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814 results for “LPS”
Drone eviction assay raw data from Gilchrist et al for drone weights and eviction rates that have been treated with LPS or not
<p>Across the animal kingdom, males advertise their quality to potential mates. Males of low reproductive quality, such as those that are sick, may be excluded from mating. In eusocial species, there is some evidence that reproductive females gauge the quality of their mates. However, males often spend much more time with non-reproductive females as they are raised or, for some species, when they return from unsuccessful mating flights. Do non-reproductive workers evaluate the quality of male reproductives? Here we address this question using male honey bees (<em>Apis mellifera</em>), called drones, as a model. We generated immune-challenged drones by injecting them with lipopolysaccharide and tested: 1) do workers evict immune-challenged drones from their colony, 2) do cuticular hydrocarbon (CHC) profiles, body size, or mass change when drones are immune-challenged, and 3) are these changes used by workers to exclude low quality males from the colony? We found that an immune challenge causes changes in CHC profiles of drones and reduces their body mass. Workers selectively evict small and immune-challenged drones who, themselves, do not self-evict. This work demonstrates that some eusocial males undergo an additional layer of scrutiny prior to mating, one mediated by the nonreproductive worker caste.</p>
Data for Characterization of cytokine response to intraperitoneally administered LPS & subdiaphragmatic branch vagus nerve stimulation in rat model
<p>These are the data files used for publication "Characterization of cytokine response to intraperitoneally administered LPS & subdiaphragmatic branch vagus nerve stimulation in rat model" to be published in PLOS ONE.</p>
Fig 5 in Docosahexaenoic Acid (DHA) Reduces LPS-Induced Inflammatory Response Via ATF3 Transcription Factor and Stimulates Src/Syk Signaling-Dependent Phagocytosis in Microglia
Open the record for dataset details and reuse information.
Fig 4 in Docosahexaenoic Acid (DHA) Reduces LPS-Induced Inflammatory Response Via ATF3 Transcription Factor and Stimulates Src/Syk Signaling-Dependent Phagocytosis in Microglia
Open the record for dataset details and reuse information.
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data
<p>Anti-cytokine storm activity of fraxin and quercetin, alone and in combination, and their possible molecular mechanisms via TLR4 and PPARγ signaling pathways in LPS-induced RAW 264.7 cell line article data</p>
Fig. 8. Ochrathinols A in Ochrathinols A and B, two pairs of sulfur-containing racemates from an Antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702 inhibit LPS-induced pro-inflammatory cytokines and NO production
Fig. 8. Ochrathinols A (±)-1 compensated the NAD+/NADH ratio induced by LPS. Cells were exposed to 0.1 μg/mL LPS and co-treated with compounds of (±)-1 (10 μM) for 24 h. Intracellular NAD+/NADH ratios were determined by NAD+/NADH assay kit. Data are shown as mean ± SD (n = 3). *P <0.05, ****P <0.001 vs. LPS group, n = 3. P value was assessed by two-tailed Student's t-test.
Fig. 7 in Ochrathinols A and B, two pairs of sulfur-containing racemates from an Antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702 inhibit LPS-induced pro-inflammatory cytokines and NO production
Fig. 7. Anti-inflammation activity of ochrathinols A and B ((±)-1, (±)-2). Cells were exposed to 0.1 μg/mL LPS and co-treated with compounds of (+)-1, ()-1, (±)-1, (+)-2, ()-2, (±)-2 (10 μM) for 24 h, respectively. (A) (±)-1 reduced the release of LPS-induced IL-6, TNF-α, and MCP-1 in culture medium, n = 3. (B) qPCR analysis of pro-inflammatory cytokines genes (IL-1β, IL-6, TNF-α, and MCP-1) normalized by β-actin, n = 3. All data are presented as the mean ± SD of three independent experiments. ns, P> 0.05, *P <0.05, **P <0.01, ***P <0.005, ****P <0.001 vs. LPS group; #P <0.05, ##P <0.01, ###P <0.005, ####P <0.001 vs. control group, n = 3. P value was assessed by two-tailed Student's t-test.
Fig. 6 in Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro
Fig. 6. Effects of 1 on iNOS, COX-2, and NF-κB protein expression in LPS-induced RAW 264.7 cells in vitro. "Dexamethasone" represents the positive control group, and "Control" represents the blank control, which was not treated with LPS or the tested compounds. (A) Protein expression of iNOS, COX-2, P65 and P–P65 was determined by Western blotting. (B) Relative protein expression of P–P65 to P65 is shown as a histogram. (C) Protein expression of iNOS and COX-2 relative to the control is shown as a histogram. The experiment was repeated three times. Data are presented as the mean ± SD. *P <0.05 vs. the LPS group, **P <0.01 vs. the LPS group.
Fig. 3 in Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro
Fig. 3. NMR calculation results of two plausible stereoisomers of 1 at the B3LYP-D3 (BJ)/6-31G** level.
Fig. 5 in Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro
Fig. 5. Effects of different concentrations (10, 20, 40 μM)) of 1 on LPS-stimulated release of (A) TNF-α, (B) IL-6, and (C) IL-1β in RAW 264.7 cells. The values represent the mean ± SD of three independent experiments, and differences between the mean values were assessed by Student's t-test. ##P <0.01 vs. the control group, *P <0.05 vs. the LPS group, **P <0.01 vs. the LPS group.
Fig. 4 in Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro
Fig. 4. Effect of 1–6 (40 μM) on NO release in LPS-induced RAW 264.7 cells in vitro. Dexamethasone was used as a positive control in this experiment, and the concentration was 5 μM. The data represent the mean ± SD of three independent experiments.
Fig. 4 in Lanostane-type triterpenoids from Ganoderma applanatum and their inhibitory activities on NO production in LPS-induced BV-2 cells
Fig. 4. Experimental (black line) and calculated (red line) ECD spectra of 1–5 (A–E) and their enantiomers in MeOH. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
PDE_LPS
<p>PDE LPS Dataset</p>
Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease
ClinicalTrials.gov study NCT01155492. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nitric Oxide, LPS and the Pathogenesis of Asthma Phase 1
ClinicalTrials.gov study NCT00671229. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nasal LPS Challenge in Healthy Volunteers
ClinicalTrials.gov study NCT02284074. IPD Sharing: Not stated. Countries: 1. Publications: 32.
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
ClinicalTrials.gov study NCT02086344. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Intrapulmonary Recombinant Human Activated Protein C (APC) on Coagulation and Inflammation After Lipopolysaccharide (LPS)
ClinicalTrials.gov study NCT00943267. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efferon LPS Hemoperfusion for Treatment of Patients With Septic Shock
ClinicalTrials.gov study NCT04884854. IPD Sharing: NO. Countries: 1. Publications: 13.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.