Pharmacology at University of California, San Francisco

Leads a grant in this department

70 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Krogan, Nevan J

   Leads 2 awards · $67,481,608

   • 1U19AI171110-01Department: NIH department code

     QCRG Pandemic Response Program
     $67,452,049

     award amount
   • 1R13AI154985-01A1Department: NIH department code

     International West Africa Symposium and Workshop on Infectious Diseases
     $29,559

     award amount

2. Altman, Russ Biagio

   Leads 7 awards · $6,645,383

   • 5U01FD005978-07Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $4,985,961

     award amount
   • 3U01FD005978-06S4Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $580,000

     award amount
   • 3U01FD005978-06S2Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $435,336

     award amount
   • 3U01FD005978-07S2Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $245,113

     award amount
   • 3U01FD005978-06S3Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $200,000

     award amount
   • 3U01FD005978-06S1Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $155,626

     award amount
   • 3U01FD005978-07S1Department: NIH department code

     UCSF-Stanford Center of Excellence in Regulatory Science and Innovation
     $43,347

     award amount

3. Lim, Wendell A

   Leads 6 awards · $1,885,847

   • 1R01DK132547-01Department: NIH department code

     Engineering synthetic immune cells with modular sentinel and therapeutic functions for T1D
     $830,753

     award amount
   • 1R01CA258789-01A1Department: NIH department code

     Ameliorating off-target toxicities of CAR T cells by engineering NOT gates
     $451,135

     award amount
   • 5R01CA220257-21Department: NIH department code

     Protein Recognition in Signal Transduction
     $338,302

     award amount
   • 5R01CA249018-02Department: NIH department code

     Recognizing the tumor ecosystem: Integrating stromal and cancer antigen signals to achieve precision recognition of solid tumors by CAR T cells
     $147,001

     award amount
   • 3U54CA244438-01S4Department: NIH department code

     UCSF Center for Synthetic Immunology: Tools to Reprogram the Immune System to Combat Cancer
     $59,328

     award amount
   • 3U54CA244438-01S5Department: NIH department code

     UCSF Center for Synthetic Immunology: Tools to Reprogram the Immune System to Combat Cancer
     $59,328

     award amount

4. Gartner, Zev Jordan

   Leads 4 awards · $1,845,334

   • 5R01DK126376-03Department: NIH department code

     The physical and molecular mechanisms of intestinal villus morphogenesis and repair
     $569,551

     award amount
   • 5U01CA244109-03Department: NIH department code

     Understanding breast cancer progression as a defect in the mechanics of tissue self-organization
     $566,166

     award amount
   • 5R33CA247744-02Department: NIH department code

     Universal Sample Multiplexing for Single Cell Analysis
     $390,654

     award amount
   • 5R01GM135462-04Department: NIH department code

     MULTIseq: multiplexing massively parallel single cell transcriptional analysis across time, space, and conditions
     $318,963

     award amount

5. Guo, Su

   Leads 6 awards · $1,805,138

   • 1R01DA053385-01A1Department: NIH department code

     Role of endocannabinoid signaling in a preference/aversion circuitry
     $444,072

     award amount
   • 5R01GM132500-04Department: NIH department code

     Mechanisms that drive the variation of aversive behavior
     $430,236

     award amount
   • 5R01NS120219-02Department: NIH department code

     Mechanisms of renin-angiotensin signaling in programmed and insult-induced neuronal death
     $403,750

     award amount
   • 5R01NS120218-02Department: NIH department code

     Asymmetric Cell Division of Vertebrate Radial Glia Neural Progenitors
     $392,080

     award amount
   • 3R01DA053385-01A1S1Department: NIH department code

     Diversity Supplement
     $95,826

     award amount
   • 3R01NS120218-01A1S1Department: NIH department code

     Diversity Supplement
     $39,174

     award amount

6. Ahituv, Nadav

   Leads 3 awards · $1,512,437

   • 5R01MH116438-05Department: NIH department code

     Massively parallel characterization of psychiatric disease associated regulatory elements in defined cell types
     $667,990

     award amount
   • 1T32GM142516-01Department: NIH department code

     Pharmaceutical Sciences and Pharmacogenomics
     $476,062

     award amount
   • 1R01HG012396-01Department: NIH department code

     EDGE CMT: Genomic characterization of mammalian adaptation to frugivory
     $368,385

