Cell-free DNA Fragmentomics and Second Malignant Neoplasm Risk in Patients with PTEN Hamartoma Tumor Syndrome

<p><strong>Supplementary dataset for manuscript:</strong></p> <p><strong>Cell-free DNA Fragmentomics and Second Malignant Neoplasm Risk in Patients with PTEN Hamartoma Tumor Syndrome</strong></p> <p>Affiliations:</p> <p>¹Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA</p> <p>²Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA</p> <p>³Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH 44195, USA</p> <p>⁴Center for Personalized Genetic Healthcare, Medical Specialties Institute, Cleveland Clinic, Cleveland, OH 44195, USA</p> <p>⁵Center for Immunotherapy and Precision Immuno-oncology, Cleveland Clinic, Cleveland, OH 44195, USA</p> <p>⁶Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA</p> <p>⁷Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA</p> <p>⁸Germline High Risk Cancer Focus Group, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA</p> <p><strong><em>Correspondence</em></strong>:</p> <p>Darren Liu, MD, MS (<a href="https://orcid.org/0000-0002-6703-1843">https://orcid.org/0000-0002-3693-5145)</a></p> <p>Cleveland Clinic Genomic Medicine Institute</p> <p>9500 Euclid Avenue, Cleveland, OH 44195, USA</p> <p>E-mail: liud5@ccf.org&nbsp;</p>