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zenodo12/100

Dataset related to article "Predictive factors for progression of patients with carcinoma in situ of the bladder at long-term follow-up: pure versus non-pure CIS."

<p>BACKGROUND:</p> <p>The aim of this study was to identify the predictive factors for progression defined as any event that shifted the management of the disease from a bladder sparing approach, by comparing patients with pure versus non-pure carcinoma in situ (CIS) of the bladder.</p> <p>METHODS:</p> <p>A retrospective analysis was carried out in consecutive patients affected by newly-diagnosed pure CIS and non-pure CIS (excluding cases with concomitant muscle invasive cancer). All patients were enrolled a in our institution from 1998 to 2010. Data was prospectively collected. Main end point was progression-free survival.</p> <p>RESULTS:</p> <p>Overall, 149 patients with CIS were identified for the analysis. A total of 98 patients had pure CIS (66%). Median follow-up was 103 months (range: 40-206 months). Progression occurred in 29 patients (19%). A total of 30 patients died during the follow-up (20%). In 13 cases (9%), the death was cancer specific. Progression-free survival estimate was 181 months (95% CI: 169-193 months) and 154 months (95% CI: 133-176 months) respectively for pure and non-pure CIS population (P=0.03). Among examined variables (age, gender, symptoms, smoking habit, ASA score, number of bacillus Calmette-Gu&eacute;rin [BCG] instillations), multivariate analysis disclosed that only CIS type was an independent predictor of progression (P=0.03) with a relative risk of 0.37 in favor of pure CIS.</p> <p>CONCLUSIONS:</p> <p>Pure and non-pure CIS are efficiently treated by BCG therapy combined with trans-urethral resection and/or radical cystectomy, with relatively low rate of progression. CIS type was the only significant predictor of progression.</p>

restrictedMar 2020View details →
zenodo12/100

Dataset related to the article "An Ablation Index Operator-Independent Approach to Improve Efficacy in Atrial Fibrillation Ablation at 24-month Follow-Up: A Single Center Experience"

<p>This record contains raw data related to the article &quot;An Ablation Index Operator-Independent Approach to Improve Efficacy in Atrial Fibrillation Ablation at 24-month Follow-Up: A Single Center Experience&quot;</p> <p>ABSTRACT</p> <p><strong>Purpose:&nbsp;</strong>Since the introduction of catheter ablation as a mainstream treatment for atrial fibrillation (AF), several technical improvements have been put forward. In this contest, Ablation Index (AI) is an accurate ablation quality marker by incorporating power, delivery time, contact force (CF), and catheter stability in a weighted formula. The aim of our study is to evaluate the efficacy of AI-guided AF ablation over 24 month follow-up.</p> <p><strong>Methods:&nbsp;</strong>We evaluated 72 consecutive patients with drug-refractory paroxysmal (66.7%) and early-persistent AF (33.3%) undergoing AI-guided ablation, compared to 72 propensity-matched control patients who underwent CF-guided procedure. All procedures were performed by three skilled operators. Data concerning procedural characteristics and long-term freedom from AF recurrence were analyzed.</p> <p><strong>Results:&nbsp;</strong>At 24-month follow-up, Kaplan-Meier curves of AF recurrence were significantly lower in AI group than in CF group (15.5% vs. 30.6%; p 0.042). These findings were confirmed in a sub analysis regardless of the continued use of antiarrhythmic drugs in the follow-up (42.2% in AI-guided group and 66.7% in CF-guided group, p 0.004). At 24-month follow-up, a positive trend in the decrease of arrhythmia recurrences was observed in AI-guided ablation for all operators.</p> <p><strong>Conclusions:&nbsp;</strong>AI-guided ablation results more effective than CF-guided ablation as demonstrated by a lower incidence of AF recurrences regardless of the use of antiarrhythmic drugs in the follow-up. Each operator seems to improve the long-term success using an AI-guided ablation, thus showing both the efficacy and the reproducibility of this approach.</p> <p>&nbsp;</p>

restrictedMay 2020View details →
zenodo12/100

Loss to follow-up in a randomized controlled trial study for pediatric weight management (EPOC)

