Biochemistry at Yale University

Leads a grant in this department

66 contact PIs of these awards, by the funding they lead. Other principal investigators on an award are listed with it and under Co-investigators.

1. Gerstein, Mark Bender

   Leads 3 awards · $2,409,320

   • 1RF1MH123245-01A1Department: NIH department code

     Integrative analysis of genomics and imaging data from the BRAIN Initiative and other public data sources
     $1,309,909

     award amount
   • 5R01DA051906-02Department: NIH department code

     A Big Data Approach to Identify Epigenetic, Transcriptomic, and Network Dynamics as Immune Dysfunction Drivers Associated with HIV Infection and Substance Use Disorder
     $572,929

     award amount
   • 5R01HG010749-02Department: NIH department code

     Enhancing open data sharing for functional genomics experiments: Measures to quantify genomic information leakage and file formats for privacy preservation
     $526,482

     award amount

2. Nairn, Angus C.

   Leads 1 award · $1,616,094

   • 5P30DA018343-17Department: NIH department code

     Yale/NIDA Neuroproteomics Center
     $1,616,094

     award amount

3. Clark, Damon Alistair

   Leads 2 awards · $1,608,980

   • 1RF1NS121773-01Department: NIH department code

     Dissecting the roles of timing in a canonical neural computation
     $1,206,188

     award amount
   • 2R01EY026555-06Department: NIH department code

     Integrating visual counterevidence to detect self-motion in a small visual circuit
     $402,792

     award amount

4. Yan, Jing

   Leads 1 award · $1,507,500

   • 1DP2GM146253-01Department: NIH department code

     Tracking single-cell gene expression heterogeneity and its consequences in bacterial biofilms
     $1,507,500

     award amount

5. Crews, Craig M

   Leads 2 awards · $1,259,707

   • 5R35CA197589-07Department: NIH department code

     Inducing Protein Degradation: A New Pharmaceutical Paradigm
     $877,462

     award amount
   • 5R01CA238570-03Department: NIH department code

     Developing Tumor-specific PROTACs
     $382,245

     award amount

6. Holley, Scott A

   Leads 3 awards · $1,128,963

   • 5R01HD092361-05Department: NIH department code

     The cross-scale biomechanics of tissue morphogenesis
     $410,375

     award amount
   • 5R01GM127876-04Department: NIH department code

     The Molecular Biophysics and Tissue Biomechanics of Somite Morphogenesis
     $383,588

     award amount
   • 5R01GM129149-04Department: NIH department code

     EMT, Tailbud Biomechanics and Spinal Column Symmetry
     $335,000

     award amount

7. Gilbert, Wendy Victoria

   Leads 4 awards · $1,111,373

   • 5R01GM101316-07Department: NIH department code

     Functions of mRNA Pseudouridylation
     $335,000

     award amount
   • 5R01GM132358-03Department: NIH department code

     Translational Control by 5'-untranslated regions
     $331,220

     award amount
   • 5R21ES031525-02Department: NIH department code

     Functional alterations of the dihydrouridine landscape in response to environmental stress
     $250,292

     award amount
   • 5R21CA246118-02Department: NIH department code

     Cancer-associated alterations of the dihydrouridine landscape in kidney cancer
     $194,861

     award amount

8. Breaker, Ronald R

   Leads 1 award · $1,090,845

   • 5R01AI136794-04Department: NIH department code

     Exploiting Riboswitch Sensors to Reveal Antibiotics Uptake and Retention in Gram Negative Bacteria
     $1,090,845

     award amount

9. Carlson, John R

   Leads 3 awards · $1,063,176

   • 5R01DC011697-18Department: NIH department code

     Analysis of a large family of taste receptors
     $354,565

     award amount
   • 2R01DC004729-21Department: NIH department code

     Analysis of Chemosensory Receptor Genes
     $354,341

     award amount
   • 5R01DC002174-34Department: NIH department code

     Genetic and Molecular Analysis of Olfaction
     $354,270

     award amount

10. Neugebauer, Karla M

    Leads 3 awards · $1,054,993

    • 5R01GM112766-07Department: NIH department code

      Cross-regulation between transcription and pre-mRNA splicing
      $434,691

      award amount
    • 1R01GM140735-01Department: NIH department code

      Biogenesis and function of a novel class of stress-induced long non-coding RNAs
      $411,894

      award amount
    • 5R21HL150642-02Department: NIH department code

      Analysis of transcription and splicing coordination during erythropoeisis using single molecule RNA-seq
      $208,408

      award amount

11. Soll, Dieter

    Leads 1 award · $1,033,951

    • 5R35GM122560-05Department: NIH department code

      Studies of Transfer RNA
      $1,033,951

      award amount

12. Graveley, Brenton R.

    Leads 1 award · $1,005,089

    • 1R01HG011868-01Department: NIH department code

      High-throughput detection of transcriptomic and epitranscriptomic variation and kinetics using MarathonRT
      $1,005,089

