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253
datasets available to search
ShareScore release 0.9.0
Dataset results
253 results for “Hospital infections”
A Study to Evaluate the Efficacy and Safety of Pimodivir in Combination With the Standard-of-Care Treatment in Adolescent, Adult, and Elderly Non-Hospitalized Participants With Influenza A Infection W
ClinicalTrials.gov study NCT03381196. IPD Sharing: Not stated. Countries: 38. Publications: 1.
A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection
ClinicalTrials.gov study NCT02532283. IPD Sharing: Not stated. Countries: 15. Publications: 1.
Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections
ClinicalTrials.gov study NCT01499290. IPD Sharing: Not stated. Countries: 20. Publications: 9.
A Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respira
ClinicalTrials.gov study NCT03379675. IPD Sharing: Not stated. Countries: 19. Publications: 1.
Characteristics of Respiratory Syncytial Virus infections in children in the Post-COVID seasons: a Northern Italy Hospital experience.
<p>Background: Public health measures for COVID-19 mitigation influenced the circulation of Respiratory Syncytial Virus (RSV) during the 2020-2021 winter season. In the following autumn, an unprecedented resurgence of RSV occurred. In our study we monitored RSV pediatric infections, one and two years after the relaxation of containment measures for COVID-19 pandemics. Methods: we analyzed diagnostic molecular data for SARS-CoV-2, Flu and RSV infections and clinical data from children with respiratory symptoms referring to our hospital during 2021-2022 and 2022-2023 seasons. Results: In 2021-22 season, the number of RSV affected children was very high, especially for babies <1 year. The outbreak appeared in a shorter interval of time, with a high clinical severity. In the 2022-23 season, a reduced number of infected pediatric patients were detected, with a similar hospitalization rate (46% vs 40%) and RSV accounted for 12% of the infections. Coinfections were observed in age <2 years. In RSV patients, symptoms were similar across the two seasons. Conclusions: clinical presentation of RSV in the two post-COVID seasons suggests that the pathophysiology of the virus did not change across these two years. Further studies are needed to continuously monitor RSV, for supporting an effective prevention strategy.</p>
Prevalence, resistance profiles and factors associated with skin and soft-tissue infections at Jinja regional referral hospital: A retrospective study
<p>Skin and soft-tissue infections (SSTI) are common cases of hospital-acquired infections with aetiologic agents exhibiting antimicrobial resistance (AMR). We determined the prevalence, proportion of laboratory-investigated cases, AMR-profiles, and factors associated with SSTI and multi-drug resistance (MDR). This study was based on archived data of patients suspected of SSTI from 2019-2021 at Jinja Regional Referral Hospital. The analysis involved 268 randomly selected patient reports. Prevalence of SSTI was 66.4%. Laboratory-investigated cases were 14.11%. <em>Staphylococcus aureus </em>(n=51) was the most isolated organism. MDR pathogens explained 47% of infections. Methicillin-resistant <em>S. aureus</em> was up to 44%. In addition, 61% of Gram-negatives had the potential to produce extended-spectrum beta-lactamases, while 27% were non-susceptible to carbapenems. Ward of admission was significantly associated with infection (aPR=1.78, 95% CI: 1.003-3.18, p-value=0.04). Age category <u>(</u>19-35) was an independent predictor for MDR infections (aPR=2.30, 95%CI:1.02-5.23, p-value=0.04). The prevalence is relatively high with MDR pathogens responsible for almost half of the infections. Routine use of culture and sensitivity testing should be done for proper infection management. Gentamicin and ciprofloxacin can be considered for empirical management of emergency SSTI suspected of <em>S. aureus</em>. Recognizing SSTI under the Global Antimicrobial resistance Surveillance System (GLASS) would lead to improved preparedness and response to AMR.</p>
Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection
ClinicalTrials.gov study NCT04636086. IPD Sharing: NO. Countries: 1. Publications: 20.
Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection
ClinicalTrials.gov study NCT04508439. IPD Sharing: NO. Countries: 1. Publications: 1.
Pre-hospital Risk Factors for Invasive Fungal Infection
ClinicalTrials.gov study NCT01315925. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19
ClinicalTrials.gov study NCT04414631. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia
ClinicalTrials.gov study NCT04522076. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants, Ages 2 to <12 Years, With Confirmed or Suspected Bacterial Infection (MK-1986-013)
ClinicalTrials.gov study NCT02750761. IPD Sharing: YES. Countries: 0. Publications: 1.
Analysis of Single Respiratory Viral Infections Versus Co-infections: Prevalence and ICU Needs in Hospitalized Adults
ClinicalTrials.gov study NCT06779175. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs
ClinicalTrials.gov study NCT04459351. IPD Sharing: NO. Countries: 1. Publications: 2.
Smoking Ban and Paediatric Hospital Admissions for Respiratory Tract Infections in England
ClinicalTrials.gov study NCT01920165. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Epidemiology and Determinants of Outcomes of Hospital Acquired Blood Stream Infections in the Intensive Care
ClinicalTrials.gov study NCT03937245. IPD Sharing: UNDECIDED. Countries: 2. Publications: 3.
Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users
ClinicalTrials.gov study NCT01612169. IPD Sharing: YES. Countries: 1. Publications: 8.
The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital
ClinicalTrials.gov study NCT02904252. IPD Sharing: NO. Countries: 1. Publications: 8.
COG-UK Project Hospital-Onset COVID-19 Infections Study
ClinicalTrials.gov study NCT04405934. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study on Rare Dermatological Infections Conducted at Three Major Reference Hospitals in Costa Rica.
ClinicalTrials.gov study NCT06523998. IPD Sharing: NO. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
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