Genetics at University of Pennsylvania

Leads a grant in this department

30 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Kaestner, Klaus H

   Leads 4 awards · $4,560,225

   • 5U01DK123594-03Department: NIH department code

     The Human Pancreas Analysis Program for Type 2 Diabetes
     $3,000,000

     award amount
   • 1U01DK134995-01Department: NIH department code

     The role of senescent beta cells in T1D and T2D
     $758,532

     award amount
   • 5R01CA249929-08Department: NIH department code

     Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression
     $533,446

     award amount
   • 3U01DK123594-03S1Department: NIH department code

     The Human Pancreas Analysis Program for Type 2 Diabetes
     $268,247

     award amount

2. Phillips-Cremins, Jennifer Elizabeth

   Leads 3 awards · $2,069,032

   • 5DP1MH129957-02Department: NIH department code

     From 3D genomes to neural connectomes: Higher-order chromatin mechanisms encoding long-term memory
     $1,137,500

     award amount
   • 5R01MH120269-04Department: NIH department code

     Connecting 3D genome misfolding to transcriptional silencing in fragile X syndrome
     $471,441

     award amount
   • 5R01NS114226-03Department: NIH department code

     Elucidating the 3-D epigenetic determinants of activity-dependent gene expression in mammalian neurons
     $460,091

     award amount

3. Jain, Rajan

   Leads 2 awards · $1,729,300

   • 5R01GM137425-04Department: NIH department code

     Decoding the bridges and barriers to cellular reprogramming and lineage identity
     $1,100,618

     award amount
   • 5U01DA052715-03Department: NIH department code

     Single-cell dissection of chromatin architecture mechanisms connecting pathologic instability and transcriptional silencing
     $628,682

     award amount

4. Gonzalez Camara, Pablo

   Leads 2 awards · $1,614,040

   • 1RF1MH130553-01Department: NIH department code

     CAJAL: A computational framework for the combined morphometric, transcriptomic, and physiological analysis of cells
     $1,254,662

     award amount
   • 1U01CA269409-01A1Department: NIH department code

     A data-driven bioinformatics platform for the design and analysis of multiplexed antibody-based cytometry experiments in cancer research
     $359,378

     award amount

5. Epstein, Douglas J

   Leads 3 awards · $1,274,734

   • 5R01DC006254-19Department: NIH department code

     Role of Gas2 in cytoskeletal architecture, support cell stiffness, and cochlear function
     $445,957

     award amount
   • 5T32GM008216-36Department: NIH department code

     Predoctoral Training Program in Genetics
     $416,289

     award amount
   • 5R01NS039421-22Department: NIH department code

     Transcriptional control of Sonic hedgehog signaling
     $412,488

     award amount

6. Kannan, Sreeram

   Leads 1 award · $1,210,000

   • 5U01HG012047-02Department: NIH department code

     Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics
     $1,210,000

     award amount

7. Blobel, Gerd A

   Leads 1 award · $1,108,388

   • 5U01DK127405-03Department: NIH department code

     Engineering and Imaging 3D genome structure-function dynamics across time scales
     $1,108,388

     award amount

8. Zhou, Zhaolan

   Leads 2 awards · $1,057,301

   • 5R01NS102731-05Department: NIH department code

     Pathogenic Studies of CDKL5 Disorder
     $538,031

     award amount
   • 5R01NS081054-09Department: NIH department code

     Understanding the Pathogenic Mechanisms of Rett Syndrome
     $519,270

     award amount

9. Vahedi, Golnaz

   Leads 2 awards · $962,428

   • 5U01DK127768-03Department: NIH department code

     Dissecting transcriptomics and epigenomic signatures of immune cells in type 1 diabetes
     $510,739

     award amount
   • 5R01HL145754-04Department: NIH department code

     Critical role of TCF-1 on the epigenetic identity of memory T cells
     $451,689

     award amount

10. Murray, John Isaac

    Leads 2 awards · $846,344

    • 5R01HD105819-02Department: NIH department code

      Comparing cell types across mutants and species at single cell resolution
      $443,844

      award amount
    • 5R35GM127093-05Department: NIH department code

      Decoding lineage and fate specification in the C. elegans embryo
      $402,500

      award amount

11. Cuchel, Marina

    Leads 1 award · $748,107

    • 5R01HL148769-04Department: NIH department code

      Physiological and therapeutic effects of ANGPTL3 variants in mice and humans
      $748,107

      award amount

12. Barash, Yoseph

    Leads 2 awards · $734,334

    • 1R01GM147739-01Department: NIH department code

      Identifying regulatory uORFs as a targetable axis for hereditary disease
      $394,453

