Figure 9 from: Mingorance Gámez C (2018) Epigenetic function of Granulocytic nuclei? Designing a new line of research. Research Ideas and Outcomes 4: e29438. https://doi.org/10.3897/rio.4.e29438

Figure 9 Distribution between lobes can help both copies of the unused sequence to be modified to become NETs (A), but it can also help to modify only one copy of a used gene (B) by containing the modifying enzymes in one lobe and keeping a functional copy of the gene for normal transcription.