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79 results for “Glycocalyx”
Comparison of Liberal and Restrictive Fluid Management on the Endothelial Glycocalyx in Radical Cystectomy
ClinicalTrials.gov study NCT04780490. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Glycocalyx Levels in Patients Undergoing Pancreatectomy
ClinicalTrials.gov study NCT04058236. IPD Sharing: NO. Countries: 1. Publications: 15.
Glycocalyx and Microcirculation in Sepsis
ClinicalTrials.gov study NCT03960307. IPD Sharing: NO. Countries: 1. Publications: 1.
Endothelial glycocalyx layer properties and its ability to limit leukocyte adhesion
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Data from: Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication
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Data from: Diosmin and its glycocalyx restorative and anti-inflammatory effects on injured blood vessels
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Data from: Serum levels of endothelial glycocalyx constituents in women at 20 weeks' gestation who later develop gestational diabetes mellitus compared to matched controls: a pilot study
Objectives: The aim of this pilot study was to determine the serum concentration of heparan sulfate, hyaluronan, chondroitin sulfate and syndecan-1 and if these serum concentrations can be used to identify women at 20 weeks' gestation who later develop gestational diabetes mellitus (GDM). Design: Nested case–control study from Auckland, New Zealand participants in the prospective cohort Screening for Pregnancy Endpoints study. Setting: Auckland, New Zealand. Participants: 20 pregnant women (70% European, 15% Indian, 10% Asian, 5% Pacific Islander) at 20 weeks' gestation without any hypertensive complications who developed GDM by existing New Zealand criteria defined as a fasting glucose ≥5.5 mmol/L and/or 2 hours ≥9.0 mmol/L after a 75 g Oral Glucose Tolerance Test. Women not meeting these criteria were excluded from this study. The patients with GDM were matched with 20 women who had uncomplicated pregnancies and negative screening for GDM and matched for ethnicity, maternal age and BMI. Primary and secondary outcome measures: The primary measures were the serum concentrations of syndecan-1, heparan sulfate, hyaluronan and chondroitin sulfate determined by quantitative ELISA. There were no secondary outcome measures. Results: Binary logistic regression was performed to determine if serum concentrations of endothelial glycocalyx layer constituents in women at 20 weeks' gestation would be useful in predicting the subsequent diagnosis of GDM. The model was not statistically significant χ2=12.5, df=8, p=0.13, which indicates that the model was unable to distinguish between pregnant women at 20 weeks' gestation who later developed GDM and those who did not. Conclusions: Serum concentrations of syndecan-1, heparan sulfate, hyaluronan and chondroitin sulfate in pregnant women at 20 weeks' gestation were not associated with later development of GDM. To further explore whether there is any relationship between endothelial glycocalyx constituents and GDM, the next step is to evaluate serum concentrations at the time diagnosis of GDM.
Targeting the Endothelial Glycocalyx to Enhance Vascular Function and Exercise-Induced Vascular Adaptations in Type 2 Diabetes
ClinicalTrials.gov study NCT05205005. IPD Sharing: YES. Countries: 1. Publications: 0.
Glycocalyx Damage in Critically Ill Patients
ClinicalTrials.gov study NCT03146585. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effect General and Regional Anesthesia on Glycocalyx
ClinicalTrials.gov study NCT02783443. IPD Sharing: YES. Countries: 0. Publications: 0.
Data from: Serum levels of endothelial glycocalyx constituents in women at 20 weeks’ gestation who later develop gestational diabetes mellitus compared to matched controls: a pilot study
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Enhancing the anti-tumor efficacy of Bispecific T cell engagers via cell surface glycocalyx editing
GEO Series GSE245991. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Markers of endothelial glycocalyx dysfunction in Clarkson disease
GEO Series GSE204882. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Tumor Acidosis Remodels the Glycocalyx to Control Lipid Scavenging and Ferroptosis
GEO Series GSE300142. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies [RNA-seq]
GEO Series GSE249573. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
IL-22 promotes formation of MUC17 glycocalyx barrier in postnatal small intestine during weaning
GEO Series GSE164552. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome
GEO Series GSE186705. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Loss of the Endothelial Glycocalyx Component EMCN Leads to Glomerular Impairment
GEO Series GSE271432. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Modulation of lncRNA links endothelial glycocalyx to vascular dysfunction of tyrosine kinase inhibitors [dataset 1]
GEO Series GSE216452. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Flow upregulates glycocalyx-related genes and makes surface charge more negative of a human blood-brain barrier co-culture model in an organ-on-a-chip device
GEO Series GSE155671. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
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