Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,183
datasets available to search
ShareScore release 0.9.0
Dataset results
1,183 results for “Insertion”
Uncovering structural plasticity of Enterovirus A through deep insertional and deletional scanning
<p>Insertions and deletions (InDels) are essential sources of novelty in protein evolution. In RNA viruses, InDels cause dramatic phenotypic changes that contribute to the emergence of viruses with altered immune profiles and host engagement. This work aims to comprehensively quantify the mutational tolerance of an RNA virus to insertion, deletion, and substitution. Using Enterovirus A71 (EV-A71) as a prototype for the Enterovirus A species (EV-A) of picornaviruses, we engineered approximately 45,000 insertions, 6,000 deletions, and 41,000 amino acid changes across the 2,193 coding positions of the EV-A71 proteome, quantifying their effects on viral fitness and comprehensively mapping evolutionary constraint across the viral proteome. In contrast with amino acid changes, the vast majority of InDels are lethal to virus growth. Most that are tolerated reside at a few hotspot regions. These tolerant sites highlight structurally flexible and mutationally plastic regions of EV-A71 proteins that avoid core structural and functional elements, but often overlap with key sites of host- and immune recognition, suggesting a complex evolutionary role for InDels and substitutions at these sites. Phylogenetic analysis examining EV-A species isolated from diverse mammalian hosts reveals that many of the experimentally identified hotspots also correspond to sites of natural InDel diversity across the more diverse EV-A species, suggesting these hotspots of mutational tolerance in EV-A genomes may have contributed to past phenotypic diversification of EV-A. Insights from this and future mutational scanning studies mapping viral evolutionary potential will inform better epidemiological monitoring and Enterovirus vaccine development.</p>
BRAIN Journal-High Performance Data mining by Genetic Neural Network-Figure 5. Insertion and Deletion Hidden Layer in NN
<p>Change in NN structure is other method that we used to optimization of solution[18].<br> Insertion a hidden layer caused to mutation operator is much natural. As connection with father and<br> mother nodes is easily[20],[21]. Weights of node and errors automatically calculated.<br> For each stage of the implementation of the mutation operator in genetic algorithms, neural<br> networks, only one of the nodes in the hidden layer is selected and inserted. These layers are<br> inserted on condition that the definition does not harm the network structure and the action is<br> meaningful. As an added layer can adjust the weights and the connection to the parent node of a network<br> layer to be removed.</p>
BRAIN Journal-A Combination of Meta-heuristic and Heuristic Algorithms for the VRP, OVRP and VRP with Simultaneous Pickup and Delivery- Figure 2. Insert (left), swap (middle) and 2-opt exchanges (right)
<p> The literature on meta-heuristics indicates that a promising approach for obtaining highquality solutions is to couple a local search algorithm with a mechanism to generate initial solutions. So, after all ants have constructed their routes and before updating global pheromone, three types of local search schemes including 2- opt scheme, insert and swap moves are performed to further reduce the routes length (Figure 2). In insert algorithm, a customer is moved to another route but in swap algorithm a customer in a certain route is swapped with another customer from a different route. One of the most commonly encountered moves is the 2-opt which starts with a feasible tour and continues by omitting two arcs of the same route, which are not adjacent and then connects them again by another method in such a way that the new tour length is shorter. In multiple routes, two edges belong to different routes, which form a criss-cross, are selected and two new edges are replaced. It also should be noted that the new solution will be only accepted in state that first, the constraints are not violated specially about each vehicle’s capacity. It can be noted that there are several routes for connecting nodes and producing the tour again, but a state that satisfies the problem’s constraints is acceptable</p>
Sample datasets for Transposon insertion sequencing analysis tutorial
