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Fig. 24 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 24. Reaction catalyzed by COQ6 in ubiquinone biosynthesis. The FAD-dependent hydroxylation occurs in the 5-position of the aromatic ring as indicated (highlighted in red). COQ6 belongs to the class A FPMOs and depends on NAD(P)H as reductant. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Fig. 29 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 29. Reaction catalyzed by carotene cis-trans isomerase. The reaction shown requires reduced FAD for the redox-neutral cis-to-trans isomerization at position 9 and 9′ of prolycopene and generates the linear all-trans-lycopene. The reduced FAD is probably generated at the expense of NAD(P)H. Thus, the enzyme appears to possess a second activity that enables the transfer of a hydride from the reduced nicotinamide to the bound FAD cofactor.

opencc-by-4.0Aug 2023View details →

Structure Dependence of CO2 Reduction Electrocatalyzed by Metal-Nanographene Complexes: A Computational Study

Data files related to the manuscript titled 'Structure Dependence of CO2 Reduction Electrocatalyzed by Metal-Nanographene Complexes: A Computational Study,' in  'Journal of Physical Chemistry A'

opencc-by-4.0Aug 2023View details →

Pressure effects on frequency dependent wave velocities of saturated rocks

These data are the P- and S-wave velocities obtained by Ba et al. through ultrasonic experimental measurements and the seismic measurements on a rock sample at different pressures. In the package of data, wave velocities measured at different pore fluids and frequencies are saved as different XLSX files. The title of each XLSX file includes the sample number, saturation condition and measurement frequency. For instance, "Sample D_Seismic_Brine" denotes that wave velocities of sample D measured with the full brine saturation are measured at seismic frequency, while "Sample D_Ultrasonic_Gas" denotes that wave velocities of gas-saturated sample D are measured at ultrasonic frequency. The package also includes the TXT file of sample properties. In the TXT files of seismic measurements, the first column gives the differential pressure values, the second column gives frequency values, the third and fourth column gives P- and S-wave velocities. In the TXT files of ultrasonic measurements, the first column gives the differential pressure values, the second and third column gives P- and S-wave velocities.

Fig. 47 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 47. Reaction catalyzed by D-amino acid oxidase. Regeneration of the reduced FAD occurs by dioxygen leading to the production of hydrogen peroxide (top). Note that the direct product of the oxidation, the corresponding imino acid, is non-enzymatically hydrolyzed to yield the α-keto acid and ammonia.

Fig. 33 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 33. Reaction of flavin-dependent monooxygenases involved in auxin biosynthesis. All enzymes forming clade 2 were shown to play an important role in auxin biosynthesis, as they were identified to mediate the conversion of indole-3-pyruvic acid to indole-3-acetic acid (Dai et al., 2013; Mashiguchi et al., 2011).

Fig. 28 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 28. Reaction of phytoene dehydrogenase/desaturase. The enzyme introduces two double bonds at position 11 and 11′ and mediates the concomitant trans-to-cis isomerization at position 9 and 9'. Reoxidation of the reduced cofactor is achieved by electron transfer to plastoquinone in the plastid membrane.

Fig. 7 in The scope of flavin-dependent reactions and processes in the model plant Arabidopsis thaliana

Fig. 7. Reactions catalyzed by isovaleryl-CoA dehydrogenase in valine and isoleucine degradation. Reoxidation of reduced FAD occurs by electron donation to ETF, which in turn feeds the electrons into the mETC via ETF-QO.

opencc-by-4.0Aug 2023View details →

Elevation data for On the More Complex Wavelength Dependency of Airy Isostasy in Icy Shells of Ocean Worlds

Elevations for surface and root topographies of simulated displacements.

Fig. 2. A in The antioxidant system in Olea europaea to enhanced UV-B radiation also depends on flavonoids and secoiridoids

Fig. 2. A - Variation in reduced (AsA) and oxidized ascorbate (DHA), B - AsA redox state (AsA/DHA), C - reduced (GSH) and oxidized glutathione (GSSG), and D - and glutathione redox potential (GSH/GSSG) in leaves of O. europaea plants under control conditions and exposed to UV-B treatments (UV–B1 and UV-B2). Values are mean ± s.d. (n = 6–8). For each parameter, different letters indicate statistical differences between treatments (P <0.05) base on Holms Sidak Comparison Test.

Fig. 2 in The antioxidant system in Olea europaea to enhanced UV-B radiation also depends on flavonoids and secoiridoids

Fig. 2 presents the changes of AsA, DHA, GSH and GSSG, AsA/DHA and GSH/GSSG in O. europaea leaves after UV-B exposure. Compared with controls, plants exposed to UV-B1 had decreased levels of both AsA and DHA, which led to a maintenance of the AsA/DHA ratio (P> 0.05, Fig. 2A and B). Contrarily, GSH levels decreased while the GSSG increased significantly, decreasing the GSH/GSSG ratio (P <0.05, Fig. 2C and D). Plants exposed to UV-B2 showed an increase of DHA and, mostly, of AsA pools, which led to an increase of the AsA/DHA ratio (P <0.05, Fig. 2A and B). On other hand GSH levels also increased but GSSG was not influenced, which supported the increase of GSH/GSSG (P <0.05, Fig. 2C and D).

Fig. 3. A in The antioxidant system in Olea europaea to enhanced UV-B radiation also depends on flavonoids and secoiridoids

Fig. 3. A - secoiridoids, B - flavonoids, and C - hydroxycinnamic acid derivatives in leaves of O. europaea plants under control conditions and exposed to UV-B treatments (UV–B1 and UV-B2). Values are mean ± s.d. (n = 3). For each compound, different letters indicate statistical differences between treatments (P <0.05) base on Holms Sidak Comparison Test.

