Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
482
datasets available to search
ShareScore release 0.9.0
Dataset results
482 results for “Pituitary”
Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors
ClinicalTrials.gov study NCT02351700. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to Corticosteroids Intrabursal Injection
ClinicalTrials.gov study NCT01652495. IPD Sharing: Not stated. Countries: 1. Publications: 6.
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
ClinicalTrials.gov study NCT00001595. IPD Sharing: YES. Countries: 1. Publications: 17.
Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors
ClinicalTrials.gov study NCT04042753. IPD Sharing: YES. Countries: 1. Publications: 1.
Hypothalamic-Pituitary-Adrenal (HPA)-Axis Study in Pediatric Subjects With Perennial Allergic Rhinitis (PAR)
ClinicalTrials.gov study NCT01697956. IPD Sharing: Not stated. Countries: 1. Publications: 1.
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
ClinicalTrials.gov study NCT01185782. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy
ClinicalTrials.gov study NCT00939523. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of Fluticasone Furoate Inhalation Powder on the Hypothalamic-pituitary-adrenocortical Axis of Children Aged 5-11 Years With Asthma
ClinicalTrials.gov study NCT02483975. IPD Sharing: YES. Countries: 2. Publications: 1.
Integrating methylome and transcriptome signatures expands the molecular classification of the pituitary tumors
Open the record for dataset details and reuse information.
Data from: The fish pituitary directly responds to daylength and drives seasonality:
Open the record for dataset details and reuse information.
Data from: anterior pituitary transcriptomics following a high fat diet: impact of oxidative stress on cell metabolism
Open the record for dataset details and reuse information.
Data from: PCSK1N as a tumor size marker and an ER stress response protein in corticotroph pituitary adenomas
Open the record for dataset details and reuse information.
Association between preoperative medication lists and postoperative hospital length of stay after endoscopic transsphenoidal pituitary surgery
Open the record for dataset details and reuse information.
Bulk RNAseq of chronic LPS treated female mouse pituitary across doses
Open the record for dataset details and reuse information.
Interleukin-6 response to insulin-induced hypoglycemia is associated with hypothalamic-pituitary-adrenal axis activation
<p>Raw data (excel table) concerning 23 patients who underwnt ITT for evaluation of IL-6 and counter-regulatory responses </p>
Control of the anterior pituitary cell lineage regulator POU1F1 by the stem cell determinant Musashi
<p><span><span><span><span><span><span><span><span><span><span><span>The cytokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in the brain, including cells of the anterior pituitary (AP). We have previously reported that mice lacking leptin receptors in AP somatotropes display growth hormone (GH) deficiency, metabolic dysfunction and adult onset obesity. Amongst other targets, leptin signaling promotes increased levels of the pituitary transcription factor POU1F1 (also referred to as Pit1) which, in turn, regulates the specification of somatotrope, lactotrope and thyrotrope cell lineages within the anterior pituitary. Leptin's mechanism of action on somatotropes is sex-dependent, with females demonstrating post-transcriptional control of <i>Pou1f1 </i>mRNA translation. In this study, we have investigated the mechanism that regulates <i>Pou1f1 </i>mRNA translational control and report that the stem cell marker and mRNA translational control protein, Musashi1, exerts repression of the <i>Pou1f1</i> mRNA. In FACS-purified female somatotropes, <i>Msi1</i> mRNA levels and Musashi1 protein levels are increased in the mouse model that lacks leptin signaling (<i>Gh</i>-CRE <i>Lepr</i>-null), coincident with lack of POU1f1 protein, despite normal levels of <i>Pou1f1</i> mRNA. Single-cell RNA sequencing of pituitary cells from control female animals indicates that both <i>Msi1</i> and <i>Pou1f1 </i>mRNAs are expressed in <i>Gh</i>-expressing somatrotropes and immunocytochemistry analyses of these cells confirms that Musashi1 protein is present in the somatotrope population. We demonstrate that Musashi interacts directly with the <i>Pou1f1</i> mRNA 3' untranslated region and exerts translational repression of a <i>Pou1f1 </i>mRNA translation<i> </i>reporter in a leptin-sensitive manner.<i> </i> Musashi immunoprecipitation from whole pituitary reveals co-associated <i>Pou1f1 </i>mRNA. These findings suggest a mechanism in which leptin stimulation is required to reverse Musashi-mediated <i>Pou1f1 </i>mRNA translational control to coordinate AP somatotrope function with metabolic status.</span></span></span></span></span></span></span></span></span></span></span></p>
Pannexin-1 promotes the invasion of pituitary adenoma by modulating ATP release
Open the record for dataset details and reuse information.
Grape Polyphenols may prevent high fat diet-induced dampening of the hypothalamic-pituitary-adrenal axis in male mice
<p>Supplementary Materials. </p>
SUSTAINED PITUITARY T3 PRODUCTION EXPLAINS THE T4-MEDIATED TSH FEEDBACK MECHANISM
<p>Supplemental data for the manuscript "Sustained pituitary T3 production explains the T4-mediated TSH feedback"</p>
Postoperative Cognitive Dysfunction in Transsphenoidal Pituitary Surgeries
ClinicalTrials.gov study NCT06793150. IPD Sharing: NO. Countries: 1. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.