Pharmacology at University of California, San Francisco

Leads a grant in this department

82 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Altman, Russ Biagio

   Leads 3 awards · $6,675,506

   • 2U01FD005978-06Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $6,358,865

     award amount
   • 3U01FD005978-05S2Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science
     $280,055

     award amount
   • 3U01FD005978-05S1Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science
     $36,586

     award amount

2. Krogan, Nevan J

   Leads 2 awards · $3,000,000

   • 5U19AI135990-04Department: NIH department code

     HPMI: Host Pathogen Mapping Initiative
     $2,000,000

     award amount
   • 3U19AI135990-04S1Department: NIH department code

     HPMI: Host Pathogen Mapping Initiative
     $1,000,000

     award amount

3. Ahituv, Nadav

   Leads 2 awards · $2,074,900

   • 3UM1HG009408-04S1Department: NIH department code

     Massively parallel reporter assays and genome editing of ENCODE predicted regulatory elements
     $1,409,478

     award amount
   • 5U01MH116438-04Department: NIH department code

     Massively parallel characterization of psychiatric disease associated regulatory elements in defined cell types
     $665,422

     award amount

4. Guo, Su

   Leads 5 awards · $1,866,405

   • 5R01GM132500-03Department: NIH department code

     Mechanisms that drive the variation of aversive behavior
     $534,783

     award amount
   • 1R21NS122053-01A1Department: NIH department code

     Single-cell transcriptomic analysis of sibling progenitors with differential Notch activity
     $444,125

     award amount
   • 1R01NS120219-01A1Department: NIH department code

     Mechanisms of renin-angiotensin signaling in programmed and insult-induced neuronal death
     $403,750

     award amount
   • 1R01NS120218-01A1Department: NIH department code

     Asymmetric Cell Division of Vertebrate Radial Glia Neural Progenitors
     $392,080

     award amount
   • 3R01GM132500-03S1Department: NIH department code

     Diversity Supplement Extension
     $91,667

     award amount

5. Gartner, Zev Jordan

   Leads 4 awards · $1,865,793

   • 5U01CA244109-02Department: NIH department code

     Understanding breast cancer progression as a defect in the mechanics of tissue self-organization
     $577,726

     award amount
   • 5R01DK126376-02Department: NIH department code

     The physical and molecular mechanisms of intestinal villus morphogenesis and repair
     $570,475

     award amount
   • 1R33CA247744-01A1Department: NIH department code

     Universal Sample Multiplexing for Single Cell Analysis
     $398,629

     award amount
   • 5R01GM135462-03Department: NIH department code

     MULTIseq: multiplexing massively parallel single cell transcriptional analysis across time, space, and conditions
     $318,963

     award amount

6. Huang, Bo

   Leads 3 awards · $1,710,277

   • 5U01DK127421-02Department: NIH department code

     Modulation and functional characterization of protein condensation in chromatin organization
     $1,086,587

     award amount
   • 5R01GM124334-04Department: NIH department code

     Structure mapping of molecular complexes by super-resolution microscopy
     $343,188

     award amount
   • 5R01GM131641-03Department: NIH department code

     Mapping endogenous protein dynamics in living cells
     $280,502

     award amount

7. Desai, Tejal A.

   Leads 2 awards · $1,277,469

   • 1T32GM139794-01Department: NIH department code

     UCSF/UCB Joint Graduate Group in Bioengineering
     $877,732

     award amount
   • 5R01HL137209-04Department: NIH department code

     Microstructural Cues for the Treatment of Heart Failure
     $399,737

     award amount

8. Shu, Xiaokun

   Leads 3 awards · $1,262,608

   • 5R35GM131766-03Department: NIH department code

     Designing a new class of fluorescent reporters for imaging dynamic cell signaling in live animals
     $582,692

     award amount
   • 1R01CA258327-01Department: NIH department code

     Imaging and manipulating oncoprotein phase separation and compartmentalization
     $429,916

     award amount
   • 3R35GM131766-03S1Department: NIH department code

     EQUIPMENT for Designing a new class of fluorescent reporters for imaging dynamic cell signaling in live animals
     $250,000

     award amount

9. Lim, Wendell A

   Leads 3 awards · $1,158,412

   • 1R01CA249018-01A1Department: NIH department code

     Recognizing the tumor ecosystem: Integrating stromal and cancer antigen signals to achieve precision recognition of solid tumors by CAR T cells
     $563,237