<p>This is the data set as supporting information, provided as .sav file.</p> <p>Further information is available on request.</p>

restrictedNov 2016View details →
zenodo12/100

CAARMS Follow-up adolescents

<table align="left"> <tbody> <tr> <td> <p>This database includes the raw data linked with the paper &ldquo;Prognostic Accuracy of DSM-5 Attenuated Psychosis Syndrome in Adolescents: Prospective Real-World 5-Year Cohort Study&rdquo; published on &ldquo;Schizophrenia Bulletin&rdquo;.</p> <p>In this paper, we reported sociodemographic characteristics, family history of any DSM-5 psychiatric disorder, personal history of any DSM-5 psychiatric disorder, psychopathological assessment, and level of functioning. We aimed to characterize the profile of APS adolescents compared to adolescents suffering from early onset psychosis and with other psychiatric disorders and to estimate their long-term risk of transition to psychosis.</p> <p>Participants were then divided into three groups: 1) adolescents with established Early Onset Psychosis (EOP), 2) adolescents meeting DSM-5 Attenuated psychotic Syndrome (APS) criteria and the attenuated psychotic symptoms subgroup of the Clinical High Risk for Psychosis (CHR-P), 3) adolescents with other DSM-5 psychiatric disorders who did not meet APS/EOP criteria.</p> <p>We found that help-seeking adolescents with APS show a distinctive baseline clinical profile at baseline compared to non-APS and early psychosis adolescents. Moreover, the cumulative proportion of transition to psychosis in help-seeking APS adolescents was cumulated to 26.8% at 4-year follow-up.</p> </td> </tr> </tbody> </table>

restrictedNov 2021View details →
zenodo12/100

Ten-year follow-up of cardiac function and neural regulation in a group of amateur half-marathon runners

<p>Dataset from&nbsp;De Maria B, de Oliveira Gois M, Catai AM, Marra C, Lucini D, Porta A, Pagani M, Dalla Vecchia LA. Ten-year follow-up of cardiac function and neural regulation in a group of amateur half-marathon runners. Open Heart. 2021 Feb;8(1):e001561. doi: 10.1136/openhrt-2020-001561. PMID: 33563778; PMCID: PMC7875294.</p> <p>Abstract</p> <p><strong>Objective:&nbsp;</strong>In the last years, a debate exists about type, intensity and frequency of physical exercise that is really indicated to protect healthy subjects from cardiovascular disease. Regular physical training has been associated with an improved cardiovascular risk profile, but it has also been demonstrated that strenuous and uncontrolled physical exercise could be dangerous, in terms of increased cardiovascular morbidity and mortality. In the present study, we evaluated a group of 35 amateur half-marathon runners, who were likewise studied 10 years before (B). The results of B suggested that an increased cardiac sympathetic modulation could potentially represent a negative prognostic factor. The aim of this follow-up was to assess the medium-long-term effects of moderate to vigorous physical training on the cardiovascular neural control, cardiac function and occurrence of cardiovascular diseases.</p> <p><strong>Methods:&nbsp;</strong>Each enrolled subject underwent: (1) an interview and physical examination to ascertain the presence of cardiovascular disease; (2) standing test to evaluate the cardiovascular neural control by means of heart rate variability (HRV), arterial blood pressure (AP) variability and baroreflex sensitivity (BRS); (3) transthoracic echocardiography to evaluate cardiac function.</p> <p><strong>Results:&nbsp;</strong>At 10-year follow-up (FU), in this group of middle-aged athletes the occurrence of cardiovascular diseases was low, not unlike that of the overall population. The results of HRV analysis showed a decreased sympathetic and increased vagal modulation directed to the heart, compared with B. In addition, HRV, AP variability and BRS indices showed a physiological response to active standing. Finally, athletes had normal echocardiographic measures.</p> <p><strong>Conclusion:&nbsp;</strong>We conclude that in our group of athletes a regular moderate-vigorous physical training through the 10 years was quite beneficial as the prevalence of sympathetic cardiac modulation observed at B was not accompanied by increased cardiovascular risk, on the contrary a slight prevalence of vagal indices was observed at FU.</p>

restrictedJan 2022View details →
zenodo12/100

Long-term follow-up after recanalisation of aortic arch atresia.