<p>The dataset contains five files:</p> <ol> <li>Tnseq-Tutorial-reads.fastqsanger.gz - A subset of TnSeq reads published in `Santiago, M., Matano, L. M., Moussa, S. H., Gilmore, M. S., Walker, S., & Meredith, T. C. (2015). A new platform for ultra-high density Staphylococcus aureus transposon libraries. <em>BMC Genomics</em>, <em>16</em>(1), 1–18. http://doi.org/10.1186/s12864-015-1361-3`</li> <li>condition_barcodes.fasta - Set of barcodes to separate reads from different experimental conditions</li> <li>construct_barcodes.fasta - Set of barcodes to separate reads from different transposon constructs</li> <li>staph_aur.fasta : Genome file for <em>Staphylococcus aureus </em></li> <li>staph_aur.fasta : Annotation file for <em>Staphylococcus aureus </em></li> </ol>
anatomical measurement of cervical lateral mass for cervical pedicle screw and paravertebral foramen screw insertion
<p>The anatomical pedicle transverse angle (PTA) and linear parameters of the lateral mass were measured, and the relationship between the calculated angles and the anatomical PTA was investigated. θp was defined as the convergence angle from the posterolateral edge of the lateral mass to the pedicle, and θc was defined as the convergence angle from the posterolateral edge of the lateral mass to the anterolateral corner of the vertebral foramen. The thickness of the cortical bone of the medial wall of the lateral mass (cT) and the medial (mT) and lateral (lT) walls of the pedicle at C3–7 were also measured.</p>
Figure 1. Insert showing a in Distribution of blackchin guitarfish Rhinobatos cemiculus E. Geoffroy Saint-Hilaire, 1817 (Elasmobranchii: Rhinobatidae) with first records from İzmir Bay (Turkey, northeastern Aegean Sea)
Figure 1. Insert showing a map of the Mediterranean Sea including the Aegean Sea and the study area (black circle). Map of İzmir Bay indicating the capture sites of both Rhinobatos cemiculus (1 = large female; 2 = large male).
Text-fig. 1. Rhinoppioides quadrituberculatus MIKO gen. et sp. nov. A – dorsal view of holotype (prodorsal setae largely missing except right lamellar seta, notogastral setae missing and their insertions not discernable); B – ventral view of holotype (genital and anal valves missing, only insertions of ventral setae visible, gnathosoma missing); C – lateral view of paratype (notogaster missing). Bar indicates 100 µm. For explanation of acronyms see page 31. in Oribatid Mite Fossils From Quaternary And Pre-Quaternary Sediments In Slovenian Caves I.Two New Genera And Two New Species Of The Family Oppiidae From The Early Pleistocene
Text-fig. 1. Rhinoppioides quadrituberculatus MIKO gen. et sp. nov. A – dorsal view of holotype (prodorsal setae largely missing except right lamellar seta, notogastral setae missing and their insertions not discernable); B – ventral view of holotype (genital and anal valves missing, only insertions of ventral setae visible, gnathosoma missing); C – lateral view of paratype (notogaster missing). Bar indicates 100 µm. For explanation of acronyms see page 31.
Research Data for the Journal Article: Insertion of CO2 to 2-methyl furoate promoted by a cobalt hypercrosslinked polymer catalyst to obtain a monomer of CO2-based biopolyesters
Open the record for dataset details and reuse information.
Generation of transcriptional novelty by transposable element insertions in Arabidopsis, RNAseq Control Condition Sequencing Data
<p><strong>Arabidopsis stranded 150 bp paired end RNA sequencing data (Illumina) of plants that were grown under control conditions for the manuscript "Generation of transcriptional novelty by transposable element insertions in Arabidopsis"</strong></p> <p><strong><strong>Plant growth conditions</strong></strong></p> <p>Sequenced F4 seeds were sterilized for 10 minutes in 10% bleach, rinsed, and stratified at 4°C for four days in the dark before being sown on 0.5x Murashige & Skoog media (Du<em>schefa cat# M0222</em>) and transferred to growth chambers under long day conditions (16h of light at 24°C followed by 8h of darkness at 21°C; 20 seeds per plate, 6 replicate plates). Ten days after sowing, plants were subjected to 6°C for 24 hours and control plants were returned to normal long day growing conditions for 24 hours before harvesting (3 replicate plates per condition).</p> <p><strong><strong>RNA extraction and sequencing</strong></strong></p> <p>Seedlings were harvested and RNA extractions were done on pools of 5 plants. RNA extractions were performed for 3 biological replicate samples for each line in each condition (n=96) using the Macherey-Nagel NucleoSpin RNA kit (cat# 740955.50). Samples were sent to Novogene for Illumina 150bp paired-end sequencing using a stranded poly-A library.