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50 results for “Microbial Metabolites”
Data from: Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease
Coronary heart disease (CHD) is top risk factor for health in modern society, causing high mortality rate each year. However, there is no reliable way for early diagnosis and prevention of CHD so far. So study the mechanism of CHD and development of novel biomarkers is urgently needed. In this study, metabolomics and metagenomics technology are applied to discover new biomarkers from plasma and urine of 59 CHD patients and 43 healthy controls and trace their origin. We identify GlcNAc-6-P which has good diagnostic capability and can be used as potential biomarkers for CHD, together with mannitol and 15 plasma cholines. These identified metabolites show significant correlations with clinical biochemical indexes. Meanwhile, GlcNAc-6-P and mannitol are potential metabolites originated from intestinal microbiota. Association analysis on species and function levels between intestinal microbes and metabolites suggest a close correlation between Clostridium sp. HGF2 and GlcNAc-6-P, Clostridium sp. HGF2, Streptococcus sp. M143, Streptococcus sp. M334 and mannitol. These suggest the metabolic abnormality is significant and gut microbiota dysbiosis happens in CHD patients.
Data for: Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites
<p>Data and sequencing raw files to reproduce the display items of the manuscript entitled "Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites"</p>
The Colonic Transit Time: a Modifiable Determinant of Intestinal Production and Uptake of Microbial Metabolites?
ClinicalTrials.gov study NCT01869751. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Microbial Metabolites and Outcomes of Pregnancy Study
ClinicalTrials.gov study NCT06362356. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Correlation of P-glycoprotein Polymorphisms With Microbial Metabolites in Patients With Alzheimer's Disease on Medication
ClinicalTrials.gov study NCT05532644. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Intestinal Transport of Microbial Metabolites in Chronic Kidney Disease
ClinicalTrials.gov study NCT01752738. IPD Sharing: Not stated. Countries: 1. Publications: 0.
the Association of Intestinal Microbial Metabolites and Cardiac Function in Acute Myocardial Infarction
ClinicalTrials.gov study NCT04955054. IPD Sharing: NO. Countries: 1. Publications: 0.
Gut Microbial Metabolites of Apple Polyphenols
ClinicalTrials.gov study NCT06107192. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation
ClinicalTrials.gov study NCT03925597. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease
Open the record for dataset details and reuse information.
ACE2 shedding exacerbates sepsis induced gut leak via loss of microbial metabolite 5-MTP
GEO Series GSE267002. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
A Surgical Method for Continuous Intra-Portal Infusion of Gut Microbial Metabolites in Mice
GEO Series GSE159775. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Microbial-Derived Metabolites Regulate the Colonic Crypt Niche
GEO Series GSE74601. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Use of RNA sequencing to assess the expression patterns of microbial metabolite transporters present in children post-transplant with and without GVHD
GEO Series GSE102228. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Phytogenic additive from mesquite to improve nutrient digestibility, microbial protein, ruminal parameters and blood metabolites in sheep
<p>Crude data of ingestive behavior of sheep.</p>
The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors
GEO Series GSE300937. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Enteric neuronal GPR41-DHX9 signaling senses microbial metabolites to mediate the crosstalk between serotonergic neurons and intestinal stem cells [RNA-seq]
GEO Series GSE253990. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Mannose enhances anti-PD-1 therapy efficacy in ovarian cancer via modulating gut microbial metabolite.
GEO Series GSE271477. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Gut microbial metabolite trimethylamine N-oxide aggravates pulmonary hypertension
GEO Series GSE190203. Rattus norvegicus. 8 samples. Type: Expression profiling by high throughput sequencing.
Mannose enhances anti-PD-1 therapy efficacy in ovarian cancer via modulating gut microbial metabolite [Peritoneum]
GEO Series GSE285965. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.