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47
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ShareScore release 0.9.0
Dataset results
47 results for “Human history”
Study of Natural History of Human Papillomavirus (HPV) Infections in Adult Women With Recurrent Conizations in Norway
ClinicalTrials.gov study NCT00924794. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Fire history in a western Fennoscandian boreal forest as influenced by human land use and climate
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Data from: Rapid human-induced divergence of life-history strategies in Bahamian livebearing fishes (family Poeciliidae)
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Data from: Larval nutritional stress affects vector life history traits and human malaria transmission
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Data from: When new human-modified habitats favor the expansion of an amphibian pioneer species: evolutionary history of the natterjack toad (Bufo calamita) in a coal basin
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Data from: A genetic assessment of the human-facilitated colonization history of black swans in Australia and New Zealand
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Data from: Diatraea saccharalis history of colonization in the Americas. The case for human-mediated dispersal
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Data from: Long livestock farming history and human landscape shaping revealed by lake sediment DNA
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Data from: Demographic history and adaptation account for clock gene diversity in humans
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Data from: Human-mediated evolution in a threatened species? Juvenile life-history changes in Snake River salmon
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Marginal imprint of human land use upon fire history in a mire-dominated boreal landscape of the Veps Highland, North-West Russia
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Data from: An evolutionary history of the selectin gene cluster in humans
Molecules involved in leukocyte trafficking have a central role in the development of inflammatory and immune responses. We performed FST analysis of the selectin cluster, as well as of SELPLG, ICAM1 and VCAM1. Peaks of significantly high population genetic differentiation were restricted to two regions in SELP and one in SELPLG. Resequencing data indicated that the region covering SELP exons 11–13 displays high nucleotide diversity in Africans and Europeans (CEU), and a high level of within-species diversity compared with inter-specific divergence. Analysis of inferred haplotypes revealed a complex phylogeny with two deeply separated clades that coalesce at ~3.5 million years (MY) plus a minor clade with a TMRCA (time to the most recent common ancestor) of ~2.2 MY. A splicing assay indicated no haplotype-specific effect on SELP exon 14 inclusion. These data are consistent with a model of multiallelic balancing selection; single-nucleotide polymorphism analysis indicated that the Val640Leu variant represents a likely selection target. In populations of Asian ancestry a distinct haplotype, possibly carrying regulatory variants, has been driven to high frequency by positive selection. No deviation from neutrality was observed for the SELPLG region. Resequencing of SELP in chimpanzees revealed a haplotype phylogeny with extremely deep basal branches, suggesting either long-standing balancing selection or ancestral population structure. Thus, SELP has experienced a complex selective history, possibly as a result of local adaptation. Variants in the gene have been associated with autoimmune and cardiovascular diseases. Association studies would benefit from both taking the complex SELP haplotype structure into account and from analysis of possible regulatory variants in the gene.
NATURAL HISTORY-Hepatitis C Virus/ Human Immunodeficiency Virus Coinfection
ClinicalTrials.gov study NCT00315432. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Data from: An evolutionary history of the selectin gene cluster in humans
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Data from: Effects of the demographic transition on the genetic variances and covariances of human life history traits
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Data from: Modeling human population separation history using physically phased genomes
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A genetic atlas of human admixture history
GEO Series GSE53626. Homo sapiens. 158 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Kazak mitochondrial genomes provide insights into the human population history of Central Eurasia
GEO Series GSE208402. Homo sapiens. 80 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
Spatial transcriptomics of human dorsal root ganglia from subjects with a history of diabetes
GEO Series GSE295206. Homo sapiens. 16 samples. Type: Other.
Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)
ClinicalTrials.gov study NCT01295242. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.