      award amount

13. Xiong, Yong

    Leads 2 awards · $990,129

    • 2R37AI116313-06Department: NIH department code

      Multifaceted interactions between lentiviral Vif and host molecules for viral infectivity enhancement
      $502,500

      award amount
    • 5T32GM008283-34Department: NIH department code

      Predoctoral Program in Biophysics
      $487,629

      award amount

14. Horsley, Valerie

    Leads 3 awards · $947,429

    • 1R01AR079232-01Department: NIH department code

      Defining the role of lymphatic vessels in wound healing
      $515,898

      award amount
    • 5R01AR075412-03Department: NIH department code

      Adipocyte lipolysis regulates skin repair
      $426,236

      award amount
    • 3R01AR075412-03S1Department: NIH department code

      Adipocyte lipolysis regulates skin repair
      $5,295

      award amount

15. Hochstrasser, Mark W

    Leads 1 award · $933,136

    • 5R35GM136325-02Department: NIH department code

      Mechanisms of Cell Regulation and Manipulation by the Ubiquitin System
      $933,136

      award amount

16. Isaacs, Farren J.

    Leads 2 awards · $893,467

    • 5R01GM140481-02Department: NIH department code

      Developing next-generation genomically recoded organisms to synthetically activate biomarkers for drug discovery
      $583,364

      award amount
    • 5R01GM125951-04Department: NIH department code

      Expanding the genetic code with phosphotyrosine and phosphothreonine
      $310,103

      award amount

17. De La Cruz, Enrique M

    Leads 2 awards · $824,134

    • 5R35GM136656-02Department: NIH department code

      Actin filament mechanics and branched network turnover
      $574,170

      award amount
    • 3R35GM136656-02S1Department: NIH department code

      Actin filament mechanics and branched network turnover
      $249,964

      award amount

18. Howard, Jonathon

    Leads 2 awards · $741,533

    • 1R01NS118884-01A1Department: NIH department code

      Dendrite structure: Data-Driven Models to Bridge from Molecules to Morphology
      $418,750

      award amount
    • 5R01GM139337-02Department: NIH department code

      Microtubule Severing and Regrowth by Spastin
      $322,783

      award amount

19. Cardin, Jessica A

    Leads 1 award · $716,215

    • 1R56MH122449-01A1Department: NIH department code

      The role of TRIO signaling in neuronal development, synaptic function, and circuit connectivity
      $716,215

      award amount

20. Emonet, Thierry

    Leads 2 awards · $678,050

    • 5R01GM106189-08Department: NIH department code

      The contribution of phenotypic diversity and temporal variability to population signal transduction
      $343,050

      award amount
    • 5R01GM138533-02Department: NIH department code

      Spontaneous Organization of Phenotypes during Collective Migration
      $335,000

      award amount

21. Lin, Chenxiang

    Leads 1 award · $669,995

    • 1R01AI162260-01A1Department: NIH department code

      A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid
      $669,995

      award amount

22. Baserga, Susan J

    Leads 1 award · $630,652

    • 5R35GM131687-03Department: NIH department code

      Novel regulatory networks driving human ribosome biogenesis
      $630,652

      award amount

23. Andreev, Oleg A

    Leads 1 award · $579,262

    • 5R01GM073857-14Department: NIH department code

      Mechanism and Uses of Transmembrane Helix Insertion by Soluble Peptides
      $579,262

      award amount

24. Hatzios, Stavroula

    Leads 2 awards · $524,096

    • 5R35GM137952-02Department: NIH department code

      Understanding redox-regulated mechanisms of environmental adaptation in gastrointestinal symbionts
      $496,772

      award amount
    • 3R35GM137952-01S1Department: NIH department code

      Understanding redox-regulated mechanisms of environmental adaptation in gastrointestinal symbionts
      $27,324

      award amount

25. Higley, Michael James

    Leads 2 awards · $518,918

    • 5R01NS105640-04Department: NIH department code

      Impact of excitatory synapse maturation on synaptic plasticity and stability
      $477,112

      award amount
    • 3R01NS105640-04S1Department: NIH department code

      Impact of excitatory synapse maturation on synaptic plasticity and stability
      $41,806

      award amount

26. Collins, Kevin Michael

    Leads 2 awards · $507,506

    • 5R01NS086932-07Department: NIH department code

      Neuromodulator signaling and activity in the C. elegans egg-laying circuit
      $443,664

      award amount
    • 3R01NS086932-07S1Department: NIH department code

      Neuromodulator signaling and activity in the C. elegans egg-laying circuit
      $63,842