     award amount

7. Huang, Bo

   Leads 2 awards · $1,367,089

   • 5U01DK127421-03Department: NIH department code

     Modulation and functional characterization of protein condensation in chromatin organization
     $1,086,587

     award amount
   • 5R01GM131641-04Department: NIH department code

     Mapping endogenous protein dynamics in living cells
     $280,502

     award amount

8. Kroetz, Deanna L

   Leads 3 awards · $1,251,751

   • 5T32GM007546-46Department: NIH department code

     Clinical Pharmacology, Drug Action and Pharmacogenetics
     $626,867

     award amount
   • 5R01CA261068-02Department: NIH department code

     Sphingolipid Signaling and Chemotherapy-Induced Peripheral Neurotoxicity
     $562,905

     award amount
   • 3R01CA261068-02S1Department: NIH department code

     Contribution of Nuclear S1P Signaling to Microtubule Targeting Agent-Induced Changes in Transcriptional Activity in Human iPS-SNs
     $61,979

     award amount

9. Kortemme, Tanja

   Leads 3 awards · $1,204,448

   • 5T32GM008284-35Department: NIH department code

     Molecular Biophysics Training Grant
     $519,378

     award amount
   • 5R01GM110089-07Department: NIH department code

     Computational design of new protein structures and interactions
     $348,862

     award amount
   • 1R35GM145236-01Department: NIH department code

     Computational design of proteins and protein functions
     $336,208

     award amount

10. Hernandez, Ryan D.

    Leads 2 awards · $1,170,182

    • 5T32GM067547-20Department: NIH department code

      BMI Bioinformatics Training Grant
      $624,434

      award amount
    • 5R01GM142112-02Department: NIH department code

      Rarely Common: Uncovering the dominant role of rare variants in the genetic architecture of complex human traits.
      $545,748

      award amount

11. Ingraham, Holly A.

    Leads 3 awards · $1,121,766

    • 5R01DK121657-03Department: NIH department code

      Dissecting a hormone-responsive processor for female activity and repetitive behavior
      $484,355

      award amount
    • 5R01AG062331-04Department: NIH department code

      Arcuate ERa Signaling in Central Control of Female Bone Metabolism
      $468,356

      award amount
    • 3R01DK121657-03S1Department: NIH department code

      Dissecting a hormone-responsive processor for female activity and repetitive behavior
      $169,055

      award amount

12. Esquerra, Raymond M.

    Leads 1 award · $1,080,819

    • 3K12GM081266-15S1Department: NIH department code

      UCSF IRACDA Scholars Program
      $1,080,819

      award amount

13. Shu, Xiaokun

    Leads 2 awards · $1,004,006

    • 5R35GM131766-04Department: NIH department code

      Designing a new class of fluorescent reporters for imaging dynamic cell signaling in live animals
      $582,692

      award amount
    • 5R01CA258327-02Department: NIH department code

      Imaging and manipulating oncoprotein phase separation and compartmentalization
      $421,314

      award amount

14. Phillips, Kathryn A

    Leads 1 award · $937,434

    • 5R01HG011792-02Department: NIH department code

      BUILDING THE EVIDENCE BASE FOR APPROPRIATE AND EFFICIENT IMPLEMENTATION OF EMERGING GENOMIC TESTS FOR DISEASE MANAGEMENT AND SCREENING
      $937,434

      award amount

15. Hernandez, Christopher John

    Leads 1 award · $936,651

    • 5T32GM139794-02Department: NIH department code

      UCSF/UCB Joint Graduate Group in Bioengineering
      $936,651

      award amount

16. Shoichet, Brian K

    Leads 1 award · $798,338

    • 2R35GM122481-06Department: NIH department code

      Development and Testing of New Computational Methods for Ligand Discovery and Mechanism
      $798,338

      award amount

17. Oni-Orisan, Akinyemi

    Leads 2 awards · $772,546

    • 1R56HL161518-01A1Department: NIH department code

      Optimization of statin regimens for atherosclerotic cardiovascular disease prevention using polygenic risk scores and real-world evidence
      $595,048

