Physiology at University of Michigan

Leads a grant in this department

46 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Ormond A MacDougald

   Leads 4 awards · $1,945,930

   • 2R01DK125513-04A1Department: NIH department code

     Mechanisms of adipocyte loss in laminopathy-induced lipodystrophy in mice and humans

     Principal investigators: Ormond A MacDougald (contact PI), Elif Arioglu Oral

     $669,659

     award amount
   • 1R01DK137798-01Department: NIH department code

     Metabolism and functions of bone marrow adipose tissue in the marrow niche
     $469,065

     award amount
   • 5R01DK130879-03Department: NIH department code

     Effects of Wnt/β-catenin signaling on adipocytes
     $426,816

     award amount
   • 5R01DK121759-05Department: NIH department code

     Mechanisms by which adipocytes adapt to cool environmental temperatures
     $380,390

     award amount

2. Scott Pletcher

   Leads 4 awards · $1,937,480

   • 4R33AG078428-03Department: NIH department code

     Systems and methods for molecular dissection of socio-environmental effects on aging
     $568,443

     award amount
   • 5T32AG000114-40Department: NIH department code

     Career Training in the Biology of Aging
     $535,930

     award amount
   • 2R01AG030593-16Department: NIH department code

     Modulation of aging by Sensory Perception
     $455,571

     award amount
   • 5R37AG051649-09Department: NIH department code

     Modulation of aging through mechanisms of nutrient demand and reward
     $377,536

     award amount

3. Shawn Xu

   Leads 4 awards · $1,639,140

   • 5R01NS118769-05Department: NIH department code

     An unexpected role of glutamate receptors in the peripheral nervous system

     Principal investigators: Shawn Xu (contact PI), Bo Duan

     $497,691

     award amount
   • 5R35GM126917-07Department: NIH department code

     Neural and genetic mechanisms underlying behavior in C. elegans
     $427,777

     award amount
   • 5R01AG067753-05Department: NIH department code

     Chemosensation and longevity in C. elegans
     $368,862

     award amount
   • 5R01DC018167-05Department: NIH department code

     Neural and genetic mechanisms underlying mechanosensation in C. elegans
     $344,810

     award amount

4. Suzanne M Moenter

   Leads 4 awards · $1,617,013

   • 5R37HD034860-28Department: NIH department code

     Cellular and molecular bases for rhythmic GnRH release
     $568,853

     award amount
   • 5R01HD104345-04Department: NIH department code

     Development of the GnRH neuronal network and effects of prenatal androgen exposure
     $429,969

     award amount
   • 5R01HD041469-23Department: NIH department code

     Central Actions of Estrogens: Effects on GnRH Neurons
     $423,343

     award amount
   • 2T32HD079342-11Department: NIH department code

     Career Training in Reproductive Biology
     $194,848

     award amount

5. Longhua Guo

   Leads 2 awards · $1,599,000

   • 1DP2AG093207-01Department: NIH department code

     Turning back biological clock: mechanisms of age reversal in a whole organism
     $1,404,000

     award amount
   • 5R21AG084959-02Department: NIH department code

     Imaging spatial transcriptome at single cell resolution to study eye regeneration in old age
     $195,000

     award amount

6. Yatrik M Shah

   Leads 4 awards · $1,325,389

   • 5R01DK095201-13Department: NIH department code

     Control of iron absorption by intestinal HIF2 in iron and hematological disorders
     $488,462

     award amount
   • 5R01CA245546-05Department: NIH department code

     Understanding the mechanisms of iron addiction in colon cancer
     $429,787

     award amount
   • 5R01CA148828-14Department: NIH department code

     The role of HIF2alpha in colon carcinogenesis
     $343,473

     award amount
   • 3R01CA245546-05S1Department: NIH department code

     Understanding the mechanisms of iron addiction in colon cancer
     $63,667

     award amount

7. Jun Hee Lee

   Leads 2 awards · $1,316,968

   • 5UH3CA268091-04Department: NIH department code

     Seq-Scope: Microscopic Examination of Spatial Single Cell Transcriptome in Cell and Tissue Senescence
     $779,599

     award amount
   • 5R01AG079163-07Department: NIH department code

     Sestrins-mediated integration of leucine and exercise benefits for mitochondrial homeostasis

