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FY2025 NIH awards · Principal investigators

Pharmacology at University of California, San Francisco

San Francisco, CA

Funding
$42.1M
$42,058,614
Awards
80
FY2025 NIH awards in Pharmacology
Principal investigators
71
55 lead a grant here, 16 co-investigators
Department rank
#1
of 127 · Ranking
  • NIH names only the principal investigators on an award, so this page lists only them. The department is the award's: it is where ScienceDex counts the award, not a list of the department's members.
  • These are the awards in the Pharmacology row of the University of California, San Francisco page.

Leads a grant in this department

55 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

  1. Radojka Savic

    Leads 3 awards · $8,449,857

    • 5UM1AI179699-02Department: NIH department code
      Preclinical Design and Clinical Translation of TB Regimens (PReDicTR) Consortium

      Principal investigators: Radojka Savic (contact PI), Dirk Schnappinger, Eric L Nuermberger, Kelly E. Dooley

      $7,200,000
      award amount
    • 1R01AI192977-01Department: NIH department code
      Diagnosis of tuberculosis and monitoring of treatment via RNA liquid biopsy

      Principal investigators: Radojka Savic (contact PI), Adithya Cattamanchi, Iwijn De Vlaminck

      $743,651
      award amount
    • 2T32GM007546-49Department: NIH department code
      Clinical Pharmacology, Drug Action and Pharmacogenetics
      $506,206
      award amount

  2. Wendell A Lim

    Leads 5 awards · $2,850,640

    • 5R01DK132547-04Department: NIH department code
      Engineering synthetic immune cells with modular sentinel and therapeutic functions for T1D
      $833,374
      award amount
    • 5U01CA265697-05Department: NIH department code
      Synthetic circuits that drive infiltration of therapeutic T cells into immunologically cold tumors

      Principal investigators: Wendell A Lim (contact PI), Hana El-Samad

      $584,012
      award amount
    • 5R01CA249018-05Department: NIH department code
      Recognizing the tumor ecosystem: Integrating stromal and cancer antigen signals to achieve precision recognition of solid tumors by CAR T cells
      $563,237
      award amount
    • 5R01CA258789-04Department: NIH department code
      Ameliorating off-target toxicities of CAR T cells by engineering NOT gates
      $453,550
      award amount
    • 5R01CA253017-05Department: NIH department code
      Synthetic epigenetic circuits: tunable cell fate switches controlled by dynamic and combinatorial inputs

      Principal investigators: Wendell A Lim (contact PI), Ricardo Augusto Barbosa De Almeida

      $416,467
      award amount

  3. Holly A. Ingraham

    Leads 3 awards · $2,689,859

    • 5K12GM081266-18Department: NIH department code
      The UCSF IRACDA Scholars Program.

      Principal investigators: Holly A. Ingraham (contact PI), Raymond M. Esquerra

      $1,331,411
      award amount
    • 5R01DK135714-03Department: NIH department code
      Understanding Mechanisms and Sex-Differences in Visceral Pain

      Principal investigators: Holly A. Ingraham (contact PI), David Julius

      $852,896
      award amount
    • 5U01AG086165-02Department: NIH department code
      Rejuvenating Skeletal Health Through A Novel Brain-Bone Axis
      $505,552
      award amount

  4. Ryan D. Hernandez

    Leads 3 awards · $2,125,747

    • 1R01HL175076-01A1Department: NIH department code
      Genetic ancestry effects on molecular and complex traits in TOPMed

      Principal investigators: Ryan D. Hernandez (contact PI), Dara Torgerson

      $804,982
      award amount
    • 5T32GM150479-02Department: NIH department code
      BMI Bioinformatics Training Grant
      $703,979
      award amount
    • 1R35GM158240-01Department: NIH department code
      Human evolution and the genetic architecture of complex traits
      $616,786
      award amount

  5. Adam R. Abate

    Leads 3 awards · $1,801,802

    • 5R01AI176829-03Department: NIH department code
      Next Generation Infectious Disease Diagnostics: Microfluidic-Free Gigapixel PCR with Self-Assembled Partitioning
      $617,550
      award amount
    • 5R01AI178795-10Department: NIH department code
      Gigapixel Next-Generation-Sequencing: An Ultra-Sensitive Diagnostic for Infections of the CNS
      $610,589
      award amount
    • 5R01NS130876-03Department: NIH department code
      Identification of Regulatory Mechanisms Operating in Rare Pathogenic Astrocyte Subsets in Multiple Sclerosis with a Novel Genomic Technology

      Principal investigators: Adam R. Abate (contact PI), Carlo L Condello, Jonah R Chan