      award amount
    • 5R01LM013437-03Department: NIH department code

      Methods for improving clinical diagnostic by detection, prediction, interpretation and prioritization of aberrant transcriptome variations
      $339,881

      award amount

13. Sundaram, Meera

    Leads 1 award · $657,567

    • 5R35GM136315-03Department: NIH department code

      Building and shaping narrow epithelial tubes in C. elegans
      $657,567

      award amount

14. Joyce, Eric F.

    Leads 2 awards · $646,250

    • 5R35GM128903-05Department: NIH department code

      Regulation of chromatin folding in space and time
      $402,500

      award amount
    • 1R21HD107261-01A1Department: NIH department code

      Evaluating novel architectural proteins as therapeutic targets for cohesin dysfunction
      $243,750

      award amount

15. Herlyn, Meenhard F

    Leads 2 awards · $612,854

    • 5R01CA238237-03Department: NIH department code

      Understanding and Overcoming Resistance to BRAF/MEK Kinase Inhibitors in Melanoma
      $493,785

      award amount
    • 3R01CA238237-03S1Department: NIH department code

      Understanding and Overcoming Resistance to BRAF/MEK Kinase Inhibitors in Melanoma
      $119,069

      award amount

16. Klein, Teri Ellen

    Leads 1 award · $560,000

    • 5U24HG010862-03Department: NIH department code

      Pharmacogenomics Clinical Annotation Tool (PharmCAT)
      $560,000

      award amount

17. Radhakrishnan, Ravi

    Leads 1 award · $555,518

    • 5U01CA227550-05Department: NIH department code

      A plasticity and reprogramming paradigm for therapy resistance at the single cell level
      $555,518

      award amount

18. Tishkoff, Sarah Anne

    Leads 1 award · $534,363

    • 5R35GM134957-03Department: NIH department code

      Integrative Genomic Analyses of Human Evolution and Adaptation in Africa
      $534,363

      award amount

19. Kamberov, Yana G

    Leads 1 award · $438,426

    • 5R01AR077690-03Department: NIH department code

      Genetic and Cellular Mechanisms of Engrailed-1 Regulation and Function in Eccrine Sweat Gland Development
      $438,426

      award amount

20. Gao, Ziyue

    Leads 1 award · $406,250

    • 1R35GM146810-01Department: NIH department code

      Mechanisms and consequences of sequence context-dependency of human mutation rate
      $406,250

      award amount

21. Mathieson, Iain Neil

    Leads 1 award · $402,433

    • 5R35GM133708-04Department: NIH department code

      Polygenic prediction and evolution of complex traits
      $402,433

      award amount

22. Hart, Michael P

    Leads 1 award · $391,250

    • 1R35GM146782-01Department: NIH department code

      Molecular coordination of adhesion molecules in foraging behaviors and circuits
      $391,250

      award amount

23. Bucan, Maja

    Leads 1 award · $295,434

    • 5R25HG010323-05Department: NIH department code

      Diversity Action Plan at the University of Pennsylvania (Penn) Genomics Program (DAPPG)
      $295,434

      award amount

24. Jongens, Thomas A

    Leads 1 award · $240,000

    • 1R21MH126257-01A1Department: NIH department code

      Determining whether metabolic and mitochondrial pathophysiology are a common feature of three distinct genetic models of ASD
      $240,000

      award amount

25. Zaidi, Syed Arslan Abbas

    Leads 1 award · $37,766

    • 5K99GM137076-02Department: NIH department code

      Leveraging human evolutionary history to improve our understanding of complex disease architecture
      $37,766

      award amount

26. Harke, Jailynn Alyse

    Leads 1 award · $34,096

    • 5F31HD103375-03Department: NIH department code

      Probing the three-dimensional organization of enhancer-promoter communication
      $34,096

      award amount

27. Wei, Alex Tianjiun

    Leads 1 award · $26,179

    • 5F31HG011429-03Department: NIH department code

      Dissecting Gene Regulatory Roles of TET Enzymes and 5-hydroxymethylcytosine in Mammalian Active DNA Demethylation
      $26,179

      award amount

28. Kolev, Hannah

    Leads 1 award · $24,049

    • 5F31DK126404-03Department: NIH department code

      Elucidating the role of H3K27me3 demethylation in the intestinal epithelium
      $24,049

      award amount

29. Bahl, Varun

    Leads 1 award · $18,803

    • 5F31DK126231-03Department: NIH department code

      Elucidating the role of G6PC2 in glucose-regulation of glucagon secretion in pancreatic alpha-cells
      $18,803

      award amount

30. Luppino, Jennifer Mary

    Leads 1 award · $7,823

    • 5F31HD102084-03Department: NIH department code

      Elucidating the role of chromatin architecture in the pathophysiology of Cornelia de Lange Syndrome
      $7,823

      award amount