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152 results for “DNA viruses”
FIGURE 2 in First record of the West Nile virus bridge vector Culex modestus Ficalbi (Diptera Culicidae) in Belgium, validated by DNA barcoding
FIGURE 2. The small vernal pond vegetated with common cattail (Typha latifolia) where the Cx. modestus larva was collected.
FIGURE 1 in First record of the West Nile virus bridge vector Culex modestus Ficalbi (Diptera Culicidae) in Belgium, validated by DNA barcoding
FIGURE 1. (A) Posterior part of the mounted Cx. modestus larva. Zoom on the diagnostic characteristic of the siphon, showing disarrayed insertion points of the ventral siphonal setae. (B) Posterior part of a mounted Cx. pipiens larva.
Non-invasive surveys of mammalian viruses using environmental DNA
<p class="BodyA">This dataset provides supplemental information to interpret the data published in Alfano & Dayaram et al. 2021. The study investigates how environmental DNA (eDNA) and invertebrate-derived DNA (iDNA) can be used to characterize the yet largely unknown virome present in mammalian wildlife. <span>Environmental DNA and iDNA are used to survey biodiversity non-invasively to mitigate difficulties in obtaining wildlife samples, particularly in remote areas or for rare species. Recently, eDNA/iDNA were used to monitor known wildlife pathogens, however, most wildlife pathogens are unknown and often evolutionarily divergent. To detect and identify known and novel mammalian viruses from eDNA/iDNA, we used a curated set of RNA oligonucleotides as viral baits in a hybridization capture system coupled with high throughput sequencing. We detected multiple known and novel mammalian RNA and DNA viruses from multiple viral families from both waterhole eDNA and leech derived iDNA. Congruence was found between detected hosts and viruses identified in leeches and waterholes. Our results demonstrate that eDNA/iDNA samples represent an effective non-invasive resource for studying wildlife viral diversity and for detecting novel potentially zoonotic viruses prior to their emergence.</span></p>
Study of Covalently Closed Circular DNA (cccDNA) in Liver Transplant Patients With B Virus Markers
ClinicalTrials.gov study NCT02602847. IPD Sharing: Not stated. Countries: 1. Publications: 2.
EPstein-barr Virus DNA Response to Systemic Therapy for Treatment Adaptation in High Risk NPC (EP-STAR)
ClinicalTrials.gov study NCT04072107. IPD Sharing: NO. Countries: 1. Publications: 0.
Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy Volunteers
ClinicalTrials.gov study NCT01984983. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Phase I Open-Label Study of Recombinant DNA Plasmid Vaccine, VRC-AVIDNA036-00-VP, Encoding for Influenza Virus H5 Hemagglutinin Protein Given Intradermally
ClinicalTrials.gov study NCT00489931. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA085-00-VP, in Healthy Adults
ClinicalTrials.gov study NCT02840487. IPD Sharing: Not stated. Countries: 1. Publications: 4.
TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNA
ClinicalTrials.gov study NCT01732367. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Circulating Human Papilloma Virus (HPV) DNA for the Screening and Surveillance of Gynecologic Cancers
ClinicalTrials.gov study NCT05606133. IPD Sharing: NO. Countries: 1. Publications: 6.
VRC 320: A Phase I, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA090-00-VP, Administered Via Needle and Syringe or Needle-free Injector, P
ClinicalTrials.gov study NCT02996461. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Prospective Nasopharyngeal Carcinoma Screening Using Plasma Epstein-Barr Virus DNA Analysis
ClinicalTrials.gov study NCT02063399. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Serial Epstein-Barr Virus DNA Surveillance in Nasopharyngeal Carcinoma Patients
ClinicalTrials.gov study NCT03855020. IPD Sharing: NO. Countries: 1. Publications: 0.
A Trial of Adjuvant Chemotherapy in Nasopharyngeal Carcinoma Patients With Residual Epstein-Barr Virus (EBV) DNA Following Radiotherapy
ClinicalTrials.gov study NCT00370890. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Recurrent evolution of two competing haplotypes in an insect DNA virus
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Non-invasive surveys of mammalian viruses using environmental DNA
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Data from: Distinct spread of DNA and RNA viruses among mammals amid prominent role of domestic species
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Modulation of DNA methyltransferases (DNMTs) in Spodoptera frugiperda (Sf9) cells following AcMNPV infection and its effects on the virus-cell interaction
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Figure 6 from: Todorova N, Rangelov M, Dincheva I, Badjakov I, Enchev V, Markova N (2022) Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase – metabolome profiling, molecular docking and quantum-chemical analysis. Pharmacia 69(1): 113-123. https://doi.org/10.3897/pharmacia.69.e79467
Figure 6 Structures of amino acids from GP phenolic fraction "C", optimized at B3LYP/6-31+G(d,p) level.
Figure 3 from: Todorova N, Rangelov M, Dincheva I, Badjakov I, Enchev V, Markova N (2022) Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase – metabolome profiling, molecular docking and quantum-chemical analysis. Pharmacia 69(1): 113-123. https://doi.org/10.3897/pharmacia.69.e79467
Figure 3 Acyclovir triphosphate and its vicinity in the DNA polymerase pocket after docking procedure: a) 3D plane of view and b) 2D plane of view. The interactions of the ligand in the active site cavity are represented as follows: the proximity contour is depicted with a black dotted line; solvent accessibility, as blue clouds around atoms or blue shadows around amino acid residues; polar amino acids are displayed with pink, while the lipophilic ones are in green. Basic amino acids are outlined with blue and the acidic – with red. Hydrogen bond interactions are depicted with dotted arrows, while the ionic ones are depicted with dotted lines.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.