

15. Gustafsson, Asa B.

    Leads 2 awards · $1,048,097

    • 5R01HL155281-03Department: NIH department code

      Secretion of mitochondria as a cellular quality control mechanism
      $565,706

      award amount
    • 5R01HL157265-03Department: NIH department code

      Autophagy and Megamitochondria in Cardiac Aging and Heart Failure
      $482,391

      award amount

16. Wang, Dong

    Leads 3 awards · $1,013,428

    • 5R01GM102362-11Department: NIH department code

      Molecular Mechanisms for DNA Damage Processing by Transcription Machinery
      $474,420

      award amount
    • 1R01GM148476-01Department: NIH department code

      Recognition of Synthetic Unnatural Base Pairs by RNA Polymerase
      $403,349

      award amount
    • 3R01GM102362-11S1Department: NIH department code

      Molecular Mechanisms for DNA Damage Processing by Transcription Machinery
      $135,659

      award amount

17. Gonzalez, David J

    Leads 2 awards · $934,998

    • 5R01DK131005-02Department: NIH department code

      Microbiome Driven Proteolysis as a Contributing Factor to Severity of Ulcerative Colitis Disease Activity
      $539,998

      award amount
    • 5R01AI148417-04Department: NIH department code

      Contribution of the peptidome to CA-MRSA virulence
      $395,000

      award amount

18. Dore, Kim Bohemie

    Leads 1 award · $908,983

    • 1R56AG082903-01Department: NIH department code

      Aberrant Protein Kinase C Signaling in Alzheimer's Disease
      $908,983

      award amount

19. Evans, Sylvia M

    Leads 1 award · $869,000

    • 5R35HL144984-05Department: NIH department code

      Renewing the heart: cardiomyocyte cell cycle regulation
      $869,000

      award amount

20. Idoyaga, Juliana

    Leads 2 awards · $862,792

    • 7R01AI158808-04Department: NIH department code

      Transitional dendritic cells: identifying the origin and role of a novel innate immune population during viral infection
      $469,293

      award amount
    • 7R01DK131500-04Department: NIH department code

      From stomach tissue to cellular mechanisms: unraveling the role of mononuclear phagocytes in the pathophysiology of gastroparesis
      $393,499

      award amount

21. Bandeira, Nuno

    Leads 1 award · $730,979

    • 1R24GM148372-01Department: NIH department code

      Global proteomics mass spectrometry data sharing infrastructure
      $730,979

      award amount

22. Hook, Vivian Y. H

    Leads 1 award · $718,592

    • 5R01NS109075-05Department: NIH department code

      Development of Molecular Probe Inhibitors of Pathogenic, Cytosolic Cathespin B in Traumatic Brain Injury and Alzheimers Disease Neurodegeneration
      $718,592

      award amount

23. Donoghue, Daniel J

    Leads 1 award · $660,307

    • 5T32CA009523-36Department: NIH department code

      Contemporary Approaches to Cancer Cell Signaling and Communication
      $660,307

      award amount

24. Tukey, Robert H

    Leads 1 award · $640,001

    • 1R01DK136599-01Department: NIH department code

      Severe neonatal hyperbilirubinemia (SNH) and the expression of UDP-glucuronosyltransferase 1A1 (UGT1A1) play key roles in the development of necrotizing enterocolitis (NEC)
      $640,001

      award amount

25. Wang, Yingxiao

    Leads 1 award · $636,160

    • 5R01CA262815-02Department: NIH department code

      Ultrasensitive kinase biosensors for multiplex imaging of coordinated spatiotemporal signaling in cancer-immune interactions
      $636,160

      award amount

26. Taylor, Susan S.

    Leads 2 awards · $626,771

    • 2R35GM130389-06Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $334,596

      award amount
    • 5R35GM130389-05Department: NIH department code

      Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches
      $292,175

      award amount

27. Gilson, Michael K.

    Leads 1 award · $603,560

    • 5R24GM144232-02Department: NIH department code

      BindingDB: An Open Knowledgebase of Protein-Small Molecule Interactions
      $603,560

      award amount

28. Kobilka, Brian K

    Leads 2 awards · $541,788

    • 5R01GM083118-16Department: NIH department code

      Structure and dynamics of G protein coupled receptor-G protein complexes
      $472,743

      award amount
    • 3R01GM083118-16S1Department: NIH department code

      Structure and dynamics of G protein coupled receptor-G protein complexes
      $69,045