      award amount
    • 5K01HL143109-05Department: NIH department code

      Characterization of response to lipid-modifying regimens for atherosclerotic cardiovascular disease using electronic health records
      $177,498

      award amount

18. England, Pamela Michael

    Leads 2 awards · $757,031

    • 3R01NS108404-04S1Department: NIH department code

      Investigating the effect of Nurr1 ligands in Alzheimer's Disease models
      $403,750

      award amount
    • 5R01NS108404-05Department: NIH department code

      Selective modulators for the nuclear receptor Nurr1
      $353,281

      award amount

19. Wang, Lei

    Leads 2 awards · $744,998

    • 5R01CA258300-02Department: NIH department code

      Covalent Protein Binders for Cancer Research and Therapy
      $394,164

      award amount
    • 5R01GM118384-07Department: NIH department code

      Adding new covalent bonds to proteins in live cells
      $350,834

      award amount

20. Alland, David

    Leads 1 award · $742,896

    • 5R01AI135124-04Department: NIH department code

      Identifying Optimal Treatment Strategies for Tuberculosis Treatment
      $742,896

      award amount

21. Irwin, John J.

    Leads 2 awards · $728,747

    • 5R01GM133836-04Department: NIH department code

      Ultra-large library docking for ligand discovery
      $389,597

      award amount
    • 5R01GM071896-17Department: NIH department code

      A Web-Based Automatic Virtual Screening System
      $339,150

      award amount

22. Degrado, William

    Leads 1 award · $666,047

    • 2R35GM122603-06Department: NIH department code

      Deciphering the relationship between structure, dynamics and function in helical bundle proteins
      $666,047

      award amount

23. Ferrin, Thomas E

    Leads 1 award · $664,692

    • 2R01GM129325-05Department: NIH department code

      ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling
      $664,692

      award amount

24. Duncan, D'anne S.

    Leads 1 award · $625,555

    • 5R25GM056847-24Department: NIH department code

      Maximizing Opportunities for Research Excellence
      $625,555

      award amount

25. Gestwicki, Jason E

    Leads 1 award · $624,434

    • 1T32GM145460-01Department: NIH department code

      Research Training in Chemistry and Chemical Biology
      $624,434

      award amount

26. Abate, Adam R.

    Leads 1 award · $619,168

    • 5R01EB019453-08Department: NIH department code

      Gigapixel digital PCR in Giant Unilamellar Vesicles
      $619,168

      award amount

27. Huttenhain, Ruth

    Leads 1 award · $613,700

    • 1R01DA056354-01Department: NIH department code

      Spatiotemporal signaling and trafficking of the mu-opioid receptor
      $613,700

      award amount

28. Florez, Jose Carlos

    Leads 1 award · $585,886

    • 5R01GM117163-07Department: NIH department code

      Discovery of Pharmacogenomic Biomarkers for OATP1B1 and OATP1B3
      $585,886

      award amount

29. Nicoll, Roger A

    Leads 1 award · $584,303

    • 5R01MH117139-05Department: NIH department code

      The synaptic cleft and glutamate receptor trafficking
      $584,303

      award amount

30. El-Samad, Hana

    Leads 1 award · $573,655

    • 5U01CA265697-02Department: NIH department code

      Synthetic circuits that drive infiltration of therapeutic T cells into immunologically cold tumors
      $573,655

      award amount

31. Arkin, Michelle

    Leads 1 award · $572,202

    • 5R01CA250459-03Department: NIH department code

      Discovery of Small Molecule Ligands for PHD1 Reader Domain of Histone Demethylase KDM5A
      $572,202

      award amount

32. Sali, Andrej

    Leads 2 awards · $541,660

    • 5R01GM083960-14Department: NIH department code

      IMP: Software for Hybrid Determination of Macromolecular Assembly Structures
      $342,380

      award amount
    • 3R01GM083960-14S1Department: NIH department code

      Equipment for IMP: Software for Hybrid Determination of Macromolecular Assembly Structures
      $199,280

      award amount

33. Renslo, Adam R

    Leads 1 award · $536,653

    • 5R01AI105106-10Department: NIH department code

      Chemical Methods for Ferrous Iron Dependent Drug Delivery
      $536,653

      award amount

34. Giacomini, Kathleen M

    Leads 1 award · $499,556

    • 5R01GM139875-02Department: NIH department code

      Characterizing the physiological and pharmacological roles of SLC22A24
      $499,556

