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37 results for “Onchocerca”

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zenodo40/100

Fig. 2 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 2. Worm burden in situ of sternal skin in the process of digestion. Most of these worm fragments could be identified as Onchocerca skrjabini, no O. garmsi was found.

opencc-by-4.0Dec 2022View details →
zenodo40/100

Fig. 1 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 1. Onchocerca skrjabini in situ in carpal skin. A. Freshly cut piece of skin shown from inside (note turned around piece of fur on top). Added methylene blue stains the O. skrjabini specimens and makes them visible for the naked eye. B. Parasitic burden in the same piece of skin in process of digestion. Hair follicles seen as dark dots. Fragments of O. skrjabini show different body width. Note very thin anterior headends (arrows). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

opencc-by-4.0Dec 2022View details →
zenodo40/100

Fig. 12 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 12. Onchocerca skrjabini: two microfilariae protrude from broken frontal part of a female, showing very tight setting in small anterior body part in this species. Note subapical oval mark with protruding rim on head of microfilaria.

opencc-by-4.0Dec 2022View details →
zenodo40/100

Fig. 11 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 11. Different body width of one specimen of Onchocerca skrjabini in comparison. Midbody at left, tapering part in the middle, thin anterior body at right. Note Onchocerca typical structure of cuticle with ridges on the surface and striae in medulla in ratio 1: 4.

opencc-by-4.0Dec 2022View details →
zenodo40/100

Fig. 13 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 13. Onchocerca skrjabini female: cuticular ridges do not meet over the lateral line, they taper and disappear distant from each other.

opencc-by-4.0Dec 2022View details →
zenodo36/100

Fig. 6. O in First description of Onchocerca jakutensis (Nematoda: Filarioidea) in red deer (Cervus elaphus) in Switzerland

Fig. 6. O. jakutensis female: Ratio of cuticular annulation (A) to medullar striae (S) 1:4.

opencc-by-4.0Aug 2016View details →
zenodo36/100

Fig. 2 in First description of Onchocerca jakutensis (Nematoda: Filarioidea) in red deer (Cervus elaphus) in Switzerland

Fig. 2. Anterior end of O. jakutensis female, with granular lumps in process of degeneration.

opencc-by-4.0Aug 2016View details →
zenodo36/100

Fig. 9 in Morphological description and multilocus genotyping of Onchocerca spp. in red deer (Cervus elaphus) in Switzerland

Fig. 9. Detail of Onchocerca flexuosa female: Uterine tubes (arrow) straightened inside curly body.

opencc-by-4.0Dec 2022View details →
dryad36/100

Data from: Positive allosteric modulation of emodepside sensitive <em>Brugia malayi</em> SLO-1F and <em>Onchocerca volvulus</em> SLO-1A potassium channels by GoSlo-SR-5-69

Open the record for dataset details and reuse information.

publicSep 2025View details →
dryad36/100

Data from: Effects of emodepside on single-channel properties of <em>Onchocerca volvulus</em> SLO-1A (BK) potassium channels

Open the record for dataset details and reuse information.

publicSep 2025View details →
zenodo32/100

Dataset for study on In vitro analysis of the effects of analgesics on the motility of female adult Onchocerca volvulus worms

<p>Dataset on the effects of acetaminophen, ibuprofen and aspirin on the motility of Onchocerca volvulus parasites. The measurements were done with the WormAssay Software over the course of 7 days.</p>

opencc-by-4.0Feb 2023View details →
ClinicalTrials.gov32/100

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

ClinicalTrials.gov study NCT00790998. IPD Sharing: Not stated. Countries: 3. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

ClinicalTrials.gov study NCT00300768. IPD Sharing: NO. Countries: 1. Publications: 1.

closedIPD-NOFeb 2026View details →
dryad32/100

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

Open the record for dataset details and reuse information.

publicMay 2021View details →
zenodo28/100

Nodding Syndrome, a Case-control Study in Mahenge, Tanzania: Onchocerca volvulus and not Mansonella perstans as Risk Factor

<p><strong>Background</strong>: Nodding syndrome (NS) has been consistently associated with onchocerciasis. Nevertheless, a positive association between NS and a <em>Mansonella perstans</em> infection was found in South Sudan. We aimed to determine whether the latter parasite could be a risk factor for NS in Mahenge.</p> <p><strong>Methods</strong>: Cases of epilepsy were identified in villages affected by NS in Mahenge, Tanzania, and matched with controls without epilepsy of the same sex, age and village. We examined blood films of cases and controls to identify <em>M. perstans</em> infections. The participants were also asked for sociodemographic and epilepsy information, examined for palpable onchocercal nodules and onchocerciasis-related skin lesions and tested for anti-<em>Onchocerca volvulus</em> antibodies (Ov16 IgG4) by ELISA. Clinical characteristics of cases and controls, <em>O. volvulus </em>exposure status and relevant sociodemographic variables were assessed by a conditional logistic regression model for NS and epilepsy status matched for age, sex and village.</p> <p><strong>Results</strong>: A total of 113 epilepsy cases and 132 controls were enrolled, of which, respectively, 56 (49.6%) and 64 (48.5%) were men. The median age in cases and controls was 28.0 (IQR: 22.0&ndash;35.0) and 27.0 (IQR: 21.0-33.3) years. Of the persons with epilepsy, 43 (38.1%) met the probable NS criteria and 106 (93.8%) had onchocerciasis-associated epilepsy (OAE). <em>M. perstans</em> infection was absent in all participants, while Ov16 seroprevalence was positively associated with probable NS (odds ratio (OR): 5.05, 95%CI: 1.79&ndash;14.27) and overall epilepsy (OR: 2.03, 95%CI: 1-07&ndash;3.86). Moreover, onchocerciasis-related skin manifestations were only found in the cases (n = 7, p=0.0040), including persons with probable NS (n=4, p=0.0033). Residing longer in the village and having a family history of seizures were positively correlated with Ov16 status and made persons at higher odds for epilepsy, including</p>

opencc-by-4.0Jun 2023View details →
geo24/100

Onchocerca-derived small RNAs in host nodules and serum

GEO Series GSE63933. Homo sapiens; Bos taurus. 5 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenApr 2015View details →
geo20/100

Vaccination against Onchocerca volvulus induces IgG-mediated protective immunity dependent on neutrophils and complement

GEO Series GSE295728. Mus musculus. 47 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →

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International Brain Laboratory public data

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