      award amount

29. Aplin, Andrew Eric

    Leads 1 award · $525,822

    • 5R01CA257505-03Department: NIH department code

      Targeting Systems Vulnerabilities in the Gαq/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma
      $525,822

      award amount

30. Hernandez, Inmaculada

    Leads 1 award · $505,596

    • 5R01HL157051-03Department: NIH department code

      Pandemic Disruptions of Atrial Fibrillation Care
      $505,596

      award amount

31. Dennis, Edward A

    Leads 1 award · $402,900

    • 5R35GM139641-03Department: NIH department code

      Action of Lipolytic Enzymes
      $402,900

      award amount

32. Munji, Roeben

    Leads 1 award · $395,000

    • 5R01MH129979-02Department: NIH department code

      Endothelial monoamine neurotransmitter metabolism at the blood-brain barrier
      $395,000

      award amount

33. Abagyan, Ruben

    Leads 1 award · $384,321

    • 5R35GM131881-05Department: NIH department code

      Addressing biomedical challenges with computational mechanics and big data
      $384,321

      award amount

34. Radic, Zoran

    Leads 2 awards · $348,503

    • 5R21NS120839-02Department: NIH department code

      Refined uncharged Bis-Oximes for Rapid CNS Reactivation of OP-Inhibited hAChE.
      $192,670

      award amount
    • 5R21NS120884-02Department: NIH department code

      In Vivo Efficacy of Novel Uncharged Bis-Oximes in OP Poisoning Treatment
      $155,833

      award amount

35. Adams, Joseph

    Leads 1 award · $322,705

    • 5R01GM067969-19Department: NIH department code

      Regulatory Pathways of SR Protein Kinases
      $322,705

      award amount

36. Schoeneberg, Johannes

    Leads 1 award · $295,999

    • 1R01GM148765-01Department: NIH department code

      Modeling and Analysis of the Spatio-Temporal Dynamics of the Mitochondrial Network
      $295,999

      award amount

37. Joiner, William J

    Leads 1 award · $237,000

    • 1R21AG080788-01Department: NIH department code

      The contribution of Ly6h to Alzheimers Disease
      $237,000

      award amount

38. Bui, Jack D

    Leads 1 award · $221,595

    • 1R21CA280794-01Department: NIH department code

      Optimization of CAR-Bacteria for Oral Cancer
      $221,595

      award amount

39. Caffrey, Conor

    Leads 1 award · $197,500

    • 5R21AI171824-02Department: NIH department code

      The catalytic core of the proteasome as a drug target to treat Human African Trypanosomiasis
      $197,500

      award amount

40. Debnath, Anjan

    Leads 1 award · $197,500

    • 5R21EY034294-02Department: NIH department code

      A machine learning-based screen of marine natural products to identify new leads for the treatment of Acanthamoeba eye infection
      $197,500

      award amount

41. O'Donoghue, Anthony John

    Leads 1 award · $177,630

    • 5R21CA256460-02Department: NIH department code

      Tumor-specific drug activation by pericellular proteases
      $177,630

      award amount

42. Chaim, Olga

    Leads 1 award · $79,000

    • 1R03NS131822-01Department: NIH department code

      Leveraging Gα12 signaling to treat glioblastoma
      $79,000

      award amount

43. Cavender, Chapin E

    Leads 1 award · $69,080

    • 1F32GM150240-01Department: NIH department code

      Developing a nucleic acid force field with direct chemical perception for computational modeling of nucleic acid therapeutics
      $69,080

      award amount

44. Garcia-Pak, Iris Haleakala

    Leads 1 award · $52,694

    • 5F30DA054776-03Department: NIH department code

      What is the role of blood-brain-barrier regional specificity in the nucleus accumbens?
      $52,694

      award amount

45. Sahan, Ayse Zisan

    Leads 1 award · $41,489

    • 1F31DE032886-01A1Department: NIH department code

      Spatial regulation of mechanistic target of rapamycin complex 1 (mTORC1) and its role in oral squamous cell carcinoma
      $41,489

      award amount

46. Harvey, Sean Sandas

    Leads 1 award · $40,287

    • 1F31AG084272-01Department: NIH department code

      The role of vascular lipids in Alzheimer's disease pathophysiology
      $40,287

      award amount

47. Hodapp, Stefanie Jill

    Leads 1 award · $40,096

    • 1F31HL168916-01Department: NIH department code

      Regulation of Protein Kinase C Theta by Phosphorylation
      $40,096

      award amount