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Dataset results
339 results for “Diagnostic Test”
Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated Blood
ClinicalTrials.gov study NCT04054661. IPD Sharing: NO. Countries: 1. Publications: 1.
In Vitro Diagnostic Test for DOAC in Urine
ClinicalTrials.gov study NCT03182829. IPD Sharing: NO. Countries: 1. Publications: 5.
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya
ClinicalTrials.gov study NCT04428307. IPD Sharing: NO. Countries: 1. Publications: 3.
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1
ClinicalTrials.gov study NCT03810014. IPD Sharing: NO. Countries: 1. Publications: 1.
ANNE Diagnostic Agreement With Home Sleep Testing
ClinicalTrials.gov study NCT05421754. IPD Sharing: NO. Countries: 1. Publications: 1.
Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis
ClinicalTrials.gov study NCT04666311. IPD Sharing: YES. Countries: 2. Publications: 3.
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria
ClinicalTrials.gov study NCT04428385. IPD Sharing: NO. Countries: 1. Publications: 1.
Diagnostic Performance of an Antigen Test for SARS-CoV-2 Infection (COVID-19)
ClinicalTrials.gov study NCT04610489. IPD Sharing: NO. Countries: 1. Publications: 11.
Primary ciliary dyskinesia multigene NGS diagnostic testing in Cyprus
Open the record for dataset details and reuse information.
Identifying diagnostic genetic markers for a cryptic invasive agricultural pest: a test case using the apple maggot fly, Rhagoletis pomonella (Diptera: Tephritidae)
Open the record for dataset details and reuse information.
MiRoR2 - P2 - Use of test accuracy study design labels in NICE's diagnostic guidance
<p>Data set for the study “Use of test accuracy study design labels in NICE's diagnostic guidance”, including list of the included NICE guidance, data extraction form, extracted data with summary of results, and extraction guidance.</p> <p>Reference to associated article: Olsen M, Zhelev Z, Hunt H, Peters JL, Bossuyt PM, Hyde C. Use of test accuracy study design labels in NICE’s diagnostic guidance. Diagnostic and Prognostic Research. 2019;3:17</p>
Data from: How do patients and health workers interact around malaria rapid diagnostic testing, and how are the tests experienced by patients in practice? A qualitative study in western Uganda
Background: Successful scale-up in the use of malaria rapid diagnostic tests (RDTs) requires that patients accept testing and treatment based on RDT results and that healthcare providers treat according to test results. Patient-provider communication is a key component of quality care, and leads to improved patient satisfaction, higher adherence to treatment and better health outcomes. Voiced or perceived patient expectations are also known to influence treatment decision-making among healthcare providers. While there has been a growth in literature on provider practices around rapid testing for malaria, there has been little analysis of inter-personal communication around the testing process. We investigated how healthcare providers and patients interact and engage throughout the diagnostic and treatment process, and how the testing service is experienced by patients in practice. Methods: This research was conducted alongside a larger study which explored determinants of provider treatment decision-making following negative RDT results in a rural district (Kibaale) in mid-western Uganda, ten months after RDT introduction. Fifty-five patients presenting with fever were observed during routine outpatient visits at 12 low-level public health facilities. Observation captured communication practices relating to test purpose, results, diagnosis and treatment. All observed patients or caregivers were immediately followed up with in-depth interview. Analysis followed the 'framework' approach. A summative approach was also used to analyse observation data. Results: Providers failed to consistently communicate the reasons for carrying out the test, and particularly to RDT-negative patients, a diagnostic outcome or the meaning of test results, also leading to confusion over what the test can detect. Patients appeared to value testing, but were frustrated by the lack of communication on outcomes. RDT-negative patients were dissatisfied by the absence of information on an alternative diagnosis and expressed uncertainty around adequacy of proposed treatment. Conclusions: Poor provider communication practices around the testing process, as well as limited inter-personal exchange between providers and patients, impacted on patients' perceptions of their proposed treatment. Patients have a right to health information and may be more likely to accept and adhere to treatment when they understand their diagnosis and treatment rationale in relation to their perceived health needs and visit expectations.