     award amount
   • 5R01CA220257-20Department: NIH department code

     Protein Recognition in Signal Transduction
     $345,206

     award amount
   • 3U54CA244438-01S3Department: NIH department code

     Engineering synthetic helper cells that autonomously deliver orthogonal IL-2 to selectively promote therapeutic T cell proliferation in tumors
     $249,969

     award amount

10. Hernandez, Ryan D.

    Leads 2 awards · $1,130,903

    • 5T32GM067547-19Department: NIH department code

      BMI Bioinformatics Training Grant
      $585,155

      award amount
    • 1R01GM142112-01Department: NIH department code

      Rarely Common: Uncovering the dominant role of rare variants in the genetic architecture of complex human traits.
      $545,748

      award amount

11. Kroetz, Deanna L

    Leads 2 awards · $1,119,168

    • 1R01CA261068-01Department: NIH department code

      Sphingolipid Signaling and Chemotherapy-Induced Peripheral Neurotoxicity
      $571,041

      award amount
    • 5T32GM007546-45Department: NIH department code

      Clinical Pharmacology, Drug Action and Pharmacogenetics
      $548,127

      award amount

12. Esquerra, Raymond M.

    Leads 1 award · $1,080,818

    • 5K12GM081266-15Department: NIH department code

      UCSF IRACDA Scholars Program
      $1,080,818

      award amount

13. Shoichet, Brian K

    Leads 1 award · $1,034,213

    • 5R35GM122481-05Department: NIH department code

      Development and Testing of New Computational Methods for Ligand Discovery and Mechanism
      $1,034,213

      award amount

14. Chen, Xin

    Leads 3 awards · $962,000

    • 1R01CA250227-01A1Department: NIH department code

      Investigating multifactorial beta-catenin activation in hepatocellular cancers
      $511,819

      award amount
    • 5R01CA239251-02Department: NIH department code

      Signaling pathways during hepatocarcinogenesis
      $369,431

      award amount
    • 5R03CA249236-02Department: NIH department code

      Cabozentinib based combination therapy for the treatment of hepatocellular carcinoma
      $80,750

      award amount

15. Ingraham, Holly A.

    Leads 2 awards · $954,132

    • 5R01DK121657-02Department: NIH department code

      Dissecting a hormone-responsive processor for female activity and repetitive behavior
      $485,776

      award amount
    • 5R01AG062331-03Department: NIH department code

      Arcuate ERa Signaling in Central Control of Female Bone Metabolism
      $468,356

      award amount

16. Phillips, Kathryn A

    Leads 1 award · $953,132

    • 1R01HG011792-01Department: NIH department code

      BUILDING THE EVIDENCE BASE FOR APPROPRIATE AND EFFICIENT IMPLEMENTATION OF EMERGING GENOMIC TESTS FOR DISEASE MANAGEMENT AND SCREENING
      $953,132

      award amount

17. Wells, James A

    Leads 2 awards · $898,220

    • 5R35GM122451-05Department: NIH department code

      Discovering how oncogenes remodel the surfaceome of cells
      $534,869

      award amount
    • 5R01CA248323-02Department: NIH department code

      New protein engineering-based tools and technologies for characterizing cell surface proteolysis in cancer cells for novel neo-epitope biomarkers and drug targets
      $363,351

      award amount

18. Kortemme, Tanja

    Leads 2 awards · $832,234

    • 5T32GM008284-34Department: NIH department code

      Molecular Biophysics Training Grant
      $483,372

      award amount
    • 5R01GM110089-06Department: NIH department code

      Computational design of new protein structures and interactions
      $348,862

      award amount

19. Roy, Shuvo

    Leads 1 award · $806,915

    • 3U01EB025136-03S1Department: NIH department code

      Implantable Bio-Artificial Pancreas (iBAP)
      $806,915

      award amount

20. Wang, Lei

    Leads 2 awards · $753,041

    • 1R01CA258300-01Department: NIH department code

      Covalent Protein Binders for Cancer Research and Therapy
      $402,207

      award amount
    • 5R01GM118384-06Department: NIH department code

      Adding new covalent bonds to proteins in live cells
      $350,834

      award amount

21. Alland, David

    Leads 1 award · $749,427

    • 5R01AI135124-03Department: NIH department code

      Identifying Optimal Treatment Strategies for Tuberculosis Treatment
      $749,427

      award amount

22. Irwin, John J.

    Leads 2 awards · $728,435

    • 5R01GM133836-03Department: NIH department code

      Ultra-large library docking for ligand discovery
      $389,285

      award amount
    • 2R01GM071896-16Department: NIH department code

      A Web-Based Automatic Virtual Screening System
      $339,150

      award amount

23. Degrado, William

    Leads 1 award · $711,887

    • 5R35GM122603-05Department: NIH department code

      Deciphering the relationship between structure, dynamics and function in helical bundle proteins
      $711,887