<p>Dataset from&nbsp;Chessa M, Favoccia C, Jha NK, Carminati M, Fernandez Gonzalez L, Eicken A, Butera G, Ferreira Martins JD, Pinto F, Tofeig M, Khan MD. Long-term follow-up after recanalisation of aortic arch atresia. EuroIntervention. 2021 Feb 5;16(15):e1274-e1280. doi: 10.4244/EIJ-D-18-00857. PMID: 31235456.</p> <p>Abstract</p> <p><strong>Aims:&nbsp;</strong>Aortic arch atresia (AAA) is one of the rarest obstructive defects. The presence of this anomaly in adult age is uncommon. The typical anatomic feature consists of a complete occlusion of the membranous obstruction resulting in an acquired atresia without flow continuity between the proximal and distal segments. This feature is important in determining the feasibility of percutaneous intervention. The aim of the present study was to share long-term follow-up data of adult patients with AAA requiring percutaneous interventions for the management of this rare anomaly involving five different centres.</p> <p><strong>Methods and results:&nbsp;</strong>Retrospective data of 19 patients (12 males, 63.2%, mean age 32.2&plusmn;18.9 years) diagnosed with AAA treated in five different centres between 1999 and 2017 were collected. All patients underwent percutaneous recanalisation by (1) radiofrequency (RF) system (five patients, 26.3%), (2) extra-stiff guidewire (12 patients, 63.2%), and (3) transseptal needle (two patients, 10.5%). All procedures were subsequently followed by covered stent implantation. Two patients developed complications during the procedure and one of them died. Over a median follow-up of 4.94 years, four (21%) patients were able to be weaned from medications for hypertension. All the patients underwent reassessment for recurrence or restenosis during the follow-up. Seven (36.8%) patients underwent successful stent dilatation with a balloon. After the intervention, one patient experienced a late complication; however, one patient died due to an unknown cause believed to be unrelated to the previous recanalisation procedure.</p> <p><strong>Conclusions:&nbsp;</strong>Percutaneous treatment of AAA is feasible with good long-term survival. This study reports the largest case series so far available in the literature.</p>

restrictedJan 2022View details →
zenodo12/100

Dataset related to article "Sport Activity and Clinical Outcomes after Hip Arthroscopy with Acetabular Microfractures at a Minimum 2-Year Follow-Up: A Matched-Pair Controlled Study".

<p>&nbsp;This record contains raw data related to article &ldquo;</p> <p>Sport Activity and Clinical Outcomes after Hip Arthroscopy with Acetabular Microfractures at a Minimum 2-Year Follow-Up: A Matched-Pair Controlled Study&quot;</p> <p>Abstract: Background: Acetabular microfractures for cartilage lesions have been shown to be a safe procedure able to improve patient reported outcomes (PROs). Nevertheless, the return to sport activity rate represents a crucial outcome to be investigated in these young athletic patients. Methods: Patients undergoing acetabular microfracture for full chondral acetabular lesions were compared to a 1:1 matched-pair by age and gender control group undergoing hip arthroscopy without microfractures. Clinical assessment was performed with PROs and participation in sports in terms of type and level of activities was evaluated preoperatively and at 2-years follow-up. Results: A total of 62 patients with an average age of 35.1 &plusmn; 8.1 (microfracture group) and 36.4 &plusmn; 6.3 (control group) were included. In both groups, the average values of PROs significantly increased from preoperatively to the last follow-up. There was no significant difference between the two groups in the number of patients playing at the amateur and elite level preoperatively and at the last follow-up. Conclusions: Microfractures for the management of full-thickness acetabular chondral defect provides good clinical results at a minimum follow-up of two years, which are not inferior to a matched-pair control group. Patients undergoing this procedure are likely able to return at the same level of sport before surgery.</p> <p>&nbsp;</p>

restrictedJul 2022View details →
zenodo12/100

Dataset on follow-up results of Tachidino treatment of dyslexia

<p>The dataset contains the scores obtained by a group of 80 Italian children with Developmental Dyslexia, treated with the remotely supervised treatment Tachidino, at pre-post (indicated by prefix A), post-test (indicated by prefix B) and follow-up after 6 months of no-treatment (indicated by prefix F). It also contains difference-scores between post tet and pre-test (indicated by the code 12), between post-test and follow-up (indicated by the code 23) and between pre-test and follow-up (indicated by the code 13).</p>

restrictedAug 2021View details →
zenodo12/100

Safe Follow-Up after Endovascular Aortic Repair with Unenhanced MRI: The SAFEVAR Study

