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701
datasets available to search
ShareScore release 0.9.0
Dataset results
701 results for “Neoplasms”
Blood Tests for Gastritis and Gastric Neoplasms
ClinicalTrials.gov study NCT05883345. IPD Sharing: NO. Countries: 1. Publications: 1.
PD-1 Inhibition in Advanced Myeloproliferative Neoplasms
ClinicalTrials.gov study NCT03065400. IPD Sharing: NO. Countries: 1. Publications: 1.
Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm
ClinicalTrials.gov study NCT01101880. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence
ClinicalTrials.gov study NCT03194542. IPD Sharing: Not stated. Countries: 4. Publications: 1.
Pilot Trial of a WT-1 Analog Peptide Vaccine in Patients With Myeloid Neoplasms
ClinicalTrials.gov study NCT00665002. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
ClinicalTrials.gov study NCT04035499. IPD Sharing: YES. Countries: 1. Publications: 5.
Characterizing and classifying neuroendocrine neoplasms through microRNA sequencing and data mining
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Survival Outcomes of Pancreatic Intraepithelial Neoplasm (PanIN) Versus Intraductal Papillary Mucinous Neoplasm (IPMN) Associated Pancreatic Adenocarcinoma
<p>Pancreatic intraepithelial neoplasms (PanINs) and intraductal papillary mucinous neoplasms (IPMNs) are common pancreatic adenocarcinoma precursor lesions. However, data regarding their respective associations with survival rate and prognosis are lacking. We retrospectively evaluated 72 pancreatic adenocarcinoma tumor resection patients at the University of Kansas Hospital between August 2009 and March 2019. Patients were divided into one of two groups, PanIN or IPMN, based on the results of the surgical pathology report. We compared baseline characteristics, overall survival (OS), and progression free survival (PFS) between the two groups, as well as OS and PFS based on local or distant tumor recurrence for both groups combined. 52 patients had PanINs and 20 patients had IPMNs. Patients who had an IPMN precursor lesion had better median PFS and OS when compared to patients with PanIN precursor lesions. However, the location of tumor recurrence (local or distant) did not show a statistically significant difference in OS.</p>
Risk Assessment and Radiomics Analysis in Magnetic Resonance Imaging of Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN)
<p>I uploaded the original images of the manuscript "Risk Assessment and Radiomics Analysis in Magnetic Resonance Imaging of Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN)" accepted for pubblication on Cancer Control.</p>
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms
<p></p><p>Most cancers become more dangerous by the outgrowth of malignant subclones with additional DNA mutations that favor proliferation or survival. Using chronic lymphocytic leukemia (CLL), a disease exemplary of this process, and a model for neoplasms in general, we created transgenic mice overexpressing the enzyme, activation-induced deaminase (AID), whose normal function is to induce DNA mutations in B lymphocytes. AID allows normal B lymphocytes to develop more effective immunoglobulin (Ig)-mediated immunity, but also is able to mutate non-Ig genes, predisposing to cancer. In chronic lymphocytic leukemia (CLL), AID expression correlates with poor prognosis suggesting a role for this enzyme in disease progression. Nevertheless, direct experimental evidence identifying the specific genes that are mutated by AID and indicating that those genes are associated with disease progression is not available. To address this point, we overexpressed Aicda in a murine model of CLL (Em-TCL1). Analyses of TCL1/AID mice demonstrate a role for AID in disease kinetics, CLL-cell proliferation, and the development of cancer-related target mutations with canonical AID signatures in non-Igs genes. Notably, our mouse models can accumulate mutations in the same genes that are mutated in human cancers. Moreover, some of these mutations occur at homologous positions, leading to identical or chemically-similar amino acid substitutions as in human CLL and lymphoma. Together, these findings support a direct link between aberrant AID activity and CLL driver mutations that are then selected for their oncogenic effects, whereby AID promotes aggressiveness in CLL and other B-cell neoplasms.</p><p></p>
A WT1-positive pleural neoplasm. Is it always a mesothelioma? Diagnostic pitfall of WT1 immunohistochemistry in pleural neoplasm
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Dual Vaccine Trial in Myeloproliferative Neoplasms
ClinicalTrials.gov study NCT04051307. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Cervical Intraepithelial Neoplasm (CIN) in Women (Gardasil) (V501-015)
ClinicalTrials.gov study NCT00092534. IPD Sharing: YES. Countries: 0. Publications: 33.
Colonic Capsule Endoscopy (CCE) for Screening of Neoplasm's A Pilot Study
ClinicalTrials.gov study NCT02303756. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Metronomic Temozolomide in Unfit NENs Patients Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe Study
ClinicalTrials.gov study NCT05554003. IPD Sharing: NO. Countries: 1. Publications: 3.
Asymptomatic Small Pancreatic Endocrine Neoplasms.
ClinicalTrials.gov study NCT03084770. IPD Sharing: NO. Countries: 1. Publications: 23.
Carotid Plaque Burden in Patients With Philadelphia Negative Myeloproliferative Neoplasms
ClinicalTrials.gov study NCT05993052. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Diaphragmatic Resection And Gynecological Ovarian Neoplasm
ClinicalTrials.gov study NCT03543462. IPD Sharing: UNDECIDED. Countries: 1. Publications: 13.
Clinical Database and Biobank of Patients With Gynecologic Neoplasms
ClinicalTrials.gov study NCT01267851. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of Venetoclax, a BCL2 Antagonist, for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
ClinicalTrials.gov study NCT03485547. IPD Sharing: NO. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.