Percussion test: description and diagnostic accuracy of a new manual test for bone marrow edema of the knee - RAW DATASET
<p>Background</p> <p>Prompt diagnosis of bone marrow lesion (BML) is difficult but critical for correct treatment. Magnetic resonance imaging is the gold standard, although expensive and time consuming. Simple and reliable clinical test for BML detection is lacking. Aim of the study is to describe a new manual clinical test called Percussion Test (PT) and to statistically determine its diagnostic accuracy in BML, compared to MRI imaging.</p> <p>Methods</p> <p>After evaluation of the inclusion and exclusion criteria, 218 consecutive patients with unilateral knee pain and age comprised between 18 and 80 years old were enrolled in our observational prospective study. Informed consent was obtained for each patient. After medical history collection, PT was performed by a single operator as described. MRI was performed in the affected knee to detect the presence of BML. Coherence in PT and MRI assessment was evaluated in each quadrant of the knee via contingency tables, as sensitivity, specificity, NPV, PPV and diagnostic accuracy were calculated.</p> <p>Results</p> <p>No correlation with a positive PT was demonstrated for the covariables gender (<em>p</em> =&thinsp;0.156), age (<em>p</em> =&thinsp;0.272) and BMI (<em>p</em> =&thinsp;0.639).</p> <p>PT showed a sensitivity ranging from 60.6 (40.6–80.6) to 79.5 (63.0–96.0) and a specificity ranging from 85.7 (80.0–91.5) to 96.0 (93.1–98.9) depending on knee quadrant. Diagnostic accuracy ranged from 81.6 (75.9–86.6) to 89.4 (84.6–93.2), and <em>p</em>-value was < 0.00001 in a chi-squared analysis for all quadrants.</p> <p>Conclusions</p> <p>PT showed sensitivity and specificity values that are comparable with other clinical tests routinely adopted in clinical practice. In the absence of other reliable clinical test, PT has the potential to become a useful bedside tool in the diagnosis and management of BMLs.</p>
Quality criterias for a diagnostic test
<p>The figure illustrates <strong>the quality criteria for a diagnostic test</strong>:</p> <ul> <li>Sensitivity and specificity as pre-probability before the test is used in routine practice</li> <li>Positive and negative predictive value as post-probability interpretation of the result </li> </ul> <p><strong>A diagnostic test</strong> is a diagnostic tool with a binary output, i.e. yes/no, sick/healthy, suitable/unsuitable or positive/negative. </p> <p><strong>Explanation</strong></p> <p>Before being used in diagnostics or screening, the two parameters of the diagnostic test <strong>sensitivity </strong>and <strong>specificity </strong>are determined. This is done on (known) sick or infected and healthy or non-infected persons. In the case of sick persons, the statistical measures of true-positive and false-positive are also obtained. In the case of healthy persons, the statistical measures true-negative and false-negative are also obtained.</p> <p>After the test has been performed, <strong>the positive predictive value</strong> indicates the probability that, if the test result is positive, the person is actually sick or infected (post-test probability).</p> <p>After the test has been carried out, <strong>the negative predictive value</strong> indicates the probability that, in the case of a negative test result, the person is actually healthy or non-infected (post-test probability).</p>
Diagnostic test: 4-field table
<p>A <strong>diagnostic test </strong>is a diagnostic instrument with a binary output or result: yes/no or positive/negative.</p> <p>The input state (condition) is also binary, e.g. healthy/diseased, not infected/infected, suitable/not suitable, etc.</p> <p>Both factors, <strong>condition</strong> and <strong>test result</strong>, are shown in a 4-field table. The outcome of the condition and test are 4 cells (2x2): true positive (TP) and false positive (FP) as well as true negative (TN) and false negative (FN).</p> <p>Depending on the reading - rows or columns - both <strong>sensitivity and specificity</strong> (pre-test probabilities) as well as <strong>positive and negative predictive value</strong> (post-test probabilities) can be read from the table.</p> <ul> <li>sensitivity: TP/(TP+FN)</li> <li>specificity: TN/(TN+FP)</li> <li>positive predictive value: TP/(TP+FP)</li> <li>negative predictive value: TN/(TN+FN)</li> </ul>
Diagnostic accuracy of Panbio™ rapid antigen test for SARS-CoV-2 in paediatric population
<p>The aim was to evaluate the accuracy of the Panbio<sup>TM</sup> Rapid Antigen Test for SARS-CoV-2 in the setting of a primary health care centre (PHC) in paedriatic population, with use of the Reverse Transcription-Polymerase Chain Reaction (RT-PCR) as gold standard.</p>
Translation of a Diagnostic Test for Lupus Flare Prediction From Bench to Clinic
ClinicalTrials.gov study NCT04018222. IPD Sharing: NO. Countries: 1. Publications: 2.
Diagnostic Role of the "White Test" With Lipidic Solution in the Early Intraoperative Identification of Open Bile Ducts for the Prevention of Bile Leakage After Liver Resection (BiLe -Trial)
ClinicalTrials.gov study NCT04523701. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Diagnostics of COVID-19/DARTS (Development and Assessment of Rapid Testing for SARS-CoV-2 Outbreak)
ClinicalTrials.gov study NCT04351646. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Validation of a Salivary miRNA Diagnostic Test for ASD
ClinicalTrials.gov study NCT05418023. IPD Sharing: Not stated. Countries: 1. Publications: 3.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.