</p> <p><strong>RNAseq sample descriptions of the plants grown under control conditions</strong></p> <p>wt_control: wild-type plants.</p> <p>wtHS_control: wild-type plants that have been submitted to heat stress in a previous generation.</p> <p>wtAZ_control: wild-type plants that have been submitted to epigenetic drug treatments (alpha-amanitin and zebularine) in a previous generation.</p> <p>htLine#: plants carrying additional <em>ONSEN</em> transposable element insertions.</p> <p>Files description: Forward and reverse strand RNA seq data are combined in one file. The numbering at the end ("_1") denominates the biological replicate number.</p>
Text-fig. 3. Schematic position of the human modifications (cut marks, impact marks, ochre traces, inserted bones) recognised on the canid remains from Předmostí, indicated on a wolf skeleton; the frequencies of the modifications are not shown. Modified after © 2003 ArcheoZoo.org / Michel Coutureau (Inrap). in Consumption Of Canid Meat At The Gravettian Předmostí Site, The Czech Republic
Text-fig. 3. Schematic position of the human modifications (cut marks, impact marks, ochre traces, inserted bones) recognised on the canid remains from Předmostí, indicated on a wolf skeleton; the frequencies of the modifications are not shown. Modified after © 2003 ArcheoZoo.org / Michel Coutureau (Inrap).
Text-fig. 2. Metacheiromys marshii, AMNH 131777, drawing of basicranium in ventral view with isosurface from CT scans of left petrosal inserted (compare with Simpson 1931: fig. 7). Much of the mastoid exposure on the specimen's left side is damaged. Numbers 1 to 4 indicate depressions that based on the right side include a thin layer of entotympanic; 1 to 3 are between petrosal and basioccipital and 4 is petrosal only. The white arrow in the lower left passes through a canal between the petrosal and exoccipital for the auricular branch of the vagus nerve. Abbreviations: abX – grooves and foramina for auricular branch of vagus nerve, as – alisphenoid, astp – alisphenoid tympanic process, bo – basioccipital, bs – basisphenoid, eam – roof of external acoustic meatus, ec – ectotympanic, en – entotympanic, eo – exoccipital, es – epitympanic sinus of squamosal, fm – foramen magnum, fo – foramen ovale, gf – glenoid fossa, hf – hypoglossal foramen, ips – foramen for inferior petrosal sinus, ljf – lateral jugular foramen, me – mastoid exposure of petrosal, mjf – medial jugular foramen, mt – muscular tubercle, mtc – musculotubal canal, oc – occipital condyle, pa – porus acousticus (hidden), pas – parasphenoid, pgp – postglenoid process, pr – promontorium of petrosal, ps – presphenoid, smf – stylomastoid foramen, sof – superior orbital fissure, sq – squamosal, tca – tympanic canaliculus, th – tympanohyal, tm – tubular external acoustic meatus. in Skeletal Anatomy Of The Basicranium And Auditory Region In The Metacheiromyid Palaeanodont Metacheiromys (Mammalia, Pholidotamorpha) Based On High-Resolution Ct Scans
Text-fig. 2. Metacheiromys marshii, AMNH 131777, drawing of basicranium in ventral view with isosurface from CT scans of left petrosal inserted (compare with Simpson 1931: fig. 7). Much of the mastoid exposure on the specimen's left side is damaged. Numbers 1 to 4 indicate depressions that based on the right side include a thin layer of entotympanic; 1 to 3 are between petrosal and basioccipital and 4 is petrosal only. The white arrow in the lower left passes through a canal between the petrosal and exoccipital for the auricular branch of the vagus nerve. Abbreviations: abX – grooves and foramina for auricular branch of vagus nerve, as – alisphenoid, astp – alisphenoid tympanic process, bo – basioccipital, bs – basisphenoid, eam – roof of external acoustic meatus, ec – ectotympanic, en – entotympanic, eo – exoccipital, es – epitympanic sinus of squamosal, fm – foramen magnum, fo – foramen ovale, gf – glenoid fossa, hf – hypoglossal foramen, ips – foramen for inferior petrosal sinus, ljf – lateral jugular foramen, me – mastoid exposure of petrosal, mjf – medial jugular foramen, mt – muscular tubercle, mtc – musculotubal canal, oc – occipital condyle, pa – porus acousticus (hidden), pas – parasphenoid, pgp – postglenoid process, pr – promontorium of petrosal, ps – presphenoid, smf – stylomastoid foramen, sof – superior orbital fissure, sq – squamosal, tca – tympanic canaliculus, th – tympanohyal, tm – tubular external acoustic meatus.