      $573,663
      award amount

  6. Tanja Kortemme

    Leads 2 awards · $1,787,021

    • 1DP1EB038939-01Department: NIH department code
      De novo design and engineering of biological error correction
      $1,148,000
      award amount
    • 5R35GM145236-04Department: NIH department code
      Computational design of proteins and protein functions
      $639,021
      award amount

  7. Su Guo

    Leads 4 awards · $1,730,052

    • 5T32GM142516-04Department: NIH department code
      Pharmaceutical Sciences and Pharmacogenomics
      $490,150
      award amount
    • 5R01DA053385-04Department: NIH department code
      Role of endocannabinoid signaling in a preference/aversion circuitry
      $444,072
      award amount
    • 5R01NS120219-05Department: NIH department code
      Mechanisms of renin-angiotensin signaling in programmed and insult-induced neuronal death
      $403,750
      award amount
    • 5R01NS120218-05Department: NIH department code
      Asymmetric Cell Division of Vertebrate Radial Glia Neural Progenitors
      $392,080
      award amount

  8. Kathleen M Giacomini

    Leads 2 awards · $1,393,661

    • 5UC2HD113474-03Department: NIH department code
      Transporter Elucidation Center at the University of California, San Francisco

      Principal investigators: Kathleen M Giacomini (contact PI), Robert M Stroud

      $968,661
      award amount
    • 5U01FD005978-10Department: NIH department code
      UCSF-Stanford Center of Excellence in Regulatory Science and Innovation

      Principal investigators: Kathleen M Giacomini (contact PI), Russ Biagio Altman

      $425,000
      award amount

  9. Aashish Manglik

    Leads 3 awards · $1,375,554

    • 5R01DC021585-02Department: NIH department code
      Structural dynamics of human odorant receptors in olfaction

      Principal investigators: Aashish Manglik (contact PI), Hiroaki Matsunami, Nagarajan Vaidehi

      $648,575
      award amount
    • 5T32GM149436-03Department: NIH department code
      Molecular Biophysics Training Grant
      $408,272
      award amount
    • 5R01GM138992-04Department: NIH department code
      Mechanisms of Smoothened Activation in Hedgehog Signaling
      $318,707
      award amount

  10. Zev Jordan Gartner

    Leads 2 awards · $1,070,089

    • 2R01DK126376-06Department: NIH department code
      A molecular and physical mechanism for growing and branching the intestinal villus
      $678,386
      award amount
    • 1R33CA297969-01Department: NIH department code
      Increasing organoid reproducibility and complexity for drug testing and disease modeling
      $391,703
      award amount

  11. Nadav Ahituv

    Leads 2 awards · $1,026,433

    • 5R01CA283826-02Department: NIH department code
      Bioengineering adipocytes for cancer therapy
      $643,369
      award amount
    • 5R01HG012396-04Department: NIH department code
      EDGE CMT: Genomic characterization of mammalian adaptation to frugivory
      $383,064
      award amount

  12. Xiaokun Shu

    Leads 2 awards · $1,021,628

    • 5R35GM131766-07Department: NIH department code
      Designing a new class of fluorescent reporters for imaging dynamic cell signaling in live animals
      $591,712
      award amount
    • 5R01CA258327-05Department: NIH department code
      Imaging and manipulating oncoprotein phase separation and compartmentalization
      $429,916
      award amount

  13. James A Wells

    Leads 2 awards · $976,420

    • 5R35GM122451-08Department: NIH department code
      Surfaceomic technologies and antibodies to probe cell surface proteomes and their interactomes at unprecedented small scale and high-resolution
      $572,243
      award amount
    • 2R01CA248323-06Department: NIH department code
      New protein-engineered tools and technologies for identifying, deorphanizing, and targeting shed proteins in cancer
      $404,177
      award amount

  14. Kathryn A Phillips

    Leads 1 award · $852,472

    • 5R01HG011792-05Department: NIH department code
      BUILDING THE EVIDENCE BASE FOR APPROPRIATE AND EFFICIENT IMPLEMENTATION OF EMERGING GENOMIC TESTS FOR DISEASE MANAGEMENT AND SCREENING
      $852,472
      award amount

  15. Brian K Shoichet

    Leads 1 award · $798,338

    • 5R35GM122481-09Department: NIH department code
      Development and Testing of New Computational Methods for Ligand Discovery and Mechanism
      $798,338
      award amount

  16. Dorothy Elinor Apollonio

    Leads 1 award · $680,802

    • 5R01DA058687-02Department: NIH department code
      Using opioid industry documents to understand marketing of addictive medications
      $680,802
      award amount

