Genetics at University of Pennsylvania

Leads a grant in this department

25 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Kaestner, Klaus H

   Leads 3 awards · $4,254,790

   • 5U01DK123594-04Department: NIH department code

     The Human Pancreas Analysis Program for Type 2 Diabetes
     $3,000,000

     award amount
   • 5U01DK134995-02Department: NIH department code

     The role of senescent beta cells in T1D and T2D
     $721,344

     award amount
   • 5R01CA249929-09Department: NIH department code

     Innovative Genetic Approaches to Enhance Liver Repopulation and Reduce Cancer Risk and Progression
     $533,446

     award amount

2. Phillips-Cremins, Jennifer Elizabeth

   Leads 4 awards · $2,337,873

   • 5DP1MH129957-03Department: NIH department code

     From 3D genomes to neural connectomes: Higher-order chromatin mechanisms encoding long-term memory
     $1,137,500

     award amount
   • 5R01NS114226-04Department: NIH department code

     Elucidating the 3-D epigenetic determinants of activity-dependent gene expression in mammalian neurons
     $507,673

     award amount
   • 5R01MH120269-05Department: NIH department code

     Connecting 3D genome misfolding to transcriptional silencing in fragile X syndrome
     $433,900

     award amount
   • 1S10OD032363-01A1Department: NIH department code

     Linking epigenetics to electrophysiology using high-throughput microelectrode array-based hardware with simultaneous optogenetic activation
     $258,800

     award amount

3. Jain, Rajan

   Leads 2 awards · $1,705,794

   • 5R01GM137425-05Department: NIH department code

     Decoding the bridges and barriers to cellular reprogramming and lineage identity
     $1,085,190

     award amount
   • 5U01DA052715-04Department: NIH department code

     Single-cell dissection of chromatin architecture mechanisms connecting pathologic instability and transcriptional silencing
     $620,604

     award amount

4. Song, Hongjun

   Leads 1 award · $1,210,000

   • 5U01HG012047-03Department: NIH department code

     Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics
     $1,210,000

     award amount

5. Epstein, Douglas J

   Leads 3 awards · $1,178,546

   • 5R01DC006254-20Department: NIH department code

     Role of Gas2 in cytoskeletal architecture, support cell stiffness, and cochlear function
     $445,957

     award amount
   • 5R01NS039421-23Department: NIH department code

     Transcriptional control of Sonic hedgehog signaling
     $412,488

     award amount
   • 5T32GM008216-37Department: NIH department code

     Predoctoral Training Program in Genetics
     $320,101

     award amount

6. Blobel, Gerd A

   Leads 1 award · $1,122,096

   • 5U01DK127405-04Department: NIH department code

     Engineering and Imaging 3D genome structure-function dynamics across time scales
     $1,122,096

     award amount

7. Vahedi, Golnaz

   Leads 2 awards · $952,603

   • 5U01DK127768-04Department: NIH department code

     Dissecting transcriptomics and epigenomic signatures of immune cells in type 1 diabetes
     $500,914

     award amount
   • 5R01HL145754-05Department: NIH department code

     Critical role of TCF-1 on the epigenetic identity of memory T cells
     $451,689

     award amount

8. Barash, Yoseph

   Leads 3 awards · $820,386

   • 5R01GM147739-02Department: NIH department code

     Identifying regulatory uORFs as a targetable axis for hereditary disease
     $404,023

     award amount
   • 5R01LM013437-04Department: NIH department code

     Methods for improving clinical diagnostic by detection, prediction, interpretation and prioritization of aberrant transcriptome variations
     $339,916

     award amount
   • 3R01GM147739-02S1Department: NIH department code

     Identifying regulatory uORFs as a targetable axis for hereditary disease
     $76,447

     award amount

9. Kim, Dokyoon

   Leads 1 award · $804,781

   • 1R01HL169458-01Department: NIH department code

     Methods for Enhancing Polygenic Risk Prediction Models for Complex Disease
     $804,781

     award amount

10. Hart, Michael P

    Leads 2 awards · $803,125

    • 5R35GM146782-02Department: NIH department code

      Molecular coordination of adhesion molecules in foraging behaviors and circuits
      $406,250