Text-fig. 42. Scanning electron microscope (SEM, a, b, e) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c, d, f–g) images of "Tricarpellate flower sp. 1"; Catefica locality, Portugal. a, b) Flower bud in two different lateral views showing semiinferior ovary and perianth; c) Longitudinal section (orthoslice yz0340) through flower bud in (a and b) showing the semi-inferior gynoecium and perigynous insertion of other floral parts; d) Volume rendering of flower bud with pedicel preserved; note the depression/split in one of the corner apparently separating two perianth lobes of the outer perianth whorl (t-o) and exposing one tepal of the inner whorl (t-i); e) Flower bud with pedicel preserved; note broad tepals of the outer whorl (t-o) and tepal of the inner whorl abraded exposing a broad stamen (st); f, g) Transverse sections through flower bud in (a and b) at two different levels above the insertion of the perianth (f, rec-file 1310; g, xy0280) showing the trimerous organization of the flower and the free, laterally flattened carpels; yellow indicates the two whorls of the androecium, each with three stamens. Specimens, Catefica 50-S171520 (a–c, f), Catefica 50-S174902 (d), Catefica MM154-P0271 (e), Catefica 49-S175354 (g). Scale bars = 300 Μm (a–e). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 42. Scanning electron microscope (SEM, a, b, e) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c, d, f–g) images of "Tricarpellate flower sp. 1"; Catefica locality, Portugal. a, b) Flower bud in two different lateral views showing semiinferior ovary and perianth; c) Longitudinal section (orthoslice yz0340) through flower bud in (a and b) showing the semi-inferior gynoecium and perigynous insertion of other floral parts; d) Volume rendering of flower bud with pedicel preserved; note the depression/split in one of the corner apparently separating two perianth lobes of the outer perianth whorl (t-o) and exposing one tepal of the inner whorl (t-i); e) Flower bud with pedicel preserved; note broad tepals of the outer whorl (t-o) and tepal of the inner whorl abraded exposing a broad stamen (st); f, g) Transverse sections through flower bud in (a and b) at two different levels above the insertion of the perianth (f, rec-file 1310; g, xy0280) showing the trimerous organization of the flower and the free, laterally flattened carpels; yellow indicates the two whorls of the androecium, each with three stamens. Specimens, Catefica 50-S171520 (a–c, f), Catefica 50-S174902 (d), Catefica MM154-P0271 (e), Catefica 49-S175354 (g). Scale bars = 300 Μm (a–e).
Text-fig. 44. Scanning electron microscope (SEM, a, b) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c, d) images of "Hexacarpellate flower". a) Lateral view of flower showing epigynous organization with remains of tepals inserted at top of the hypanthium; b) Detail of apical part of flower showing laminar structures (arrows) that may be stamen bases, adhering to, or fused with, the tepals; c) Longitudinal section (orthoslice yz0540) of flower through the median plane showing the epigynous organization and central axis with ovules (arrows); d) Transverse section (orthoslice xy1250) through the ovary of the flower showing the hexagonal outline, the six locules and ovules (arrows) borne near the center of the gynoecium. Specimen, Catefica 153-S174313 (a–d). Scale bars = 300 Μm (a, c), 100 Μm (b, d). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 44. Scanning electron microscope (SEM, a, b) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c, d) images of "Hexacarpellate flower". a) Lateral view of flower showing epigynous organization with remains of tepals inserted at top of the hypanthium; b) Detail of apical part of flower showing laminar structures (arrows) that may be stamen bases, adhering to, or fused with, the tepals; c) Longitudinal section (orthoslice yz0540) of flower through the median plane showing the epigynous organization and central axis with ovules (arrows); d) Transverse section (orthoslice xy1250) through the ovary of the flower showing the hexagonal outline, the six locules and ovules (arrows) borne near the center of the gynoecium. Specimen, Catefica 153-S174313 (a–d). Scale bars = 300 Μm (a, c), 100 Μm (b, d).
