Scheme 1 from: Demchenko SА, Fedchenkova YА, Yeromina HО, Herashenko IV, Berdnyk OH, Demchenko AM (2021) The synthesis of N-(4-aryl-thiazol-2-yl)-N1-(4,5,6,7-tetrahydro-3H-azepin-2-yl)-hydrazine hydrobromides and the cardioprotective activity of (41-methoxyphenyl-thiazol-2-yl) derivative. Pharmacia 68(1): 141-146. https://doi.org/10.3897/pharmacia.68.e58788

Scheme 1 Synthesis of N-(4-aryl-thiazol-2-yl)-N1-(4,5,6,7-tetrahydro-3Н-azepin-2-yl)-hydrazine hydrobromides (5 a–d). Where: 1, 3, 5: a) R=R1=H b) R=OCH3, R1=H; c) R=Cl, R1=H; d) RR1=-OCH2CH2O-.