<p>Secchi F, Capra D, Monti CB, Mobini N, Ortiz MDMG, Trimarchi S, Mazzaccaro D, Righini P, Nano G, Sardanelli F. Safe Follow-Up after Endovascular Aortic Repair with Unenhanced MRI: The SAFEVAR Study. Diagnostics (Basel). 2022 Dec 21;13(1):20. doi: 10.3390/diagnostics13010020. PMID: 36611311; PMCID: PMC9818075.</p> <p>Abstract</p> <p>We aimed to investigate whether unenhanced magnetic resonance imaging (MRI) could represent a safe and highly sensitive tool for endoleak screening in patients treated with endovascular aneurysm repair (EVAR) using computed tomography angiography (CTA) as a reference standard. Patients who underwent CTA for EVAR follow-up at our institution were prospectively enrolled. All MRI examinations were performed with a 1.5 T unit. The true-FISP and HASTE sequences of the MRI scans were assessed for the presence of hyperintensity within the aneurysm sac outside the graft, whereas phase-contrast through-plane sequences were used for blood flow quantification. We included 45 patients, 5 (11%) of whom were female. The median age was 73 years (IQR 68-78 years). Among our patients, 19 (42%) were positive for endoleaks at CTA, of whom 13 (68%) had type II endoleaks and 6 (32%) had type I endoleaks. There were no significant differences in age, sex, aneurysm type, prosthesis type, or contrast-to-noise ratio between hyperintensity and thrombus between patients with and without endoleaks (<em>p</em>&nbsp;&amp;gt; 0.300). The combined evaluation of true-FISP and HASTE yielded 100% sensitivity (95% CI: 79-100%) and 19% specificity (95% CI: 7-40%). Patients with a positive CTA had a median thrombus flow of 0.06 L/min (IQR 0.03-0.23 L/min), significantly greater than that of patients with a negative CTA (<em>p</em>&nbsp;= 0.007). Setting a threshold at 0.01 L/min, our MRI protocol yielded 100% sensitivity, 56% specificity, and an AUC of 0.76 (95% CI 0.60-0.91). In conclusion, unenhanced MRI has perfect sensitivity for endoleak detection, although with subpar specificity that could be improved with phase-contrast flow analysis.</p>

restrictedJan 2023View details →
zenodo12/100

raw dataset related to the article "Patent foramen ovale closure with the Occlutech Figulla Flex II device: A long-term (up to 10-years) follow-up"

<p><strong>Abstract</strong></p> <p><strong>Background.</strong> Percutaneous closure represents the first line of treatment In patients with cryptogenic stroke and documented patent foramen ovale (PFO). Scarce data report the long-term outcomes of patients undergoing PFO closure with the Figulla Flex II device (Occlutech, Germany).</p> <p><strong>Methods</strong>. Consecutive patients undergoing PFO closure with a Figulla Flex II device at a single, high-volume Institution were included. Baseline clinical and procedural features were collected and patients were followed up for up to 10 years. The device&#39;s long-term safety was assessed, as well as mortality, recurrent cerebrovascular events, new-onset atrial fibrillation (AF) and residual shunt.</p> <p><strong>Results.</strong> Overall, 442 patients were included. The main indication for PFO closure was cryptogenic stroke/transitory ischemic attack (65.5%), followed by migraine (21.7%), silent lesions at MRI (10.8%), and decompression disease (2.0%). Atrial septal aneurysm was present in 20.8% of cases, Eustachian valve in 9.0%, Chiari network in 19.9%. The most frequently implanted device was the 23/25 mm (49.5% of cases). One procedural failure due to device embolization; in-hospital complications occurred in 15 cases (3.4%; 4 minor access site complications, 11 transient supraventricular tachycardias (SVT)/AF). After a follow-up of 9.2 years, 2 patients suffered recurrent TIA (with no residual R-L shunt detected). A moderate or severe residual shunt was observed in 3 patients after discharge.&nbsp;</p> <p><strong>Conclusions</strong>. Figulla Flex II devices for PFO closure are associated with high procedural success and low incidence of adverse events even at long-term follow-up.</p>

restrictedJun 2023View details →
geo12/100

Prenatal diagnosis, ultrasound results, pregnancy outcomes and follow-up information analysis of xp22.31 deletion duplication syndrome

GEO Series GSE299701. Homo sapiens. 21 samples. Type: Genome variation profiling by SNP array.

openGEO-OpenJun 2025View details →
geo12/100

IFNalpha kinoid induces neutralizing anti-IFNalpha antibodies that decrease the expression of IFN-induced and B cell activation associated transcripts: analysis of extended follow-up data from the IFN

GEO Series GSE72798. Homo sapiens. 82 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2016View details →
zenodo8/100

