Biochemistry at Yale University

Leads a grant in this department

57 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Breaker, Ronald R

   Leads 2 awards · $2,522,239

   • 5P01GM022778-42Department: NIH department code

     Structural bases of the functions of RNA-protein machines
     $1,287,624

     award amount
   • 1R01AI136794-01Department: NIH department code

     Exploiting Riboswitch Sensors to Reveal Antibiotics Uptake and Retention in Gram Negative Bacteria
     $1,234,615

     award amount

2. Baserga, Susan J

   Leads 3 awards · $2,128,969

   • 5T32GM007223-44Department: NIH department code

     Predoctoral Program in Cellular and Molecular Biology
     $1,413,898

     award amount
   • 5R01GM115710-04Department: NIH department code

     Key factors in human ribosome biogenesis
     $397,447

     award amount
   • 5R01GM122926-02Department: NIH department code

     A New Role for the PAX9 Protein in Ribosome Biogenesis
     $317,624

     award amount

3. Nairn, Angus C.

   Leads 1 award · $1,544,774

   • 5P30DA018343-14Department: NIH department code

     Yale/NIDA Neuroproteomics Center
     $1,544,774

     award amount

4. Crews, Craig M

   Leads 2 awards · $1,348,761

   • 5R35CA197589-04Department: NIH department code

     Inducing Protein Degradation: A New Pharmaceutical Paradigm
     $877,462

     award amount
   • 2T32GM067543-16Department: NIH department code

     Predoctoral Training at the Interface Chemistry and Biology
     $471,299

     award amount

5. Holley, Scott A

   Leads 3 awards · $1,137,338

   • 5R01HD092361-02Department: NIH department code

     The cross-scale biomechanics of tissue morphogenesis
     $418,750

     award amount
   • 1R01GM127876-01Department: NIH department code

     The Molecular Biophysics and Tissue Biomechanics of Somite Morphogenesis
     $383,588

     award amount
   • 1R01GM129149-01Department: NIH department code

     EMT, Tailbud Biomechanics and Spinal Column Symmetry
     $335,000

     award amount

6. Hochstrasser, Mark W

   Leads 3 awards · $1,056,813

   • 5R01GM053756-23Department: NIH department code

     Functions and Mechanisms of Deubiquitinating Enzymes
     $361,800

     award amount
   • 5R37GM046904-28Department: NIH department code

     Degradation of Short Lived Regulatory Protein in Yeast
     $355,622

     award amount
   • 5R01GM083050-11Department: NIH department code

     Function and Assembly of Eukaryotic Proteasomes
     $339,391

     award amount

7. Carlson, John R

   Leads 3 awards · $1,039,582

   • 5R01DC002174-32Department: NIH department code

     Genetic and Molecular Analysis of Olfaction
     $352,594

     award amount
   • 5R01DC004729-18Department: NIH department code

     Analysis of Chemosensory Receptor Genes
     $343,549

     award amount
   • 5R01DC011697-15Department: NIH department code

     Analysis of a large family of taste receptors
     $343,439

     award amount

8. Soll, Dieter

   Leads 1 award · $1,033,951

   • 5R35GM122560-02Department: NIH department code

     Studies of Transfer RNA
     $1,033,951

     award amount

9. Gerstein, Mark Bender

   Leads 3 awards · $1,014,345

   • 5R01HG008126-03Department: NIH department code

     Prioritizing rare variants associated with cancer using non-coding annotation
     $769,592

     award amount
   • 5U01EB023686-03Department: NIH department code

     Methods and Software to Enhance Genomic Privacy and Sharing of RNA-Seq Data
     $242,576

     award amount
   • 3U01EB023686-02S1Department: NIH department code

     Methods and Software to Enhance Genomic Privacy and Sharing of RNA-Seq Data
     $2,177