      award amount
    • 1R01NS129736-01Department: NIH department code

      Genetic and molecular regulation of experience-dependent structural plasticity
      $396,875

      award amount

11. Henao-Mejia, Jorge

    Leads 1 award · $772,175

    • 1R01AI168136-01A1Department: NIH department code

      3D genome organization of the Ets1-Fli1 locus controls allergic responses
      $772,175

      award amount

12. Jongens, Thomas A

    Leads 2 awards · $739,013

    • 1R01NS129903-01A1Department: NIH department code

      Mitochondrial dysfunction in Fragile X: Mechanisms and treatments
      $539,750

      award amount
    • 5R21MH126257-02Department: NIH department code

      Determining whether metabolic and mitochondrial pathophysiology are a common feature of three distinct genetic models of ASD
      $199,263

      award amount

13. Joyce, Eric F.

    Leads 2 awards · $690,625

    • 2R35GM128903-06Department: NIH department code

      Regulation of chromatin folding in space and time
      $487,500

      award amount
    • 5R21HD107261-02Department: NIH department code

      Evaluating novel architectural proteins as therapeutic targets for cohesin dysfunction
      $203,125

      award amount

14. Sundaram, Meera

    Leads 1 award · $657,567

    • 5R35GM136315-04Department: NIH department code

      Building and shaping narrow epithelial tubes in C. elegans
      $657,567

      award amount

15. Herlyn, Meenhard F

    Leads 2 awards · $610,472

    • 5R01CA238237-04Department: NIH department code

      Understanding and Overcoming Resistance to BRAF/MEK Kinase Inhibitors in Melanoma
      $493,786

      award amount
    • 3R01CA238237-04S1Department: NIH department code

      Understanding and Overcoming Resistance to BRAF/MEK Kinase Inhibitors in Melanoma
      $116,686

      award amount

16. Tishkoff, Sarah Anne

    Leads 1 award · $534,258

    • 5R35GM134957-04Department: NIH department code

      Integrative Genomic Analyses of Human Evolution and Adaptation in Africa
      $534,258

      award amount

17. Zhou, Zhaolan

    Leads 1 award · $520,316

    • 5R01NS081054-10Department: NIH department code

      Understanding the Pathogenic Mechanisms of Rett Syndrome
      $520,316

      award amount

18. Murray, John Isaac

    Leads 1 award · $443,844

    • 5R01HD105819-03Department: NIH department code

      Comparing cell types across mutants and species at single cell resolution
      $443,844

      award amount

19. Kamberov, Yana G

    Leads 1 award · $442,855

    • 5R01AR077690-04Department: NIH department code

      Genetic and Cellular Mechanisms of Engrailed-1 Regulation and Function in Eccrine Sweat Gland Development
      $442,855

      award amount

20. Gao, Ziyue

    Leads 1 award · $406,250

    • 5R35GM146810-02Department: NIH department code

      Mechanisms and consequences of sequence context-dependency of human mutation rate
      $406,250

      award amount

21. Mathieson, Iain Neil

    Leads 1 award · $402,433

    • 5R35GM133708-05Department: NIH department code

      Polygenic prediction and evolution of complex traits
      $402,433

      award amount

22. Gonzalez Camara, Pablo

    Leads 1 award · $374,852

    • 5U01CA269409-02Department: NIH department code

      A data-driven bioinformatics platform for the design and analysis of multiplexed antibody-based cytometry experiments in cancer research
      $374,852

      award amount

23. Schmidt, Helen Frances

    Leads 1 award · $69,500

    • 1F32GM151778-01Department: NIH department code

      Cell-type specific assembly of apical extracellular matrices
      $69,500

      award amount

24. Hill, Connor MacKenzie

    Leads 1 award · $47,694

    • 5F31CA265257-02Department: NIH department code

      The molecular function of the oncogenic NAB2-STAT6 fusion protein
      $47,694

      award amount

25. Park, Daniel Sungjoo

    Leads 1 award · $35,043

    • 5F30HD104360-02Department: NIH department code

      Investigating cohesin regulators to target Cornelia de Lange Syndrome
      $35,043

      award amount