Simulation data for: "Unique Amphipathic a-helix Drives Membrane Insertion and Enzymatic Activity of ATG3"
<p>Simulation data from Nishimura et al. (2023), "Unique Amphipathic a-helix Drives Membrane Insertion and Enzymatic Activity of ATG3".</p> <p>The dataset contains the MD simulations executed for the Atg3/LC3/lipid membrane system, both in the WT and 5W-mutated variants.</p> <p>More information can be found in the README file and in Table 1 of the cited paper.</p> <p> </p>
Dataset on PowerWorld Software Power Flow Calculations on an Underground Distribution Feeder for Inserting Renewable Distribution Generation from Biogas, Photovoltaic and Small Wind Sources
<p>This Dataset brings all the information, details and source files used for power flow studies of the USP-105 underground feeder of the distribution medium voltage network in the University of São Paulo campus, which has received several embedded DG sources, namely a biogas plant, photovoltaic units and a small wind turbine.</p> <p>The power flow simulations were realized using the PowerWorldTM Simulator, v.23</p> <p>The files types on the Dataset are: </p> <p>.pwb, .pwd and tsb: Powerworld software input files for the simulations</p> <p>.csv: where a semicolon symbol (;) is used as a column separator, while a dot symbol (.) represents the decimal separator. The first row of each CSV file corresponds to the header row to help identify data.</p>
Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
ClinicalTrials.gov study NCT04168112. IPD Sharing: NO. Countries: 1. Publications: 13.
A 63-bp insertion in exon 2 of the porcine KIF21A gene is associated with arthrogryposis multiplex congenita
<p>This dataset includes genotype and phenotype data of 11 affected (case) and 23 unaffected (control) pigs for AMC case-control haplotype association testing and a VCF file of 809 candidate variants compatible with recessive inheritance of AMC.</p> <ol> <li>Genotype data (AMC.bed, AMC.bim and AMC.fam): 34 pigs genotyped with Illumina PorcineSNP60 Genotyping Bead chips.</li> <li>Phenotype data (AMC.pheno): the first, second and third column is Family ID, Animal ID and phenotype (1=case;2=control), respectively.</li> <li>AMC candidate variants compatible with recessive inheritance (AMC_candidate_muations.vcf.gz and AMC_candidate_muations.vcf.gz.tbi). Sequencing data of five animals in AMC pedigree have also been deposited at the Sequence Read Archive of the NCBI at the BioProject PRJNA622908 under sample accessions SAMN14532191, SAMN14532478, SAMN14532769, SAMN14532790 and SAMN14532792.</li> </ol>
Figure 21. Inserting a in DELTA for Beginners. An introduction into the taxonomy software package DELTA
Figure 21. Inserting a Cancel button and additional text overlays on a character illustration.