      award amount

27. Koleske, Anthony J

    Leads 2 awards · $478,737

    • 5R01MH115939-04Department: NIH department code

      Control of Dendritic Spine Stability via Regulation of a Stable Actin Pool
      $393,679

      award amount
    • 3R01MH115939-04S1Department: NIH department code

      Control of Dendritic Spine Stability via Regulation of a Stable Actin Pool
      $85,058

      award amount

28. Atit, Radhika P

    Leads 1 award · $476,434

    • 5R01AR076938-02Department: NIH department code

      Mechanism and Impact of Dermal adipocyte remodeling in skin fibrosis
      $476,434

      award amount

29. Forscher, Paul

    Leads 1 award · $418,750

    • 2R01NS028695-28A1Department: NIH department code

      Mechanical catalysis of calcineurin dependent cofilin activity during chemotropic axon growth: a new role for PKC in coordinating actin dynamics and myosin II contractility
      $418,750

      award amount

30. Gendron, Joshua Martin

    Leads 1 award · $418,750

    • 5R35GM128670-04Department: NIH department code

      Discovering protein degradation mechanisms that regulate the plant circadian clock
      $418,750

      award amount

31. Paulsen, Candice Elaine

    Leads 1 award · $418,750

    • 1R35GM142825-01Department: NIH department code

      Molecular mechanisms of TRPA1 regulation
      $418,750

      award amount

32. Jacob, Yannick

    Leads 1 award · $418,557

    • 5R35GM128661-04Department: NIH department code

      Understanding the roles of histone H3 variants in promoting genomic and epigenomic stability during DNA replication and aging
      $418,557

      award amount

33. Van Wolfswinkel, Josephina C

    Leads 1 award · $413,335

    • 5R35GM128619-04Department: NIH department code

      Non-coding RNA In Stem Cell Biology
      $413,335

      award amount

34. Breslow, David King

    Leads 1 award · $412,000

    • 5R35GM137956-02Department: NIH department code

      Mechanisms of Primary Cilium Assembly and Disassembly
      $412,000

      award amount

35. Zhang, Kai Jack

    Leads 1 award · $410,650

    • 1R35GM142959-01Department: NIH department code

      Structural basis of dynein-driven ciliary motility
      $410,650

      award amount

36. Strobel, Scott A

    Leads 1 award · $402,196

    • 5R01GM136969-02Department: NIH department code

      Discovery and Characterization of New Riboswitches
      $402,196

      award amount

37. Simon, Matthew David

    Leads 1 award · $360,908

    • 5R01GM137117-02Department: NIH department code

      Revealing the dynamics of RNA metabolism with nucleotide recoding chemistry
      $360,908

      award amount

38. Dimitrova, Nadya M

    Leads 1 award · $359,545

    • 5R37CA230580-04Department: NIH department code

      Roles and mechanisms of cis-regulatory IncRNAs in the p53 tumor suppressor pathway
      $359,545

      award amount

39. Bleichert, Franziska

    Leads 1 award · $351,750

    • 1R01GM141313-01Department: NIH department code

      Mechanisms for recruitment and function of metazoan replication initiation factors
      $351,750

      award amount

40. Sindelar, Charles Vaughn

    Leads 1 award · $343,859

    • 5R01GM110530-07Department: NIH department code

      Structural basis of motility by dimeric kinesin and myosin motor proteins
      $343,859

      award amount

41. Xu, Jinrui

    Leads 1 award · $335,000

    • 1R03OD032623-01Department: NIH department code

      Using three-dimensional genome structure to refine eQTL detection
      $335,000

      award amount

42. Berro, Julien

    Leads 1 award · $332,659

    • 2R01GM115636-06A1Department: NIH department code

      Molecular mechanisms of force production and force sensing during clathrin-mediated endocytosis
      $332,659

      award amount

43. Bahmanyar, Shirin

    Leads 1 award · $323,214

    • 5R01GM131004-03Department: NIH department code

      Defining the role of bilayer lipid composition in nuclear envelope dynamics and genome protection
      $323,214

      award amount

44. Schlieker, Christian Dirk

    Leads 1 award · $309,370

    • 5R01GM126835-04Department: NIH department code

      Defining the nuclear envelope-resident protein turnover machinery implicated in diseases affecting cholesterol metabolism
      $309,370

      award amount

45. Pollard, Thomas D.

    Leads 1 award · $226,524

    • 3R01GM026132-43S1Department: NIH department code

      Mechanism of cytokinesis in fission yeast
      $226,524

      award amount

46. Musier-Forsyth, Karin M

    Leads 1 award · $217,898

    • 1R21AI157890-01A1Department: NIH department code

      Mechanism of selective packaging of primer tRNALys3 by HIV-1
      $217,898

      award amount

47. Kadakia, Nirag

    Leads 2 awards · $194,187

    • 1K99DC019397-01Department: NIH department code

      Detecting the motion of odors: Olfactory direction sensing in Drosophila
      $120,625