      award amount

35. Bandyopadhyay, Sourav

    Leads 1 award · $493,346

    • 5R01CA238236-03Department: NIH department code

      Stress responses drive resistance and shape tumor evolution in EGFR mutant lung cancer
      $493,346

      award amount

36. Mullins, R Dyche

    Leads 1 award · $484,500

    • 5R35GM118119-07Department: NIH department code

      Assembly and function of cytoskeletal systems in eukaryotic and prokaryoticcells
      $484,500

      award amount

37. Fraser, James Solomon

    Leads 1 award · $460,275

    • 1R35GM145238-01Department: NIH department code

      Discovering and Manipulating Macromolecular Conformational Ensembles
      $460,275

      award amount

38. Correia, Maria Almira

    Leads 1 award · $452,200

    • 5R01GM044037-28Department: NIH department code

      Hepatic degradation of cytochrome P450 enzymes
      $452,200

      award amount

39. Wu, Lani F

    Leads 1 award · $429,843

    • 5R01CA184984-08Department: NIH department code

      Maximizing the predictive power of high-throughput, microscopy-based phenotypic screens
      $429,843

      award amount

40. Arkin, Michelle

    Leads 1 award · $416,655

    • 1R01GM147696-01Department: NIH department code

      Systematic stabilization of specific protein-protein interactions
      $416,655

      award amount

41. Williams, Allison H

    Leads 1 award · $412,077

    • 1R01GM144694-01Department: NIH department code

      Atomic-level probing of the peptidoglycan biosynthetic machinery in bacterial cell wall biogenesis
      $412,077

      award amount

42. Douglas, Shawn M

    Leads 1 award · $403,750

    • 5R35GM125027-05Department: NIH department code

      DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules
      $403,750

      award amount

43. Jura, Natalia

    Leads 1 award · $403,750

    • 5R35GM139636-02Department: NIH department code

      Structural and Functional Studies of HER Receptors
      $403,750

      award amount

44. Collisson, Eric

    Leads 1 award · $402,355

    • 5R01CA230263-04Department: NIH department code

      The structural and functional basis of MET exon 14 activation and acquired drug resistance
      $402,355

      award amount

45. Shokat, Kevan M.

    Leads 1 award · $395,637

    • 5R01CA244550-03Department: NIH department code

      Inhibitors of the G protein GNAS which drives pancreatic tumorigenesis
      $395,637

      award amount

46. Wells, James A

    Leads 1 award · $356,084

    • 5R01CA248323-03Department: NIH department code

      New protein engineering-based tools and technologies for characterizing cell surface proteolysis in cancer cells for novel neo-epitope biomarkers and drug targets
      $356,084

      award amount

47. Manglik, Aashish

    Leads 1 award · $331,512

    • 1R01GM138992-01A1Department: NIH department code

      Mechanisms of Smoothened Activation in Hedgehog Signaling
      $331,512

      award amount

48. Swaney, Danielle L

    Leads 1 award · $330,822

    • 5R01GM133981-04Department: NIH department code

      A universal multiplexing approach to unlock the hidden proteome
      $330,822

      award amount

49. Huang, Liusheng

    Leads 1 award · $201,875

    • 5R21AI153848-02Department: NIH department code

      Unbound piperaquine pharmacokinetic exposure in Ugandan pregnant women and children receiving malaria chemoprevention
      $201,875

      award amount

50. Deitchman, Amelia N

    Leads 1 award · $201,150

    • 5K23AI162249-02Department: NIH department code

      Clinical Pharmacology Approaches towards Accelerating HIV Cure Initiatives
      $201,150

      award amount

51. Chen, Xin

    Leads 1 award · $166,859

    • 5R01CA250227-02Department: NIH department code

      Investigating multifactorial beta-catenin activation in hepatocellular cancers
      $166,859

      award amount

52. Barbosa De Almeida, Ricardo Augusto

    Leads 1 award · $146,999

    • 5R01CA253017-02Department: NIH department code

      Synthetic epigenetic circuits: tunable cell fate switches controlled by dynamic and combinatorial inputs
      $146,999

