An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection: Dataset

<p>Supplementary files (data and analysis) for "An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection"</p> <p>Supplementary File 1: C3H_pheno_fix_Jun7_2023_nolowmut.csv</p> <p>Data for all mice in MA experiment including: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID</p> <p>&nbsp;</p> <p>Supplementary File 2: C3H_pheno_Kontrol_June2023.csv</p> <p>Data for all control mice including: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID</p> <p>&nbsp;</p> <p>Supplementary File 3: C3H_birthdates.csv</p> <p>Data for all C3H mice including: mouse ID, birthdate</p> <p>&nbsp;</p> <p>Supplementary File 4: MA_pheno.R</p> <p>R code for visualising trait data, running linear regressions, and comparing control and MA experiment data</p> <p>&nbsp;</p> <p>Supplementary File 5: C3H_pheno_burnin20_Jun7_2023_nolowmut.csv</p> <p>Data for all mice in MA experiment including a 20 generation burn-in to simulate mutation-drift balance for Animal model analyses: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID</p> <p>&nbsp;</p> <p>Supplementary File 6: asreml_C3H_ALL.R</p> <p>R code for estimating mutational heritabilities using mixed model analysis</p> <p>&nbsp;</p> <p>Supplementary File 7: C3H_ped_rekey_Jun2023.csv</p> <p>Pedigree data for all mice in MA experiment</p> <p>&nbsp;</p> <p>Supplementary File 8: C3H_ped_rekey_KEY.csv</p> <p>Key for pedigree data file</p> <p>&nbsp;</p> <p>Supplementary File 9: plot_pedigree_tree_MS_final.R</p> <p>R code for visualising pedigree of mice in MA experiment</p>