ProTInSeq: transposon insertion tracking by ultra-deep DNA sequencing applied to identify small and large translated ORFs
<p>ProTInSeq is a novel -omics technique designed to characterize proteomes by using DNA ultra-deep sequencing. The technique is based on transposons engineered to have a positive or negative protein selection marker expressed when the transposon is inserted in-frame into a protein-coding gene. In the genome-reduced bacterium Mycoplasma pneumoniae, ProTInSeq identifies 80% of known expressed proteins, as well as 5 new open reading frames (ORFs; >100 amino acids); and 153 novel small ORF-encoded proteins (SEPs; ≤100 aa) that represent up to 18% of this bacterium’s proteome. ProTInSeq can be used to detect translational noise, for protein quantification and to provide insight into functional protein aspects such as relative half-life, stability, and membrane topology. Herein, we describe a methodology that can be easily implemented in any living system and allows the deep understanding of proteomes and more importantly the identification of small proteins by DNA ultra-sequencing.</p> <p>We include the following files:</p> <p>- processed_inscalling.zip: output obtain after running FASTQINS transposon calling tool over the datasets found at <a href="https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-10380?key=5f54209d-ce59-490a-9bcd-7084e9c619ee">https://www.ebi.ac.uk/biostudies/arrayexpress/studies/E-MTAB-10380?key=5f54209d-ce59-490a-9bcd-7084e9c619ee</a>. This include every genome position in <em>M. pneumoniae</em>, the number of times an insertion has been mapped to that position and the total read count value.</p> <p>- separated_library_metrics.zip: insertion and read count processed from processed_inscalling files associated to every ORF and intergenic region in <em>M. penumoniae. </em>Columns include frame measured (0 - whole gene, 1 - in-frame, 2 and 3 for following positions) and metric. Metrics account for number insertions in-frame (<em>I</em>), read count (<em>R</em>), linear density from non-coding regions used in the Poisson evaluation (<em>rNC</em>), probability measured (<em>sfNC</em>) and a binary for prediction (<em>pred</em>; 0 - no significant, 1 - significant).</p> <p>- allmetrics.xlsx: merged table with the combination of results from separated_library_metrics.zip tab-delimited files.</p> <p>- selective_metrics_allannotations.xlsx: this table includes all the available information about the 30,112 sequences that could encode for a coding sequence in <em>M. pneumoniae</em>. For each identifier (column B), we include coordinates information and nucleotide and amino acid length information (columns C-H). Column I includes the gene name when the entry is found annotated in <em>M. pneumoniae</em>. Localization and function are described in columns J and K. Column L includes the operon number in which the annotation would be expressed. We also included transcription-related information average expression (column M; as log2(gene read count/gene length) and estimated average RNA copies per cell (column N) considering 4 RNA sequencing samples covering different growth times (6, 24 and 48 hours, ArrayExpress identifier E‐MTAB‐6203). Column O accounts for the number of mass spectrometry experiments detecting that entry (to a maximum of 116) and column P accounts for the total number of unique tryptic peptides detected. This comes <a href="https://paperpile.com/c/BImj5N/eljz">[5]</a>, available for 12,426 sequences that present an amino acid length ≥19 (from 116 mass spectrometry experiments, ID PRIDE: PXD008243). Columns Q to T recapitulate protein copies per cell under different conditions (overall, extracting with urea, extracting with SDS and mean, respectively). Column U includes half-lives of the proteins. Columns V and W describe the reference density of insertion and essentiality assigned in previous studies. Column X-AA includes the predicted RanSEPs score, ribosome binding site presence, homology into seven groups: 0—no hits passed the thresholds defined; 1—conserved with an annotated function; 2—conserved as an annotated SEP in NCBI but no associated function; 3—conserved in a different species but target and homologous sequence not found in NCBI; 4—sequence is completely or partially (> 75%) repeated ≥ 3 times in the reference genome; 5—potential pseudogene; and 6—to depict those annotations that are found in the reference NCBI annotation file. , and function expected by homology, respectively. Columns AB to AD cover the output provided by Phobius, including the number of transmembrane segments, presence of signal peptide and transmembrane topology predicted by TM-HMM. Column AE includes the complex information where 1 implies that entry is functional as a monomer, 2 as dimer, and so on. Finally, columns AF-AH will be 1 if the protein is a Lon protease target, a lipoprotein, and/or a truncated gene or pseudogene, respectively, 0 otherwise. Following columns include for every sample presenting selective insertion rates in-frame using the following identifiers separated by underscores: marker (BarnB, Cm or Ery), type (control-AC or selection-BD, antibiotic concentration, sample replicate, frame measured, metric. Metrics account for number insertions in-frame (<em>I</em>), read count (<em>R</em>), linear density from non-coding regions used in the Poisson evaluation (<em>rNC</em>), probability measured (<em>sfNC</em>) and a binary for prediction (<em>pred</em>; 0 - no significant, 1 - significant). Last columns combine the number of samples each annotation has been identified. Notice for barnase library the results need to be interpreted considering it is a negative selection marker inverting the 0 and 1 meaning.</p>
Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells
<p>The manuscript describes the use of ssDNA with chemical modifications in internal bases to improve gene insertion. The dataset contains an excel file with the data corresponding to the figures in this manuscript. In addition, it has results from next-generation sequencing used in Figure 2B. </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.