      award amount
    • 5F32MH118700-03Department: NIH department code

      Quantifying the role of adaptation in olfactory coding through the logic of navigation
      $73,562

      award amount

48. Kabeche, Lilian Carolina

    Leads 1 award · $186,192

    • 5K22CA244865-02Department: NIH department code

      Defining the DNA damage pathway in faithful mitotic progression
      $186,192

      award amount

49. Tharp, Jeffery Micheal

    Leads 1 award · $95,215

    • 1K99GM141320-01Department: NIH department code

      Genetically encoded bicyclic peptide libraries for the discoveryof novel antiviral agents
      $95,215

      award amount

50. Niederer, Rachel O.

    Leads 1 award · $93,905

    • 5K99GM135533-02Department: NIH department code

      Translational control by 5'-UTR elements
      $93,905

      award amount

51. Ebrahim, Shimaa Abdelsalam Mohamed

    Leads 1 award · $72,630

    • 5F32DC018445-02Department: NIH department code

      Molecular basis of olfaction in Tsetse fly
      $72,630

      award amount

52. Genuth, Miriam

    Leads 1 award · $68,562

    • 5F32GM137502-02Department: NIH department code

      Order to Disorder Transition in Zebrafish Tailbud Cell Migration
      $68,562

      award amount

53. Grome, Michael William

    Leads 1 award · $66,390

    • 1F32GM142204-01Department: NIH department code

      Programmable Keratinous Bio-adhesives for Recalcitrant Wound Recovery
      $66,390

      award amount

54. Martinez, Nicole

    Leads 1 award · $48,385

    • 5K99GM135537-02Department: NIH department code

      Role of pseudouridines in pre-mRNA processing
      $48,385

      award amount

55. Corcoran, Ellen Elizabeth

    Leads 1 award · $46,036

    • 1F31MH127891-01Department: NIH department code

      Disruption of TRIO signaling through PDE4A5 in neurodevelopmental disorders
      $46,036

      award amount

56. Draycott, Austin Stratton

    Leads 1 award · $46,036

    • 5F31CA254339-02Department: NIH department code

      Developing Tools to Map and Quantify Dihydrouridine in the Mammalian Transcriptome
      $46,036

      award amount

57. Moore, Jeremy Philippe

    Leads 1 award · $46,036

    • 1F31AI164817-01Department: NIH department code

      Cell-to-Cell Variability in Chemotactic Signal Integration
      $46,036

      award amount

58. Wasko, Renee

    Leads 1 award · $46,036

    • 5F31AR073094-03Department: NIH department code

      Dissecting the contributions of Langerhans cell to cutaneous wound healing
      $46,036

      award amount

59. Arthur, Ashley L

    Leads 1 award · $41,930

    • 5F32GM139389-02Department: NIH department code

      Examining cell polarity in nerve nets
      $41,930

      award amount

60. McCool, Mason

    Leads 1 award · $31,695

    • 5F31DE030332-02Department: NIH department code

      CRK regulation of ribosome biogenesis and craniofacial development
      $31,695

      award amount

61. Lewis, Cole

    Leads 1 award · $30,917

    • 1F31DK129022-01A1Department: NIH department code

      Functional Characterization of the Pseudouridine Synthase PUS10
      $30,917

      award amount

62. Christie, Nakeirah Tashiara Mathews

    Leads 1 award · $30,896

    • 5F31NS115315-02Department: NIH department code

      The role of a previously undiscovered sensory cilium in the model neural circuit that controls C. elegans egg laying
      $30,896

      award amount

63. Butt, Allison Marie

    Leads 1 award · $30,895

    • 5F31NS118810-02Department: NIH department code

      Function of the neuropeptide NLP-3 in relationship to serotonin signaling within C. elegans egg-laying circuit
      $30,895

      award amount

64. Bircher, Josie

    Leads 1 award · $21,530

    • 5F31NS113511-03Department: NIH department code

      Regulation of the actin cytoskeleton by Abl2 and its role in dendritic spine stability
      $21,530

      award amount

65. Carrocci, Tucker Joe

    Leads 1 award · $17,141

    • 3F32GM134572-01A1S1Department: NIH department code

      Molecular Mechanisms Coupling Transcription and Splicing
      $17,141

      award amount

66. Gursoy, Gamze

    Leads 1 award · $13,670

    • 5K99HG010909-02Department: NIH department code

      Realistic quantification of potential privacy loss from genomic summary results
      $13,670

      award amount