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991 results for “Inflammatory response”
The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
ClinicalTrials.gov study NCT02848599. IPD Sharing: NO. Countries: 1. Publications: 24.
Effect of Eplerenone on Postprandial Inflammatory Response in Healthy Adults
ClinicalTrials.gov study NCT01786551. IPD Sharing: Not stated. Countries: 1. Publications: 1.
<em>Mycobacterium tuberculosis</em> triggers reduced inflammatory cytokine responses and virulence in mice lacking Tax1bp1
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An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo
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Data for: Pro-Inflammatory response to macrotextured silicone implant wear debris
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Inflammatory responses induced by the monophasic variant of Salmonella typhimurium in pigs play a role in the high shedder phenotype and fecal microbiota composition
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Normal Saline versus Lactated Ringer's Solution: Effects on Organ Function and Inflammatory Responses in Heat Stroke in Rat
<p>The data set includes the data generated during the experiment, including vital signs, test indicators, etc. The image file includes the expression of inflammasome proteins measured using WB.</p>
Cartilage Responses to Inflammatory Stimuli and Adipose Stem/Stromal Cell-Derived Conditioned Medium: Results from an Ex Vivo Model
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Fig 5 in Docosahexaenoic Acid (DHA) Reduces LPS-Induced Inflammatory Response Via ATF3 Transcription Factor and Stimulates Src/Syk Signaling-Dependent Phagocytosis in Microglia
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Fig 3 in Docosahexaenoic Acid (DHA) Reduces LPSInduced Inflammatory Response Via ATF3 Transcription Factor and Stimulates Src/ Syk Signaling-Dependent Phagocytosis in Microglia
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Fig 4 in Docosahexaenoic Acid (DHA) Reduces LPS-Induced Inflammatory Response Via ATF3 Transcription Factor and Stimulates Src/Syk Signaling-Dependent Phagocytosis in Microglia
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Data from: Pro-inflammatory immune response is linked to wintering habitat in a migratory shorebird
<p><span>Migratory shorebirds (Charadrii) show a strong dichotomy in their breeding and wintering strategies: Arctic-breeding species typically spend the wintering season in marine habitats, while more southerly breeding species tend to do so in freshwater habitats where pathogens and parasites, particularly vector-borne blood parasites, are generally more abundant. Thus, it has been hypothesized that the former group may reduce their investment in immunity, but experimental data supporting this hypothesis are lacking. Moreover, whether this contrasting habitat selection can shape investments in immunocompetence among populations within a species is uncertain. We experimentally tested the hypothesis that there is a significant association between habitat occupancy and the strength of a pro-inflammatory immune response in Dunlins <i>Calidris alpina</i>, a widely distributed long-distance migratory shorebird that breeds in (sub-)arctic areas and winters mainly, but not exclusively, in coastal habitats. Overwintering Dunlins occupying inland freshwater and marine habitats at a similar latitude were captured and acclimated under identical conditions in outdoor aviaries. After an acclimation period, they were challenged with phytohemagglutinin to assess the pro-inflammatory immune response and its associated energetic costs, measured by basal metabolic rate (BMR) and body mass changes. We found that freshwater Dunlins exhibited a higher (63%) pro-inflammatory immune response than marine Dunlins. Although this difference did not involve significant BMR changes, the time course of body mass response differed between freshwater and marine individuals. Our findings point to the existence of different pro-inflammatory immune and energetic strategies associated to the wintering habitat. These intraspecific differences are likely due to population adaptation rather than phenotypic plasticity, where not only disease risk but also physiological adaptations to different salinity levels could play an important role. </span></p>
FIG. 3 in A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance
FIG. 3. Bat-specific sites under positive selection in the investigated immune genes. Sites that had statistically significant evidence of positive selection acting across eutherian mammals were investigated for any amino acid substitutions unique to the ancestral bat lineage, the vespertilionid lineage or the pteropodid lineage. Bat lineages-specific sites are highlighted in yellow
FIG. 2 in A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance
FIG. 2. Signatures of adaptive evolution in genes involved in sensing of viral infection and activation of antiviral/proinflammatory signalling. Genes under positive selection (site-test) in mammals are highlighted in green. Genes with sites under positive selection in bat lineages are indicated with an asterix
FIG. 1. Myotis myotis and M in A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance
FIG. 1. Myotis myotis and M. musculus macrophages present differential response to LPS and Poly(I:C) challenge. Change in gene expression of A — IFN-β, B — IL-1β, C — TNF, D — Il-10 in response to LPS and Poly(I:C) treatment at 1, 4 and 24 hr time points are presented as changes in delta Ct values normalized to actin-β. Ratios of the fold induction of anti-inflammatory Il-10 to proinflammatory TNF (E) and Il-1β (F) are also presented. G — Literature derived Il-10/TNF ratios for other mammals. H — NO generated by stimulated M. myotis and mouse macrophages. Bars represent the mean of two experimental repeats ± SEM. Presented P -values indicate the significance of the difference between species from analysis of variance (ANOVA)
Inflammatory Response to Opioid Versus Opioid Free Anesthesia
ClinicalTrials.gov study NCT04854252. IPD Sharing: NO. Countries: 1. Publications: 1.
Chronic Inflammatory Disease, Lifestyle and Treatment Response
ClinicalTrials.gov study NCT03173144. IPD Sharing: YES. Countries: 1. Publications: 4.
Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers
ClinicalTrials.gov study NCT02902315. IPD Sharing: NO. Countries: 1. Publications: 14.
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
ClinicalTrials.gov study NCT01143519. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders
ClinicalTrials.gov study NCT06450704. IPD Sharing: NO. Countries: 1. Publications: 12.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.