     Principal investigators: Jun Hee Lee (contact PI), Myungjin Kim

     $537,369

     award amount

8. William E Rainey

   Leads 2 awards · $1,150,621

   • 5R01DK106618-09Department: NIH department code

     Adrenal Origins of Aldosterone Excess
     $603,055

     award amount
   • 2R01DK043140-25A1Department: NIH department code

     Mechanisms Leading to Adrenal Zonation
     $547,566

     award amount

9. Costas Andreas Lyssiotis

   Leads 3 awards · $1,102,241

   • 5R01CA248160-05Department: NIH department code

     Stromal metabolism promotes therapeutic resistance in pancreatic cancer
     $379,104

     award amount
   • 5R01CA244931-05Department: NIH department code

     Targeting metabolic stress to induce pancreatic tumor cell death
     $370,329

     award amount
   • 5R37CA237421-05Department: NIH department code

     Intratumoral Metabolic Crosstalk Promotes Therapeutic Resistance in Pancreatic Cancer
     $352,808

     award amount

10. Daniel A Beard

    Leads 2 awards · $955,083

    • 1R01HL173346-01Department: NIH department code

      Multi-Scale Systems Analysis of Metabolic and Mechanical Determinants of Reserve Cardiac Power Output
      $625,467

      award amount
    • 5T32GM150581-02Department: NIH department code

      Systems and Integrative Biology Training Program
      $329,616

      award amount

11. Ken Inoki

    Leads 2 awards · $951,179

    • 5R01DK124709-03Department: NIH department code

      Lysosomal cholesterol-dependent anabolic regulation
      $500,838

      award amount
    • 5R01GM145631-03Department: NIH department code

      Molecular mechanism of Rheb-dependent mTORC1 regulation
      $450,341

      award amount

12. Liangyou Rui

    Leads 2 awards · $944,895

    • 5R01DK114220-08Department: NIH department code

      The role of hypothalamic Slug in the regulation of leptin sensitivity, energy balance, and body weight
      $489,625

      award amount
    • 5R01DK130111-03Department: NIH department code

      Role of adipose mRNA modifications in metabolic disease
      $455,270

      award amount

13. David Sept

    Leads 1 award · $914,504

    • 5K12GM111725-09Department: NIH department code

      Michigan IRACDA: Diversifying the Future Academic Workforce in STEM

      Principal investigators: David Sept (contact PI), Susan V Brooks

      $914,504

      award amount

14. Jun Wu

    Leads 2 awards · $814,654

    • 5R01AA028761-04Department: NIH department code

      A novel cholinergic circuitry in alcoholic liver disease (NIAAA)
      $413,297

      award amount
    • 5R01DK107583-09Department: NIH department code

      The role of immune-adipocyte cholinergic signaling during metabolic adaptation and dysfunction
      $401,357

      award amount

15. Peng Li

    Leads 2 awards · $786,318

    • 5R01AT011652-04Department: NIH department code

      Dissecting neural circuits for breathing patterns
      $412,300

      award amount
    • 5R01HL156989-03Department: NIH department code

      Neural circuit control of sighing
      $374,018

      award amount

16. Matthias Christof Truttmann

    Leads 2 awards · $717,983

    • 5R35GM142561-04Department: NIH department code

      Conserved regulation of proteostasis by post-translational protein AMPylation
      $384,099

      award amount
    • 3R35GM142561-04S1Department: NIH department code

      Conserved regulation of proteostasis by post-translational protein AMPylation
      $333,884