Single Center Five Years' Experience of Ozaki Procedure: Midterm Follow-up

<p>Single Center Five Years&rsquo; Experience of Ozaki Procedure: Midterm Follow-up</p> <p>&nbsp;</p> <p>Background. The Ozaki procedure is an innovative surgical technique aiming at the reconstruction of the aortic valve with autologous pericardium to overcome the limitations of commercially available prostheses. Methods. We retrospectively analyzed 71 patients who underwent the Ozaki operation at our center between October 2014 and February 2020. Results. No in-hospital death occurred. Freedom from major adverse valve-related events was 97%. The aortic gradients and transvalvular velocity were significantly lower at the 3-month echocardiographic control than at the predischarge echocardiography (10.93 &plusmn; 5.38, P &lt; .01 vs 16.24 &plusmn; 7.67, P &lt; .01, respectively). The median follow-up period was 20.7 months (range, 2 to 47). Four patients showed mild/ moderate aortic insufficiency (5.6%), and none showed severe aortic valve insufficiency. No patients underwent reoperation. Conclusions. Midterm outcome follow-up of the Ozaki procedure showed optimal results in terms of mortality, transaortic valve gradients, freedom from major adverse valve-related events, and recurrence of aortic valve insufficiency.</p>

restrictedAug 2020View details →
zenodo8/100

Follow-up assessment of intracranial aneurysms treated with endovascular coiling: comparison of compressed sensing and parallel imaging time-of-flight magnetic resonance angiography

<p>This file contains the data for the paper&nbsp;&quot;Follow-up assessment of intracranial aneurysms treated with endovascular coiling: comparison of compressed sensing and parallel imaging time-of-flight magnetic resonance angiography&quot;</p>

restrictedJun 2022View details →
zenodo8/100

The person in the post-intensive care period: a nursing follow-up model

<p>Retrospective and documentary study through the analysis of the clinical process of people in the post-IC period referred for the follow-up consultation in the period from December 2017 to October 2020. The data collected were subject to descriptive and inferential statistical analysis, using the Statistical Package for the Social Sciences,<em> </em>version 24</p>

restrictedJun 2023View details →
CCDI Data Catalog4/100

Retinoblastoma Survivors Follow-up Study

DCEG researchers are studying survivors of retinoblastoma (Rb), a cancer that forms in the tissues of the retina (the light-sensitive layers of nerve tissue at the back of the eye). Rb usually occurs in children younger than five years and may be hereditary or nonhereditary (sporadic). Sporadic Rb affects just one eye whereas hereditary typically Rb affects both eyes. For the past 30 years, investigators in DCEG have been studying Rb survivors to determine the long-term health effects for these individuals who were treated in childhood. Fortunately, treatment has a very high success rate and many survivors enjoy long productive lives, although some survivors may experience increased risks for developing new cancers.

unknownView details →
dryad0/100

Prevalence, injury-, and non-injury-related predictors of anxiety and depression in polytrauma patients – A 20 year follow-up study

<p class="CxSpFirst"><b>Introduction</b></p> <p class="CxSpMiddle">Survival rate after polytrauma increased over the past decades resulting in an increase of long-term complications. These include physical and psychiatric impairments. The aim of this study was to describe the prevalence and risk factors for developing depression and anxiety more than twenty years after polytrauma.</p> <p class="CxSpMiddle"><b>Methods</b></p> <p class="CxSpMiddle">We contacted patients who were treated due to a polytrauma between 1973 and 1990 at one level 1 trauma centre after more than 20 years. These patients received a self-administered questionnaire, to assess symptoms of depression and anxiety. Prediction based on multivariate logistic regression models include injury related and non-injury related factors to determine risk factors for the development of depression and anxiety.</p> <p class="CxSpMiddle"><b>Results</b></p> <p class="CxSpMiddle">Patients included in this study (n=337) had a mean ISS of 20.3 (4 to 50) points. In total, 173 (51.3%) showed psychiatric complications (depression n=163, 48.2%; anxiety n=14, 4.1%). The maximum Abbreviated Injury Scale (MAIS) for head was predictive for depression (OR 1.5 95%CI 1.1 to 5.4, p = 0.0445) as was the MAIS for spine (OR 1.7, 95%CI 1.2 to 5.9). MAIS spine was also predictive for the development of anxiety (OR 1.4, 95%CI 1.1 to 5.4, p = 0.0456). Non-injury related risk factors for depression include additional insults (OR 6.8, 95%CI 5.3 to 11.7, p = 0.0146); risk factors for the development of anxiety include need for psychiatric treatment after injury (OR 2.6, 95%CI 2.2 to 11.8, p &lt; 0.001).</p> <p class="CxSpMiddle"><b>Conclusion</b></p> <p>More than half of polytrauma patients developed psychiatric complications. Risk factors include injuries to the central nervous system, additional psychiatric insults, and the need of psychiatric treatment.</p>

embargoedcc-zeroJan 2020View details →
dryad0/100

Prevalence, injury-, and non-injury-related predictors of anxiety and depression in polytrauma patients – A 20 year follow-up study

Open the record for dataset details and reuse information.

publicJan 2020View details →

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Allen Brain Atlas

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allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

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abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

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dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record