      award amount

24. Ferrin, Thomas E

    Leads 1 award · $646,003

    • 5R01GM129325-04Department: NIH department code

      ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling
      $646,003

      award amount

25. Arkin, Michelle

    Leads 2 awards · $644,986

    • 5R01GM130145-04Department: NIH department code

      Protein and small-molecule tools to probe the conformational dependence of the VCP/p97 protein-protein interaction network
      $340,709

      award amount
    • 1S10OD030265-01Department: NIH department code

      Bruker Sierra SPR-24 Pro
      $304,277

      award amount

26. Duncan, D'anne S.

    Leads 1 award · $625,555

    • 5R25GM056847-23Department: NIH department code

      Maximizing Opportunities for Research Excellence
      $625,555

      award amount

27. Abate, Adam R.

    Leads 1 award · $621,029

    • 5R01EB019453-07Department: NIH department code

      Gigapixel digital PCR in Giant Unilamellar Vesicles
      $621,029

      award amount

28. Florez, Jose Carlos

    Leads 1 award · $599,475

    • 5R01GM117163-06Department: NIH department code

      Discovery of Pharmacogenomic Biomarkers for OATP1B1 and OATP1B3
      $599,475

      award amount

29. El-Samad, Hana

    Leads 1 award · $584,698

    • 1U01CA265697-01Department: NIH department code

      Synthetic circuits that drive infiltration of therapeutic T cells into immunologically cold tumors
      $584,698

      award amount

30. Nicoll, Roger A

    Leads 1 award · $584,458

    • 5R01MH117139-04Department: NIH department code

      The synaptic cleft and glutamate receptor trafficking
      $584,458

      award amount

31. Arkin, Michelle

    Leads 1 award · $577,690

    • 5R01CA250459-02Department: NIH department code

      Discovery of Small Molecule Ligands for PHD1 Reader Domain of Histone Demethylase KDM5A
      $577,690

      award amount

32. Craik, Charles Scott

    Leads 1 award · $544,331

    • 5T32GM064337-20Department: NIH department code

      Research Training in Chemistry and Chemical Biology
      $544,331

      award amount

33. Renslo, Adam R

    Leads 1 award · $536,653

    • 5R01AI105106-09Department: NIH department code

      Chemical Methods for Ferrous Iron Dependent Drug Delivery
      $536,653

      award amount

34. Bandyopadhyay, Sourav

    Leads 1 award · $503,415

    • 5R01CA238236-02Department: NIH department code

      Stress responses drive resistance and shape tumor evolution in EGFR mutant lung cancer
      $503,415

      award amount

35. Mullins, R Dyche

    Leads 1 award · $484,500

    • 2R35GM118119-06Department: NIH department code

      Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells
      $484,500

      award amount

36. Fraser, James Solomon

    Leads 1 award · $467,162

    • 5R01GM123159-04Department: NIH department code

      Resolving ensemble averaged conformations by multi-temperature x-ray crystallography
      $467,162

      award amount

37. Sello, Jason K

    Leads 1 award · $457,161

    • 5R01AI123400-06Department: NIH department code

      Studies of the antibacterial activity of and resistance to molecules targeting the ClpP peptidase
      $457,161

      award amount

38. Ahituv, Nadav

    Leads 1 award · $453,005

    • 5T32GM007175-45Department: NIH department code

      Pharmaceutical Sciences and Pharmacogenomics
      $453,005

      award amount

39. Correia, Maria Almira

    Leads 1 award · $452,200

    • 5R01GM044037-27Department: NIH department code

      Hepatic degradation of cytochrome P450 enzymes
      $452,200

      award amount

40. Fujimori, Danica Galonic

    Leads 1 award · $440,566

    • 5R01AI137270-04Department: NIH department code

      Radical SAM-dependent methylation in antibiotic resistance
      $440,566

      award amount

41. Barbosa De Almeida, Ricardo Augusto

    Leads 1 award · $413,916

    • 1R01CA253017-01A1Department: NIH department code

      Synthetic epigenetic circuits: tunable cell fate switches controlled by dynamic and combinatorial inputs
      $413,916

      award amount

42. Collisson, Eric

    Leads 1 award · $410,565

    • 5R01CA230263-03Department: NIH department code

      The structural and functional basis of MET exon 14 activation and acquired drug resistance
      $410,565

