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77
datasets available to search
ShareScore release 0.9.0
Dataset results
77 results for “ApoE4”
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation
GEO Series GSE217854. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
A novel microglial transcription profile is driven by sex and APOE4 interactions in both mouse and human models of Alzheimer’s disease
GEO Series GSE163857. Mus musculus; Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing.
Spatial transcriptomics Reveals Impact of APOE4 Allele on α-Synuclein Aggregation and Cell-Cell Communication in Lewy Body Dementia
GEO Series GSE293896. Homo sapiens. 10 samples. Type: Other.
An Exhausted-Like Microglial Population Accumulates in Aged and APOE4 Genotype Alzheimer’s Brains
GEO Series GSE239999. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
APOE4 drives transcriptional heterogeneity and maladaptive immunometabolic responses of astrocytes (scRNA-Seq)
GEO Series GSE215444. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
APOE4 drives transcriptional heterogeneity and maladaptive immunometabolic responses of astrocytes (bulk RNA-Seq)
GEO Series GSE215446. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition
GEO Series GSE300079. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
GEO Series GSE242153. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal injury in male mice
GEO Series GSE164688. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of primary tumors from Braf/Pten/Cre APOE2 and APOE4 mice
GEO Series GSE209873. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist
GEO Series GSE242693. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
APOE4 drives transcriptional heterogeneity and maladaptive immunometabolic responses of astrocytes (Spatial)
GEO Series GSE215445. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
APOE4 retinal microglia remain homeostatic in glaucoma.
GEO Series GSE192507. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Neuronal APOE4-induced Early Hippocampal Network Hyperexcitability in Alzheimer’s Disease Pathogenesis
GEO Series GSE279550. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
GEO Series GSE206368. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Functional Interaction between APOE4 and mutant APP promotes cerebrovascular changes in young animals
GEO Series GSE242751. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
SEX-DEPENDENT APOE4 NEUTROPHIL-MICROGLIA INTERACTIONS DRIVE COGNITIVE IMPAIRMENT IN ALZHEIMER'S DISEASE
GEO Series GSE243750. Homo sapiens; Mus musculus. 288 samples. Type: Expression profiling by high throughput sequencing.
APOE4 cell-specific mechanisms underlying cerebrovascular disorder precede neuronal and synaptic dysfunction and cognitive deficits in mice
GEO Series GSE185063. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Study to Evaluate the Effect of HT-4253 for the Prevention of Alzheimer's Disease in APOE4 Carriers
ClinicalTrials.gov study NCT07399171. IPD Sharing: NO. Countries: 1. Publications: 0.
Long-Term Follow-up of Gene Therapy for APOE4 Homozygote Alzheimer's Disease
ClinicalTrials.gov study NCT05400330. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.