     award amount

10. Pollard, Thomas D.

    Leads 2 awards · $962,259

    • 5R01GM026338-40Department: NIH department code

      Molecular Mechanisms of Cellular Motility
      $520,310

      award amount
    • 5R01GM026132-41Department: NIH department code

      Mechanism of cytokinesis in fission yeast
      $441,949

      award amount

11. Graveley, Brenton R.

    Leads 1 award · $862,998

    • 5R01HG009622-02Department: NIH department code

      Monitoring Variation in Mixtures of Long RNAs with End-to-End RT Sequencing
      $862,998

      award amount

12. Horsley, Valerie

    Leads 2 awards · $836,246

    • 2R56AR060295-07A1Department: NIH department code

      Extrinsic Regulation that Regulate Skin Homeostasis
      $480,863

      award amount
    • 5R01AR069550-03Department: NIH department code

      Mechanisms that Regulate Skin Wound Healing
      $355,383

      award amount

13. Howard, Jonathon

    Leads 1 award · $832,498

    • 5DP1MH110065-04Department: NIH department code

      Cell Biological Limitations Constrain Dendritic Branching Morphology and Neuronal Function
      $832,498

      award amount

14. Neugebauer, Karla M

    Leads 2 awards · $668,480

    • 5R01GM112766-04Department: NIH department code

      Cross-regulation between transcription and pre-mRNA splicing
      $417,230

      award amount
    • 1R21HD094013-01A1Department: NIH department code

      The dynamic energy budget of vertebrate embryogenesis
      $251,250

      award amount

15. Schlieker, Christian Dirk

    Leads 2 awards · $643,113

    • 1R01GM126835-01A1Department: NIH department code

      Defining the nuclear envelope-resident protein turnover machinery implicated in diseases affecting cholesterol metabolism
      $323,130

      award amount
    • 5R01GM114401-03Department: NIH department code

      Structure-function analysis of Torsin ATPases in the context of the membrane
      $319,983

      award amount

16. Xiong, Yong

    Leads 2 awards · $634,767

    • 5R01AI116313-04Department: NIH department code

      Recognition of Viral DNA by APOBEC3 Proteins and their Antagonization by HIV Vif
      $414,753

      award amount
    • 1R21AI136737-01Department: NIH department code

      Comparative structure and function analyses of human and mouse SAMHD1 proteins
      $220,014

      award amount

17. Lindenbach, Brett D.

    Leads 1 award · $596,514

    • 5R01AI131518-02Department: NIH department code

      Hepatitis C virus genome structure: dynamic roles in replication and infectivity
      $596,514

      award amount

18. Lam, Tukiet T

    Leads 1 award · $572,240

    • 1S10OD023651-01A1Department: NIH department code

      High Resolution Tandem Mass Spectrometer to Meet Growing Demand for Proteomics at Yale
      $572,240

      award amount

19. Greer, Charles A

    Leads 1 award · $571,391

    • 5T32NS041228-18Department: NIH department code

      Interdepartmental Neuroscience Program
      $571,391

      award amount

20. Andreev, Oleg A

    Leads 1 award · $569,403

    • 5R01GM073857-11Department: NIH department code

      Mechanism and Uses of Transmembrane Helix Insertion by Soluble Peptides
      $569,403

      award amount

21. Wei, Ning

    Leads 1 award · $523,271

    • 5R01GM047850-26Department: NIH department code

      Analysis of a light-regulated development switch
      $523,271

      award amount

22. Sung, Patrick

    Leads 3 awards · $479,865

    • 5R01ES007061-25Department: NIH department code

      DNA Repair Genes and Proteins of the RAD52 Group
      $226,875

      award amount
    • 5R01CA220123-12Department: NIH department code

      Genome Maintenance via the BRCA-PALB2 Tumor Suppressor Network
      $142,311

      award amount
    • 1R21ES029513-01Department: NIH department code

      Roles of the nucleic acid motor protein ZGRF1 in chromosome damage repair
      $110,679