      award amount

43. Giacomini, Kathleen M

    Leads 1 award · $407,602

    • 1R01GM139875-01Department: NIH department code

      Characterizing the physiological and pharmacological roles of SLC22A24
      $407,602

      award amount

44. Douglas, Shawn M

    Leads 1 award · $403,750

    • 5R35GM125027-04Department: NIH department code

      DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules
      $403,750

      award amount

45. Jura, Natalia

    Leads 1 award · $403,750

    • 1R35GM139636-01Department: NIH department code

      Structural and Functional Studies of HER Receptors
      $403,750

      award amount

46. Shokat, Kevan M.

    Leads 1 award · $403,712

    • 5R01CA244550-02Department: NIH department code

      Inhibitors of the G protein GNAS which drives pancreatic tumorigenesis
      $403,712

      award amount

47. England, Pamela Michael

    Leads 1 award · $353,281

    • 5R01NS108404-04Department: NIH department code

      Selective modulators for the nuclear receptor Nurr1
      $353,281

      award amount

48. Sali, Andrej

    Leads 1 award · $342,380

    • 2R01GM083960-13A1Department: NIH department code

      IMP: Software for Hybrid Determination of Macromolecular Assembly Structures
      $342,380

      award amount

49. Swaney, Danielle L

    Leads 1 award · $329,976

    • 5R01GM133981-03Department: NIH department code

      A universal multiplexing approach to unlock the hidden proteome
      $329,976

      award amount

50. Huang, Liusheng

    Leads 1 award · $242,250

    • 1R21AI153848-01A1Department: NIH department code

      Unbound piperaquine pharmacokinetic exposure in Ugandan pregnant women and children receiving malaria chemoprevention
      $242,250

      award amount

51. Deitchman, Amelia N

    Leads 1 award · $201,150

    • 1K23AI162249-01Department: NIH department code

      Clinical Pharmacology Approaches towards Accelerating HIV Cure Initiatives
      $201,150

      award amount

52. Oni-Orisan, Akinyemi

    Leads 1 award · $177,498

    • 5K01HL143109-04Department: NIH department code

      Characterization of response to lipid-modifying regimens for atherosclerotic cardiovascular disease using electronic health records
      $177,498

      award amount

53. Krogan, Nevan J

    Leads 1 award · $175,631

    • 5R21CA235303-03Department: NIH department code

      CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer
      $175,631

      award amount

54. Mann, Samuel I

    Leads 2 awards · $148,352

    • 1K99GM143529-01Department: NIH department code

      De novo design of functional metallocofactor-binding proteins
      $93,968

      award amount
    • 5F32GM130029-03Department: NIH department code

      De Novo Design of Functional Metalloporphyrin-Containing Proteins
      $54,384

      award amount

55. Herber, Candice

    Leads 1 award · $130,424

    • 5K01AG065916-02Department: NIH department code

      Unraveling Mechanisms Driving Female-Specific Osteogenesis after Disrupting a Brain-to-Bone Circuit
      $130,424

      award amount

56. Newberry, Robert William

    Leads 1 award · $99,943

    • 1K99NS116679-01A1Department: NIH department code

      Biophysical Determinants of Physiological and Pathological alpha-Synuclein Membrane Interactions
      $99,943

      award amount

57. Polizzi, Nicholas

    Leads 1 award · $99,360

    • 5K99GM135519-02Department: NIH department code

      De novo design of small-molecule-binding proteins
      $99,360

      award amount

58. Glasgow, Anum Azam

    Leads 1 award · $97,199

    • 5K99GM135529-02Department: NIH department code

      Mapping and rewiring protein allostery
      $97,199

      award amount

59. Kratochvil, Huong Tran

    Leads 1 award · $97,159

    • 5K99GM138753-02Department: NIH department code

      Proton Conduction Pathways in Proton Channel Proteins
      $97,159

      award amount

60. Zhou, Xin

    Leads 1 award · $86,940

    • 5K99EB030587-02Department: NIH department code

      Interrogating and rewiring cell signaling pathways in CAR-T cells with synthetic phosphotyrosine recognition domains
      $86,940

      award amount

61. Morstein, Johannes

    Leads 1 award · $83,268

    • 4K00CA253758-02Department: NIH department code

      Lipid-based Cancer Therapeutics
      $83,268

      award amount

62. Peacock, David Matthew

    Leads 1 award · $68,562

    • 5F32CA253966-02Department: NIH department code

      Targeting the GTP-bound state of oncogenic Ras proteins
      $68,562

      award amount

63. Zhou, Jie

    Leads 1 award · $68,562

    • 5F32CA236151-03Department: NIH department code

      Unveiling the Oncogenic Roles of ADAM10/17 by Comprehensively Profiling Proteolytic Activity on a Synthetic Human Protein Peptide Phage Library
      $68,562