  17. Steven J Altschuler

    Leads 1 award · $680,507

    • 1R01CA300245-01Department: NIH department code
      Elucidate the landscape of druggable targets for eliminating cancer persister cells
      $680,507
      award amount

  18. William Degrado

    Leads 1 award · $666,046

    • 5R35GM122603-09Department: NIH department code
      Deciphering the relationship between structure, dynamics and function in helical bundle proteins
      $666,046
      award amount

  19. Thomas E Ferrin

    Leads 1 award · $664,692

    • 5R01GM129325-08Department: NIH department code
      ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling
      $664,692
      award amount

  20. Jason E Gestwicki

    Leads 1 award · $639,540

    • 5T32GM145460-04Department: NIH department code
      Research Training in Chemistry and Chemical Biology
      $639,540
      award amount

  21. James Solomon Fraser

    Leads 1 award · $597,550

    • 5R35GM145238-04Department: NIH department code
      Discovering and Manipulating Macromolecular Conformational Ensembles
      $597,550
      award amount

  22. Hyunil Jo

    Leads 1 award · $576,728

    • 5R01DK137892-02Department: NIH department code
      Targeting Acid Ceramidase for Hepatic Fibrogenesis
      $576,728
      award amount

  23. Akinyemi Oni-Orisan

    Leads 2 awards · $559,265

    • 5R01HG012824-03Department: NIH department code
      Genetic and social determinants of pharmacological health outcomes in ancestrally diverse populations
      $526,615
      award amount
    • 3R01HG012824-03S1Department: NIH department code
      Genetic and social determinants of pharmacological health outcomes in ancestrally diverse populations
      $32,650
      award amount

  24. Danica Galonic Fujimori

    Leads 1 award · $516,158

    • 5R01AI137270-07Department: NIH department code
      Radical SAM-dependent methylation in antibiotic resistance
      $516,158
      award amount

  25. Matthew N McCarroll

    Leads 1 award · $484,500

    • 5DP1DA058350-03Department: NIH department code
      New Technologies for Accelerating the Discovery and Characterization of Neuroactives that Address Substance Use Disorders
      $484,500
      award amount

  26. R Dyche Mullins

    Leads 1 award · $484,500

    • 5R35GM118119-10Department: NIH department code
      Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells
      $484,500
      award amount

  27. Lani F Wu

    Leads 1 award · $454,630

    • 5R01CA184984-11Department: NIH department code
      Maximizing the predictive power of high-throughput, microscopy-based phenotypic screens
      $454,630
      award amount

  28. Kliment A Verba

    Leads 1 award · $412,077

    • 5R01GM144694-04Department: NIH department code
      Atomic-level probing of the peptidoglycan biosynthetic machinery in bacterial cell wall biogenesis
      $412,077
      award amount

  29. Lei Wang

    Leads 1 award · $404,218

    • 5R01CA258300-05Department: NIH department code
      Covalent Protein Binders for Cancer Research and Therapy
      $404,218
      award amount

  30. Katherine Julia Susa

    Leads 1 award · $403,750

    • 5DP5OD036136-03Department: NIH department code
      Identifying, Characterizing, and Targeting Regulators of B Cell Activation
      $403,750
      award amount

  31. Shawn M Douglas

    Leads 1 award · $403,750

    • 5R35GM125027-08Department: NIH department code
      DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules
      $403,750
      award amount

  32. Amelia N Deitchman

    Leads 2 awards · $357,101

    • 5R21AI184166-02Department: NIH department code
      Characterizing Antiviral Washout and Viral Rebound during Analytic Treatment Interruption Studies
      $205,000
      award amount
    • 5K23AI162249-05Department: NIH department code
      Clinical Pharmacology Approaches towards Accelerating HIV Cure Initiatives
      $152,101
      award amount

  33. Nicole Delrosso

    Leads 1 award · $350,461

    • 1DP5OD039380-01Department: NIH department code
      Novel high-throughput approaches to discover and dissect human transcriptional protein interactions
      $350,461
      award amount

  34. Bo Huang

    Leads 1 award · $347,225

    • 5R01GM131641-07Department: NIH department code
      Mapping endogenous protein dynamics in living cells
      $347,225
      award amount

  35. John D Gross

    Leads 1 award · $318,234

    • 5R01GM148881-03Department: NIH department code
      Molecular Mechanisms that Control mRNA Decapping in Biological Condensates
      $318,234
      award amount

  36. Michelle Arkin

    Leads 1 award · $316,655

    • 5R01GM147696-04Department: NIH department code
      Systematic stabilization of specific protein-protein interactions
      $316,655
      award amount