      award amount

17. Carol Fuzeti Elias

    Leads 2 awards · $624,037

    • 5R01HD106962-02Department: NIH department code

      Sex-specific role of androgen signaling in neuroendocrine-behavior interface
      $412,349

      award amount
    • 5T32NS076401-24Department: NIH department code

      Early Stage Training in the Neurosciences
      $211,688

      award amount

18. Susan V Brooks

    Leads 1 award · $572,203

    • 1R01AG086251-01Department: NIH department code

      Preservation of muscle function through Schwann cell regulation of motor unit expansion
      $572,203

      award amount

    Also a principal investigator on 5K12GM111725-09, led by David Sept.

19. Lei Yin

    Leads 1 award · $548,258

    • 5R01DK099593-09Department: NIH department code

      Significance and mechanisms of hepatic ChREBPα induction via post-translational modifications in diet-induced NASH
      $548,258

      award amount

20. Linda C. Samuelson

    Leads 1 award · $488,783

    • 5R01DK126451-03Department: NIH department code

      Wnt Pathway Regulation of Gastric Stem Cell Function
      $488,783

      award amount

21. Scott F Leiser

    Leads 2 awards · $479,339

    • 5R01AG075061-03Department: NIH department code

      Flavin-containing monooxygenases in endogenous metabolism and aging
      $390,347

      award amount
    • 3R01AG075061-03S1Department: NIH department code

      Flavin-containing monooxygenases in endogenous metabolism and aging
      $88,992

      award amount

22. Jayakrishnan Nandakumar

    Leads 1 award · $473,457

    • 5R01HD108809-03Department: NIH department code

      Mechanisms of chromosome motility during mammalian meiosis
      $473,457

      award amount

23. Michael Mark Alexander Sutton

    Leads 1 award · $418,879

    • 5R01NS097498-08Department: NIH department code

      Trans-synaptic control of presynaptic neurotransmitter release
      $418,879

      award amount

24. Christian Richard Burgess

    Leads 1 award · $402,367

    • 5R01DK129366-04Department: NIH department code

      Elucidating the role for MCH neurons in feeding behavior and responses to sensory food cues
      $402,367

      award amount

25. Anthony G Vecchiarelli

    Leads 1 award · $381,935

    • 1R35GM152128-01Department: NIH department code

      Coordinated Spatial Organization in Bacteria
      $381,935

      award amount

26. Roger D. Cone

    Leads 1 award · $378,974

    • 5R01DK125830-04Department: NIH department code

      Role of HDAC6 in the Regulation of Energy Homeostasis and Leptin Sensitivity
      $378,974

      award amount

27. Juilee Rege

    Leads 1 award · $378,450

    • 1R01HL174676-01Department: NIH department code

      Genetic Causes of Endocrine Hypertension in Black Americans
      $378,450

      award amount

28. Morgan Desantis

    Leads 1 award · $375,088

    • 5R35GM146739-03Department: NIH department code

      Mechanisms of dynein regulation
      $375,088

      award amount

29. Elise L Savier

    Leads 1 award · $246,355

    • 5R00EY031783-04Department: NIH department code

      Integration of visual information and behavioral modulation in the superior colliculus
      $246,355

      award amount

30. Daniel E Michele

    Leads 1 award · $166,116

    • 5T32HL125242-10Department: NIH department code

      Training Program in Translational Cardiovascular Research and Entrepreneurship
      $166,116

      award amount

31. Megan Deanna Radyk

    Leads 1 award · $125,000

    • 1K99GM159354-01A1Department: NIH department code

      Metabolic regulation of pancreatic metaplasia and neoplasia
      $125,000

      award amount

32. Ajay Bhat

    Leads 1 award · $116,972

    • 1K99AG083058-01A1Department: NIH department code

      Mechanistic understanding of host-microbe interactions in regulating stress response and lifespan
      $116,972