      award amount

23. Koelle, Michael R

    Leads 1 award · $473,634

    • 5R01NS036918-21Department: NIH department code

      G Protein Signaling in the C.elegans Nervous System
      $473,634

      award amount

24. Loria, Joseph P

    Leads 1 award · $471,299

    • 2T32GM008283-31Department: NIH department code

      Predoctoral Program in Biophysics
      $471,299

      award amount

25. De La Cruz, Enrique M

    Leads 1 award · $426,934

    • 5R01GM097348-08Department: NIH department code

      Actin filament elasticity and actin-binding protein function
      $426,934

      award amount

26. Higley, Michael James

    Leads 1 award · $421,658

    • 1R01NS105640-01Department: NIH department code

      Impact of excitatory synapse maturation on synaptic plasticity and stability
      $421,658

      award amount

27. Gendron, Joshua Martin

    Leads 1 award · $418,750

    • 1R35GM128670-01Department: NIH department code

      Discovering protein degradation mechanisms that regulate the plant circadian clock
      $418,750

      award amount

28. Xiao, Zhuo Andrew

    Leads 1 award · $416,526

    • 5R01GM114205-04Department: NIH department code

      Investigate Novel Epigenetic Silencing Mechanisms in Mouse ESCs
      $416,526

      award amount

29. Van Wolfswinkel, Josephina C

    Leads 1 award · $411,137

    • 1R35GM128619-01Department: NIH department code

      Non-coding RNA In Stem Cell Biology
      $411,137

      award amount

30. Jacob, Yannick

    Leads 1 award · $410,063

    • 1R35GM128661-01Department: NIH department code

      Understanding the roles of histone H3 variants in promoting genomic and epigenomic stability during DNA replication and aging
      $410,063

      award amount

31. Clark, Damon Alistair

    Leads 1 award · $404,269

    • 5R01EY026555-03Department: NIH department code

      Algorithm and neural basis of a fundamental visual motion computation
      $404,269

      award amount

32. Acar, Murat

    Leads 1 award · $386,233

    • 1R01GM127870-01Department: NIH department code

      Microfluids-enabled Quantitative Systems Biology Approaches to Construct Gene Networks Regulating Yeast Lifespan and Genetic Noise Dynamics During Aging
      $386,233

      award amount

33. Koleske, Anthony J

    Leads 1 award · $382,957

    • 1R01MH115939-01Department: NIH department code

      Control of Dendritic Spine Stability via Regulation of a Stable Actin Pool
      $382,957

      award amount

34. Grutzendler, Jaime

    Leads 1 award · $374,912

    • 5R01NS089662-05Department: NIH department code

      Laminin control of CNS dendrite and dendritic spine development
      $374,912

      award amount

35. Solomon, Mark J

    Leads 1 award · $335,000

    • 1R01GM129155-01Department: NIH department code

      Regulation of the Anaphase-Promoting Complex
      $335,000

      award amount

36. Dimitrova, Nadya M

    Leads 1 award · $330,946

    • 1R37CA230580-01Department: NIH department code

      Roles and mechanisms of cis-regulatory IncRNAs in the p53 tumor suppressor pathway
      $330,946

      award amount

37. Berro, Julien

    Leads 1 award · $319,545

    • 5R01GM115636-03Department: NIH department code

      Molecular mechanisms of force production and force sensing during clathrin-mediated endocytosis
      $319,545

      award amount

38. Sindelar, Charles Vaughn

    Leads 1 award · $316,350

    • 5R01GM110530-05Department: NIH department code

      Structural basis of motility by dimeric kinesin motor proteins
      $316,350

      award amount

39. Guerrero-Medina, Giovanna

    Leads 1 award · $310,418

    • 5R25GM114000-04Department: NIH department code

      Enhancing biomedical training and diversity through a Hispanic science network
      $310,418

      award amount

40. Isaacs, Farren J.

    Leads 1 award · $304,820

    • 1R01GM125951-01Department: NIH department code

      Expanding the genetic code with phosphotyrosine and phosphothreonine
      $304,820