      award amount

53. Bouhaddou, Mehdi

    Leads 1 award · $125,010

    • 1K99AI163868-01A1Department: NIH department code

      Decoding Viral Control of Host Kinase Signaling to Design Combination Therapy
      $125,010

      award amount

54. Newberry, Robert William

    Leads 1 award · $99,943

    • 5K99NS116679-02Department: NIH department code

      Biophysical Determinants of Physiological and Pathological alpha-Synuclein Membrane Interactions
      $99,943

      award amount

55. Mann, Samuel I

    Leads 1 award · $93,968

    • 5K99GM143529-02Department: NIH department code

      De novo design of functional metallocofactor-binding proteins
      $93,968

      award amount

56. Nikkanen, Joni

    Leads 1 award · $90,000

    • 1K99DK129763-01A1Department: NIH department code

      Dissecting Sex-Specific Metabolic Responses to Inflammation
      $90,000

      award amount

57. Morstein, Johannes

    Leads 1 award · $85,960

    • 5K00CA253758-03Department: NIH department code

      Lipid-based Cancer Therapeutics
      $85,960

      award amount

58. Ambrose, Andrew J

    Leads 1 award · $72,082

    • 1F32AG072822-01A1Department: NIH department code

      Deteriming the Role of Caspase Cleaved Tau in Alzheimer’s Disease
      $72,082

      award amount

59. Huycke, Tyler

    Leads 1 award · $67,582

    • 5F32DK128949-02Department: NIH department code

      Mechanochemical mechanisms of intestinal villus development and regeneration
      $67,582

      award amount

60. Jiang, Ziwen

    Leads 1 award · $67,582

    • 5F32GM139242-02Department: NIH department code

      Understanding the effects of p97 protein-protein interactions on cellular functions using antibody-based inhibitors
      $67,582

      award amount

61. Schnaider, Lee

    Leads 1 award · $67,582

    • 1F32GM143869-01A1Department: NIH department code

      Probing the rules of molecular recognition through the de novo design of proteins that bind small-molecule drugs.
      $67,582

      award amount

62. Greene, Eric Raymond

    Leads 1 award · $67,174

    • 1F32GM144982-01Department: NIH department code

      Connecting in vitro glutamine synthetase biophysics with the cellular environment
      $67,174

      award amount

63. Hatstat, Anna Katherine

    Leads 1 award · $67,174

    • 1F32GM147962-01Department: NIH department code

      A protein design- and structure-guided interrogation of signal transduction mechanisms
      $67,174

      award amount

64. Chalkley, Matthew

    Leads 1 award · $62,637

    • 5F32GM139379-03Department: NIH department code

      O2-Reactivity in De Novo Designed Mononuclear, Non-Heme Fe Proteins
      $62,637

      award amount

65. Chong, Megan Kaiulani

    Leads 1 award · $42,137

    • 5F31CA265136-02Department: NIH department code

      Error Correction in Mammalian Mitosis: Defining Physical Cues and Integration Mechanisms
      $42,137

      award amount

66. Zhu, Lawrence Yang

    Leads 1 award · $38,936

    • 5F31NS122434-02Department: NIH department code

      Probing the Role of the LRRK2 GTPase in Parkinson's Disease
      $38,936

      award amount

67. Hoppe, Nick

    Leads 1 award · $38,785

    • 1F31HL164045-01Department: NIH department code

      Molecular mechanisms of proton-sensing in CO2-dependent breathing
      $38,785

      award amount

68. Harshman, Lana

    Leads 1 award · $23,910

    • 5F31HG011568-03Department: NIH department code

      Determining the influence of 3D chromatin structure on human evolution
      $23,910

      award amount

69. Kirkemo, Lisa

    Leads 1 award · $17,953

    • 5F31CA247527-03Department: NIH department code

      Mechanistic Insights and Diagnostic Applications for Hypoxia-Induced Vasorin in Pancreatic Cancer
      $17,953

      award amount

70. Schneider, Samuel H.

    Leads 1 award · $17,874

    • 5F32GM142183-02Department: NIH department code

      Development of a Mechanism and Structure-Guided Methodology for De Novo Enzyme Design
      $17,874

      award amount