      award amount

33. Lloyd Phillip Ruiz

    Leads 1 award · $52,082

    • 1R36AG087309-01Department: NIH department code

      Lamin A/C is required for maintaining subsynaptic myonuclei integrity
      $52,082

      award amount

34. Mirella Hernandez

    Leads 1 award · $43,555

    • 5F99NS135768-02Department: NIH department code

      Perception of Dead Conspecifics modulates neural signaling and lifespan in Caenorhabditis elegans
      $43,555

      award amount

35. Chrystian David Phillips

    Leads 1 award · $42,652

    • 5F31HD110102-02Department: NIH department code

      A role for hypothalamic astrocytes in neural circuits controlling reproduction
      $42,652

      award amount

36. Kate Matthys Van Pelt

    Leads 1 award · $42,652

    • 5F31NS127485-03Department: NIH department code

      Elucidating the impact of FIC-1/FICD-mediated AMPylation on polyglutamine aggregation dynamics and toxicity
      $42,652

      award amount

37. Elizabeth Sarah Kitto

    Leads 1 award · $42,575

    • 5F31AG084146-02Department: NIH department code

      Determining the neural mechanisms of mechanosensory food perception in DR-mediated longevity
      $42,575

      award amount

38. Jessica Nanda Maung

    Leads 1 award · $42,099

    • 5F31DK135181-02Department: NIH department code

      Mechanisms of adipocyte loss in mouse models of familial partial lipodystrophy 2
      $42,099

      award amount

39. Brandon Anthony Toth

    Leads 1 award · $42,094

    • 1F31NS132434-01A1Department: NIH department code

      Monoaminergic and limbic systems underlying narcolepsy-cataplexy
      $42,094

      award amount

40. Brandon Chen

    Leads 1 award · $42,094

    • 5F99CA284256-02Department: NIH department code

      Inter-organellar communication in metabolic reprogramming of colorectal cancer
      $42,094

      award amount

41. Jessica Liang

    Leads 1 award · $42,094

    • 1F31HL175884-01Department: NIH department code

      Elucidating the Role of Notch/HES Signaling in Alveolar Epithelial Type II to Type I Cell Differentiation
      $42,094

      award amount

42. Narges Pourmandi

    Leads 1 award · $42,094

    • 1F31HL172674-01Department: NIH department code

      Defining the metabolic regulation of erythropoiesis
      $42,094

      award amount

43. Nicholas David Urban

    Leads 1 award · $42,094

    • 1F31AG085891-01A1Department: NIH department code

      Elucidating the roles of AMPylation and TGF-Beta signaling on eliciting the pro-health and longevity benefits of dietary restriction
      $42,094

      award amount

44. Katherine L Furman

    Leads 1 award · $41,464

    • 5F31DK135283-02Department: NIH department code

      Elucidating MCH neural circuitry underlying consummatory behavior
      $41,464

      award amount

45. Nicole Collins

    Leads 1 award · $41,362

    • 5F31HL165681-03Department: NIH department code

      Pathways of Succinate Accumulation and Adenine Nucleotide Depletion in Cardiac Ischemia
      $41,362

      award amount

46. Heather Marie Giza

    Leads 1 award · $34,808

    • 5F31CA281241-02Department: NIH department code

      Defining cell intrinsic and extrinsic regulators of ferroptosis in pancreatic cancer
      $34,808

      award amount

Co-investigators

Named as principal investigators on these awards, which someone else leads. They may belong to another department or institution: their own, below, comes from the awards they lead.

• Elif Arioglu Oral

  Co-investigator on 2R01DK125513-04A1, led by Ormond A MacDougald

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Myungjin Kim

  Co-investigator on 5R01AG079163-07, led by Jun Hee Lee

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.

• Bo Duan

  Co-investigator on 5R01NS118769-05, led by Shawn Xu

  Own institution and department: not known. ScienceDex has no NIH award this person leads as contact PI.