      award amount

64. Bender, Brian J

    Leads 1 award · $66,390

    • 5F32GM136062-02Department: NIH department code

      Advancing Homology Models to Identify Compounds for Understudied GPCRs
      $66,390

      award amount

65. Bouhaddou, Mehdi

    Leads 1 award · $66,390

    • 5F32CA239333-03Department: NIH department code

      Systematic Targeting of Oncogene Interacting Proteins to Reveal New Therapeutic Strategies
      $66,390

      award amount

66. Byrnes, James Robert

    Leads 1 award · $65,994

    • 5F32CA239417-03Department: NIH department code

      Characterizing and Targeting the Hypoxic T Cell Surfaceome to Promote Immune Function in Cancer
      $65,994

      award amount

67. Chalkley, Matthew

    Leads 1 award · $65,994

    • 5F32GM139379-02Department: NIH department code

      O2-Reactivity in De Novo Designed Mononuclear, Non-Heme Fe Proteins
      $65,994

      award amount

68. Huycke, Tyler

    Leads 1 award · $65,994

    • 1F32DK128949-01Department: NIH department code

      Mechanochemical mechanisms of intestinal villus development and regeneration
      $65,994

      award amount

69. Jiang, Ziwen

    Leads 1 award · $65,994

    • 1F32GM139242-01A1Department: NIH department code

      Understanding the effects of p97 protein-protein interactions on cellular functions using antibody-based inhibitors
      $65,994

      award amount

70. Schneider, Samuel H.

    Leads 1 award · $65,994

    • 1F32GM142183-01Department: NIH department code

      Development of a Mechanism and Structure-Guided Methodology for De Novo Enzyme Design
      $65,994

      award amount

71. Lou, Kevin

    Leads 1 award · $51,036

    • 5F30CA239476-03Department: NIH department code

      Investigating functional interactions with KRAS G12C inhibition
      $51,036

      award amount

72. Aweeka, Francesca T.

    Leads 1 award · $47,014

    • 3R01HD068174-10S1Department: NIH department code

      Optimizing ACT use for African children in the setting of HIV and malnutrition
      $47,014

      award amount

73. Harshman, Lana

    Leads 1 award · $46,036

    • 5F31HG011568-02Department: NIH department code

      Determining the influence of 3D chromatin structure on human evolution
      $46,036

      award amount

74. Chong, Megan Kaiulani

    Leads 1 award · $41,421

    • 1F31CA265136-01Department: NIH department code

      Error Correction in Mammalian Mitosis: Defining Physical Cues and Integration Mechanisms
      $41,421

      award amount

75. Young, Iris Diane

    Leads 1 award · $41,099

    • 5F32GM133129-03Department: NIH department code

      Disentangling conformational and compositional heterogeneity
      $41,099

      award amount

76. Kirkemo, Lisa

    Leads 1 award · $41,081

    • 5F31CA247527-02Department: NIH department code

      Mechanistic Insights and Diagnostic Applications for Hypoxia-Induced Vasorin in Pancreatic Cancer
      $41,081

      award amount

77. Zhu, Lawrence Yang

    Leads 1 award · $37,830

    • 1F31NS122434-01Department: NIH department code

      Probing the Role of the LRRK2 GTPase in Parkinson's Disease
      $37,830

      award amount

78. Wassarman, Douglas Ryan

    Leads 1 award · $37,796

    • 5F31CA243439-03Department: NIH department code

      A Chemical-Genetic Platform for Interrogating Specific mTOR Functions
      $37,796

      award amount

79. McGinnis, Christopher

    Leads 1 award · $25,955

    • 1F31CA257349-01Department: NIH department code

      Interrogating Immunomodulation for Anti-Metastatic Therapy
      $25,955

      award amount

80. Pance, Katarina

    Leads 1 award · $18,506

    • 1F31CA265080-01Department: NIH department code

      Development of novel targeted degradation strategies to modulate immunosuppressive adenosine signaling in cancer
      $18,506

      award amount

81. Lee, David John

    Leads 1 award · $5,925

    • 5F32AI148120-03Department: NIH department code

      CryoEM guided enhancement of ribosome-targeting antibiotics
      $5,925

      award amount

82. Wu, Lani F

    Leads 1 award · $1

    • 5R01CA184984-07Department: NIH department code

      Maximizing the predictive power of high-throughput, microscopy-based phenotypic screens
      $1

      award amount