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72 results for “Pyrrole”
Figure 4 from: Tzankova D, Peikova L, Vladimirova S, Georgieva M (2019) Development and validation of RP-HPLC method for stability evaluation of model hydrazone, containing a pyrrole ring. Pharmacia 66(3): 127-134. https://doi.org/10.3897/pharmacia.66.e47035
Figure 4 Chromatogram of standard solution of the aldehyde d (tR = 1.283) as possible degradation product.
Figure 3 from: Tzankova D, Peikova L, Vladimirova S, Georgieva M (2019) Development and validation of RP-HPLC method for stability evaluation of model hydrazone, containing a pyrrole ring. Pharmacia 66(3): 127-134. https://doi.org/10.3897/pharmacia.66.e47035
Figure 3 Chromatogram of standard solution of the hydrazide D-5 (tR = 4.380) as possible degradation product.
Figure 8 from: Tzankova D, Peikova L, Vladimirova S, Georgieva M (2019) Development and validation of RP-HPLC method for stability evaluation of model hydrazone, containing a pyrrole ring. Pharmacia 66(3): 127-134. https://doi.org/10.3897/pharmacia.66.e47035
Figure 8 Chromatograms indicating the behavior of D_5d in the presence of buffer with pH 9.0 and at 37°C at 0th min (A) and at 210th min (B).
Figure 9 from: Tzankova D, Peikova L, Vladimirova S, Georgieva M (2019) Development and validation of RP-HPLC method for stability evaluation of model hydrazone, containing a pyrrole ring. Pharmacia 66(3): 127-134. https://doi.org/10.3897/pharmacia.66.e47035
Figure 9 Chromatograms indicating the behavior of D_5d in the presence of buffer with pH 13.0 and at 37°C at 0th min (A) and at 30th min (B).
Direct Targeting of MYCN Gene Amplification by Alkylating Pyrrole-Imidazole Polyamide and CRISPR/Cas9 in Neuroblastoma Cells (CHP-134)
GEO Series GSE121530. Homo sapiens. 13 samples. Type: Expression profiling by array.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (MC-IXC cells)
GEO Series GSE124458. Homo sapiens. 6 samples. Type: Expression profiling by array.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach
GEO Series GSE124462. Homo sapiens. 40 samples. Type: Expression profiling by array.
Alkylating pyrrole-imidazole polyamide KR12 binding in colorectal cancer genomes (LS180)
GEO Series GSE86597. Homo sapiens. 8 samples. Type: Expression profiling by array.
Targeted suppression of metastasis controlling transcription factor SOX2 in various cancers using a sequence-specific designer Pyrrole-Imidazole Polyamide
GEO Series GSE138617. Homo sapiens. 2 samples. Type: Expression profiling by array.
Alkylating pyrrole-imidazole polyamide KR12 binding in colorectal cancer genomes
GEO Series GSE86599. Homo sapiens. 14 samples. Type: Expression profiling by array.
Novel therapeutic strategy targeting STMN1 using chlorambucil-conjugated pyrrole-imidazole polyamide in small cell lung cancer
GEO Series GSE281782. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (SiHA cells)
GEO Series GSE124460. Homo sapiens. 5 samples. Type: Expression profiling by array.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (SK-N-AS cells)
GEO Series GSE124461. Homo sapiens. 6 samples. Type: Expression profiling by array.
Use of DNA-alkylating pyrrole-imidazole polyamides for anti-cancer drug sensitivity screening in PDAC
GEO Series GSE208243. Homo sapiens. 16 samples. Type: Expression profiling by array.
Alkylating pyrrole-imidazole polyamide KR12 binding in colorectal cancer genomes (SW480)
GEO Series GSE86598. Homo sapiens. 6 samples. Type: Expression profiling by array.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (CHP-134 cells)
GEO Series GSE124456. Homo sapiens. 6 samples. Type: Expression profiling by array.
Direct Targeting of MYCN Gene Amplification by Alkylating Pyrrole-Imidazole Polyamide in Neuroblastoma Cells (CHP-134)
GEO Series GSE121528. Homo sapiens. 5 samples. Type: Expression profiling by array.
Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide
GEO Series GSE108265. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Estimating Genome-wide Off-Target Effects for Pyrrole-Imidazole Polyamide Binding by a Pathway-Based Expression Profiling Approach (CaSki cells)
GEO Series GSE124455. Homo sapiens. 5 samples. Type: Expression profiling by array.
Figure 2 from: Mateev E, Irfan A, Mateeva A, Kondeva-Burdina M, Georgieva M, Zlatkov A (2024) In silico and in vitro screening of pyrrole-based Hydrazide-Hydrazones as novel acetylcholinesterase inhibitors. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e114120
Figure 2 General core structure of the employed in-house database.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.