  37. Bani Tamraz

    Leads 1 award · $206,050

    • 5R21AI177219-02Department: NIH department code
      Quantifying genomic and pharmacometabolomic differences in antiretroviral exposure in MACS/WIHS Combined Cohort Study
      $206,050
      award amount

  38. Emily A Hammad Mrig

    Leads 1 award · $205,418

    • 5K01HG013687-02Department: NIH department code
      Promoting Access to Payment Pathways for Emerging Molecular Diagnostics
      $205,418
      award amount

  39. Liusheng Huang

    Leads 1 award · $205,000

    • 5R21AI185534-02Department: NIH department code
      Precise field-friendly methods for quantification of antimalarial drugs in dried blood spots
      $205,000
      award amount

  40. Chengyu Deng

    Leads 1 award · $135,206

    • 1K99HG014204-01Department: NIH department code
      Developing Single-Cell Functional Genomic Technologies to Investigate DNA Methylation Changes in Human Diseases
      $135,206
      award amount

  41. Lee Schnaider

    Leads 1 award · $124,767

    • 1K99GM157551-01Department: NIH department code
      Probing the Rules of Protein Structure-Function Relationships through the De Novo Design of Functional Proteins
      $124,767
      award amount

  42. Austin Joseph Graham

    Leads 1 award · $124,738

    • 1K99EB037059-01Department: NIH department code
      Dynamically reconfigurable materials for 4D bioprinting of a human gut-brain axis
      $124,738
      award amount

  43. Anna Katherine Hatstat

    Leads 1 award · $118,904

    • 5K99GM155611-02Department: NIH department code
      Revealing signal transduction mechanisms through protein design
      $118,904
      award amount

  44. Noah Greenwald

    Leads 1 award · $94,091

    • 4K00CA264307-03Department: NIH department code
      USING DEEP MUTATIONAL SCANNING TO CHARACTERIZE TUMOR-IMMUNE INTERACTIONS
      $94,091
      award amount

  45. Ian Bakanas

    Leads 1 award · $75,520

    • 5F32GM154484-02Department: NIH department code
      De novo design of photoacid-binding proteins to study proton dynamics in biological systems
      $75,520
      award amount

  46. Olivier Mailhot

    Leads 1 award · $75,520

    • 5F32GM154469-02Department: NIH department code
      Rational prioritization algorithm for docking-based virtual screening of trillion-scale make-on-demand small molecule libraries
      $75,520
      award amount

  47. Trenton Peters-Clarke

    Leads 1 award · $75,520

    • 1F32CA298768-01A1Department: NIH department code
      Toward Understanding the Functional Landscape of Proteolysis at the Cell Surface
      $75,520
      award amount

  48. Ryder Easterlin

    Leads 1 award · $47,497

    • 5F31HG013464-02Department: NIH department code
      The cis-regulatory basis of lineage-specific phenotypes among human groups
      $47,497
      award amount

  49. Jordan Isabelle Kleinman

    Leads 1 award · $47,120

    • 5F31AI181568-02Department: NIH department code
      Elucidating the role of context-specificity in oxazolidinone mechanism of action
      $47,120
      award amount

  50. Nathan Cho

    Leads 1 award · $45,456

    • 5F31CA275394-02Department: NIH department code
      Defining the mechanisms by which NuMA drives spindle mechanical robustness
      $45,456
      award amount

  51. Carolyn Ku

    Leads 1 award · $42,525

    • 1F31HL178181-01Department: NIH department code
      Advancing understanding of cardiac regeneration through comparative analysis across vertebrates
      $42,525
      award amount

  52. Victoria Bowcut

    Leads 1 award · $42,277

    • 1F31CA301949-01Department: NIH department code
      The Development of Selective Inhibitors to Oncogenic Rac1 Variants
      $42,277
      award amount

  53. Zachary Mullin-Bernstein

    Leads 1 award · $42,057

    • 5F31CA291047-02Department: NIH department code
      Defining the Mechanistic Impact of PRC1 Overexpression on Mammalian Spindle Mechanics
      $42,057
      award amount

  54. Lee Rao

    Leads 1 award · $41,493

    • 5F31CA288086-02Department: NIH department code
      Accurate interaction detection in combinatorial screens with complex phenotypes
      $41,493
      award amount

  55. Vanna Tran

    Leads 1 award · $41,493

    • 1F31GM156031-01A1Department: NIH department code
      Defining the mechanisms underlying the mammalian kinetochore's structural integrity under force
      $41,493
      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.