      award amount

41. Mochrie, Simon

    Leads 1 award · $294,945

    • 5R01GM118528-02Department: NIH department code

      Designed proteins to study and modulate cellular processes
      $294,945

      award amount

42. Kupfer, Gary M.

    Leads 1 award · $282,568

    • 5R01CA168635-06Department: NIH department code

      Mechanistic Dissection of the Falconi Anemia Pathway of DNA Damage Response and Repair
      $282,568

      award amount

43. Breslow, David King

    Leads 1 award · $243,556

    • 5R00HD082280-04Department: NIH department code

      Ciliary control of Gli protein activity in Hedgehog pathway signaling
      $243,556

      award amount

44. O'Hern, Corey

    Leads 2 awards · $232,792

    • 5T32EB019941-03Department: NIH department code

      Convergent Graduate Training in Engineering, Physics and Biology
      $184,906

      award amount
    • 3T32EB019941-03S1Department: NIH department code

      Convergent Graduate Training in Engineering, Physics and Biology
      $47,886

      award amount

45. Alexandrov, Andrei

    Leads 1 award · $209,375

    • 5R21HG009362-02Department: NIH department code

      Shotgun method for massive mutational interrogation of the entire human genome
      $209,375

      award amount

46. Keshishian, Haig S

    Leads 1 award · $209,375

    • 1R21NS109641-01Department: NIH department code

      Analysis of Synaptic Development
      $209,375

      award amount

47. Xue, Xiaoyu

    Leads 1 award · $209,375

    • 1R21ES028792-01Department: NIH department code

      Functions of the DNA/RNA motor protein AQR in R-loop resolution
      $209,375

      award amount

48. Hines, John Francis

    Leads 1 award · $122,382

    • 5R50CA211252-03Department: NIH department code

      Investigating targeted degradation of c-Met to realize more effective cancer treatment
      $122,382

      award amount

49. Pawlica, Paulina

    Leads 1 award · $90,000

    • 1K99GM129412-01Department: NIH department code

      Regulation of microRNA populations by oncogenic viruses
      $90,000

      award amount

50. Kadakia, Nirag

    Leads 1 award · $63,654

    • 1F32MH118700-01Department: NIH department code

      Quantifying the role of adaptation in olfactory coding through the logic of navigation
      $63,654

      award amount

51. Adams, Rebecca Lynn

    Leads 1 award · $61,174

    • 5F32AI126660-03Department: NIH department code

      RNA-Protein Interactions During Hepatitis C Virus Infection
      $61,174

      award amount

52. Dundon, Samantha Elizabeth Roberts

    Leads 1 award · $59,038

    • 1F32GM125193-01A1Department: NIH department code

      Elucidating the checkpoint for constriction of the cytokinetic contractile ring
      $59,038

      award amount

53. Digianantonio, Katherine

    Leads 1 award · $50,703

    • 1F32GM131426-01A1Department: NIH department code

      Probing the Mechanism By Which TRIM5 Proteins Sense HIV Capsid Assemblies
      $50,703

      award amount

54. Farley, Katherine Irene

    Leads 1 award · $38,924

    • 5F31DE026946-02Department: NIH department code

      PAX9, ribosome biogenesis, and congenital disease
      $38,924

      award amount

55. Gentile, Juliana

    Leads 1 award · $38,124

    • 1F31MH116571-01A1Department: NIH department code

      Arg and cortactin regulation of the Arp2/3 complex and its role in dendritic spine stability
      $38,124

      award amount

56. Courvan, Edward Michael Courchaine

    Leads 1 award · $29,256

    • 5F31NS105379-02Department: NIH department code

      Cajal body assembly mechanisms in vitro and in the context of neurodegenerative disease
      $29,256

      award amount

57. Rundell, Ethan

    Leads 1 award · $29,244

    • 1F31AI131531-01A1Department: NIH department code

      Using intrabodies to identify determinants of intrinsic antibiotic resistance in Pseudomonas aeruginosa
      $29,244

      award amount