Fig. 4 in The antioxidant system in Olea europaea to enhanced UV-B radiation also depends on flavonoids and secoiridoids

Fig. 4. General overview of the metabolites and antioxidant enzymes changes in O. europaea plants under UV-B doses: moderate (UV–B1) and high (UV–B2). Relative levels [expressed as log2 (UV–B/control)] are given besides (two colored rectangles) each identified metabolite/compound or enzyme activity as a heat-map, and the upper colored rectangle refers to UV-B1 treatment while the lower one refer to the UV-B2 treatment. Protective responses in O. europaea involve the activation of both enzymatic and non-enzymatic antioxidant mechanisms to control ROS (namely H2O2) homeostasis, but the enzymatic and AsA/GSH pools are more required by higher UV doses, while polyphenols pathways are similarly solicited by both treatments. UV-B1 treatment increases SOD, CAT and GPox activities and GSSG content, reducing Gr and APX activities and the contents of AsA, DHA and GSH. UV-B2 treatment, besides SOD, CAT and GPox activation, also increases Gr activity and the contents of AsA, DHA and GSH. Flavonoids (4ʹ or 3ʹ-methoxy luteolin glucoside and 4ʹ-methoxy luteolin decrease), secoiridoids (oleuropein decrease and 2ʹʹ- methoxyoleuropein increase) and HCAds (β-hydroxyverbascoside increase) respond similarly to both UV-B doses, putatively acting as UV-B shields and/or ROS scavengers.

opennotspecifiedAug 2020View details →

Fig. 5. Compound 7 induced apoptosis through a mitochondria-dependent pathway. A in Bufadienolide glycosides and bufadienolides from the whole plants of Helleborus lividus, and their cytotoxic activity

Fig. 5. Compound 7 induced apoptosis through a mitochondria-dependent pathway. A, Mitochondrial membrane morphology of HL- 60 cells treated with 7. HL-60 cells were stained with MitoCapture™ reagent after treatment with either 0.21 μM of 7 or 33 μM of cisplatin for 6 h and observed under a fluorescence microscope. B, Release of cytochrome c from mitochondria of HL-60 cells treated with 7. HL-60 cells were treated with either 0.21 μM of 7 or 33 μM of cisplatin for 8 h, and the release of cytochrome c into the cytoplasm was evaluated by Western blot analysis.

opennotspecifiedApr 2020View details →

Fig. 5. Compound 2 induced apoptosis through a mitochondria-dependent pathway. A in Bufadienolides from the whole plants of Helleborus foetidus and their cytotoxicity

Fig. 5. Compound 2 induced apoptosis through a mitochondria-dependent pathway. A, Mitochondrial membrane morphology of HL-60 cells treated with 2. HL-60 cells were stained with MitoCapture™ reagent after treatment with either 0.5 μM of 2 or 33 μM of cisplatin for 10 h and observed under a fluorescence microscope. B, Release of cytochrome c from mitochondria of HL-60 cells treated with 2. HL-60 cells were treated with either 0.5 μM of 2 or 33 μM of cisplatin for 6 h, and the release of cytochrome c into the cytoplasm was evaluated by Western blot analysis.

opennotspecifiedNov 2020View details →

Fig. 6. ABDCM dose-dependently inhibited TMEM16A in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Fig. 6. ABDCM dose-dependently inhibited TMEM16A in Calu-3 cells. (A) Representative trace of change in Cl current. ABDCM at indicated concentration were applied 20 min prior to TMEM16A activation by Eact (10 μM). (B) Dose-response relationship of TMEM16A inhibition by ABDCM. Data were fitted to the Hill equation and expressed as means of Eact-induced Cl current (mean ± S.E.M, n = 3).

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Data from: Phase-dependent differential in vitro and ex vivo susceptibility of Aspergillus flavus and Fusarium keratoplasticum to azole antifungals

Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with Aspergillus and Fusarium species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success. Though clinical infections are typically characterized by a dense network of mature mycelium, traditional models used to test antifungal susceptibility of FK isolates exclusively evaluate susceptibility in fungal cultures derived from asexual spores known as conidia. The purpose of this study was to characterize differences in fungal response when topical antifungal treatment is initiated at progressive phases of fungal development. We compared efficacy of voriconazole and luliconazole against in vitro cultures of A. flavus and F. keratoplasticum at 0, 24, and 48 h of fungal development. Data from this assay is included here, reported as end-point absorbance values. A porcine cadaver corneal model was used to compare antifungal efficacy of voriconazole and luliconazole in ex vivo tissue cultures of A. flavus and F. keratoplasticum at 0, 24, and 48 h of fungal development. Data from this assay may be found here, reported as pixel counts of the determined area.

opencc-zeroAug 2023View details →

opencc-by-4.0Sep 2023View details →

Preliminary characterization of submarine basalt magnetic mineralogy using amplitude-dependence of magnetic susceptibility

Experimental dataset for Yang et al., "Preliminary characterization of submarine basalt magnetic mineralogy using amplitude-dependence of magnetic susceptibility", submitted to G-cubed. Data includes amplitude dependence of magnetic susceptibility, hysteresis loop, FORC, x-T thermomagnetic and AF/thermal demagnetization.

opennotspecifiedJun 2022View details →

Fig. 4 in Assessing the Old-Growth Dependency of Two Saproxylic Beetle Species in the Southern Appalachian Mountains

Fig. 4. Boxplots of (A) elevatioc, (B) tree diameter, acd (C) basal area amocg sampled historic distkrbacce classes ic Great Smoky Mokctaics Natiocal Park.